Contemporary Clinical Dentistry最新文献

{"title":"CD34 Angiogenesis Marker in Oral Squamous Cell Carcinoma: An Immunohistochemical Study.","authors":"Vijayalaxmi, Sunil S Mishra, N C Sangamesh","doi":"10.4103/ccd.ccd_545_24","DOIUrl":"10.4103/ccd.ccd_545_24","url":null,"abstract":"<p><strong>Background: </strong>Angiogenesis is recognized as a predominant factor for tumor growth and metastasis. Use of biomarkers to target tumor holds a promising treatment strategy and to assess prognosis.</p><p><strong>Objectives: </strong>To assess angiogenic activity by analyzing CD34 microvascular density (MVD) count in different histologic grades of oral squamous cell carcinoma (OSCC).</p><p><strong>Materials and methods: </strong>Sixty archival samples are categorized in four groups. Immunohistochemical method with anti-CD34 was used for analyzing MVD.</p><p><strong>Results: </strong>The mean count of MVD is higher in OSCC than in normal mucosa and also significant among different histologic grades. Highly significant correlation is observed among different groups of OSCC samples.</p><p><strong>Conclusion: </strong>CD34 shows a promising result in OSCC.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"16 2","pages":"124-127"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12342217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ameloblastic Fibroma: A Case Report of a Rare Presentation Illustrating a Diagnostic Challenge.","authors":"Carlos Estrela, Tatiana Furlan, Artur A Carvalhosa, Nicole T Cirilo, Neumara Marcon, Mike Bueno, Eneida F Vêncio, Brunno Santos De Freitas Silva","doi":"10.4103/ccd.ccd_291_24","DOIUrl":"10.4103/ccd.ccd_291_24","url":null,"abstract":"<p><p>This case report emphasizes the diagnostic role of cone-beam computed tomography (CBCT) in identifying a rare pediatric case of ameloblastic fibroma (AF), comprising approximately 2% of odontogenic tumors. The 10-year-old patient initially presented with painless left mandibular posterior gingival swelling, resembling radicular or dentigerous cysts in clinical and conventional radiographic assessments. However, CBCT revealed a distinct periapical radiolucency linked to deciduous molar roots and an unerupted premolar, exposing mandibular lingual plate thinning and buccal plate disruption. The lesion extended beyond the unerupted premolar's enamel-cementum junction, suggesting an odontogenic tumor. Subsequent biopsy and histopathological examination confirmed AF. CBCT played a pivotal role in evaluating the lesion's interaction with surrounding bone structures, guiding treatment decisions, and contributing to an accurate diagnosis. Successful lesion excision, deciduous tooth extraction, and a disease-free year-long follow-up underscore the significance of enhancing diagnostic precision and managing uncommon odontogenic pathologies like AF.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"16 2","pages":"136-139"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12338470/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cone-beam Computed Tomography Analysis and Rehabilitation of a Rare Case of Bilateral Taurodontism.","authors":"Monika Nandan, Harmeet Singh, Gautam Khatak, Akshdeep Singh","doi":"10.4103/ccd.ccd_280_25","DOIUrl":"10.4103/ccd.ccd_280_25","url":null,"abstract":"<p><p>Taurodontism is an anomaly affecting the morphology and anatomy of the tooth, leading to apical displacement of the furcation in multirooted teeth. This leads to an enlarged body of the tooth and reduced size of the root. Taurodontism is a rare dental finding. The endodontic management of such teeth is challenging because of their altered morphology, presence of extra canals, and enlarged pulp chamber. A cone-beam computed tomography is recommended to analyze the root canal morphology. Endocrowns can be used for prosthetic rehabilitation as they utilize retention from the elongated pulp chamber. This case presents a rare occurrence of bilateral maxillary and mandibular teeth with taurodontism. Five out of eight teeth were hypertaurodont, which is a very rare phenomenon. Two teeth were root canal treated followed by rehabilitation with endocrown.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"16 2","pages":"140-143"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12338478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unmasking Plummer-Vinson Syndrome: A Rare Case Report.","authors":"B Radhika, Aswini Sekar, Priyanka Gandhi","doi":"10.4103/ccd.ccd_448_24","DOIUrl":"10.4103/ccd.ccd_448_24","url":null,"abstract":"<p><p>This article highlights a unique case of Plummer-Vinson syndrome (PVS), also known as Paterson Brown-Kelly Syndrome. PVS is associated with a triad of symptoms, including microcytic hypochromic anemia, esophageal strictures, and dysphagia. It is commonly found in middle-aged women, particularly in the fourth and fifth decades of life, and is rarely reported in males. We present the case of a 49-year-old female patient who exhibited the classic symptoms of PVS. Given that PVS is a precancerous condition with a high potential for malignancy, early diagnosis is crucial for a better prognosis. Surveillance endoscopy and barium swallow test are recommended for monitoring. Iron repletion often improves dysphagia, and in some cases, esophageal dilatation is used to provide symptomatic relief. The mutual interaction of systemic and oral health is often underestimated, especially by patients in developing countries. Therefore, this report emphasizes the importance of thorough medical history taking and its relevance to dental health and treatment.