Current opinion in pediatrics最新文献

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Linking household members and defining relational networks using routine health data. 利用常规健康数据将家庭成员联系起来并定义关系网络。
IF 2.2 3区 医学
Current opinion in pediatrics Pub Date : 2025-02-01 Epub Date: 2024-11-04 DOI: 10.1097/MOP.0000000000001415
Jeffrey I Campbell, Ana Poblacion, Richard Sheward
{"title":"Linking household members and defining relational networks using routine health data.","authors":"Jeffrey I Campbell, Ana Poblacion, Richard Sheward","doi":"10.1097/MOP.0000000000001415","DOIUrl":"10.1097/MOP.0000000000001415","url":null,"abstract":"<p><strong>Purpose of review: </strong>The growth of rich electronic health record (EHR) data and large health databases has introduced new opportunities to link individuals together into households and relational networks. These 'linked relational networks' hold promise for providing family-level care and studying intergenerational epidemiology and clinical outcomes. However, as linked relational networks become more commonly available in EHRs and research databases, it is critical to understand their challenges and limitations.</p><p><strong>Recent findings: </strong>Matching algorithms are being used to create linked relational networks in EHR and health databases. Clinically, these algorithms have been most useful to provide dyadic maternal-newborn care. In research, studies using these algorithms investigate topics ranging from the pharmacoepidemiology of parental drug exposure on childhood health outcomes, to heritability of chronic conditions, to associations between parental and child healthcare access and service delivery. However, ethical and technical challenges continue to limit use of these algorithms. There is also a critical research gap in the external validity of these matching algorithms.</p><p><strong>Summary: </strong>Linked relational networks are in widespread use in pediatric clinical care and research. More research is needed to understand the scope, limitations, and biases inherent in existing matching strategies.</p>","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"27-33"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11659028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the potential role of financial interventions to improve the health of families impacted by incarceration. 探索金融干预措施在改善受监禁影响家庭的健康状况方面的潜在作用。
IF 2.2 3区 医学
Current opinion in pediatrics Pub Date : 2025-02-01 Epub Date: 2024-11-02 DOI: 10.1097/MOP.0000000000001413
Destiny G Tolliver, Benjamin Howell, Sarah Blanton, Emily A Wang
{"title":"Exploring the potential role of financial interventions to improve the health of families impacted by incarceration.","authors":"Destiny G Tolliver, Benjamin Howell, Sarah Blanton, Emily A Wang","doi":"10.1097/MOP.0000000000001413","DOIUrl":"10.1097/MOP.0000000000001413","url":null,"abstract":"<p><strong>Purpose of review: </strong>To summarize the impact of financial hardship on children whose parents have been incarcerated, describe both existing cash transfer and guaranteed income programs, and highlight their impact on child and family well being.</p><p><strong>Recent findings: </strong>Emerging data on guaranteed income programs for formerly incarcerated adults indicates that the funds improve recipient health and legal system outcomes and allow participants to spend funds on stabilizing themselves and their families. Guaranteed income programs in the broader population similarly highlight the use of funds to support families' basic needs and improved parent-child relationships, but more data are needed to understand the impact on child health and well being among families impacted by the criminal legal system.</p><p><strong>Summary: </strong>Over 5 million children experience parental incarceration, which directly contributes to financial hardship and subsequent negative health outcomes. Cash transfers may assist these families, but policies and administrative burdens limit the ability of existing programs to fully address financial hardship. Guaranteed income programs may therefore serve a unique role in supporting the financial needs of families impacted by incarceration. More longitudinal data focusing on child health outcomes are necessary to fully understand the impact of guaranteed income of children and families impacted by parental incarceration.</p>","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"34-39"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What's up with patella alta? 上髌骨怎么了?
