Cumhuriyet Science Journal最新文献

{"title":"Cross-Section Calculations of Medical Radioisotope 64Cu via some Proton, Neutron and Deuteron Reactions","authors":"GÜLÜMSER, Tuğçe\u0000 , KAPLAN, Abdullah\u0000 ","doi":"10.17776/csj.1290957","DOIUrl":"https://doi.org/10.17776/csj.1290957","url":null,"abstract":"The Copper-64 radioisotope, whose academic research continues on diagnostic and therapeutic use, was examined in this study. 64Cu radioisotope is unique among other Cu isotopes for medical usage due to its low positron energy, appropriate half-life, and short tissue penetration. In cases where experimental data are missing, cross-section calculations can be used, and the existence of the cross-section data may provide various advantages in managing time, cost, and efficiency. In this context, investigated detailed cross-section calculations of the 64Cu isotope. To this end, cross-sections acquired from various calculation codes were compared with the literature, and alternative production routes were investigated. Using the nuclear reaction codes TALYS and EMPIRE, cross-section data of the 64Cu isotope were obtained from the 64Ni(p,n)64Cu, 65Cu(p,n+p)64Cu, 68Zn(p,n+α)64Cu, 65Cu(n,2n)64Cu, 64Ni(d,2n)64Cu, and 63Cu(d,p)64Cu reactions with the equilibrium and pre-equilibrium models. The results were compared with the available literature data from the EXFOR database.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A New Nickel(II) Complex Derived From Bisthiocarbohydrazone: Synthesis, Characterization, Crystal Structure and Antioxidant Activity","authors":"KAYA, Yeliz\u0000 ","doi":"10.17776/csj.1248428","DOIUrl":"https://doi.org/10.17776/csj.1248428","url":null,"abstract":"A new complex with composition [Ni(L)(PPh3)] (PPh3 = triphenylphosphine) was obtained from the reaction of 1,5-bis(salicylidene)thiocarbohydrazone (L) with an equimolar amount of [NiCl2(PPh3)2]. The complex was identified by FT-IR, 1H NMR and UV-Vis spectroscopic methods and elemental analysis. The solid state structure of [Ni(L)(PPh3)] was established by X-ray diffraction analysis. It was determined that the complex, whose nickel center has a distorted square planar configuration, crystallizes in the monoclinic space group I2/c. Bisthiocarbohydrazone (L) binds to the nickel center through its phenolate O, azomethine N and thioenolate S atoms in a dianionic tridentate mode. The antioxidant capacity of L and Ni(II) complex was examined using the CUPRAC (cupric reducing antioxidant capacity) method. Also, the DPPH (1,1-Diphenyl-2-picrylhydrazyl) method was used to test free radical scavenging activity of the compounds. Antioxidant activity results showed that L exhibited better activity than Ni(II) complex.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Knitting Pattern of PP Mesh on the Flexural Properties of Heat-cured PMMA Denture Base Resin","authors":"YERLİYURT, Kaan\u0000 , EĞRİ, Sinan\u0000 ","doi":"10.17776/csj.1184249","DOIUrl":"https://doi.org/10.17776/csj.1184249","url":null,"abstract":"Heat-cured polymethyl methacrylate is (PMMA) is the most common denture base material and some mechanical properties such as flexural strength and impact resistance etc. may lead to fail, besides its excellent properties. Polypropylene (PP) hernia mesh is a commercially available medical textile used in surgical repair of different types of hernia. It was aimed to investigate the effect of two different knitting patterns of PP meshes on the flexural properties of the PMMA denture base resin when they are used as reinforcement and compare with glass fiber mesh reinforced and no mesh used resins. Knitting patterns of the PP mesh structures were hexagonal honeycomb pattern and square pattern and these were used as single or double layer as reinforcement. 6 groups were established in the study: control group with no mesh and 5 reinforced groups with meshes (glass fiber mesh, single layer honeycomb patterned PP mesh, double layer honeycomb patterned PP mesh, single layer square patterned PP mesh, double layer square patterned PP mesh). A total of 60 samples with the dimensions of 65x10x3 mm, n=10 in each group were fabricated. The flexural strength, maximum deformation, and flexural modulus were determined by three-point bending test. Fracture surfaces were evaluated by scanning electron microscopy. The obtained data were statistically analyzed by two-way ANOVA test with Bonferroni corrections. The single layer square patterned PP mesh group exhibited the highest (76.67 ± 7.64 MPa), and the control group showed the lowest (63.49 ± 7.18 MPa) flexural strength values. The single layer glass fiber mesh group showed the highest (7.13 ± 0.55 mm) and the control group showed the lowest (4.72 ± 0.81 mm) maximum deformation values. The single layer glass fiber mesh group exhibited the highest (2131.87 ± 205.76 MPa), and the control group exhibited the lowest (1582.26 ± 98.63 MPa) flexural modulus values. Significant increase in flexural strength was observed in all polypropylene mesh-reinforced groups compared to the control group except double layer honeycomb patterned PP mesh group (p < 0.05). Using PP fiber mesh for reinforcement provide a very favorable aesthetic view and PP fiber mesh is concluded to be a promising material for reinforcement of heat-cured PMMA denture base resins.