{"title":"Kombucha Tea: A Functional Beverage and All its Aspects.","authors":"Begum Onsun, Kadriye Toprak, Nevin Sanlier","doi":"10.1007/s13668-025-00658-9","DOIUrl":"10.1007/s13668-025-00658-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>The increasing interest in functional foods and beverages worldwide is driven by rising living standards, advancing technology, and heightened health awareness. Kombucha tea, a fermented beverage produced from sweetened tea and a symbiotic culture of bacteria and yeast (SCOBY), is a prominent example within this category. This review explores the definition, bioactive components, and health benefits of kombucha, emphasizing its potential roles as a functional beverage in the prevention and management of various diseases.</p><p><strong>Recent findings: </strong>The fermentation process of kombucha tea, typically lasting up to 14 days, results in the transformation of sugar into ethanol and acetic acid, contributing to its distinctive tangy flavor. Kombucha contains bioactive compounds such as organic acids, antioxidants, and probiotics, which are linked to potential health benefits including improved digestive health, enhanced immune function, and antioxidant activity. Recent advancements in sustainable production methods and innovative formulations have further contributed to the increasing popularity of this beverage. Kombucha tea, originating in Northeast China with a history of over 2,000 years, is increasingly recognized for its potential health-promoting effects. Its production through traditional fermentation methods combined with modern innovations underscores its value as a functional beverage with the potential to support health and well-being. This review assesses the roles of kombucha in maintaining human health, considering its use as a complementary strategy for the prevention and management of diseases due to the bioactive components it contains.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"69"},"PeriodicalIF":4.6,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12103323/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahdi Soroushianfar, Goli Asgari, Fatemeh Afzali, Atiyeh Falahat, Mohammad Soroush Mansoor Baghahi, Mohammad Javad Haratizadeh, Ghazaleh Khalili-Tanha, Elham Nazari
{"title":"Application of Bioinformatics and Machine Learning Tools in Food Safety.","authors":"Mahdi Soroushianfar, Goli Asgari, Fatemeh Afzali, Atiyeh Falahat, Mohammad Soroush Mansoor Baghahi, Mohammad Javad Haratizadeh, Ghazaleh Khalili-Tanha, Elham Nazari","doi":"10.1007/s13668-025-00657-w","DOIUrl":"10.1007/s13668-025-00657-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>Food safety is a fundamental challenge in public health and sustainable development, facing threats from microbial, chemical, and physical contamination. Innovative technologies improve our capacity to detect contamination early and prevent disease outbreaks, while also optimizing food production and distribution processes.</p><p><strong>Recent findings: </strong>This article discusses the role of new bioinformatics and machine learning technologies in promoting food safety and contamination control, along with various related articles in this field. By analyzing genetic and proteomic data, bioinformatics helps to quickly and accurately identify pathogens and sources of contamination. Machine learning, as a powerful tool for massive data processing, also can discover hidden patterns in the food production and distribution chain, which helps to improve risk prediction and control processes. By reviewing previous research and providing new solutions, this article emphasizes the role of these technologies in identifying, preventing, and improving decisions related to food safety. This study comprehensively shows how the integration of bioinformatics and machine learning can help improve food quality and safety and prevent foodborne disease outbreaks.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"67"},"PeriodicalIF":4.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144093135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Disha Naidu, K P Althaf Umar, K Muhsina, Sanu Augustine, Manish Kumar Jeengar, Kanthlal S K
{"title":"Zingiberaceae in Cardiovascular Health: A review of adipokine modulation and endothelial protection via adipocyte-endothelial crosstalk mechanism.","authors":"Disha Naidu, K P Althaf Umar, K Muhsina, Sanu Augustine, Manish Kumar Jeengar, Kanthlal S K","doi":"10.1007/s13668-025-00656-x","DOIUrl":"10.1007/s13668-025-00656-x","url":null,"abstract":"<p><strong>Purpose of the review: </strong>Although adipose tissue controls metabolism and protects vital organs, its importance to general health is being highlighted by the rise in type 2 diabetes and cardiovascular disease. Adipokines produced by adipose cells are essential regulators of metabolism, glucose homeostasis, and inflammatory response. It also protects vascular endothelial cells for its potential implications for cardiovascular protection. Understanding its intricate involvement in adipose tissue-endothelial communication is critical in developing targeted therapeutics to treat cardiovascular conditions linked with obesity and metabolic dysregulation. Spices from the Zingiberaceae family, such as cardamom, turmeric, and ginger, have anti-inflammatory and anti-oxidant properties that help reduce oxidative stress, vascular dysfunction, and adipocyte-endothelial crosstalk which are all linked to the etiology of CVD. Comprehensive molecular insights into how they modulate adipokine signalling, inflammatory pathways, and ROS-induced adipocyte-vascular interactions remain unexplored, demanding additional translational and clinical validation. With an emphasis on patients with obesity and metabolic dysregulation, the investigation aims to elucidate the mechanisms by which the spice as whole/bioactive constituents of the Zingiberaceae family may provide protection against CVD by integrating previous studies.