Clinical radiologyPub Date : 2026-02-01Epub Date: 2025-12-13DOI: 10.1016/j.crad.2025.107214
M. Kengsakul , H.J. van Beekhuizen , A. Bijleveld , D.C. Plak , B.M. de Kok , I.G. Schoots , J.M.J. Piek , S.J. Kerr , M.G.J. Thomeer , G.M. Nieuwenhuyzen-de Boer
{"title":"Substantial discordance between structured pre-operative computed tomography (CT) reports and intraoperative findings in advanced ovarian cancer cytoreductive surgery, affecting treatment decisions","authors":"M. Kengsakul , H.J. van Beekhuizen , A. Bijleveld , D.C. Plak , B.M. de Kok , I.G. Schoots , J.M.J. Piek , S.J. Kerr , M.G.J. Thomeer , G.M. Nieuwenhuyzen-de Boer","doi":"10.1016/j.crad.2025.107214","DOIUrl":"10.1016/j.crad.2025.107214","url":null,"abstract":"<div><h3>AIM</h3><div>The aim of this study was to assess the agreement and diagnostic accuracy of structured preoperative computed tomography (CT) findings compared to intraoperative findings in advanced ovarian cancer patients undergoing primary or interval cytoreductive surgery.</div></div><div><h3>MATERIALS AND METHODS</h3><div>Patients with CT scans suggesting advanced ovarian cancer were enrolled in the study. Agreement between CT reports, reviewed using European Society of Urogenital Radiology (ESUR) criteria, and surgical findings were evaluated with the kappa coefficient. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated for each radiologic feature.</div></div><div><h3>RESULTS</h3><div>From February 2018 to September 2020, 258 patients with International Federation of Gynaecology and Obstetrics (FIGO) stage IIIB-IV epithelial ovarian cancer were enrolled. Agreement between ESUR-reviewed CT reports and surgical findings was slight to fair (kappa = 0.115–0.352). The most common CT findings were peritoneal carcinomatosis, omental metastases, and bowel involvement. Sensitivity and specificity of peritoneal carcinomatosis were 0.91 (95% confidence interval [CI]: 0.86–0.94) and 0.19 (95% CI: 0.10–0.31), with an area under the receiver operating characteristic curve (AUC) of 0.55 (95% CI: 0.46–0.64). Omental metastases had a sensitivity of 0.91 (95% CI: 0.87–0.95) and specificity of 0.27 (95% CI: 0.16–0.40) with an AUC of 0.59 (95% CI: 0.52–0.65). Bowel involvement showed a sensitivity of 0.61 (95% CI: 0.54–0.67), specificity of 0.71 (95% CI: 0.58–0.83), and AUC of 0.66 (95% CI: 0.58–0.74).</div></div><div><h3>CONCLUSION</h3><div>This study demonstrates limited concordance between ESUR-reviewed CT reports and intraoperative findings in advanced ovarian cancer. Even when interpreted by expert radiologists, CT imaging alone may inadequately reflect disease burden. These findings emphasise the ongoing challenges of imaging-based surgical planning and support the need for further development and validation of more accurate preoperative assessment tools.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"93 ","pages":"Article 107214"},"PeriodicalIF":1.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical radiologyPub Date : 2026-02-01Epub Date: 2025-12-09DOI: 10.1016/j.crad.2025.107205
I. del Canto , M.-P. Lopez-Lereu , J.V. Monmeneu , F.J. Chorro , V. Bodí , D. Moratal
{"title":"Assessment of remote ventricular dysfunction by cardiac magnetic resonance feature tracking strain in chronic infarction","authors":"I. del Canto , M.-P. Lopez-Lereu , J.V. Monmeneu , F.J. Chorro , V. Bodí , D. Moratal","doi":"10.1016/j.crad.2025.107205","DOIUrl":"10.1016/j.crad.2025.107205","url":null,"abstract":"<div><h3>Aim</h3><div>To quantify regional LV deformation parameters in subjects with chronic myocardial infarction (MI) by the combination of CMR feature tracking (CMR-FT) and LGE images to assess segmental myocardial function in remote myocardium and to evaluate their relationships with infarct size and post-infarction LV global function.