Coronary artery disease最新文献_第3页

Efficacy of paclitaxel-coated versus uncoated balloon angioplasty for revascularization of coronary in-stent restenosis: a meta-analysis and metaregression. 紫杉醇包被与非包被球囊血管成形术对冠状动脉支架内再狭窄血运重建的疗效：一项荟萃分析和荟萃回归。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-13 DOI: 10.1097/MCA.0000000000001534

Mrinal Murali Krishna, Meghna Joseph, Chidubem Ezenna, Vinicius Pereira, Ancy Jenil Franco, Mahmoud Ismayl, Jennifer Rymer, Andrew M Goldsweig

{"title":"Efficacy of paclitaxel-coated versus uncoated balloon angioplasty for revascularization of coronary in-stent restenosis: a meta-analysis and metaregression.","authors":"Mrinal Murali Krishna, Meghna Joseph, Chidubem Ezenna, Vinicius Pereira, Ancy Jenil Franco, Mahmoud Ismayl, Jennifer Rymer, Andrew M Goldsweig","doi":"10.1097/MCA.0000000000001534","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001534","url":null,"abstract":"Background: Treatment of in-stent restenosis (ISR) accounts for 10% of percutaneous coronary interventions in the USA. Paclitaxel-coated balloons (PCBs) are an alternative to uncoated balloons (UCBs) for ISR.Methods: We systematically searched PubMed, Scopus, and Cochrane Central for studies comparing PCB with UCB in treating ISR. Outcomes included late lumen loss, binary restenosis, target lesion revascularization (TLR), and major adverse cardiovascular events (MACE).Results: Eight trials including 1410 patients [PCB in 865 (61%), follow-up 6 months to 10 years) were identified. Angiographic outcomes of late lumen loss [mean difference: -0.50 mm; 95% confidence interval (CI): -0.66 to -0.33; P < 0.01] and binary restenosis [relative risk (RR): 0.22; 95% CI: 0.13-0.40; P < 0.01] at 6-8 months were lower with PCB. TLR at 6 months (RR: 0.16; 95% CI: 0.06-0.40; P < 0.001) and 1 year (RR: 0.45; 95% CI: 0.31-0.66; P < 0.001), MACE at 6 months (RR: 0.25; 95% CI: 0.16-0.38; P < 0.001), MACE at 3-5 years (RR: 0.54; 95% CI: 0.37-0.80; P = 0.002), and TLR at 3-5 years (RR: 0.51; 95% CI: 0.29-0.90; P = 0.021) were lower with PCB. Meta-regression revealed that ISR lesions in the left anterior descending artery were associated with lower rates of binary restenosis while the opposite was observed for left circumflex lesions.Conclusion: Revascularization of coronary ISR with PCB is associated with reduced late lumen loss, binary restenosis, TLR, CCE, and MACE. PCB may be a preferred strategy for coronary ISR.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optical frequency domain imaging versus intravascular ultrasound for percutaneous coronary intervention: a meta-analysis and trial sequential analysis of randomized controlled trials. 经皮冠状动脉介入治疗的光学频域成像与血管内超声：随机对照试验的荟萃分析和试验序列分析。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-12 DOI: 10.1097/MCA.0000000000001535

Hosam I Taha, Mohamed S Elgendy, Abdalhakim Shubietah, Ahmed Mazen Amin, Mohamed R Ezz, Abdelrahman M Ghazal, Mohamed Anas ElShanat, Hazem Zayan, Khalid Tolba, Mohamed Abuelazm, Islam Y Elgendy