</p><p><strong>Recent findings: </strong>Current research continues to support the use of spices from the Zingiberaceae family, such as ginger, turmeric, cardamom, and pepper, as potential therapeutic agents for addressing metabolic complications like obesity, type II diabetes, and CVDs. These natural remedies may modulate adipocyte-endothelial crosstalk and inflammation by modulating important signalling pathways such as AMPK, AKT, PPAR, and NF-κB..</p><p><strong>Conclusion: </strong>This review provides a complete summary of existing knowledge, opening the way for future research and prospective therapeutic applications of Zingiberaceae spices in cardiovascular health management.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"66"},"PeriodicalIF":4.6,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"New Approaches to the Treatment of Severe Obesity-Prehabilitation as the Key to Success.","authors":"Aleksandra Budny, Agata Janczy, Adriana Mika","doi":"10.1007/s13668-025-00652-1","DOIUrl":"https://doi.org/10.1007/s13668-025-00652-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>Bariatric surgery (BS) has emerged as a crucial and effective treatment for severe obesity (SO), providing significant and sustained weight loss and improving comorbidities. Optimizing perioperative careparticularly through structured prehabilitation is crucial for improving surgical outcomes and long-term weight management. This review examines the role of prehabilitation, nutrition, psychological support, physical activity, and pharmacologic treatment in improving the effectiveness of BS.</p><p><strong>Recent findings: </strong>Despite the benefits of prehabilitation, there are significant differences in the way it is implemented in different healthcare centers. Protocols vary widely in terms of duration, components and intensity, leading to inconsistencies in patient preparation and postoperative recovery. Many patients still do not receive multidisciplinary support from dietitians, psychologists or physiotherapists prior to surgery, which can affect long-term outcomes. Barriers to effective prehabilitation include a lack of standardized guidelines, insufficient healthcare resources and limited patient adherence due to lack of awareness, low motivation or logistical constraints. Despite its proven benefits, structured prehabilitation lasting at least 3-6 months is not available to all patients, as access remains unequal and suboptimal in many healthcare settings. Prehabilitation is an important but underutilized component of BS preparation. Standardizing protocols and ensuring multidisciplinary, patient-centered support are essential to maximizing surgical benefit. Overcoming barriers such as healthcare system limitations, patient motivation and knowledge gaps is critical to integrating prehabilitation into routine bariatric care. This review emphasizes the need for evidence-based, multimodal prehabilitation strategies to improve perioperative care and long-term outcomes for BS patients.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"64"},"PeriodicalIF":4.6,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zoe Memel, Stephanie L Gold, Michelle Pearlman, Alicia Muratore, Robert Martindale
{"title":"Impact of GLP- 1 Receptor Agonist Therapy in Patients High Risk for Sarcopenia.","authors":"Zoe Memel, Stephanie L Gold, Michelle Pearlman, Alicia Muratore, Robert Martindale","doi":"10.1007/s13668-025-00649-w","DOIUrl":"https://doi.org/10.1007/s13668-025-00649-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>Glucagon-like peptide- 1 receptor agonists (GLP- 1 RA) are a rapidly expanding class of medications used to treat many chronic diseases. This review explores factors that may contribute to accelerated muscle loss among higher-risk patient populations and describes tailored interventions to reduce the risk of accelerated sarcopenia and frailty.</p><p><strong>Recent findings: </strong>While GLP- 1 RA can result in total weight loss upwards of 25%, recent studies show that they can also lead to significant loss of lean body mass, reaching as high as 15-40% of total weight lost. This rapid and significant decline in muscle mass while taking GLP- 1 RA places certain patient populations already predisposed to sarcopenia at higher risk for muscle loss and adverse events. Currently, there is insufficient evidence delving into the impact of GLP- 1 RA on body composition among older adults, patients with chronic kidney disease, liver disease, and inflammatory bowel disease. However, research suggests that a high protein diet and resistance training may help prevent loss of muscle mass during GLP- 1 RA usage. A targeted and individualized nutrition and physical activity regimen should be instituted for each patient with a focus on optimizing protein intake and performing frequent resistance training in order to minimize loss of muscle mass while promoting the loss of fat mass. Future research should evaluate the impact of GLP- 1 RA on sarcopenia in high-risk patient populations.