</div></div><div><h3>Materials and Methods</h3><div>CMR-images (SSFP cine and LGE) were acquired from 34 chronic MI patients and 32 healthy volunteers included in this retrospective study. LV ejection fraction (LVEF), infarct size (IS), CMR-FT regional circumferential, radial and longitudinal strain (CS, RS, LS), time-to-peak strain (TTP-CS, TTP-RS, TTP-LS) and rotation were measured.</div></div><div><h3>Results</h3><div>CS, RS and LS were greater for remote, adjacent and border zones than for infarct areas (p<0.01); TTP-CS, TTP-RS and TTP-LS values were shorter for remote and border zones than for infarct areas (p<0.05). Maximum apical rotation was found at the border zone (p<0.05). Remote CS, RS and LS in MI were significantly lower than in healthy subjects (p<0.01). Remote CS and LS correlated with IS (CS: r=0.75, LS: r=0.82, p<0.0001) and LVEF (CS: r=-0.87, LS: r=-0.83, p<0.001). In ROC analysis for the detection of contractile dysfunction in RM, IS and LVEF performed best with AUCs of 0.98 and 0.94, showing cut-off values of 17 % and 54 %, respectively.</div></div><div><h3>Conclusions</h3><div>Quantitative assessment of LV strain and rotation provides deformation characteristics of infarct, border and remote areas in patients with chronic MI, relating contractile dysfunction in remote areas to the extent of the infarcted region, which could offer useful clinical insights into the LV remodeling process.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"93 ","pages":"Article 107205"},"PeriodicalIF":1.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical radiologyPub Date : 2026-02-01Epub Date: 2025-11-26DOI: 10.1016/j.crad.2025.107191
Y.-Y. Ye , Q. Zhang , C.H. Zeng , H.-D. Zhu , H.-M. Shen , W.-H. Liu , Y.-N. Zhang , H.-L. Hu , Z. Qin , G.-J. Teng
{"title":"Ultrasound-guided cryoablation for breast cancer ineligible for or refused surgery: a single-center experience","authors":"Y.-Y. Ye , Q. Zhang , C.H. Zeng , H.-D. Zhu , H.-M. Shen , W.-H. Liu , Y.-N. Zhang , H.-L. Hu , Z. Qin , G.-J. Teng","doi":"10.1016/j.crad.2025.107191","DOIUrl":"10.1016/j.crad.2025.107191","url":null,"abstract":"<div><h3>Aim</h3><div>To evaluate the safety and feasibility of ultrasound-guided cryoablation for breast cancer in patients ineligible for or who refused surgery.</div></div><div><h3>Materials and methods</h3><div>In this retrospective study, women with breast cancer who were ineligible for or refused surgery underwent ultrasound-guided cryoablation and adjuvant therapy, as appropriate, from April 2020 to April 2023 and were included. The primary evaluation criterion was tumor progression assessed by mRECIST on both contrast-enhanced ultrasound and dynamic contrast-enhanced magnetic resonance imaging. Pain assessment using visual analog scale, complications, and cosmetic satisfaction were also evaluated.</div></div><div><h3>Results</h3><div>Seventeen patients receiving successful cryoablation were included in the study, and 16 received adjuvant endocrine therapy. The mean age was 70 ± 9 years. The median tumor diameter was 1.79 cm (interquartile range, 0.91–3.30 cm). During a mean follow-up period of 27.8 months (range, 12–36 months), the complete response rate was 100 %. Mild pain was indicated in 17.6 % (3/17) of patients using the visual analog scale. No severe procedure-related complications were reported, and cosmetic satisfaction reached 100 %.</div></div><div><h3>Conclusion</h3><div>According to the results of the current study, ultrasound-guided cryoablation for breast cancer is a safe and feasible treatment in women who are ineligible for or refuse surgery.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"93 ","pages":"Article 107191"},"PeriodicalIF":1.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145803371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical radiologyPub Date : 2026-02-01Epub Date: 2025-12-15DOI: 10.1016/j.crad.2025.107218
M. Hattori , H. Kato , M. Kawaguchi , K. Kobayashi , T. Miyazaki , N. Watanabe , H. Nishibori , Y. Noda , F. Hyodo , M. Matsuo