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical Study of Clopidogrel and its Determination in Pharmaceutical Preparations Using Square Wave Voltammetry","authors":"YILMAZ, Bilal\u0000 , YILMAZ, Semih\u0000 ","doi":"10.17776/csj.1282586","DOIUrl":"https://doi.org/10.17776/csj.1282586","url":null,"abstract":"In the present study, the electroanalytical behaviour of clopidogrel was investigated by cyclic voltammetry method. The procedure was based on clopidogrel being electrochemically oxidized at a platinum electrode in nonaqueous solutions. At 1.93 V, the oxidation peak was noted. It was discovered that clopidogrel's oxidation was diffusion-controlled. Additionally, a quick and easy SWV approach was developed and validated in this work to determine clopidogrel in pharmaceutical preparations. At concentrations between 5 and 50 µg/mL, the calibration curve was linear. The precision was given by relative standard deviation and was less than 2.73%. Accuracy was given with relative error and did not exceed 3.89%. In pharmaceutical preparations, clopidogrel had an average recovery of 100.1%. Under the chosen experimental conditions, no interference was found. The suggested method is extremely accurate and precise. Therefore, the method is applicable to the measurement of clopidogrel in pharmaceutical formulations.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of New Ostrowski’s Type Inequalities By Using Multistep Linear Kernel","authors":"QAYYUM, Yasır\u0000 , ALİ, Haider\u0000 , RASOOL, Faiz\u0000 , QAYYUM, Ather\u0000 ","doi":"10.17776/csj.1145020","DOIUrl":"https://doi.org/10.17776/csj.1145020","url":null,"abstract":"In this paper, we construct a generalisation of Ostrowski’s type inequalities with the help of new identity. By using this identity, we construct further results for ģ^'∈L^1 [c ̇,d ̆ ],ģ^'∈L^2 [c ̇,d ̆ ],ģ^''∈L^2 [c ̇,d ̆ ]. To prove our main and related results, we utilized some famous inequalities such as Gruss-inequality, Diaz-Mıtcaf’s inequality and Cauchy’s inequality. To prove our main results, we used a new multistep kernel (9-step linear kernel). Some related results are also discussed. In the end, we apply our results to numerical integration also.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bayesian Analysis for the Modified Frechet–Exponential Distribution with Covid-19 Application","authors":"AKDAM, Neriman\u0000 ","doi":"10.17776/csj.1320712","DOIUrl":"https://doi.org/10.17776/csj.1320712","url":null,"abstract":"In this manuscript, the maximum likelihood estimators and Bayes estimators for the parameters of the modified Frechet–exponential distribution. Because the Bayes estimators cannot be obtained in closed forms, the approximate Bayes estimators are computed using the idea of Lindley’s approximation method under squared-error loss function. Then, the approximate Bayes estimates are compared with the maximum likelihood estimates in terms of mean square error and bias values using Monte Carlo simulation. Finally, real data sets belonging to COVID-19 death cases in Europe and China to are used to demonstrate the emprical results belonging to the approximate Bayes estimates, the maximum likelihood estimates.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135133273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"On Directed Length Ratios in the Lorentz-Minkowski Plane","authors":"Abdulaziz Açikgöz","doi":"10.17776/csj.1133780","DOIUrl":"https://doi.org/10.17776/csj.1133780","url":null,"abstract":"The linear structure of the Lorentz-Minkowski plane is almost the same as Euclidean plane. But, there is one different aspect. These planes have different distance functions. So, it can be interesting to study the Lorentz analogues of topics that include the distance concept in the Euclidean plane. Thus, in this study, we show that the relationship between Euclidean and Lorentz distances is given depending on the slope of the line segment. Following, we investigate Lorentz analogues of Thales’ theorem, Angle Bisector theorems, Menelaus’ theorem and Ceva’s theorem.