Critical Reviews in Microbiology最新文献_第7页

Outer membrane proteins and vesicles as promising vaccine candidates against Vibrio spp. infections. 外膜蛋白和囊泡有望成为预防弧菌感染的候选疫苗。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-08-01 Epub Date: 2023-06-05 DOI: 10.1080/1040841X.2023.2212072

Brijeshwar Singh, Surbhi Jaiswal, Prashant Kodgire

引用次数: 0

Acinetobacter baumannii subunit vaccines: recent progress and challenges. 鲍曼不动杆菌亚单位疫苗：最新进展与挑战。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-08-01 Epub Date: 2023-05-21 DOI: 10.1080/1040841X.2023.2215303

Yi Teng Lau, Hock Siew Tan

{"title":"Acinetobacter baumannii subunit vaccines: recent progress and challenges.","authors":"Yi Teng Lau, Hock Siew Tan","doi":"10.1080/1040841X.2023.2215303","DOIUrl":"10.1080/1040841X.2023.2215303","url":null,"abstract":"Acinetobacter baumannii is a Gram-negative, opportunistic pathogen that causes nosocomial infection with a high mortality rate in immunocompromised individuals. With the frequent emergence of multidrug-resistant A. baumannii strains that have rapidly gained resistance to most antibiotics, an extensive search for an effective A. baumannii vaccine is ongoing. Over the decade, many subunit vaccine candidates were identified using reverse vaccinology and in vivo animal studies for validation. Nineteen subunit vaccine candidates with a wide range of efficacy, from 14% to 100% preclinical survival rates, were included in this review. This article provides an updated review of several outer membrane proteins (Omp) that emerged as vaccine candidates with great potential, including OmpA, Omp34, Omp22 and BamA, based on their high conservancy, antigenicity, and immune protection against A. baumannii infection. However, there is still no licenced A. baumannii vaccine currently due to several practical issues that have yet to be resolved, such as inconsistencies between validation studies, antigen variability and insolubility. Moving forward, much investigation and innovation are still required to tackle these challenges for the regulatory approval of an A. baumannii subunit vaccine, including standardisation of immunisation study parameters, improving antigen solubility and the incorporation of nucleic acid vaccine technology.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"434-449"},"PeriodicalIF":6.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9552033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Damage-associated molecular patterns in viral infection: potential therapeutic targets. 病毒感染中的损伤相关分子模式：潜在的治疗目标。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-08-01 DOI: 10.1080/1040841X.2024.2384885

Huizhen Tian, Qiong Liu, Xiaomin Yu, Yanli Cao, Xiaotian Huang

引用次数: 0

Towards the discovery of novel molecular clocks in Prokaryotes. 在原核生物中发现新的分子钟。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-08-01 Epub Date: 2023-06-18 DOI: 10.1080/1040841X.2023.2220789

Augustin Géron, Johannes Werner, Ruddy Wattiez, Sabine Matallana-Surget

{"title":"Towards the discovery of novel molecular clocks in Prokaryotes.","authors":"Augustin Géron, Johannes Werner, Ruddy Wattiez, Sabine Matallana-Surget","doi":"10.1080/1040841X.2023.2220789","DOIUrl":"10.1080/1040841X.2023.2220789","url":null,"abstract":"Diel cycle is of enormous biological importance as it imposes daily oscillation in environmental conditions, which temporally structures most ecosystems. Organisms developed biological time-keeping mechanisms - circadian clocks - that provide a significant fitness advantage over competitors by optimising the synchronisation of their biological activities. While circadian clocks are ubiquitous in Eukaryotes, they are so far only characterised in Cyanobacteria within Prokaryotes. However, growing evidence suggests that circadian clocks are widespread in the bacterial and archaeal domains. As Prokaryotes are at the heart of crucial environmental processes and are essential to human health, unravelling their time-keeping systems provides numerous applications in medical research, environmental sciences, and biotechnology. In this review, we elaborate on how novel circadian clocks in Prokaryotes offer research and development perspectives. We compare and contrast the different circadian systems in Cyanobacteria and discuss about their evolution and taxonomic distribution. We necessarily provide an updated phylogenetic analysis of bacterial and archaeal species that harbour homologs of the main cyanobacterial clock components. Finally, we elaborate on new potential clock-controlled microorganisms that represent opportunities of ecological and industrial relevance in prokaryotic groups such as anoxygenic photosynthetic bacteria, methanogenic archaea, methanotrophs or sulphate-reducing bacteria.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"491-503"},"PeriodicalIF":6.0,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9642323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Polyamine as a microenvironment factor in resistance to antibiotics. 多胺是抗生素耐药性的微环境因素。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-08-01 Epub Date: 2023-06-20 DOI: 10.1080/1040841X.2023.2223277