{"title":"CT and MRI characteristics of ovarian mucinous tumors associated with mature teratomas","authors":"M. Hattori , H. Kato , M. Kawaguchi , K. Kobayashi , T. Miyazaki , N. Watanabe , H. Nishibori , Y. Noda , F. Hyodo , M. Matsuo","doi":"10.1016/j.crad.2025.107218","DOIUrl":"10.1016/j.crad.2025.107218","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to evaluate the CT and MRI features of ovarian mucinous tumors associated with mature teratomas.</div></div><div><h3>Materials and Methods</h3><div>The present study enrolled a total of 34 patients with histopathologically proven ovarian mucinous tumors associated with mature teratomas, including collision tumors composed of mucinous tumors and mature teratomas and mucinous tumors arising from mature teratomas. All patients underwent preoperative pelvic CT and/or MRI. Imaging findings were retrospectively reviewed.</div></div><div><h3>Results</h3><div>Histopathological diagnosis of mucinous tumors included mucinous cystadenoma in 22 patients, mucinous borderline tumor (MBT) in 10 patients, and mucinous carcinoma in two patients. The mean maximum tumor diameter was 168 mm (range, 39–314 mm). All tumors were unilateral, well-defined, predominantly cystic, and multilocular. A total of 14 tumors (41 %) had fewer than 10 loculi, while 12 tumors (35 %) had 30 or more. Fatty components were observed in 30 tumors (88 %), and 20 of 30 tumors (67 %) had multiple fatty components. On MRI, stained glass appearance was observed in 20 of 29 tumors (69 %). On CT, nodular calcifications within fatty components were observed in 12 of 21 tumors (57 %), whereas flattened calcifications within the septa of non-fatty components were observed in 7 of 21 tumors (33 %). Pseudomyxoma peritonei (PMP) was observed in three patients (9 %) with MBT.</div></div><div><h3>Conclusions</h3><div>Ovarian mucinous tumors associated with mature teratomas typically presented as large, multilocular cystic lesions with fatty components and teratoma/mucinous tumor-associated calcifications. Although PMP was uncommon, it was rarely observed in patients with MBT.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"93 ","pages":"Article 107218"},"PeriodicalIF":1.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145941280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical radiologyPub Date : 2026-02-01Epub Date: 2025-12-01DOI: 10.1016/j.crad.2025.107193
M. Singhal , A. Sharma , G. Sri , H. Bhatia , H. Gupta , H. Singh
{"title":"Utility of CT angiography in the comprehensive assessment of sinus of Valsalva aneurysms","authors":"M. Singhal , A. Sharma , G. Sri , H. Bhatia , H. Gupta , H. Singh","doi":"10.1016/j.crad.2025.107193","DOIUrl":"10.1016/j.crad.2025.107193","url":null,"abstract":"<div><h3>Aim</h3><div>To report imaging findings of Sinus of Valsalva (SOV) aneurysms (SOVAs), their complications, and additional vascular/cardiac findings on CT angiography.</div></div><div><h3>Materials and Methods</h3><div>A retrospective review of 12,568 CT coronary angiograms and aortograms (electrocardiographic (ECG) gated and non-gated) between December 2021 and December 2024, and acquired on a 192 dual-source/energy CT scanner, was performed. Patients diagnosed with SOVAs were recorded and analyzed in detail.</div></div><div><h3>Results</h3><div>Among the 12,568 cases, 34 cases had SOVAs. There were 29 males and 5 females, with a mean age of 37.38 (Range, 13–67 years). The incidence of SOVAs was 0.27 %. Twenty-eight patients (82 %) had congenital aneurysms, while six patients (18 %) had acquired aneurysms. Fourteen patients (41.3 %) were clinically silent, while the remaining 20 patients were symptomatic, of whom 13 had ruptured SOVAs. Breathlessness was the most common clinical presentation, observed in 10 patients (29.4 %), followed by palpitations in 7 (20.5 %), and chest pain in 3 patients (8.8 %). On CT angiography, congenital SOVAs were diagnosed in 28 patients, and the right SOVAs were the most common (n=14). Unruptured aneurysms were more common (21 patients; 61.7 %). Of the ruptured aneurysms (n=13), type V aneurysms constituted the majority (n=5; 38 %).