Current Obesity Reports最新文献_第6页

Correction: The Effectiveness of eHealth Interventions for Weight Loss and Weight Loss Maintenance in Adults with Overweight or Obesity: A Systematic Review of Systematic Reviews. 更正：电子健康干预对超重或肥胖成年人减肥和维持减肥的有效性：系统评价的系统评价。

IF 8.8 2区医学

Current Obesity Reports Pub Date : 2023-12-01 DOI: 10.1007/s13679-023-00530-3

Sakris K E Kupila, Anu Joki, Laura-U Suojanen, Kirsi H Pietiläinen

引用次数: 0

Update on the Obesity Epidemic: After the Sudden Rise, Is the Upward Trajectory Beginning to Flatten? 肥胖流行病的最新消息：邪恶帝国的急剧崛起真的在趋于平稳吗？

IF 8.8 2区医学

Current Obesity Reports Pub Date : 2023-12-01 Epub Date: 2023-10-02 DOI: 10.1007/s13679-023-00527-y

Chrysi Koliaki, Maria Dalamaga, Stavros Liatis

{"title":"Update on the Obesity Epidemic: After the Sudden Rise, Is the Upward Trajectory Beginning to Flatten?","authors":"Chrysi Koliaki, Maria Dalamaga, Stavros Liatis","doi":"10.1007/s13679-023-00527-y","DOIUrl":"10.1007/s13679-023-00527-y","url":null,"abstract":"Purpose of review: To provide an update on current obesity prevalence trends and summarize the available evidence suggesting a possible plateau or stabilization in obesity rates after the previous sudden global rise.Recent findings: The escalating global obesity epidemic represents one of the most serious public health challenges. There have been some indications that in high-income populations, the rate of obesity increase in adults has been stabilized after the decade 2000-2010, suggesting a possible plateau. Current evidence also suggests that obesity rates have been stabilized in children and adolescents of most economically advanced countries since 2000, which is possibly related to healthier dietary habits and increased levels of physical activity. On the other hand, there is a steady uninterrupted rise in low-income nations, and the universal trend is obesity escalation rather than slowdown, mainly driven by sharp increases in the obesity prevalence of low-income populations. Furthermore, an increasing number of high- and middle-income countries are currently experiencing an epidemic of severe obesity. In high-income populations, severe obesity is expected to double its prevalence from 10 to 20% between 2020 and 2035, posing an enormous threat for healthcare systems. Even if transiently stabilized, the obesity prevalence remains globally at unacceptably high levels, and there is no guarantee that the current stability (if any) will be maintained for long. In this review, we explore the underlying drivers of the global obesity epidemic; we provide possible explanations for the reported slowdown of the obesity rates in some countries; and we overall take a critical perspective on the obesity plateau hypothesis, emphasizing the urgent need for immediate effective actions at population and regional level in order to halt the alarming obesity escalation and its serious health risks.","PeriodicalId":10846,"journal":{"name":"Current Obesity Reports","volume":null,"pages":null},"PeriodicalIF":8.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41105740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Upstream Determinants of Overweight and Obesity in Europe. 欧洲超重和肥胖的上游决定因素。

IF 8.8 2区医学

Current Obesity Reports Pub Date : 2023-12-01 Epub Date: 2023-08-18 DOI: 10.1007/s13679-023-00524-1

Stefanie Vandevijvere, Robby De Pauw, Sanne Djojosoeparto, Vanessa Gorasso, Leonor Guariguata, Anne Lene Løvhaug, Melissa Mialon, Iris Van Dam, Peter von Philipsborn

