{"title":"Letter to the editor – “Adherence to a healthful plant-based diet and risk of mortality among individuals with chronic kidney disease: A prospective cohort study”","authors":"Bin Niu","doi":"10.1016/j.clnu.2024.11.034","DOIUrl":"10.1016/j.clnu.2024.11.034","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"44 ","pages":"Pages 14-15"},"PeriodicalIF":6.6,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor-“Reply-letter to the editor”","authors":"Yoshiyasu Takefuji","doi":"10.1016/j.clnu.2024.11.031","DOIUrl":"10.1016/j.clnu.2024.11.031","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"44 ","pages":"Pages 7-8"},"PeriodicalIF":6.6,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142726576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiude Li , Meiling Li , Jing Cheng, Shixia Guan, Lili Hou, Shuang Zu, Le Yang, Hanhan Wu, Huixian Li, Yunshan Fan, Bao Zhang
{"title":"“Reply - Letter to the editor” - “Association of healthy and unhealthy plant-based diets with telomere length”","authors":"Xiude Li , Meiling Li , Jing Cheng, Shixia Guan, Lili Hou, Shuang Zu, Le Yang, Hanhan Wu, Huixian Li, Yunshan Fan, Bao Zhang","doi":"10.1016/j.clnu.2024.11.032","DOIUrl":"10.1016/j.clnu.2024.11.032","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"44 ","pages":"Pages 9-11"},"PeriodicalIF":6.6,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142738742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the editor – “Association of healthy and unhealthy plant-based diets with telomere length”","authors":"Mo-Yao Tan, Ping Zhang, Ming Gao","doi":"10.1016/j.clnu.2024.11.030","DOIUrl":"10.1016/j.clnu.2024.11.030","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"44 ","pages":"Pages 12-13"},"PeriodicalIF":6.6,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adrianna Greco , Jo-Anna B. Baxter , Kathryn Walton , Susanne Aufreiter , Michael A. Pitino , Carleigh Jenkins , Samantha Ismail , Alex Kiss , Debbie Stone , Sharon L. Unger , Deborah L. O'Connor
{"title":"Vitamin B12 concentrations vary greatly in milk donated to a large provincial milk bank, and are influenced by supplementation and parity","authors":"Adrianna Greco , Jo-Anna B. Baxter , Kathryn Walton , Susanne Aufreiter , Michael A. Pitino , Carleigh Jenkins , Samantha Ismail , Alex Kiss , Debbie Stone , Sharon L. Unger , Deborah L. O'Connor","doi":"10.1016/j.clnu.2024.11.027","DOIUrl":"10.1016/j.clnu.2024.11.027","url":null,"abstract":"<div><h3>Background & aims</h3><div>Feeding parent's milk with supplemental donor milk (DM) is the optimal way to feed very low birth weight (VLBW) infants instead of formula; however, suboptimal neurodevelopment persists. This is believed due, in part, to suboptimal nutrition. Given vitamin B12's role in neurodevelopment and increased adoption of plant-based diets among females of child-bearing age, we aimed to determine the adequacy of vitamin B12 in DM (n = 380 donors) and associated donor characteristics.</div></div><div><h3>Methods</h3><div>Vitamin B12 was measured in consecutive raw DM donations received at the milk bank from March 2020–2021 using a validated competitive chemiluminescent enzyme immunoassay (IMMULITE 2000, Siemens). Donor characteristics were obtained from screening records and associations with milk vitamin B12 concentrations explored using a generalized additive model.</div></div><div><h3>Results</h3><div>Donors were 32 ± 4 years old (mean ± SD), and DM was expressed 98 ± 85 days postpartum. Vitamin B12 concentrations in DM had a median (25th, 75th percentile) of 232 (149, 373) pmol/L; 64 % had concentrations <310 pmol/L (common cut-off for inadequacy in healthy term-born infants). In a multivariable analysis, donors consuming a vitamin B12-containing supplement had higher DM vitamin B12 (β ± SE: 80.3 ± 25.4 pmol/L; p = 0.020) compared to those not taking a supplement. Primiparous donors had higher DM vitamin B12 than multiparous donors (36.7 ± 18.2 pmol/L greater; p = 0.044). No associations were observed for other donor characteristics.</div></div><div><h3>Conclusion</h3><div>Milk donated to a large human milk bank showed evidence of suboptimal vitamin B12; levels were associated with both donor vitamin B12-containing supplement use and parity. Further research as to whether and when milk bank donors are recommended to consume a supplement and the benefits and risks of routine vitamin B12 supplementation of DM-fed infants is warranted.</div></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"44 ","pages":"Pages 19-24"},"PeriodicalIF":6.6,"publicationDate":"2024-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Filipe Jesus , Olivia Di Vincenzo , Rúben Francisco , Catarina L. Nunes , Emi Kondo , Paulo Rocha , Cláudia S. Minderico , Luís B. Sardinha , Dale A. Schoeller , Analiza M. Silva