{"title":"Optical frequency domain imaging versus intravascular ultrasound for percutaneous coronary intervention: a meta-analysis and trial sequential analysis of randomized controlled trials.","authors":"Hosam I Taha, Mohamed S Elgendy, Abdalhakim Shubietah, Ahmed Mazen Amin, Mohamed R Ezz, Abdelrahman M Ghazal, Mohamed Anas ElShanat, Hazem Zayan, Khalid Tolba, Mohamed Abuelazm, Islam Y Elgendy","doi":"10.1097/MCA.0000000000001535","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001535","url":null,"abstract":"Intravascular ultrasound (IVUS) or optical frequency domain imaging (OFDI) for guiding percutaneous coronary interventions (PCI) reduces the risk of adverse events compared with angiographic guidance. However, only a few trials compared both modalities. This study aims to assess and compare OFDI- vs. IVUS-guided PCI. We conducted a meta-analysis of randomized controlled trials (RCTs) retrieved from PubMed, Scopus, WOS, Embase, and Cochrane Library till September 2024. The primary outcome was major adverse cardiac events (MACE). Risk ratios (RR) were applied for dichotomous outcomes and mean differences (MD) for continuous outcomes, both with 95% confidence intervals (CI). PROSPERO ID: CRD42024595477. Four RCTs with 1135 patients were included. There was no significant difference between the two modalities in terms of MACE [RR: 0.99; 95% CI: (0.53, 1.86); P = 0.98], all-cause mortality [RR: 0.72; 95% CI: (0.15, 3.56); P = 0.69], cardiac mortality [RR: 1.00; 95% CI: (0.18, 5.68); P = 1.00] and myocardial infarction [RR: 1.21; 95% CI: (0.35, 4.18); P = 0.76]. Additionally, there was no significant difference in PCI success [RR: 1.00; 95% CI: (0.99, 1.02); P = 0.64]. However, OFDI was associated with a significant increase in contrast volume [MD: 19.81 ml; 95% CI: (2.53, 37.09); P = 0.02] and reduction in fluoroscopy time [MD: -7.05 min; 95% CI: (-9.32, -4.79); P < 0.01]. This meta-analysis of RCTs suggests that OFDI is comparable to IVUS in efficacy and safety for guiding PCI, with no significant differences in clinical outcomes. These findings support the use of either modality for PCI guidance. However, additional large-scale, multicenter RCTs to recommended to validate these findings and enhance their generalizability.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Urinary sodium-potassium ratio as a genetic predictor of myocardial infarction. 尿钠钾比作为心肌梗死的遗传预测因子。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-06 DOI: 10.1097/MCA.0000000000001532

Ziyang Wu, Dong Wang, Chengchun Tang

{"title":"Urinary sodium-potassium ratio as a genetic predictor of myocardial infarction.","authors":"Ziyang Wu, Dong Wang, Chengchun Tang","doi":"10.1097/MCA.0000000000001532","DOIUrl":"https://doi.org/10.1097/MCA.0000000000001532","url":null,"abstract":"Background: The relationship between the urinary sodium-potassium ratio (USPR) and risk factors for heart disease has been observed over time. We evaluated the relationship between USPR and myocardial infarction (MI).Methods: Causal relationships were estimated based on USPR and MI data from genome-wide association studies. The main analysis method for bidirectional two-sample Mendelian randomization was inverse-variance weighting (IVW), with four other supplementary methods used.Results: The IVW method indicated a positive correlation between USPR levels and MI (IVW, odds ratio = 1.504, 95% confidence interval: 1.108-2.041, P = 0.009). In contrast, the inverse analysis provided evidence suggesting that MI affected USPR (P > 0.05). The Cochran Q test showed heterogeneity, while the intercept test revealed no horizontal pleiotropy, and the leave-one-out analysis demonstrated that the analyses were reliable.Conclusions: This study provides evidence for the causal effect of the USPR on MI; however, this was not the case in the opposite situation. It is plausible that the USPR serves as a promoting factor for MI.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of new postoperative atrial fibrillation after cardiac surgery. 心脏手术后新发房颤的风险。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-01 Epub Date: 2025-03-26 DOI: 10.1097/MCA.0000000000001472

Mesut Engin, İsmail Sivri

引用次数: 0

Predicting postoperative atrial fibrillation after cardiac surgery using the Naples prognostic score. 应用那不勒斯预后评分预测心脏手术后房颤。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-01 Epub Date: 2024-10-24 DOI: 10.1097/MCA.0000000000001438

Dogac Oksen, Baris Guven, Ayca Donmez, Mehmet Ali Yesiltas, Ahmet Ozan Koyuncu, Seran Gulbudak, Veysel Oktay

{"title":"Predicting postoperative atrial fibrillation after cardiac surgery using the Naples prognostic score.","authors":"Dogac Oksen, Baris Guven, Ayca Donmez, Mehmet Ali Yesiltas, Ahmet Ozan Koyuncu, Seran Gulbudak, Veysel Oktay","doi":"10.1097/MCA.0000000000001438","DOIUrl":"10.1097/MCA.0000000000001438","url":null,"abstract":"Introduction: The Naples prognostic score (NPS) is a novel indicator of nutritional and inflammatory statuses in cancer patients. Development of atrial fibrillation after cardiac surgery (POAF) is a common complication that increases the incidence of adverse events. Numerous studies have investigated predictors of POAF. Yet, this study is the first to evaluate the prognostic value of NPS in predicting the development of POAF.Materials and methods: The population of this retrospective single-center case-control study consisted of all consecutive patients who underwent cardiac surgery between January 2021 and December 2023. The patients included in the study sample were divided into two groups according to whether they had POAF (group POAF) or remained in sinus rhythm (group RSR). Univariate and multivariate analyses were conducted to identify the variables that significantly predicted the development of POAF.Results: This study consisted of 860 patients with a mean age of 61.77 ± 9.13 years and 77.5% ( n = 667) were male. The incidence of POAF in the sample was 24.8% ( n = 214). NPS was significantly higher in group POAF than in group RSR (2.18 ± 0.99 vs. 1.96 ± 1.02, P = 0.008). Multivariate analysis revealed age [odds ratio (OR): 1.242, 95% confidence interval (CI): 1.020-1.304, P < 0.001] and high NPS (OR: 1.698, 95% CI: 1.121-1.930, P < 0.010) as independent predictors of POAF.Conclusion: High NPS values, along with advanced age, were found to be strongly associated with an increased risk of developing POAF. Therefore, it is concluded that NPS is a significant and independent predictor of POAF in patients undergoing cardiac surgery.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"225-231"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11949236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142946189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Culprit vessel revascularization prior to complete angiography as a strategy to minimize delays in primary percutaneous coronary intervention for patients with ST-elevation myocardial infarction: a systematic review and meta-analysis. 在完全血管造影前进行病变血管再通术，作为尽量减少ST段抬高型心肌梗死患者经皮冠状动脉介入治疗延迟的策略：系统综述和荟萃分析。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-01 Epub Date: 2024-10-31 DOI: 10.1097/MCA.0000000000001450

