Critical Care Medicine最新文献

{"title":"Assessment of Tissue Perfusion Pressure in Patients With Septic Shock: Beyond Mean Arterial Pressure.","authors":"Carlos Sanchez E, Ahmed Taha, Yasser Tolba, Glenn Hernandez, Michael R Pinsky","doi":"10.1097/CCM.0000000000006805","DOIUrl":"10.1097/CCM.0000000000006805","url":null,"abstract":"<p><strong>Objectives: </strong>Optimization of macrohemodynamics is just the starting point in the management of hemodynamics in patients with septic shock. We describe the interaction between the various determinants of arterial pressure and tissue perfusion, how to optimize them and their estimations at the bedside. This is a concise definitive review of the assessment of tissue perfusion pressure (TPP) in patients with septic shock beyond just mean arterial pressure (MAP).</p><p><strong>Data sources: </strong>Original publications were retrieved through a PubMed and MEDLINE databases with search terms related to septic shock, arterial blood pressure, critical closing pressure (Pcc), mean systemic filling pressure (Pmsf), and TPP. Supporting evidence was also retrieved from PubMed and MEDLINE when indicated.</p><p><strong>Study selection: </strong>English-language systematic reviews, narrative reviews, meta-analyses, randomized clinical trials, and observational studies.</p><p><strong>Data extraction and data synthesis: </strong>Data from relevant publications were reviewed, selected, and summarized by the authors and applied as indicated.</p><p><strong>Conclusions: </strong>The relationship between arterial pressure and outcomes in septic shock is complex and heterogeneous. Focusing on critical parameters-such as TPP, the vascular waterfall, and individual treatment effects-enables a more personalized approach, focused on perfusion rather than pressure alone. Persistent hypoperfusion despite adequate macrocirculatory targets marks a pivotal moment when microcirculatory assessment becomes essential to guide therapy and avoid potentially harmful escalation of fluids or vasopressors. Bedside measurements of systolic arterial pressure, MAP, diastolic arterial pressure, Pcc, and Pmsf offer practical tools for monitoring and tailoring treatment. Future clinical trials are needed to validate these metrics and refine resuscitation strategies in septic shock.</p>","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends of Physical and Occupational Therapy Utilization in ICU Patients Undergoing Mechanical Ventilation in the United States: 2008-2021.","authors":"Joel Mintz, Mohammed Mustafa, Rose M Puthumana, Juan P Uribe, Christopher M Mallow, Hayley B Gershengorn","doi":"10.1097/CCM.0000000000006795","DOIUrl":"https://doi.org/10.1097/CCM.0000000000006795","url":null,"abstract":"<p><strong>Background: </strong>Physical and occupational therapy (PT/OT) during invasive mechanical ventilation (IMV) may improve outcomes, however, utilization patterns are understudied.</p><p><strong>Objectives: </strong>Determine trends over time and by hospital in PT/OT utilization.</p><p><strong>Design: </strong>Retrospective study.</p><p><strong>Setting: </strong>Premier Healthcare Database hospitals (2008-2021).</p><p><strong>Patients: </strong>Adults beginning IMV by hospitalization day 3 and receiving IMV continuously for 3-14 days.</p><p><strong>Interventions: </strong>None.</p><p><strong>Measurements and main results: </strong>The primary outcome was PT/OT usage within the first 3 days of IMV (early PT/OT). Cochran-Armitage tests were used to evaluate unadjusted trends across discharge years. A multilevel multivariable logistic regression model was then created with discharge hospital as a random effect and clinical, sociodemographic, and hospital characteristics as covariables. The median odds ratio (mOR) was calculated to quantify the association of discharge hospital with PT/OT utilization. Across 814 hospitals, 1,228,909 early IMV hospitalizations were identified. Of those, 118,662 (9.7%) had early PT/OT. Frequency of early PT/OT rose from 2008 to 2019 (8.5-10.8%; ptrend < 0.001) before declining in 2020 (9.5%) and 2021 (8.9%). Across hospitals, median early PT/OT usage was 5.4% (interquartile range, 2.9-11.0%). After multivariable adjustment, patients were increasingly more likely to get early PT/OT every year until 2016 (adjusted odds ratio [aOR] for 2016 vs. 2008, 1.52; 95% CI, 1.46-1.59). Use then remained relatively flat until 2020 when it began to decline (aOR for 2020, 1.23; 95% CI, 1.18-1.29 and aOR for 2021, 1.20; 95% CI, 1.15-1.26). The odds of receiving early PT/OT in higher use hospitals was nearly three-fold higher than in lower use hospitals (mOR, 2.82; 95% CI, 2.67-2.97).