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"63"},"PeriodicalIF":4.6,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dietary Factors and Cognitive Function: with a Focus on Subjective Cognitive Decline.","authors":"Tian-Shin Yeh, Deborah Blacker, Walter C Willett","doi":"10.1007/s13668-025-00638-z","DOIUrl":"https://doi.org/10.1007/s13668-025-00638-z","url":null,"abstract":"<p><strong>Purpose of the review: </strong>Age-related cognitive decline is an important global challenge. Substantial evidence suggests that diet may prevent or delay cognitive aging. This narrative review examines recent literature on how dietary factors influence cognitive function, with a focus on subjective cognitive decline (SCD).</p><p><strong>Recent findings: </strong>Higher intakes of flavonoids, carotenoids, and plant-based protein were associated with lower odds of SCD. Berries, citrus fruits and juices, carotenoid-rich and green leafy vegetables, and beans/legumes were among the foods with the strongest inverse associations with SCD. Healthy dietary patterns, such as the Mediterranean and MIND diet, may be beneficial for maintaining subjective cognitive function. Healthy choice of diet may play a role in lowering the risk of late-life SCD.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"62"},"PeriodicalIF":4.6,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nutritional Approaches in Autism Spectrum Disorder: A Scoping Review.","authors":"Ebru Ozler, Nevin Sanlier","doi":"10.1007/s13668-025-00655-y","DOIUrl":"10.1007/s13668-025-00655-y","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review was conducted to discuss the etiology of autism in the light of current information, to draw attention to the fact that defects in different biological mechanisms cause autism, and to examine the effectiveness of dietary interventions and supplements in relieving ASD symptoms.</p><p><strong>Recent findings: </strong>Autism spectrum disorder (ASD) is an extremely heterogeneous condition characterized by delays in reciprocal social interaction and communication skills, stereotyped behaviors, and a narrowed range of interests and limited activities. Comorbid conditions such as cognitive impairment, epilepsy, psychiatric diseases, and behavioral symptoms such as impaired social communication, repetitive behaviors, lack of interest in the environment, nutritional disorders, gastrointestinal diseases and abnormal (dysbiotic) states, sleep disorders, and dysmorphism are frequently encountered in individuals with ASD. Although nutrition is one of the environmental factors affecting ASD, it can also be effective in alleviating the behavioral and gastrointestinal symptoms of ASD. Various dietary models (GFCF diet, low glycemic index diet, ketogenic diet, specific carbohydrate diet, Mediterranean diet, GAPS, Feingold, Candida body ecology, allergy elimination diets, etc.) and supplements (vitamin D, polyunsaturated fatty acids, probiotics and prebiotics, phytochemicals) can be used to alleviate symptoms in individuals with ASD. The effectiveness and reliability of dietary interventions in individuals with ASD are a matter of significant debate, and the evidence for these practices is limited. Furthermore, there is no consensus on establishing an ideal nutritional model for individuals with ASD.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"61"},"PeriodicalIF":4.6,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12011661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143987080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Inflammation Diet and the Association with Inflammatory Markers in Individuals with Obesity - A Systematic Scoping Review.","authors":"Bruna Moraes Isidoro, Mileni Vanti Beretta, Priscila Trindade Flores, Vinicius Moraes Bierhals, Carolina Carvalho Martins, Fernanda Michielin Busnello, Alessandra Peres","doi":"10.1007/s13668-025-00653-0","DOIUrl":"10.1007/s13668-025-00653-0","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review examines the relationship between diet-induced inflammation and inflammatory markers in obese individuals. Considering the chronic inflammatory state linked to obesity and its association with metabolic diseases, the review focuses on how dietary patterns, particularly pro- and anti-inflammatory patterns, impact inflammation.</p><p><strong>Recent findings: </strong>Recent studies suggest that pro-inflammatory diets, rich in processed and energy-dense foods, are associated with elevated levels of inflammatory markers, such as C-reactive protein and interleukin-6, in individuals with obesity. Using the Dietary Inflammatory Index (DII), research has found correlations between high DII scores and increased levels of inflammation. However, results regarding other biomarkers like TNF-alpha, leptin, and adiponectin are mixed. Adopting an anti-inflammatory diet - rich in fiber, omega-3 fatty acids, and polyphenols while low in processed foods and refined sugars -may reduce inflammation markers. However, the extent of these effects varies across studies, populations, and methods, highlighting the heterogeneity of the findings. Diet is a modifiable factor in managing obesity-related inflammation. While pro-inflammatory diets consistently elevate inflammatory biomarkers, anti-inflammatory diets show potential benefits but inconsistent results. The DII is a valuable tool, but further research is needed to clarify its role in managing inflammation and supporting long-term health, considering factors like physical activity and body composition.</p>","PeriodicalId":10844,"journal":{"name":"Current Nutrition Reports","volume":"14 1","pages":"60"},"PeriodicalIF":4.6,"publicationDate":"2025-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}