Non-invasive image-guided targeted drug delivery of radium nanoparticles in human gum cancer cells, tissues and tumors treatment under synchrotron radiation

A. Heidari, K. Schmitt, M. Henderson, E. Besana
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引用次数: 10

Abstract

In the current study, thermoplasmonic characteristics of Radium nanoparticles with spherical, core-shell and rod shapes are investigated. In order to investigate these characteristics, interaction of synchrotron radiation emission as a function of the beam energy and Radium nanoparticles were simulated using 3D finite element method. Firstly, absorption and extinction cross sections were calculated. Then, increases in temperature due to synchrotron radiation emission as a function of the beam energy absorption were calculated in Radium nanoparticles by solving heat equation. The obtained results show that Radium nanorods are more appropriate option for using in optothermal human cancer cells, tissues and tumors treatment method. of with
无创图像引导靶向药物递送镭纳米粒子在同步辐射下治疗人牙龈癌细胞、组织和肿瘤
在本研究中,研究了球形、核壳和棒状镭纳米粒子的热等离子体特性。为了研究这些特性,采用三维有限元方法模拟了同步辐射发射与镭纳米粒子的相互作用。首先计算了吸收和消光截面。然后,通过求解热方程,计算了镭纳米粒子中同步辐射发射引起的温度升高与光束能量吸收的关系。所获得的结果表明,镭纳米棒是更合适的选择,用于光热人体癌细胞、组织和肿瘤的治疗方法。的
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