</p><p><strong>Conclusions: </strong>Early PT/OT usage rose during the early period, before declining significantly in 2020 and 2021. However, use in 2020 and 2021 remained higher than in 2008. Individual hospital of discharge was an important factor in determining who got PT/OT during IMV.</p>","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Vasopressor Utilization in Critically Ill Patients With Acute Traumatic Spinal Cord Injury: A Retrospective Cohort Study.","authors":"Mona Hashemaghaie, Tetsu Ohnuma, Ruba Sajdeya, Shreya Khandelwal, N David Yanez, Vijay Krishnamoorthy, Karthik Raghunathan, Michael J Devinney, Aparna Depuru, Miriam M Treggiari","doi":"10.1097/CCM.0000000000006791","DOIUrl":"https://doi.org/10.1097/CCM.0000000000006791","url":null,"abstract":"<p><strong>Objectives: </strong>Evidence regarding vasopressor support for acute spinal cord injury (SCI) is lacking. We report early vasopressor use and hospital outcomes in patients with SCI.</p><p><strong>Design: </strong>Propensity-score standardized mortality ratio-weighted retrospective cohort study.</p><p><strong>Setting: </strong>U.S. hospitals participating in the Premier Healthcare Database, 2016-2020.</p><p><strong>Patients: </strong>Adults 18 years old or older with acute traumatic SCI at T8 level or above who received vasopressors within 48 hours of hospitalization.</p><p><strong>Interventions: </strong>None.</p><p><strong>Measurements and main results: </strong>Of 3636 patients included (mean [sd] age, 56 [19]; 2757 [75%] males), 2055 (57%) received phenylephrine, 548 (15%) received norepinephrine, 110 (3%) received other single vasopressor, and 923 (25%) received multiple vasopressors. Baseline cervical SCIs, higher Injury Severity Scores, neurogenic shock, and mechanical ventilation were more likely with norepinephrine administration. The primary outcome was death/hospice/skilled nursing facility vs. home/inpatient care facility/rehabilitation facility. Compared with the phenylephrine group, the norepinephrine group was more likely to have a discharge disposition of death/hospice/or skilled nursing facility (odds ratio [OR], 1.50; 95% CI, 1.14-1.99), and adverse events, including urinary tract infections (OR, 1.66; 95% CI, 1.17-2.35), cardiac arrest (OR, 2.70; 95% CI, 1.74-4.19), acute kidney injury (OR, 1.91; 95% CI, 1.32-2.77), tracheostomy (OR, 1.39; 95% CI, 1.04-1.86), death (OR, 2.04; 95% CI, 1.42-2.93), and longer hospital length of stay (estimate, 3.68 d; 95% CI, 1.63-5.74 d). We observed no differences in pneumonia, thromboembolic events, or cerebrovascular accidents.</p><p><strong>Conclusions: </strong>Phenylephrine and norepinephrine were the most used vasopressors in SCI patients, with norepinephrine more frequently selected in patients with higher injury severity. While indication bias and residual confounding may explain our findings, these data raise the question whether phenylephrine and norepinephrine have different efficacy and safety profiles. Future research should focus on comparative trials of these two commonly prescribed agents.