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"16 2","pages":"132-135"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12338457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Actinomycotic Osteomyelitis in the Maxilla: A Rare Case Report of Postdengue Complication in Diabetic Patients.","authors":"Prashanthi Reddy, Ajay Parihar, Sujata Tosh, Arun Dev Sharma, Saloni Agrawal, Yashika Kewalramani","doi":"10.4103/ccd.ccd_215_25","DOIUrl":"10.4103/ccd.ccd_215_25","url":null,"abstract":"<p><p>Actinomycotic osteomyelitis in the maxilla is a rare complication, particularly in diabetic patients following dengue infection. Actinomycosis, caused by <i>Actinomyces israelii</i>, typically arises in immunocompromised hosts, with dengue-induced immune dysregulation and diabetes contributing to its pathogenesis. This case report describes a 42-year-old diabetic male presenting with oroantral communication, loose posterior maxillary teeth, and persistent pus discharge 20 days postdengue. Imaging revealed bone erosion, and histopathology confirmed actinomycosis. The patient underwent partial maxillectomy with antibiotic therapy, leading to full recovery within 6 months. This case emphasizes the importance of early diagnosis and tailored treatment in managing rare bacterial infections in vulnerable populations.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"16 2","pages":"144-147"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12338455/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144834387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orofacial Proprioceptive Stimulation Therapy with a Palatal Memory Plate in a Baby with Down Syndrome - 2-year Follow-up Case Report.","authors":"Fábia Ulisses Peixoto Esmeraldo, Natalia Victoria Del Carmen Guerra Trujillo, Sirannara Paulino Gomes Morbeck, Lívia Lima Xavier, Rebeca Bastos Vasconcelos Marinho, Isabella Fernandes Carvalho","doi":"10.4103/ccd.ccd_500_24","DOIUrl":"https://doi.org/10.4103/ccd.ccd_500_24","url":null,"abstract":"<p><p>Children with Down syndrome (DS) have oral manifestations, such as hypotonia of the perioral muscles, inadequate lip seal, and tongue posture changes, which affect the development of the stomatognathic system. The palatal memory plate (PMP) is an early proprioceptive stimulation therapy that aims to improve tongue posture, promote proper lip sealing, and contribute to oral balance. This study reports the treatment of PMP in a 2-month-old baby with DS. Early intervention with PMP exhibited satisfactory results, improving hypotonia, tongue posture, and lip seal even after 2 years of treatment. This improvement was enhanced by a multidisciplinary speech therapy approach to orofacial stimulation with the active participation of caregivers. Thus, the training of qualified professionals with knowledge of the specific characteristics of patients with DS is essential for a comprehensive and systematic approach to promoting their health.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"16 1","pages":"69-72"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12014009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-modal Restorative Endodontic Management to Rehabilitate and Salvage a Tooth with External Cervical Resorption and Iatrogenic Over Enlarged Root Canal with Widened Apex.","authors":"Gopal Chandra Sanyal, A R Vivekananda Pai, S Harishma, Riddhi Kotecha","doi":"10.4103/ccd.ccd_501_24","DOIUrl":"https://doi.org/10.4103/ccd.ccd_501_24","url":null,"abstract":"<p><p>The presence of both a pathologic external cervical resorption (ECR) and an iatrogenic over-enlarged root canal with a widened apex can significantly compromise the structural integrity of a tooth. Furthermore, regular restorative-endodontic management of the involved tooth poses many procedural challenges and difficulties. However, a multi-modal approach involving nonsurgical and surgical procedures with the application of advances in endodontics can help to manage and salvage such a tooth. This article aims to report on a case of multi-modal management with the application of cone-beam computed tomography, micro-endodontics, bioactive and biomimetic materials, and monobloc effect to manage and structurally rehabilitate and reinforce a tooth affected by both ECR and over enlarged canal with a widened apex. This multi-modal approach was applied with nonsurgical and surgical treatments to restoratively and endodontically manage the affected tooth. Clinical and radiographic follow-up of the tooth was uneventful and showed satisfactory and favorable outcomes.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"16 1","pages":"61-64"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12014007/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Study of Four Rotary Endodontic File Systems: Assessing Canal Transportation and Centering Ability using Cone-beam Computed Tomography.","authors":"Ajay Chhabra, K P Ramya, B Saravana Prathap, Bhavana Murjani, Priyanka Yadav","doi":"10.4103/ccd.ccd_379_24","DOIUrl":"https://doi.org/10.4103/ccd.ccd_379_24","url":null,"abstract":"<p><strong>Aim: </strong>The aim of this study was to compare the canal transportation and centering ability of four rotary endodontic file systems using cone-beam computed tomography (CBCT).