{"title":"Water intake in athletes: Agreement between food records and isotope-dilution methods","authors":"Filipe Jesus , Olivia Di Vincenzo , Rúben Francisco , Catarina L. Nunes , Emi Kondo , Paulo Rocha , Cláudia S. Minderico , Luís B. Sardinha , Dale A. Schoeller , Analiza M. Silva","doi":"10.1016/j.clnu.2024.11.026","DOIUrl":"10.1016/j.clnu.2024.11.026","url":null,"abstract":"<div><h3>Background</h3><div>Although water intake (WI) is commonly estimated through self-reporting, its inaccuracy is reported. Water turnover (rH<sub>2</sub>O)-derived WI is the reference method; however, it is costly. The study aimed to validate alternative methods for determining WI in a group of athletes.</div></div><div><h3>Methods</h3><div>Eighty-two athletes (20.4 ± 5.1 years; 28 females) were included in this cross-sectional validation study. Doubly labelled water (DLW) determined rH<sub>2</sub>O and rH<sub>2</sub>O-derived WI by subtracting metabolic, transcutaneous, and inspired water from rH<sub>2</sub>O (reference). The rH<sub>2</sub>O components were determined by alternative approaches: i) average values of macronutrients instead of individual food records (DLW-derived WI); ii) estimating total energy expenditure (TEE) and rCO<sub>2</sub> through a predictive equation instead of DLW (<sup>2</sup>H-derived WI); iii) estimating rH<sub>2</sub>O by prediction equation (equation-derived WI). Food records were employed to determine WI (food record-derived WI).</div></div><div><h3>Results</h3><div>Only DLW-derived WI showed no significant differences compared to reference in both sexes (females: 2 mL/day, p = 0.183; males: −4 mL/day, p = 0.118). <sup>2</sup>H-derived WI showed significant but small differences (females: 23 mL/day, p = 0.001; males: 32 mL/day, p < 0.001) while food record-derived WI showed the largest differences (females: −924 mL/day, p < 0.001; males: −1504 mL/day, p < 0.001). DLW-derived and <sup>2</sup>H-derived WI showed good performance [r<sup>2</sup> > 0.987 and concordance correlation coefficient (CCC) > 0.993], while food record-derived WI showed poor performance [r<sup>2</sup> < 0.031 and CCC < 0.133)].</div></div><div><h3>Conclusion</h3><div>Although some alternative approaches provide adequate estimates, DLW- and <sup>2</sup>H-derived WI are the only valid methods to determine WI in our sample of competitive athletes. These approaches are less costly and could contribute to the development of WI guidelines for athletes. Food records underestimate WI, but evidence-based recommendations could reduce misrecordings.</div></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 12","pages":"Pages 370-378"},"PeriodicalIF":6.6,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evertine Wesselink, Hendriek C. Boshuizen, Anne-Sophie van Lanen, Dieuwertje E. Kok, Jeroen W.G. Derksen, Karel C. Smit, Johannes H.W. de Wilt, Miriam Koopman, Anne M. May, Ellen Kampman, Fränzel J.B. van Duijnhoven
{"title":"Reply - Letter to the editor entitled “Letter to editor - Dietary and lifestyle inflammation scores in relation to colorectal cancer recurrence and all-cause mortality: A longitudinal analysis”","authors":"Evertine Wesselink, Hendriek C. Boshuizen, Anne-Sophie van Lanen, Dieuwertje E. Kok, Jeroen W.G. Derksen, Karel C. Smit, Johannes H.W. de Wilt, Miriam Koopman, Anne M. May, Ellen Kampman, Fränzel J.B. van Duijnhoven","doi":"10.1016/j.clnu.2024.11.018","DOIUrl":"10.1016/j.clnu.2024.11.018","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 12","pages":"Page 341"},"PeriodicalIF":6.6,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142681201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Riccardo Calvani , Ottavia Giampaoli , Federico Marini , Federica Del Chierico , Michele De Rosa , Giorgia Conta , Fabio Sciubba , Matteo Tosato , Anna Picca , Francesca Ciciarello , Vincenzo Galluzzo , Jacopo Gervasoni , Clara Di Mario , Luca Santoro , Barbara Tolusso , Mariangela Spagnoli , Alberta Tomassini , Walter Aureli , Francesca Toto , Stefania Pane , Francesco Landi