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139334997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parametric Extension of a Certain Family of Summation-Integral Type Operators","authors":"Nadire Fulda Odabaşi, I. Yüksel","doi":"10.17776/csj.1173496","DOIUrl":"https://doi.org/10.17776/csj.1173496","url":null,"abstract":"In this paper, we introduce a parametric extension of a certain family of summation-integral type operators on the interval [0,∞). Firstly, we obtain test functions and central moments. Secondly, we investigate weighted approximation properties for these operators and estimate the rate of convergence. Then, we give a pointwise approximation for the Peetre K-functional and functions of the Lipschitz class. Moreover, we demonstrate Voronovskaja type theorem for the operators. Finally, the convergence properties of operators to some functions are illustrated by graphics.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45106899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, Characterization and in vitro Simulations of nano-HAP/GO Composite Drug Delivery System Produced by Hydrothermal Methods Loaded with Paclitaxel","authors":"F. Çiftçi","doi":"10.17776/csj.1258573","DOIUrl":"https://doi.org/10.17776/csj.1258573","url":null,"abstract":"In this study, it was aimed to develop a nano drug system that can be used in passive targeting in pancreatic cancer treatment. Hydroxyapatite nanocrystals (n-HAP) produced by hydrothermal process and graphene oxide (GO) produced by hummers method were used to increase the carrier capacity of the nano drug system and to activate the drug release kinetics and drug loading capacity. Analyses performed for nanocomposite drug carrier systems; FT-IR, XRD, TGA, BET analysis, Zeta potential, TEM and SEM. Paclitaxel (PTX), a chemotherapeutic drug used in the treatment of pancreatic cancer, was loaded into HAP nanocrystals (PTX- loaded n-HAP) and its activity on pancreatic cancer cells was investigated. When PTX was 1 and 2 mg, Encapsulation Efficiency (EE) and Drug Loading Content (LC) were 79.17-72.24% and 80.01-80.27%, respectively, for H-n-HAP crystal structure only, while EE and LC were 88.57-81.57% and 90.84-110.57%, respectively, when H-n-HAP crystal structure was loaded with 1 and 2 mg PTX together with GO. Here, it was observed PTX release profiles are according to the Hixson model. According to Fick's law, release profile was observed with values of k=1.89, n=0.21, SSD=0.04, R2=0.997, FIC=2.03, SD=0.004. In cell culture studies, as GO nanomaterials were loaded into H-n-HAP nanocrystal structure, the effect of PTX drug on pancreatic cancer increased and the viability of cancer cells decreased. It can be concluded that H-n-HAP/GO/PTX nanocomposite structure kills more pancreatic cancer cells with synergistic effect.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43096258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Intersection of Two Ruled Surfaces Corresponding to Spherical Indicatrix Curves on the Unit Dual Sphere","authors":"Yunus Öztemi̇r, M. Çalişkan","doi":"10.17776/csj.1197746","DOIUrl":"https://doi.org/10.17776/csj.1197746","url":null,"abstract":"In this study, we first investigate the intersection of two different ruled surfaces in R^3 for two different tangential spherical indicatrix curves on DS^2 using the E. Study mapping. The conditions for the intersection of these ruled surfaces in R^3 are expressed by theorems with bivariate functions. Secondly, considering two different principal normal spherical indicatrix curves on DS^2, we examine the intersection of two different ruled surfaces in R^3 by using E. Study mapping. Similarly, the conditions for the intersection of these ruled surfaces in R^3 are indicated by theorems with bivariate functions. Thirdly, using E. Study mapping, we explore the intersection of two different ruled surfaces in R^3 by considering two different binormal spherical indicatrix curves on DS^2. Likewise, the conditions for the intersection of these ruled surfaces in R^3 are denoted by theorems with bivariate functions. Fourthly, considering two different pole spherical indicatrix curves on DS^2, we study the intersection of two different ruled surfaces in R^3 by using E. Study mapping. In the same way, the conditions for the intersection of these ruled surfaces in R^3 are specified by theorems with bivariate functions. Finally, we provide some examples that support the main results.","PeriodicalId":10906,"journal":{"name":"Cumhuriyet Science Journal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49112016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}