</div></div><div><h3>Conclusion</h3><div>SOVAs can have catastrophic presentations if not diagnosed and treated promptly. CT angiograms with current multi- or dual-source CT scanners enable the precise diagnosis of SOVAs, predict impending rupture and complications due to compression or rupture, and explicitly demonstrate their relationship with surrounding structures. This article comprehensively enumerates the imaging features of SOVAs on CT angiography.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"93 ","pages":"Article 107193"},"PeriodicalIF":1.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical radiologyPub Date : 2026-02-01Epub Date: 2025-12-15DOI: 10.1016/j.crad.2025.107200
Y. Han , Y. Wang , H. Wang , L. Yan , M. Wei , L. Zhou
{"title":"Association between deep medullary veins and grey matter volume fraction in patients with cerebral small vessel disease","authors":"Y. Han , Y. Wang , H. Wang , L. Yan , M. Wei , L. Zhou","doi":"10.1016/j.crad.2025.107200","DOIUrl":"10.1016/j.crad.2025.107200","url":null,"abstract":"<div><h3>Aim</h3><div>Cerebral small vessel disease (CSVD) is a disorder of cerebral microvessels defined by clinical presentation and imaging that affects cerebral small arteries, arterioles, capillaries, and venules. Previous studies on CSVD were mainly focused on cerebral small arteries; however, there are only a few reports on the association between deep medullary veins (DMVs) and CSVD, especially the association between the number of DMVs and one of the imaging makers of CSVD-brain atrophy. The aim of this study is to investigate the relationship between DMVs and brain atrophy using 3.0T magnetic resonance images (MRI).</div></div><div><h3>Material and Methods</h3><div>We analyzed the complete clinical and imaging data of 101 hospitalized patients diagnosed with CSVD. DMVs was identified in the periventricular area using susceptibility-weighted imaging (SWI). Brain atrophy was assessed using voxel-based morphometry (VBM) calculations of gray matter (GM), white matter (WM), and cerebrospinal fluid volume fractions.</div></div><div><h3>Results</h3><div>Our results showed that the number of DMVs was significantly correlated with GM fraction (β = 0.315, <em>P</em> = 0.019, adjusted for age, hypertension, diabetes mellitus, and WM fraction). We also found that with increase in CSVD burden, there was no statistically significant association between the number of DMVs and GM fraction (β = 0.071, <em>P</em> = 0.688, adjusted for age, hypertension, diabetes mellitus, and WM fraction).</div></div><div><h3>Conclusion</h3><div>Our results provide evidence that fewer DMVs are associated with a smaller GM fraction in patients with a low burden of CSVD (β = 0.604, <em>P</em> = 0.008, adjusted for age, hypertension, diabetes mellitus, and WM fraction), while the number of DMVs is associated with brain atrophy and the progression of CSVD.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"93 ","pages":"Article 107200"},"PeriodicalIF":1.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical radiologyPub Date : 2026-02-01Epub Date: 2025-12-06DOI: 10.1016/j.crad.2025.107204
T. Truneh , D.A. Steel , K. Hawtin , J.M. Young , S.C. Shelmerdine
{"title":"Preparing for your radiology future with AI: reflections from experience","authors":"T. Truneh , D.A. Steel , K. Hawtin , J.M. Young , S.C. Shelmerdine","doi":"10.1016/j.crad.2025.107204","DOIUrl":"10.1016/j.crad.2025.107204","url":null,"abstract":"","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"93 ","pages":"Article 107204"},"PeriodicalIF":1.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical radiologyPub Date : 2026-02-01Epub Date: 2025-12-11DOI: 10.1016/j.crad.2025.107208
S. Aydın , N. Yurttutan , B. Kızıldağ , İnan Korkmaz , B.Ç. Peköz , S. Karazincir , M.R. Onur