Amrita C Bhagwat, Sunil D Saroj

引用次数: 0

Macrophage biology in the pathogenesis of Helicobacter pylori infection. 幽门螺旋杆菌感染发病机制中的巨噬细胞生物学。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-07-31 DOI: 10.1080/1040841X.2024.2366944

Xiao Fei, Nianshuang Li, Xinbo Xu, Yin Zhu

引用次数: 0

Gut microbiota-lncRNA/circRNA crosstalk: implications for different diseases. 肠道微生物群-lncRNA/circRNA串扰：对不同疾病的影响。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-07-05 DOI: 10.1080/1040841X.2024.2375516

Lei Zhang, Xin Li, Huijuan Gao, Wenguang Chang, Peifeng Li

{"title":"Gut microbiota-lncRNA/circRNA crosstalk: implications for different diseases.","authors":"Lei Zhang, Xin Li, Huijuan Gao, Wenguang Chang, Peifeng Li","doi":"10.1080/1040841X.2024.2375516","DOIUrl":"https://doi.org/10.1080/1040841X.2024.2375516","url":null,"abstract":"The gut microbiota features an abundance of diverse microorganisms and represents an important component of human physiology and metabolic homeostasis, indicating their roles in a wide array of physiological and pathological processes in the host. Maintaining balance in the gut microbiota is critical for normal functionality as microbial dysbiosis can lead to the occurrence and development of diseases through various mechanisms. Long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs) are non-coding RNAs that perform important regulatory functions for many processes. Furthermore, the gut microbiota and lncRNAs/circRNAs are known to interact in a range of both physiological and pathological activities. In this article, we review existing research relevant to the interaction between the gut microbiota and lncRNAs/circRNAs and investigate the role of their crosstalk in the pathogenesis of different diseases. Studies have shown that, the gut microbiota can target lncRNAs ENO1-IT1, BFAL1, and LINC00152 to regulate colorectal cancer development via various signaling pathways. In addition, the gut microbiota can influence mental diseases and lung tumor metastasis by modulating circRNAs such as circNF1-419, circ_0001239, circHIPK2 and mmu_circ_0000730. These findings provide a theoretical basis for disease prevention and treatment and suggest that gut microbiota-lncRNA/circRNA crosstalk has high clinical value.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-15"},"PeriodicalIF":6.0,"publicationDate":"2024-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141533911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current and novel therapies for management of Acinetobacter baumannii-associated pneumonia. 治疗鲍曼不动杆菌相关肺炎的现有疗法和新型疗法。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-07-01 DOI: 10.1080/1040841X.2024.2369948

Aye Mya Sithu Shein, Parichart Hongsing, O'Rorke Kevin Smith, Phatthranit Phattharapornjaroen, Kazuhiko Miyanaga, Longzhu Cui, Hitoshi Ishikawa, Mohan Amarasiri, Peter N Monk, Anthony Kicic, Tanittha Chatsuwan, Daniel Pletzer, Paul G Higgins, Shuichi Abe, Dhammika Leshan Wannigama