Elísio Bulhões, Vanio L J Antunes, Maria L R Defante, Roberto Mazetto, Anselmo C Garcia, Thiago C C Garcia, Camila Guida

{"title":"Culprit vessel revascularization prior to complete angiography as a strategy to minimize delays in primary percutaneous coronary intervention for patients with ST-elevation myocardial infarction: a systematic review and meta-analysis.","authors":"Elísio Bulhões, Vanio L J Antunes, Maria L R Defante, Roberto Mazetto, Anselmo C Garcia, Thiago C C Garcia, Camila Guida","doi":"10.1097/MCA.0000000000001450","DOIUrl":"10.1097/MCA.0000000000001450","url":null,"abstract":"The rapid restoration of blood flow in patients with acute myocardial infarction with ST elevation through percutaneous coronary intervention (PCI) is crucial for the survival of this population. Attempts to decrease the time from diagnosis of ST-segment elevation myocardial infarction (STEMI) to arrival at the catheterization laboratory have been extensively investigated. However, strategies during the procedure aiming to reduce the time to reperfusion are lacking. We conducted a meta-analysis to evaluate culprit vessel revascularization prior to complete angiography as a strategy to minimize delays in primary PCI for patients with STEMI. We searched PubMed, Embase, and Cochrane Central. Outcomes: vascular access-to-balloon, door-to-balloon, and first medical contact-to-balloon times; death, reinfarction in 30 days, Bleeding Academic Research Consortium ≥3 type, coronary artery bypass grafting referral, and left ventricular ejection fraction %. Statistical analysis was performed using the R program (version 4.3.2). Heterogeneity was assessed with I2 statistics. We included 2050 patients from six studies, of which two were randomized controlled trials and four were observational studies. Culprit vessel revascularization prior to complete angiography was associated with a statistically significant decrease of times: vascular access-to-balloon time (mean difference -6.79 min; 95% CI: -8.00 to -5.58; P < 0.01; I2 = 82%) and door-to-balloon time (mean difference -9.02 min; 95% CI: -12.83 to -5.22; P < 0.01; I2 = 93%). In this meta-analysis, performing PCI on the culprit lesion prior to complete coronary angiography led to significantly shorter reperfusion times, with no discernible differences in complication rates.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"232-239"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142544224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anomalous left main coronary artery originating from right coronary artery. 起源于右冠状动脉的左冠状动脉主干异常。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-01 Epub Date: 2024-06-14 DOI: 10.1097/MCA.0000000000001404

Xingzhou Zhao, Zhanwen Xu

引用次数: 0

Zero-contrast intravascular ultrasound-guided percutaneous coronary intervention in a patient with high-risk iodinated contrast allergy: navigating in the dark through a brighter inner light. 零对比度血管内超声引导下经皮冠状动脉介入治疗对碘造影剂过敏的高危患者：通过更明亮的内在光线在黑暗中导航。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-01 Epub Date: 2024-10-24 DOI: 10.1097/MCA.0000000000001444

Giuseppe Colletti, Asad Shabbir, Alexandre Natalis, Claudiu Ungureanu

引用次数: 0

Hair cortisol concentration, a stress biomarker, is gradually increasing before an acute myocardial infarction. 毛发皮质醇浓度，一种应激生物标志物，在急性心肌梗死前逐渐升高。

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-01 Epub Date: 2024-12-03 DOI: 10.1097/MCA.0000000000001468

Nikolaos Kosmas, Panagiotis Simitsis, Evangelos Alevyzakis, Emmanouil Rizos, Dimitrios Zapantiotis, Loukianos Stylianos Rallidis