{"title":"Lessons learned from the 2023 Türkiye twin earthquakes: how radiology facilities can respond to disasters","authors":"S. Aydın , N. Yurttutan , B. Kızıldağ , İnan Korkmaz , B.Ç. Peköz , S. Karazincir , M.R. Onur","doi":"10.1016/j.crad.2025.107208","DOIUrl":"10.1016/j.crad.2025.107208","url":null,"abstract":"<div><div>On 6 February 2023, back-to-back earthquakes (Mw 7.7 and 7.6) in southeastern Türkiye produced a prolonged mass-casualty incident, placing heavy demands on radiology services nationwide. Operational and clinical lessons were derived from frontline experience to guide emergency imaging under disaster conditions. Surge rostering and rapid staff redistribution were implemented; point-of-care ultrasound was employed for damage-control triage; and “CT-first” pathways were adopted for polytrauma. Workflow continuity during PACS/network outages was maintained with paper logs, downtime order sets, and standardized critical findings phrasing. Disaster teleradiology was activated through streamlined credentialing and ID-agnostic reporting, enabling rapid capacity expansion and support for hospitals beyond the epicentral region. Dominant injury patterns observed were crush injury with acute compartment syndrome; traumatic brain injury; chest trauma with sequential rib fractures, pulmonary contusion and pneumothorax; lumbar-predominant spinal fractures; and pelvic and long-bone injuries. Imaging correlates of rhabdomyolysis and non-lethal pneumomediastinum compatible with the Macklin effect are summarized. Protocol adaptations that preserved throughput and safety included abbreviated, low-dose trauma CT; cautious contrast use in renally vulnerable patients; and corridor-based scanner prioritisation during overflow. On the basis of these observations, a radiology preparedness bundle is presented: redundant power and IT failover; predefined modality-prioritisation matrices; caches of portable US/X-ray for secondary triage; streamlined trauma CT checklists; templated reports that foreground immediate actions; and interoperable teleradiology hooks that can be switched on rapidly. These measures are transferable to earthquakes and other mass-casualty events, sustaining diagnostic capacity, communication, and team alignment under extreme constraints.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"93 ","pages":"Article 107208"},"PeriodicalIF":1.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145941301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical radiologyPub Date : 2026-02-01Epub Date: 2025-10-07DOI: 10.1016/j.crad.2025.107114
Y. Diao , H. Liang , Y. Wang , L. Hang , L. Fang , H. Qu , H. Sun , W. Li , G. Jiang
{"title":"Exploring the diagnostic value of dynamic contrast-enhanced and diffusion tensor imaging of intratumoural and peritumoural high-grade gliomas for distinguishing treatment response from tumour progression","authors":"Y. Diao , H. Liang , Y. Wang , L. Hang , L. Fang , H. Qu , H. Sun , W. Li , G. Jiang","doi":"10.1016/j.crad.2025.107114","DOIUrl":"10.1016/j.crad.2025.107114","url":null,"abstract":"<div><h3>AIM</h3><div>Accurate differentiation true true progression (TP) and treatment response (TR) in high-grade gliomas (HGGs) remains challenging due to confounding alterations in tumour parenchymal areas. Evaluation of non-enhancing peritumoural regions (NEPTRs) plays a prominent role. This study aimed to assess diagnostic accuracy in distinguishing TP from TR by quantifying perfusion and diffusion differences in NEPTRs imaged with dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusion tensor imaging (DTI).</div></div><div><h3>MATERIALS AND METHODS</h3><div>Patients who had newly enhanced lesions or had developed enhanced lesions were retrospectively enrolled. All patients had undergone conventional imaging sequences, DTI, and DCE. Histopathological diagnosis or longitudinal clinical and imaging follow-up over 6 months was used to distinguish TP from TR. Volume transfer contrast (Ktrans), extravascular extracellular volume fraction (Ve), initial area under the time concentration curve (iAUC), fractional anisotropy (FA), and apparent diffusion coefficient (ADC) were measured in enhanced lesions and NEPTRs. Student’s t-tests and receiver operating characteristic (ROC) curves were constructed to evaluate the diagnostic performance.</div></div><div><h3>RESULTS</h3><div>TP lesions displayed higher Ktrans, Ve, and iAUC and lower FA and ADC values in the enhanced lesions. Moreover, significantly higher Ktrans and lower FA values were found in NEPTRs associated with TP. The Ktrans from DCE of enhanced lesions and the FA from DTI of NEPTRs showed high diagnostic efficacies of 0.875 and 0.861, respectively. Notably, the area under the ROC curve of Ktrans in NEPTRs reached 0.831. The combined diagnostic performance of the three parameters reached 0.983, with 96.7% sensitivity and 92.9% specificity.</div></div><div><h3>CONCLUSION</h3><div>By quantifying perfusion and diffusion in enhanced lesions and NEPTRs, DCE in combination with DTI imaging can distinguish TP from TR.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"93 ","pages":"Article 107114"},"PeriodicalIF":1.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145965471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical radiologyPub Date : 2026-02-01Epub Date: 2025-11-26DOI: 10.1016/j.crad.2025.107192
R. Castro-Zunti , Y.M. Han , K.Y. Kim , A. Vardhan , D.E. Lee , E.S. Ha , Y. Choi , H.S. Chae , G.Y. Jin , S-b. Ko
{"title":"An accurate, straightforward computer vision algorithm for optimal tumor-feeding visualization in cone-beam computed tomography hepatic arteriography: A preliminary study","authors":"R. Castro-Zunti , Y.M. Han , K.Y. Kim , A. Vardhan , D.E. Lee , E.S. Ha , Y. Choi , H.S. Chae , G.Y. Jin , S-b. Ko","doi":"10.1016/j.crad.2025.107192","DOIUrl":"10.1016/j.crad.2025.107192","url":null,"abstract":"<div><h3>Aim</h3><div>Although standardized 3D volume rendering techniques (VRT) and embolization guidance visualize and identify tumor-feeding arteries, current vessel tracking software lacks automatic angle recommendations. This forces an operator, e.g. an interventional radiologist, to leave an ongoing procedure to manually manipulate the system and find the best angle for each feeding vessel—requiring time-consuming re-scrubbing. We propose a computer vision algorithm that suggests a rotation/angle in the VRT where a tumor-feeding artery's view is maximized. We focus on hepatocellular carcinoma.</div></div><div><h3>Methods</h3><div>Our algorithm accepts a series of post-embolization guidance frames extracted from the 3D VRT; the VRT is rotated in 5° intervals from, e.g., ±15°, fixing one axis (e.g. CRAN/CAUD) and rotating the other (e.g. LAO/RAO). Our algorithm segments the embolization guidance line and recommends 4 views/angles by maximizing the features of line length (contour area) and convex hull area. We developed/iterated our algorithm using 19 patient cases and feedback from various experts.</div></div><div><h3>Results</h3><div>Over a 50-patient internal validation set, according to an interventional radiologist with 33 years of experience, a view/angle sufficient for the embolization task was always present among the top-4 views/angles suggested by our algorithm (100% retrieval relevance).</div></div><div><h3>Conclusion</h3><div>Sufficient view/angle selection for hepatic artery embolization can be achieved using traditional computer vision. Our technique is much faster and more explainable than deep learning approaches, and could greatly improve radiologists' procedural efficiency. We recommend conducting a larger study with more patients and further technical iteration.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"93 ","pages":"Article 107192"},"PeriodicalIF":1.9,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}