{"title":"Upstream Determinants of Overweight and Obesity in Europe.","authors":"Stefanie Vandevijvere, Robby De Pauw, Sanne Djojosoeparto, Vanessa Gorasso, Leonor Guariguata, Anne Lene Løvhaug, Melissa Mialon, Iris Van Dam, Peter von Philipsborn","doi":"10.1007/s13679-023-00524-1","DOIUrl":"10.1007/s13679-023-00524-1","url":null,"abstract":"Purpose of review: To review the upstream determinants of overweight and obesity in Europe, including food and built environments, and political, commercial, and socioeconomic determinants.Recent findings: Overweight and obesity affect 60% of European adults, and one in three children, and are more common in individuals with low compared to high socioeconomic position (SEP). Individuals in low SEP groups are more exposed to unhealthy built and food environments, including higher exposure to unhealthy food marketing. Industries influencing the food system have much economic power, resulting in ignoring or silencing the role of ultra-processed foods and commercial practices in weight gain. Overall, effective policies to address overweight and obesity have been insufficiently implemented by governments. To accelerate implementation, strengthened political commitment is essential. Policies must also focus on the upstream, structural, and systemic drivers of overweight and obesity; be comprehensive; and target socioeconomic inequalities in diets and physical activity.","PeriodicalId":10846,"journal":{"name":"Current Obesity Reports","volume":null,"pages":null},"PeriodicalIF":8.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10397290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetics and Epigenetics in Obesity: What Do We Know so Far? 肥胖的遗传学和表观遗传学：到目前为止我们知道什么？

IF 8.8 2区医学

Current Obesity Reports Pub Date : 2023-12-01 Epub Date: 2023-10-11 DOI: 10.1007/s13679-023-00526-z

Maria Keller, Stina Ingrid Alice Svensson, Kerstin Rohde-Zimmermann, Peter Kovacs, Yvonne Böttcher

{"title":"Genetics and Epigenetics in Obesity: What Do We Know so Far?","authors":"Maria Keller, Stina Ingrid Alice Svensson, Kerstin Rohde-Zimmermann, Peter Kovacs, Yvonne Böttcher","doi":"10.1007/s13679-023-00526-z","DOIUrl":"10.1007/s13679-023-00526-z","url":null,"abstract":"Purpose of review: Enormous progress has been made in understanding the genetic architecture of obesity and the correlation of epigenetic marks with obesity and related traits. This review highlights current research and its challenges in genetics and epigenetics of obesity.Recent findings: Recent progress in genetics of polygenic traits, particularly represented by genome-wide association studies, led to the discovery of hundreds of genetic variants associated with obesity, which allows constructing polygenic risk scores (PGS). In addition, epigenome-wide association studies helped identifying novel targets and methylation sites being important in the pathophysiology of obesity and which are essential for the generation of methylation risk scores (MRS). Despite their great potential for predicting the individual risk for obesity, the use of PGS and MRS remains challenging. Future research will likely discover more loci being involved in obesity, which will contribute to better understanding of the complex etiology of human obesity. The ultimate goal from a clinical perspective will be generating highly robust and accurate prediction scores allowing clinicians to predict obesity as well as individual responses to body weight loss-specific life-style interventions.","PeriodicalId":10846,"journal":{"name":"Current Obesity Reports","volume":null,"pages":null},"PeriodicalIF":8.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41194119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Lifestyle Modification with Second-Generation Anti-obesity Medications: Comparisons, Questions, and Clinical Opportunities. 生活方式改变与第二代抗肥胖药物的作用:比较、问题和临床机会。

IF 8.8 2区医学

Current Obesity Reports Pub Date : 2023-12-01 Epub Date: 2023-12-02 DOI: 10.1007/s13679-023-00534-z

Thomas A Wadden, Ariana M Chao, Molly Moore, Jena S Tronieri, Adam Gilden, Anastassia Amaro, Sharon Leonard, John M Jakicic