IF 2.2 3区 医学
Current opinion in pediatrics Pub Date : 2025-02-01 Epub Date: 2024-11-29 DOI: 10.1097/MOP.0000000000001428
Ruth H Jones, Emilie Lijesen, Daniel W Green
{"title":"What's up with patella alta?","authors":"Ruth H Jones, Emilie Lijesen, Daniel W Green","doi":"10.1097/MOP.0000000000001428","DOIUrl":"https://doi.org/10.1097/MOP.0000000000001428","url":null,"abstract":"<p><strong>Purpose of review: </strong>Patella alta, which describes an abnormally proximally positioned patella, has become of particular interest as it has been identified as a potential factor in patellofemoral instability (PFI) and other common pediatric orthopedic conditions. The purpose of this review is to describe the condition, measuring techniques, and its association with pediatric orthopedic conditions, and to evaluate methods of correction of patella alta.</p><p><strong>Recent findings: </strong>Recent literature has explored the etiology of patella alta by investigating patellar height as age increases, with inconclusive findings as to whether the condition is congenital or acquired over time. Additionally, patella alta has been identified to be associated with several pediatric orthopedic conditions, including PFI, anterior knee pain, and cerebral palsy. As such, methods of correction for patella alta, including medial patellofemoral ligament reconstruction (MPFLR), tibial tubercle distalization, and patella tendon imbrication, have been studied.</p><p><strong>Summary: </strong>Patella alta, defined by an abnormally high patellar height, is associated with patellofemoral instability, anterior knee pain, and cerebral palsy. Various indices have been developed to measure and define patellar height, including the Caton-Deschamps Index and Koshino-Sugimoto Index which are applicable to a pediatric population. Treatments include isolated or concomitant MPFLR, distalizing tibial tubercle osteotomy, and patella tendon imbrication, which have shown success in reducing patellar height and improving patella alta, though risks for complications do exist.</p>","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":"37 1","pages":"82-87"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142851923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cozen's phenomenon. 欺骗的现象。
IF 2.2 3区 医学
Current opinion in pediatrics Pub Date : 2025-02-01 Epub Date: 2024-11-25 DOI: 10.1097/MOP.0000000000001425
Matias Sepúlveda, Macarena Ulloa, Estefanía Birrer
{"title":"Cozen's phenomenon.","authors":"Matias Sepúlveda, Macarena Ulloa, Estefanía Birrer","doi":"10.1097/MOP.0000000000001425","DOIUrl":"https://doi.org/10.1097/MOP.0000000000001425","url":null,"abstract":"<p><strong>Purpose of review: </strong>The purpose of this review is to describe the current trends in the treatment of Cozen's phenomenon and evaluate if there are changes in the treatment paradigm due to the advent of implant-mediated guided growth.</p><p><strong>Recent findings: </strong>Current literature emphasizes the need for early recognition of Cozen's phenomenon (tibia valgus), with a high incidence associated with proximal tibia fractures. There are cases with late onset progression of the valgus deformity, which can be easily treated with implant-mediated guided growth.</p><p><strong>Summary: </strong>Clinical observation continues to be the current standard of treatment for this phenomenon. An average surveillance time of 2 years postfracture is recommended to observe for valgus deformity of the tibia. During this period, implant-mediated guided growth may be utilized to correct tibial deformity, which is an easier and safer solution than tibial osteotomy.</p>","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":"37 1","pages":"94-98"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of the etiology of childhood cancer and future directions. 儿童癌症的病因及未来发展方向。
IF 2.2 3区 医学
Current opinion in pediatrics Pub Date : 2025-02-01 Epub Date: 2024-12-02 DOI: 10.1097/MOP.0000000000001419