</p>","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Medical Burden and Capacity Changes With Clinical Outcomes Among Patients Without COVID-19 During the Pandemic: A Multicenter Retrospective Cohort Study.","authors":"Masaaki Sakuraya, Tomoyuki Sugimoto, Kazuya Kikutani, Chikashi Takeda, Daisuke Kasugai, Hiromu Okano, Yoshitaka Aoki, Hiroki Shimada, Daisuke Kawakami, Akira Hirata, Takushi Santanda, Masaki Nakane, Junji Kumasawa, Toko Fukushima, Keisuke Ota, Naoki Moriyama, Masatoshi Uchida, Hiromasa Irie, Kenzo Ishii, Keisuke Mataichi, Junji Shiotsuka, Kensuke Sugimoto, Naoya Kobayashi, Reiki Kumashiro, Yukiko Koyama, Nobuaki Shime","doi":"10.1097/CCM.0000000000006785","DOIUrl":"https://doi.org/10.1097/CCM.0000000000006785","url":null,"abstract":"<p><strong>Objectives: </strong>The spillover impact of the COVID-19 pandemic on patients without COVID-19 in ICUs should be assessed. We aimed to assess the association of ICUs' medical burden and capacity changes with clinical outcomes in such patients during the COVID-19 pandemic.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Setting: </strong>Twenty-three ICUs in Japan.</p><p><strong>Patients: </strong>Patients without COVID-19 in ICUs from January 2019 to February 2023.</p><p><strong>Interventions: </strong>None.</p><p><strong>Measurements and main results: </strong>These ICUs completed a web-based questionnaire on medical burden and capacity limitations in November 2023, and they were classified as having a limited capacity if their scores exceeded the median; otherwise, they were categorized as having a maintained capacity. The primary outcome was the standardized mortality ratio (SMR), calculated with the Acute Physiology and Chronic Health Evaluation III-j model, compared with the pre-pandemic level. Using individual-level patient data, a generalized linear Poisson mixed-effects model including an offset-time term was employed to assess the association of capacity limitation, the number of patients with COVID-19, and ICU bed occupancy on the day of admission, with hazard ratios for in-hospital death. Nine and fourteen ICUs had a limited capacity (25,568 patients) and a maintained capacity (45,068 patients), respectively. SMRs increased in four epidemic waves in the ICUs with a limited capacity but in only one wave in those with a maintained capacity. After adjustment, capacity limitation (hazard ratio, 1.19; 95% CI, 1.01-1.41; p = 0.04) and the number of patients with severe COVID-19 (per five patients; hazard ratio, 1.09; 95% CI, 1.03-1.16; p = 0.002) were associated with in-hospital mortality, but ICU bed occupancy was not.</p><p><strong>Conclusions: </strong>SMRs increased more frequently in ICUs with a limited capacity during the pandemic. Our findings emphasize the need for proactive strategies to mitigate medical burden and capacity limitations for future preparedness.</p>","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144689092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Consideration of Sociodemographics in Sepsis Risk Prediction: Implications and Next Steps.","authors":"Deepshikha C Ashana, William F Parker","doi":"10.1097/CCM.0000000000006777","DOIUrl":"https://doi.org/10.1097/CCM.0000000000006777","url":null,"abstract":"","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sex- and Age-Related Differences in Post-Burn Pathophysiology.","authors":"Diana Julia Tedesco, Maria Fernanda Hutter, Fadi Khalaf, Gregory R Pond, Marc G Jeschke","doi":"10.1097/CCM.0000000000006789","DOIUrl":"https://doi.org/10.1097/CCM.0000000000006789","url":null,"abstract":"<p><strong>Objectives: </strong>Sex and its effects on outcomes after burn are controversially discussed. In particular, the impact of sex on physiologic responses post-burn remains largely unknown. To bridge this knowledge gap, this study aimed to explore outcomes and the underlying pathophysiological responses in males and females across different age groups.</p><p><strong>Design: </strong>Cohort study.</p><p><strong>Setting: </strong>Tertiary burn center.</p><p><strong>Patients: </strong>Adult burn patients (≥ 18 yr) admitted with an acute burn injury.</p><p><strong>Interventions: </strong>None.