{"title":"Hair cortisol concentration, a stress biomarker, is gradually increasing before an acute myocardial infarction.","authors":"Nikolaos Kosmas, Panagiotis Simitsis, Evangelos Alevyzakis, Emmanouil Rizos, Dimitrios Zapantiotis, Loukianos Stylianos Rallidis","doi":"10.1097/MCA.0000000000001468","DOIUrl":"10.1097/MCA.0000000000001468","url":null,"abstract":"Background: Chronic stress is believed to play a role in the pathophysiology of acute myocardial infarction (AMI). Cortisol is a biomarker associated with stress. We sought to assess stress contribution to AMI using hair cortisol concentration (HCCs) as a surrogate biomarker.Methods: HCC was measured in hair segments, corresponding to distinctive periods before hair sampling, in 102 male AMI patients and 50 healthy male controls. Standard baseline variables were collected for both groups, whereas for AMI patients, laboratory and psychological tests were also carried out. Linear mixed models were applied to assess the effect of group and baseline variables on the trend of cortisol before hair sampling.Results: HCC was significantly higher in AMI patients the last 30 days before hair sampling with an overall higher rate of increase (time-group interaction P < 0.001). AMI patients with BMI ≥25 kg/m 2 had a slower rate of increase compared with those with BMI <25 kg/m 2 (adjusted P = 0.008). Among AMI patients, there was no difference in the rate of cortisol increase between STEMI and NSTEMI patients (time-group interaction P = 0.841). Lower BMI conferred higher rates of cortisol increase irrespectively of AMI type.Conclusion: HCC, a biomarker of stress, showed an increasing trend over a period of 2 months before the occurrence of AMI suggesting a potential role of stress, through cortisol secretion, in the pathophysiology of AMI.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"218-224"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142767006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Positive correlation between n- 6 : n- 3 PUFA ratio intake with serum oxHDL/HDL-c ratio in patients with coronary artery disease. 冠心病患者n-6: n-3 PUFA比值摄入与血清oxHDL/HDL-c比值正相关

IF 1.5 4区医学

Coronary artery disease Pub Date : 2025-05-01 Epub Date: 2024-10-16 DOI: 10.1097/MCA.0000000000001437

Sissi Godinez-Mora, Wendy Campos-Perez, Mariana Perez-Robles, Cesar Robles-Jimarez, Alejandra Muñoz-Hernandez, Joel Torres-Vanegas, Erika Martinez-Lopez

{"title":"Positive correlation between n- 6 : n- 3 PUFA ratio intake with serum oxHDL/HDL-c ratio in patients with coronary artery disease.","authors":"Sissi Godinez-Mora, Wendy Campos-Perez, Mariana Perez-Robles, Cesar Robles-Jimarez, Alejandra Muñoz-Hernandez, Joel Torres-Vanegas, Erika Martinez-Lopez","doi":"10.1097/MCA.0000000000001437","DOIUrl":"10.1097/MCA.0000000000001437","url":null,"abstract":"Background: Coronary artery disease (CAD) is one of the most prevalent cardiovascular diseases where serum lipoprotein oxidation plays a significant role. Polyunsaturated fatty acids (PUFA) n -6 : n -3 unbalance ratio consumption, affects lipoprotein oxidation, and inflammation processes. This study aimed to analyze the relationship between n -6 : n -3 PUFA ratio intake with oxidized lipoproteins in individuals with CAD.Methods: A cross-sectional study was performed including 105 subjects (51 diagnosed with CAD and 54 non-CAD) from western Mexico. Dietary information was collected using a habitual day food record. Serum oxidized low-density lipoprotein (oxLDL) and oxidized high-density lipoprotein (oxHDL) concentrations were quantified by enzyme linked immunosorbent assay.Results: CAD subjects had higher oxHDL/HDL cholesterol (HDL-c) ratio [0.102 (0.092-0.112) vs. 0.080 (0.070-0.090), P = 0.004] and oxLDL/LDL cholesterol (LDL-c) ratio [129.2 (108-150.4) vs. 59.7 (39.3-80), P < 0.001] compared to non-CAD subjects. Risk factors associated with CAD were a high n -6 : n -3 PUFA ratio (odds ratio, OR = 2.3, P = 0.046), hypoalphalipoproteinemia in men (OR = 3.2, P = 0.014), moderate/high tobacco index (OR = 6.33, P = 0.003), elevated waist circumference in women (OR = 7, P = 0.004), hypertension (OR = 21.14, P < 0.001), and type 2 diabetes (OR: 25, P < 0.001). The oxHDL/HDL-c ratio was positively associated with the n -6 : n -3 PUFA ratio [ r2 = 28.3, B = 0.002 (0.001-0.003), P < 0.001] in CAD patients.Conclusions: This study showed that a higher n -6 : n -3 PUFA ratio intake correlates with higher serum oxHDL/HDL-c in CAD patients.","PeriodicalId":10702,"journal":{"name":"Coronary artery disease","volume":" ","pages":"190-199"},"PeriodicalIF":1.5,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142892702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0