</p><p><strong>Methodology: </strong>This was an <i>in vitro</i> study where 40 extracted single-rooted single canal human premolar teeth were used. CBCT scans of all the teeth were taken before instrumentation and were randomly divided into four groups, with 10 samples in each; Group I-Protaper Next (PN), Group II-Protaper Gold (PG), Group III-Neo Endo Flex (NE), and Group IV-Gen Endo (GE). After cleaning and shaping, the canals with respective file systems postinstrumentation scans were performed, and the two scans were compared to determine canal transportation and centering ability at 3, 6, and 9 mm, from the apex.</p><p><strong>Results: </strong>Statistical analysis was performed using the Kruskal-Wallis test where the results showed no statistically significant difference among the tested groups in canal transportation and centering ability at the coronal, middle, and cervical third (<i>P</i> > 0.05).</p><p><strong>Conclusion: </strong>Under the conditions of the <i>in vitro</i> study PN, PG, NE, and GE file systems exhibited comparable behavior in terms of canal transportation and centering ability, observational data suggested that Group 1 (PN) and Group 4 (GE) demonstrated superior centering ability and reduced canal transportation.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"16 1","pages":"44-48"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12014003/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis and Management of Natal Tooth Secondary to Beckwith-Wiedemann Syndrome in a 25-day-old Infant: A Rare Case Report.","authors":"G Divya Lakshmi, H A Amitha, G Suma, N S Priya","doi":"10.4103/ccd.ccd_142_24","DOIUrl":"https://doi.org/10.4103/ccd.ccd_142_24","url":null,"abstract":"<p><p>Beckwith-Wiedemann syndrome (BWS) is a rare genetic disorder characterized by somatic overgrowth and an increased predisposition to various medical conditions, including neoplasms. This case report presents a 25-day-old male infant with BWS exhibiting macroglossia, hepatosplenomegaly, hyperinsulinemic hypoglycemia, gum hypertrophy, and cystic lesions in the maxillary arch, prompting a multidisciplinary collaboration of a pediatrician, pedodontist, oral surgeon, and an oral pathologist. The patient also presented with Hebling's Class III natal tooth. Following all the precautions, the natal tooth was extracted under local anesthesia. This case report stands out for documenting the presence of a natal tooth in a diagnosed case of BWS for the first time, contributing to the understanding of oral manifestations in rare genetic syndromes and underscoring the need for timely intervention and comprehensive medical care in managing this complex genetic syndrome.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"16 1","pages":"56-60"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12014001/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Evaluation between Self-Assembling Peptide P11-4 and ACP CPP in Enamel Remineralization Post Er: YAG Laser Irradiation - A Confocal Laser Scanning Microscopic Study.","authors":"H Bhargavi, Savitha B Naik, N Kiran Kumar, Seema Merwade, Biji Brigit, Shriya Sunil Bhumralkar, Ashwini Suresh Kadam, H S Preetham","doi":"10.4103/ccd.ccd_311_24","DOIUrl":"https://doi.org/10.4103/ccd.ccd_311_24","url":null,"abstract":"<p><strong>Background: </strong>The focus in caries management has shifted to early detection of caries lesions and targeted noninvasive management of incipient lesions using novel remineralizing agents.</p><p><strong>Aim and objective: </strong>The study aimed to compare and evaluate the remineralization potential of self-assembling peptide (Curodont repair) and ACP-CPP (MI varnish) on human enamel and to compare and evaluate the effect of Er: YAG laser on their remineralizing potential.</p><p><strong>Materials and methods: </strong>A total of 36 teeth were divided into four experimental groups after etching all the specimens with 36% phosphoric acid to create an artificial white spot lesion (WSL). Demineralization depth was analyzed using confocal laser scanning microscope and samples were divided into four groups; Group 1 and Group 2 specimens were treated with remineralizing agents ACP-CPP and self-assembling peptide, whereas Group 3 was treated with Er: YAG laser and ACP-CPP and Group 4 specimens received Er: YAG laser and self-assembling peptide. The remineralizing pastes were applied with applicator tips and left on for 2 min, laser activation was done with an energy of 100 mJ, frequency of 10 Hz, and with the use of minimum air/water spray following which the samples were thoroughly washed with deionized water and stored in artificial saliva. The same procedure is carried out for 14 days. After the procedure, all the enamel samples were assessed for confocal laser scanning microscopy.</p><p><strong>Results: </strong>The depth of remineralization was significantly increased in all four groups as compared to the depth of demineralization, but the mean difference was significantly highest in Group 4, Group 3, and Group 2, and least in Group 1.</p><p><strong>Conclusion: </strong>In this study, the most effective method for increasing the remineralization of the WSLs was the simultaneous use of the Er: YAG laser and self-assembling peptide together. The better results observed in Group 4 might be due to the synergistic effect of laser and self-assembling peptide.</p>","PeriodicalId":10632,"journal":{"name":"Contemporary Clinical Dentistry","volume":"16 1","pages":"3-9"},"PeriodicalIF":0.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12014000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}