</p><p><strong>Measurements and main results: </strong>We included all patients (≥ 18 yr) admitted with acute burn injuries between 2006 and 2021. Patients were stratified based on sex assigned at birth and age group: adult (< 60 yr) vs. older adult (≥ 60 yr). Clinical laboratory measures and inflammatory markers were compared throughout hospitalization between male and female burn patients within each age group. Outcomes included 30-day mortality, in-hospital complications, organ biomarkers, and inflammatory cytokine responses. A total of 2321 patients were included. Adult females experienced greater mortality (1% vs. 2%; p < 0.05) and increased skin graft loss (5% vs. 9%; p < 0.05) compared with their male counterparts. Furthermore, among adults, female sex was an independent predictor of mortality in a multivariate model (odds ratio, 3.6; 95% CI, 1.3-9.6; p < 0.05). Adult females showed acute decreases in pro-inflammatory cytokines (interferon-γ, interleukin [IL]-6, IL-1β, tumor necrosis factor-α; p < 0.05). Interestingly, no differences in mortality or complications were observed between older adult males and females. Older adult males and females also showed similar inflammatory responses and limited differences in organ function.</p><p><strong>Conclusions: </strong>In this large cohort study, we observed that adult females show increased mortality compared with their male counterparts. Differences in inflammatory responses underlie this observation, contributing to the observed poor outcomes. Importantly, sex differences in post-burn responses appear to diminish with age, highlighting the importance of deepening our understanding of the underlying physiologic mechanisms to optimize patient care.</p>","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Incidence of Arterial Pressure Line Insufficiency Between Polyethylene and Polyurethane Catheters in the ICU: A Randomized Study.","authors":"Kimito Minami, Masahiro Kazawa, Tatsutoshi Shimatani, Masahiro Morinaga, Akira Shimokawa, Takuma Maeda, Muneyuki Takeuchi","doi":"10.1097/CCM.0000000000006794","DOIUrl":"https://doi.org/10.1097/CCM.0000000000006794","url":null,"abstract":"<p><strong>Objectives: </strong>Continuous arterial pressure monitoring is crucial for critically ill patients. However, the impact of catheter type on arterial line insufficiency remains unexamined.</p><p><strong>Design: </strong>Double-blinded, superiority, randomized controlled trial.</p><p><strong>Setting: </strong>A cardiovascular center in Japan.</p><p><strong>Patients: </strong>Adult patients scheduled for elective cardiovascular surgery and postoperative admission to the ICU.</p><p><strong>Interventions: </strong>Patients were randomly assigned either polyethylene or polyurethane catheters.</p><p><strong>Measurements and main results: </strong>The outcome of interest was arterial line insufficiency, defined by one or more of the following four criteria: flattened or overdamped blood pressure waveform, sluggish free backflow of blood (> 2 s) when the stopcock was opened to the atmosphere, inability to draw blood from the arterial line, and inability to flush the catheter. The frequency of arterial line insufficiency was observed at the first noon after ICU admission. An interim analysis using the chi-square test was performed after half of the participants were enrolled, with early termination if p value of less than 0.005 based on the O'Brien-Fleming method. Interim analysis of 132 patients revealed significant differences in primary outcomes, leading to early termination of the trial. Arterial line insufficiency occurred in four of 69 patients (5.8%) with polyethylene catheters and 18 of 63 patients (28.6%) with polyurethane catheters (relative risk, 0.15; 95% CI, 0.05-0.48; p = 0.001).</p><p><strong>Conclusions: </strong>This study demonstrated a lower occurrence rate of arterial line insufficiency with polyethylene arterial catheters than polyurethane catheters.</p>","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Rhythm Conversions and the Outcome in Refractory Out-of-Hospital Cardiac Arrest: Extracorporeal Versus Conventional Resuscitation.","authors":"Stepan Havranek, Jakub Neuhöfer, Michaela Vesela, Petra Kavalkova, Daniel Rob, Zdenka Fingrova, Jana Smalcova, Ondrej Franek, Michal Huptych, Milan Dusik, Jan Pudil, Vojtech Weiss, Ales Linhart, Jan Belohlavek","doi":"10.1097/CCM.0000000000006787","DOIUrl":"10.1097/CCM.0000000000006787","url":null,"abstract":"<p><strong>Objectives: </strong>A Prague out-of-hospital cardiac arrest (OHCA) study has demonstrated that an invasive approach (early transport to the hospital, extracorporeal cardiopulmonary resuscitation [ECPR]) is a feasible and effective treatment strategy in refractory OHCA. This post hoc analysis of the Prague OHCA study aimed to stratify the prognosis of patients according to the detailed course of heart rhythm during prehospital and early hospital periods.