Thanh T Hoang, Michael E Scheurer, Philip J Lupo
{"title":"Overview of the etiology of childhood cancer and future directions.","authors":"Thanh T Hoang, Michael E Scheurer, Philip J Lupo","doi":"10.1097/MOP.0000000000001419","DOIUrl":"https://doi.org/10.1097/MOP.0000000000001419","url":null,"abstract":"<p><strong>Purpose of review: </strong>We provide an overview of the etiology of childhood cancer, the state of the literature, and highlight some opportunities for future research, including technological advancements that could be applied to etiologic studies of childhood cancer to accelerate our understanding.</p><p><strong>Recent findings: </strong>Risk factors of childhood cancer were summarized based on demographics and perinatal factors, environmental risk factors, and genetic risk factors. Overall, demographics and perinatal factors are the most well studied in relation to childhood cancer. While environmental risk factors have been implicated, more work is needed to pinpoint specific exposures, identify window(s) of susceptibility, and understand mechanisms. With genome-wide association studies (GWAS), genetic risk factors of eight childhood cancers have emerged, and opportunities remain to conduct GWAS for other cancer types and determine whether risk variants are inherited or de novo. Technological advancements that can shed light into the susceptibility of childhood cancer include metabolomics, using primary teeth as an exposure matrix, and long-read sequencing.</p><p><strong>Summary: </strong>The development of childhood cancer remains largely not well understood. Collaboration to increase sample size to conduct analyses by histology and/or molecular subtype and application of novel technologies will accelerate our understanding of childhood cancer.</p>","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":"37 1","pages":"59-66"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Updates on neurologic manifestations of mitochondrial disease. 线粒体疾病神经系统表现的最新进展。
IF 2.2 3区 医学
Current opinion in pediatrics Pub Date : 2025-02-01 Epub Date: 2024-12-06 DOI: 10.1097/MOP.0000000000001418
Britta Kuusik, Divakar S Mithal
{"title":"Updates on neurologic manifestations of mitochondrial disease.","authors":"Britta Kuusik, Divakar S Mithal","doi":"10.1097/MOP.0000000000001418","DOIUrl":"https://doi.org/10.1097/MOP.0000000000001418","url":null,"abstract":"<p><strong>Purpose of review: </strong>Primary mitochondrial disease (PMD) is diverse both genetically and phenotypically. Neurologic manifestations are present at a high rate and often pose complications for providers. The review will discuss common manifestations and how advances in genetic testing have broadened understanding of PMDs.</p><p><strong>Recent findings: </strong>Across all areas of PMD research, genetic advancements are notable both for mitochondrial and nuclear DNA.</p><p><strong>Summary: </strong>Global understanding of PMDs is driving deeper and broader research. Neurologic manifestations primarily include neuromuscular disease, epilepsy, stroke-like episodes and neurodegeneration, and advances in all areas have benefitted from global reporting of genetic studies.</p>","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":"37 1","pages":"107-111"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances in pediatric oncology through collaborations. 通过合作在儿科肿瘤学方面取得进展。
IF 2.2 3区 医学
Current opinion in pediatrics Pub Date : 2025-02-01 Epub Date: 2024-12-20 DOI: 10.1097/MOP.0000000000001429
Brigitte C Widemann
{"title":"Advances in pediatric oncology through collaborations.","authors":"Brigitte C Widemann","doi":"10.1097/MOP.0000000000001429","DOIUrl":"https://doi.org/10.1097/MOP.0000000000001429","url":null,"abstract":"","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":"37 1","pages":"40-41"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do new quality measures for social risk screening 'measure up'? 社会风险筛查的新质量标准是否 "达标"?