{"title":"Beetroot juice intake positively influenced gut microbiota and inflammation but failed to improve functional outcomes in adults with long COVID: A pilot randomized controlled trial","authors":"Riccardo Calvani , Ottavia Giampaoli , Federico Marini , Federica Del Chierico , Michele De Rosa , Giorgia Conta , Fabio Sciubba , Matteo Tosato , Anna Picca , Francesca Ciciarello , Vincenzo Galluzzo , Jacopo Gervasoni , Clara Di Mario , Luca Santoro , Barbara Tolusso , Mariangela Spagnoli , Alberta Tomassini , Walter Aureli , Francesca Toto , Stefania Pane , Francesco Landi","doi":"10.1016/j.clnu.2024.11.023","DOIUrl":"10.1016/j.clnu.2024.11.023","url":null,"abstract":"<div><h3>Background & aims</h3><div>Long-term effects of coronavirus disease 2019 (long COVID) develop in a substantial number of people following an acute COVID-19 episode. Red beetroot juice may have positive effects on multiple pathways involved in long COVID. The aim of this pilot study was to explore the impact of beetroot juice supplementation on physical function, gut microbiota, and systemic inflammation in adults with long COVID.</div></div><div><h3>Methods</h3><div>A single-center, double-blind, placebo-controlled randomized trial was conducted to test the effects of 14 days of beetroot juice supplementation, rich in nitrates and betalains, on functional and biological outcomes in adults aged between 20 and 60 years with long COVID. Participants were randomized 1:1 to receive either daily oral supplementation with 200 mL beetroot juice (∼600 mg nitrate) or placebo (∼60 mg nitrate) for 14 days. The primary endpoint was the change from baseline to day 14 in a fatigue resistance test. Secondary outcomes included the distance walked on the 6-min walk test, handgrip strength, and flow-mediated dilation. Secondary endpoints also included changes from baseline in circulating inflammatory mediators and metagenomic and fecal water metabolomic profiles. Partial least squares discriminant analysis (PLS−DA) models were built to evaluate the differences in biological variables associated with the interventions.</div></div><div><h3>Results</h3><div>Thirty-one participants were randomized in the study. Twenty-five of them (median (interquartile range) age 40 (10), 14 [56 %] women), received either beetroot juice (15) or placebo (10) and completed the study. At 14 days, fatigue resistance significantly improved from baseline (mean difference [standard error]: +21.8 [3.7] s; <em>p</em> < 0.001) with no significant differences between intervention groups. A significant increase from baseline in the distance walked on the 6-min walk test was observed (mean difference [standard error]: +30.0 [9.4] m; <em>p</em> = 0.03), which was not different between groups. Flow-mediated dilation did not differ between participants who received beetroot juice and those on placebo. PLS–DA models allowed correct classification of participants with 92.2 ± 4.4 % accuracy. Those who ingested red beetroot juice had a greater abundance of bacteria with well-known beneficial effects, including <em>Akkermansia</em>, <em>Oscillospira</em>, <em>Prevotella</em>, <em>Roseburia</em>, <em>Ruminococcaceae</em>, and <em>Turicibacter</em>, compared with placebo. Participants allocated to beetroot juice supplementation were also characterized by significantly higher levels of fecal nicotinate, trimethylamine, and markers of beetroot juice intake (e.g., 5,6-dihydroxyindole). Finally, higher levels of interferon gamma and macrophage inflammatory protein-1β were found in participants who consumed beetroot juice.</div></div><div><h3>Conclusion</h3><div>Beetroot juice supplementation for","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 12","pages":"Pages 344-358"},"PeriodicalIF":6.6,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dorothee Volkert, Anne Marie Beck, Gerd Faxén-Irving, Thomas Frühwald, Lee Hooper, Heather Keller, Judi Porter, Elisabet Rothenberg, Merja Suominen, Rainer Wirth, Michael Chourdakis
{"title":"Reply to the letter to the Editor “ESPEN guideline on nutrition and hydration in dementia - Update 2024” from Barbosa Gomes et al.","authors":"Dorothee Volkert, Anne Marie Beck, Gerd Faxén-Irving, Thomas Frühwald, Lee Hooper, Heather Keller, Judi Porter, Elisabet Rothenberg, Merja Suominen, Rainer Wirth, Michael Chourdakis","doi":"10.1016/j.clnu.2024.11.015","DOIUrl":"10.1016/j.clnu.2024.11.015","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"43 12","pages":"Pages 359-360"},"PeriodicalIF":6.6,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142686142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evertine Wesselink, Hendriek C. Boshuizen, Anne-Sophie van Lanen, Dieuwertje E. Kok, Jeroen W.G. Derksen, Karel C. Smit, