Clinical Neurophysiology最新文献_第6页

When sleep turns violent: coexisting sleep-related hypermotor epilepsy and somnambulism documented by polysomnography 当睡眠变得暴力：多导睡眠图记录的与睡眠相关的多动性癫痫和梦游症共存

IF 3.6 3区医学

Clinical Neurophysiology Pub Date : 2025-08-08 DOI: 10.1016/j.clinph.2025.2110965

Ceren Alis, Tuba Cerrahoglu Sirin

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Brain-breathing interaction during MRI-related anxiety 核磁共振相关焦虑期间脑呼吸的相互作用

IF 3.6 3区医学

Clinical Neurophysiology Pub Date : 2025-08-07 DOI: 10.1016/j.clinph.2025.2110961

Gert Pfurtscheller , Beate Rassler , Maciej Kaminski , Gerhard Schwarz , Alexandre Andrade , Klaus Pfurtscheller , Wolfgang Klimesch

{"title":"Brain-breathing interaction during MRI-related anxiety","authors":"Gert Pfurtscheller , Beate Rassler , Maciej Kaminski , Gerhard Schwarz , Alexandre Andrade , Klaus Pfurtscheller , Wolfgang Klimesch","doi":"10.1016/j.clinph.2025.2110961","DOIUrl":"10.1016/j.clinph.2025.2110961","url":null,"abstract":"<div><div>Nasal breathing can entrain fast oscillations in the prefrontal cortex and limbic systems, as experiments with rodents and intracranial EEG recordings in patients have shown. Recently, it was demonstrated that the activity of the amygdala and hippocampus can also be studied non-invasively, using functional magnetic resonance imaging (fMRI). When simultaneously recording BOLD signals, respiration and cardiac RR interval (RRI) time courses, and applying a multivariate autoregressive (MVAR) model combined with Granger causality analysis, it becomes possible to assess directed coupling, or information flow, between brain structures and the body organs (i.e., heart and lung).</div><div>Klimesch’s binary hierarchy model links fast neural oscillations in the gamma and beta range with medium-range rhythms of the heart and respiration, as well as with infra-slow BOLD oscillations (<0.1 Hz), all aimed to minimize the brain’s energy demands. This model predicts three preferred breathing frequencies, 0.32 Hz, 0.16 Hz, and 0.08 Hz, as well as an infra-slow oscillation (ISO) at 0.02 Hz. Remarkably, the preferred breathing frequency of 0.32 Hz (∼20 cycles per minute) appears to be a universal marker of anxiety, which is observed in patients and healthy participants during MRI sessions.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"178 ","pages":"Article 2110961"},"PeriodicalIF":3.6,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144851988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seizures and breathing: lessons from peri-ictal respiratory disturbances 癫痫和呼吸：周周呼吸障碍的教训

IF 3.6 3区医学

Clinical Neurophysiology Pub Date : 2025-08-06 DOI: 10.1016/j.clinph.2025.2110962

Elisa Micalizzi , Alice Ballerini , Nuria Lacuey , Leandra Giunta , Flavio Villani , Stefano Meletti , Anna Elisabetta Vaudano

{"title":"Seizures and breathing: lessons from peri-ictal respiratory disturbances","authors":"Elisa Micalizzi , Alice Ballerini , Nuria Lacuey , Leandra Giunta , Flavio Villani , Stefano Meletti , Anna Elisabetta Vaudano","doi":"10.1016/j.clinph.2025.2110962","DOIUrl":"10.1016/j.clinph.2025.2110962","url":null,"abstract":"<div><div>Breathing can be disrupted by pathological neurological conditions, such as seizures. Ictal respiratory changes comprise central or obstructive apnea, tachypnea, bradypnea, hypoventilation, and hypoxemia. Ictal central apnea (ICA) has been described in association with focal seizures, especially of temporal origin, occurring in 36%–40% of ictal events. Longer ICA duration typically produces hypoxemia, being observed in 33–41% of cases. PCCA (post-convulsive central apnea) has been described in relation to generalized seizures, suggesting brainstem dysfunction following a generalized tonic-clonic seizure (GTC). Growing interest in <em>peri</em>-ictal respiratory disturbances stems from their potential association with sudden unexpected death in epilepsy (SUDEP), the leading cause of mortality in people with epilepsy (PWE). Recent research has highlighted <em>peri</em>-ictal respiratory symptoms as a key factor in SUDEP risk. Given the expanding body of evidence, a comprehensive review is needed to synthesize findings from experimental and clinical studies. Recent intracranial EEG and neuroimaging research has provided new insights into the neurophysiological, structural, and functional correlates of ICA and PCCA, as well as their possible link with SUDEP. This narrative review explores the electroclinical features and pathophysiology of <em>peri</em>-ictal respiratory disturbances, summarizes current neuroimaging data, and discusses their implications for SUDEP risk and potential treatment strategies.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"178 ","pages":"Article 2110962"},"PeriodicalIF":3.6,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144809472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of the left primary motor cortex in apraxia 左初级运动皮层在失用症中的作用

IF 3.6 3区医学

Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110847

Ksenia Perlova , Claudia Schmidt , Gereon R. Fink , Peter H. Weiß-Blankenhorn

引用次数: 0

Functional network alteration within the sensorimotor system in degenerative cervical myelopathy 退行性脊髓型颈椎病感觉运动系统的功能网络改变

IF 3.6 3区医学

Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110852

Leonie Hams , Charlotte Nettekoven , Phillip Keil , Christoph Kabbasch , Anna Zdunczyk , Peter Vajkoczy , Roland Goldbrunner , Carolin Weiß Lucas

引用次数: 0

Improvements in pain and disability contribute to improved quality of life after inebilizumab treatment in attack-free neuromyelitis optica spectrum disorder (NMOSD) participants 无发作性视谱神经脊髓炎（NMOSD）患者接受依比利珠单抗治疗后，疼痛和残疾的改善有助于改善生活质量

IF 3.6 3区医学

Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110843

Orhan Aktas , Friedemann Paul , Douglas K. Sato , Jodie M. Burton , Mike A. Smith , William A. Rees , Kristina R. Patterson , Bruce Cree

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Thalamic regulation of reinforcement strategy switching across prefrontal-striatal networks 前额叶-纹状体网络强化策略转换的丘脑调节

IF 3.6 3区医学

Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110844

Burkhard Pleger , Bin Wang , Norman Lam , Shumei Li , Ralf Wimmer , Liu Mengxing , Pedro Paz-Alonso , Mike Halassa

引用次数: 0

Deep brain stimulation as a determinant of cognitive outcome in GBA-Parkinson’s disease? 脑深部电刺激是gba -帕金森病认知预后的决定因素？

IF 3.6 3区医学

Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110862

Moritz Loeffler , Philipp Klocke , Idil Cebi , Isabel Wurster , Stefanie Lerche , Thomas Gasser , Alireza Gharabaghi , Kathrin Brockmann , Daniel Weiß

引用次数: 0

Exploring the structural reserve: structural connectivity in motor network protects from detrimental weak state of motor network connectivity after stroke 探索结构储备：脑卒中后运动网络的结构连通性可防止运动网络的弱连接状态

IF 3.6 3区医学

Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.2110870

Jonas Günther , Theresa Paul , Lukas Hensel , Valerie Wiemer , Anna Bonkhoff , Matthew Cieslak , Caroline Tscherpel , Christian Grefkes-Hermann , Scott Grafton , Gereon R. Fink , Lukas Jan Volz

引用次数: 0

High-frequency oscillations in neonatal EEG and their association with epilepsy 新生儿脑电图高频振荡及其与癫痫的关系。

IF 3.6 3区医学

Clinical Neurophysiology Pub Date : 2025-08-01 DOI: 10.1016/j.clinph.2025.03.024

Sini Hautala , Kirsi Mikkonen , Päivi Nevalainen

{"title":"High-frequency oscillations in neonatal EEG and their association with epilepsy","authors":"Sini Hautala , Kirsi Mikkonen , Päivi Nevalainen","doi":"10.1016/j.clinph.2025.03.024","DOIUrl":"10.1016/j.clinph.2025.03.024","url":null,"abstract":"<div><h3>Objective</h3><div>We assessed high-frequency oscillations (HFOs) in neonatal EEG hypothesizing that HFOs would be prevalent in neonates with prevailing or forthcoming severe epilepsy, fewer in those with benign epilepsy or acute provoked seizures, and absent in healthy neonates.</div></div><div><h3>Methods</h3><div>From a population-derived EEG database, we identified neonates with neonatal-onset epilepsy, chronic brain disease, acute stroke, perinatal hypoxic ischemic encephalopathy, acute brain infection, or no neurological diagnoses. We marked sleep stages, seizures, and HFOs manually, and evaluated outcome from medical records.</div></div><div><h3>Results</h3><div>HFOs were detected in 29/98 (30 %) neonates, of whom 10 had ictal (median rate 0.53/min, range 0.07–6.41/min) and 24 had nonictal HFOs (median rate 0.20/min, range 0.01–20.99/min). Nonictal HFO occurrence and rate were significantly i) higher in neonates with neonatal-onset developmental and epileptic encephalopathy (DEE) than most other diagnostic groups, and ii) higher in neonates that later developed infantile-onset DEE (p < 0.05) than those surviving without DEE. Ictal HFOs were common during acute provoked seizures and were not linked with epilepsy.</div></div><div><h3>Conclusions</h3><div>Neonatal nonictal HFOs were associated with prevailing or forthcoming early-onset DEE.</div></div><div><h3>Significance</h3><div>Our data support the hypotheses that neonatal scalp HFOs are i) pathological, ii) associated with epilepsy severity, and iii) a marker of epileptogenesis.</div></div>","PeriodicalId":10671,"journal":{"name":"Clinical Neurophysiology","volume":"176 ","pages":"Article 2010697"},"PeriodicalIF":3.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143751492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0