{"title":"The Role of Lifestyle Modification with Second-Generation Anti-obesity Medications: Comparisons, Questions, and Clinical Opportunities.","authors":"Thomas A Wadden, Ariana M Chao, Molly Moore, Jena S Tronieri, Adam Gilden, Anastassia Amaro, Sharon Leonard, John M Jakicic","doi":"10.1007/s13679-023-00534-z","DOIUrl":"10.1007/s13679-023-00534-z","url":null,"abstract":"Purpose of review: This review examines lifestyle modification for obesity management with the goal of identifying treatment components that could support the use of a new generation of anti-obesity medications (AOMs).Recent findings: Semaglutide reliably reduces baseline body weight by approximately 15% at 68 weeks, in contrast to 5-10% for lifestyle modification. Tirzepatide induces mean losses as great as 20.9%. Both medications reduce energy intake by markedly enhancing satiation and decreasing hunger, and they appear to lessen the need for traditional cognitive and behavioral strategies (e.g., monitoring food intake) to achieve calorie restriction. Little, however, is known about whether patients who lose weight with these AOMs adopt healthy diet and activity patterns needed to optimize body composition, cardiometabolic health, and quality of life. When used with the new AOMs, the focus of lifestyle modification is likely to change from inducing weight loss (through calorie restriction) to facilitating patients' adoption of dietary and activity patterns that will promote optimal changes in body composition and overall health.","PeriodicalId":10846,"journal":{"name":"Current Obesity Reports","volume":null,"pages":null},"PeriodicalIF":8.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138470078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revisiting Resting Metabolic Rate: What is the Relation to Weight Fluctuations? 重新审视静息代谢率：与体重波动有什么关系？

IF 8.8 2区医学

Current Obesity Reports Pub Date : 2023-12-01 Epub Date: 2023-09-27 DOI: 10.1007/s13679-023-00528-x

Georgia Argyrakopoulou, Nefeli Fountouli, Maria Dalamaga, Alexander Kokkinos

{"title":"Revisiting Resting Metabolic Rate: What is the Relation to Weight Fluctuations?","authors":"Georgia Argyrakopoulou, Nefeli Fountouli, Maria Dalamaga, Alexander Kokkinos","doi":"10.1007/s13679-023-00528-x","DOIUrl":"10.1007/s13679-023-00528-x","url":null,"abstract":"Purpose of review: Despite the great progress in obesity-tackling strategies, a negative energy equilibrium between energy expenditure and energy intake remains the cornerstone in obesity management. The present review article aims to shed light on the complicated interrelations of resting metabolic rate to weight fluctuations.Recent findings: Energy expenditure depends on body composition and is highly affected by weight changes, exerting a significant role in subsequent weight regain and underlining the metabolic resistance that people with obesity face when dealing with weight maintenance. The main tissue involved in energy expenditure is fat-free mass, as opposed to fat mass, which exerts a substantially lower impact. Although people with obesity display higher energy expenditures than their lean counterparts, these decrease substantially in the setting of weight loss. Metabolic adaptation is the difference between measured and predicted RMR after weight loss, either via lifestyle modification or after obesity surgery. Plausible explanations for this include differences in body composition, with loss of fat-free mass playing a significant role. This becomes especially apparent in the setting of rapid and massive weight loss, as in the case of bariatric surgery. A better understanding of energy expenditure pathophysiology may aid in further enhancing weight loss and promoting weight maintenance in people with obesity.","PeriodicalId":10846,"journal":{"name":"Current Obesity Reports","volume":null,"pages":null},"PeriodicalIF":8.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41115873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pediatric Obesity Care via Telemedicine: Expanding the Path Forward-A Review. 通过远程医疗进行儿童肥胖护理：拓展前进道路——综述。

IF 8.8 2区医学

Current Obesity Reports Pub Date : 2023-12-01 Epub Date: 2023-11-08 DOI: 10.1007/s13679-023-00537-w

Valerie M O'Hara, Danielle Louder, Starr V Johnston, Kathrin Hastey, Nancy T Browne

引用次数: 0

Correction to: Update on the Obesity Epidemic: After the Sudden Rise, Is the Upward Trajectory Beginning to Flatten? 更正：肥胖流行的最新消息：在突然上升之后，向上的轨迹开始变平了吗？

IF 8.8 2区医学

Current Obesity Reports Pub Date : 2023-12-01 DOI: 10.1007/s13679-023-00533-0

Chrysi Koliaki, Maria Dalamaga, Stavros Liatis

引用次数: 0

Incomplete Data and Potential Risks of Drugs in People with Obesity. 肥胖患者用药的不完整数据和潜在风险。

IF 8.8 2区医学

Current Obesity Reports Pub Date : 2023-12-01 Epub Date: 2023-11-18 DOI: 10.1007/s13679-023-00532-1

Caroline M Apovian, Christopher D Bruno, Theodore K Kyle, Christina R Chow, David J Greenblatt