</p><p><strong>Design, setting, and patients: </strong>This analysis included all 256 patients (median age 58, 17% females) randomized to the Prague OHCA study. The sequence of heart rhythms during the prehospital period was analyzed in terms of neurologic outcomes after 180 days. The primary outcome was a composite of survival with Cerebral Performance Category 1 or 2 at 180 days.</p><p><strong>Interventions: </strong>None.</p><p><strong>Measurements and main results: </strong>Within the study cohort, 156 (61%) manifested ventricular fibrillation (VF), 45 pulseless electrical activity, and 55 asystole as the initial rhythm. Patients with an initial VF who reached a sustained recovery of spontaneous circulation (ROSC) had the highest proportion of reaching a primary outcome (32/44 [73%]). Patients who had one or more episodes of asystole during cardiopulmonary resuscitation had the lowest rate of primary endpoint (5/39 [13%]). Patients who experienced intermittent ROSC showed a higher success rate in achieving the primary outcome when treated with an invasive-based approach (including ECPR) compared with the conventional strategy (26/34 [76%] vs. 24/50 [48%]; p < 0.05).</p><p><strong>Conclusions: </strong>Achieving ROSC is the best prognostic marker in OHCA patients with an initially refractory VF. Patients with intermittent ROSC after the initial VF and ongoing VF seem to be optimal candidates for an invasive approach. Asystole detection at any time during resuscitation is a strong negative prognostic marker, irrespective of the initial rhythm.</p>","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Sepsis Chain of Survival: A Comprehensive Framework for Improving Sepsis Outcomes.","authors":"Jorge L Hidalgo, Vishakha K Kumar, Samuel O Akech, Sheila N Myatra, Shevin T Jacob, Teresa Kortz, Amanda A Vasquez, Maria Cristina Jiménez Bazzano, Marilia Diaz, Jennifer Del Rio Rodríguez, Ana Luisa Najera Garcia, Rocio Giron, Judith Jacobi, Maureen A Madden, Vinay Nadkarni","doi":"10.1097/CCM.0000000000006796","DOIUrl":"10.1097/CCM.0000000000006796","url":null,"abstract":"<p><p>The \"Chain of Survival\" concept, developed for cardiac arrest, emphasizes a seamless and interconnected set, of time-critical interventions that are not strictly linear, to improve survival. This paradigm of urgent recognition and response to life-threatening conditions has evolved to apply to acute medical conditions, including sepsis. The \"Sepsis Chain of Survival\" underscores the importance of early recognition, prompt emergency medical services activation, timely antimicrobial administration and appropriate fluid resuscitation, optimized critical care management, effective source control and infection management, and comprehensive post-sepsis care. By adopting this approach, healthcare systems can improve sepsis outcomes through a coordinated, multifaceted strategy. This model highlights the critical role of public and healthcare worker awareness, education, community response, and continuous monitoring. Addressing the importance and interdependence of each link, this framework aims to improve survival rates and patient recovery by ensuring timely and effective sepsis management across diverse resource settings in infants, children, and adults.</p>","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Risk to Recovery: Predicting Quality of Life After Critical Illness.","authors":"Kimia Honarmand","doi":"10.1097/CCM.0000000000006776","DOIUrl":"10.1097/CCM.0000000000006776","url":null,"abstract":"","PeriodicalId":10765,"journal":{"name":"Critical Care Medicine","volume":" ","pages":""},"PeriodicalIF":7.7,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}