IF 2.2 3区 医学
Current opinion in pediatrics Pub Date : 2025-02-01 Epub Date: 2024-11-02 DOI: 10.1097/MOP.0000000000001414
Kameswari Potharaju, Laura M Gottlieb, Matthew Pantell, Danielle Hessler Jones
{"title":"Do new quality measures for social risk screening 'measure up'?","authors":"Kameswari Potharaju, Laura M Gottlieb, Matthew Pantell, Danielle Hessler Jones","doi":"10.1097/MOP.0000000000001414","DOIUrl":"10.1097/MOP.0000000000001414","url":null,"abstract":"<p><strong>Purpose of review: </strong>New social risk screening standards and quality metrics reward or penalize healthcare delivery organizations for social risk screening. After summarizing the recent literature on social risk screening in pediatric healthcare settings we consider how this evidence - and persistent evidence gaps - might inform future standards development.</p><p><strong>Recent findings: </strong>Reported social risk screening rates, measures, and modality differ greatly across recent work. Although many caregivers report acceptability of screening, experiences and expectations around effective follow-up vary. Likewise, although most frontline clinical providers find screening acceptable, they report significant implementation challenges related to time constraints, insufficient workforce, and availability of social services. Qualitative findings suggest opportunities to improve screening implementation. Literature examining the impacts of screening continues to focus on immediate posited impacts of assistance programs; few studies assess health outcomes.</p><p><strong>Summary: </strong>The existing literature does not clearly indicate whether, when, how, or for whom social risk screening standards focused on screening quantity will contribute to child health or health equity. Informed by studies on patient experience, quality measures focused on screening quantity (e.g. how many individuals are screened) should be paired with efforts to improve screening quality (i.e. patient/caregiver screening experience) as well as social and health outcomes.</p>","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"7-12"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142603543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
National virtual tumor boards to inform the management of children with rare cancers. 国家虚拟肿瘤委员会告知管理与罕见癌症的儿童。
IF 2.2 3区 医学
Current opinion in pediatrics Pub Date : 2025-02-01 Epub Date: 2024-11-28 DOI: 10.1097/MOP.0000000000001421
Shoba A Navai, Priya Mahajan, Rajkumar Venkatramani
{"title":"National virtual tumor boards to inform the management of children with rare cancers.","authors":"Shoba A Navai, Priya Mahajan, Rajkumar Venkatramani","doi":"10.1097/MOP.0000000000001421","DOIUrl":"https://doi.org/10.1097/MOP.0000000000001421","url":null,"abstract":"<p><strong>Purpose of review: </strong>Due to the infrequent nature of rare pediatric cancers, rigorously studied treatment algorithms are usually nonexistent, and experience with a given tumor may be limited at a single institution. Development of treatment plans for these populations often requires extensive literature review and outreach to experts at other institutions. National or international virtual tumor boards provide a streamlined, collaborative approach to discussing diagnosis and management of these patients through dissemination of collective experience and knowledge. This review highlights current virtual tumor boards for rare pediatric cancers and their benefit as a resource for patient care.</p><p><strong>Recent findings: </strong>Over the last several years, national virtual tumor boards sponsored by government and academic institutions and cancer foundations have expanded access of pediatric oncologists to rare tumor expertise and guidance. Recommendations from these tumor boards often have an impact on medical decision making, and some serve as a resource for enduring educational reference materials.</p><p><strong>Summary: </strong>National virtual tumor boards are a valuable resource to clinicians caring for patients with rare pediatric tumors. These conferences provide real-time management advice from peers and subject matter experts and provide essential educational content not easily accessible in other formats.</p>","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":"37 1","pages":"56-58"},"PeriodicalIF":2.2,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Updates in atypical hemolytic syndrome. 非典型溶血综合征的最新进展。
IF 2.2 3区 医学
Current opinion in pediatrics Pub Date : 2025-01-24 DOI: 10.1097/MOP.0000000000001435
Keri Drake, Jyothsna Gattineni
{"title":"Updates in atypical hemolytic syndrome.","authors":"Keri Drake, Jyothsna Gattineni","doi":"10.1097/MOP.0000000000001435","DOIUrl":"10.1097/MOP.0000000000001435","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review aims to summarize how scientific advances in complement biology have not only improved the diagnosis and management of aHUS but also continue to offer insights into the pathophysiology of complement-mediated disease that may be leveraged for future therapeutic developments.</p><p><strong>Recent findings: </strong>Updated information on the clinical and epidemiological features, pathophysiology, diagnosis, management, and potential for future therapeutic advancements in the treatment of aHUS are reviewed.</p><p><strong>Summary: </strong>aHUS is a rare but potentially life-threatening disease that requires prompt diagnosis and treatment as well as long-term management via a multidisciplinary team providing coordination of primary and specialty care as well as outreach and education for children and families affected by this life-long disease.</p>","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143064351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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