{"title":"Current and novel therapies for management of Acinetobacter baumannii-associated pneumonia.","authors":"Aye Mya Sithu Shein, Parichart Hongsing, O'Rorke Kevin Smith, Phatthranit Phattharapornjaroen, Kazuhiko Miyanaga, Longzhu Cui, Hitoshi Ishikawa, Mohan Amarasiri, Peter N Monk, Anthony Kicic, Tanittha Chatsuwan, Daniel Pletzer, Paul G Higgins, Shuichi Abe, Dhammika Leshan Wannigama","doi":"10.1080/1040841X.2024.2369948","DOIUrl":"https://doi.org/10.1080/1040841X.2024.2369948","url":null,"abstract":"Acinetobacter baumannii is a common pathogen associated with hospital-acquired pneumonia showing increased resistance to carbapenem and colistin antibiotics nowadays. Infections with A. baumannii cause high patient fatalities due to their capability to evade current antimicrobial therapies, emphasizing the urgency of developing viable therapeutics to treat A. baumannii-associated pneumonia. In this review, we explore current and novel therapeutic options for overcoming therapeutic failure when dealing with A. baumannii-associated pneumonia. Among them, antibiotic combination therapy administering several drugs simultaneously or alternately, is one promising approach for optimizing therapeutic success. However, it has been associated with inconsistent and inconclusive therapeutic outcomes across different studies. Therefore, it is critical to undertake additional clinical trials to ascertain the clinical effectiveness of different antibiotic combinations. We also discuss the prospective roles of novel antimicrobial therapies including antimicrobial peptides, bacteriophage-based therapy, repurposed drugs, naturally-occurring compounds, nanoparticle-based therapy, anti-virulence strategies, immunotherapy, photodynamic and sonodynamic therapy, for utilizing them as additional alternative therapy while tackling A. baumannii-associated pneumonia. Importantly, these innovative therapies further require pharmacokinetic and pharmacodynamic evaluation for safety, stability, immunogenicity, toxicity, and tolerability before they can be clinically approved as an alternative rescue therapy for A. baumannii-associated pulmonary infections.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-22"},"PeriodicalIF":6.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141466773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fusarium and Neocosmospora: fungal priority pathogens in laboratory diagnosis. 镰刀菌和新孢子菌：实验室诊断中的真菌重点病原体。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-07-01 DOI: 10.1080/1040841X.2024.2369693

Valeri Sáenz, Andrés Felipe Lizcano Salas, Josepa Gené, Adriana Marcela Celis Ramírez

引用次数: 0

Host and bacterial lipid metabolism during tuberculosis infections: possibilities to synergise host- and bacteria-directed therapies. 结核病感染期间宿主和细菌的脂质代谢：协同宿主和细菌导向疗法的可能性。

IF 6 2区生物学

Critical Reviews in Microbiology Pub Date : 2024-06-25 DOI: 10.1080/1040841X.2024.2370979

Teun van der Klugt, Robin H G A van den Biggelaar, Anno Saris

{"title":"Host and bacterial lipid metabolism during tuberculosis infections: possibilities to synergise host- and bacteria-directed therapies.","authors":"Teun van der Klugt, Robin H G A van den Biggelaar, Anno Saris","doi":"10.1080/1040841X.2024.2370979","DOIUrl":"10.1080/1040841X.2024.2370979","url":null,"abstract":"Mycobacterium tuberculosis (Mtb) is the causative pathogen of tuberculosis, the most lethal infectious disease resulting in 1.3 million deaths annually. Treatments against Mtb are increasingly impaired by the growing prevalence of antimicrobial drug resistance, which necessitates the development of new antibiotics or alternative therapeutic approaches. Upon infecting host cells, predominantly macrophages, Mtb becomes critically dependent on lipids as a source of nutrients. Additionally, Mtb produces numerous lipid-based virulence factors that contribute to the pathogen's ability to interfere with the host's immune responses and to create a lipid rich environment for itself. As lipids, lipid metabolism and manipulating host lipid metabolism play an important role for the virulence of Mtb, this review provides a state-of-the-art overview of mycobacterial lipid metabolism and concomitant role of host metabolism and host-pathogen interaction therein. While doing so, we will emphasize unexploited bacteria-directed and host-directed drug targets, and highlight potential synergistic drug combinations that hold promise for the development of new therapeutic interventions.","PeriodicalId":10736,"journal":{"name":"Critical Reviews in Microbiology","volume":" ","pages":"1-21"},"PeriodicalIF":6.0,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141445849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0