{"title":"Incomplete Data and Potential Risks of Drugs in People with Obesity.","authors":"Caroline M Apovian, Christopher D Bruno, Theodore K Kyle, Christina R Chow, David J Greenblatt","doi":"10.1007/s13679-023-00532-1","DOIUrl":"10.1007/s13679-023-00532-1","url":null,"abstract":"Purpose of review: To provide examples of knowledge gaps in current pharmaceutical treatments for people with obesity and call for changes to regulatory and pharmaceutical clinical research requirements during the drug discovery and development process.Recent findings: Treatment of obesity and its comorbidities often require the use of prescription drugs, many of which have not been fully evaluated in people with obesity. Despite a growing body of research on this topic, the impact of obesity on the pharmacokinetics and pharmacodynamics of drugs is often under-studied by drug sponsors and regulators, and subsequently underappreciated by clinicians and caretakers. There are currently multiple opportunities for pharmaceuticals to include dosing information specifically for patients with obesity in order to ensure safety and efficacy of drugs in this population. Additionally, there are serious gaps between what is known about the effects of obesity on drug disposition and the current use of drugs according to drug prescribing information and clinical practice. There is currently no requirement to test drugs in people with obesity during the drug approval process, even when preliminary data suggests there may be altered kinetics in this population. The lack of information on the safe and effective use of drugs in people with obesity may be contributing to poorer health outcomes in this population.","PeriodicalId":10846,"journal":{"name":"Current Obesity Reports","volume":null,"pages":null},"PeriodicalIF":8.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138046444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Systematic Review of the Bidirectional Association Between Consumption of Ultra-processed Food and Sleep Parameters Among Adults. 关于超加工食品摄入量与成年人睡眠参数之间双向关系的系统性综述。

IF 8.8 2区医学

Current Obesity Reports Pub Date : 2023-12-01 Epub Date: 2023-07-21 DOI: 10.1007/s13679-023-00512-5

Valentina A Andreeva, Jara Perez-Jimenez, Marie-Pierre St-Onge

{"title":"A Systematic Review of the Bidirectional Association Between Consumption of Ultra-processed Food and Sleep Parameters Among Adults.","authors":"Valentina A Andreeva, Jara Perez-Jimenez, Marie-Pierre St-Onge","doi":"10.1007/s13679-023-00512-5","DOIUrl":"10.1007/s13679-023-00512-5","url":null,"abstract":"Purpose of review: We summarized research on the bidirectional association between intake of ultra-processed food (UPF) and sleep.Recent findings: Sleep contributes to cardiometabolic health in part via food intake patterns. Restricting sleep increases intakes of high-carbohydrate/high-fat foods, a profile representative of UPF. This systematic review covers the association of UPF intake, as an exposure or an outcome, and sleep. UPF was defined as NOVA Group 4. MEDLINE and EMBASE were searched through April 2023 for epidemiological studies with general-population adult samples. Fifteen studies met the inclusion criteria; all were cross-sectional, published between 2016 and 2023, with samples from Brazil (n = 8), Spain (n = 2), Italy (n = 1), the UK (n = 1), Paraguay (n = 1), Iran (n = 1) and China (n = 1). Thirteen studies examined UPF intake as the exposure whereas two tested UPF intake as the outcome. UPF intakes were determined using food frequency questionnaires (73%) or 24-h recalls (27%). Two studies assessed sleep via accelerometry; the remaining studies relied on self-reports of sleep quality, duration, anxiety-induced insomnia, and napping, with 60% using a single question. The average methodological quality across the studies was deemed \"fair\". Six of the 13 studies that examined UPF consumption as the exposure revealed inverse associations with sleep outcomes in adjusted (n = 5) or bivariate (n = 1) analyses. Both studies addressing UPF consumption as the outcome and sleep as the exposure showed significant inverse associations. Evidence for UPF-sleep associations is accumulating, although sleep assessment limitations are apparent. This review can provide impetus for research using comprehensive and validated sleep measures and nudge policymakers towards refining dietary guidelines worldwide.","PeriodicalId":10846,"journal":{"name":"Current Obesity Reports","volume":null,"pages":null},"PeriodicalIF":8.8,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11165373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10205058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0