Impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells
{"title":"Impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells","authors":"A. Heidari, R. Gobato","doi":"10.15761/DOMR.1000371","DOIUrl":null,"url":null,"abstract":"In the current paper, impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells are studied. After diagnosis the primary treatment for solid tumors is often surgery. The objective of surgical treatment is resection of all malignant tissue with adequate resection margins while preserving important healthy structures. Achieving adequate surgical margins is important for disease control and survival. Residual tumor after surgery is associated with poor survival and the need for additional surgery, adjuvant chemotherapy, radiation therapy, or impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells. A number of studies have shown that the 5–year survival decreases significantly when impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells. Intraoperative guidance tools can help to achieve adequate surgery. However, there are no widely used intraoperative guidance tools available yet. Current surgical resection techniques are based on subjective methods, such as palpation and visual inspection, to judge the border between normal and cancerous tissue. line of a multi–state DNA/RNA ligand binding","PeriodicalId":10996,"journal":{"name":"Dental, Oral and Maxillofacial Research","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"12","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dental, Oral and Maxillofacial Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15761/DOMR.1000371","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 12
Abstract
In the current paper, impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells are studied. After diagnosis the primary treatment for solid tumors is often surgery. The objective of surgical treatment is resection of all malignant tissue with adequate resection margins while preserving important healthy structures. Achieving adequate surgical margins is important for disease control and survival. Residual tumor after surgery is associated with poor survival and the need for additional surgery, adjuvant chemotherapy, radiation therapy, or impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells. A number of studies have shown that the 5–year survival decreases significantly when impact of DNA/RNA self–alignment in a strong magnetic field on the interpretation of indirect spin–spin interactions using NMR line shape analysis of a multi–state DNA/RNA ligand binding mechanism in gum cancer cells. Intraoperative guidance tools can help to achieve adequate surgery. However, there are no widely used intraoperative guidance tools available yet. Current surgical resection techniques are based on subjective methods, such as palpation and visual inspection, to judge the border between normal and cancerous tissue. line of a multi–state DNA/RNA ligand binding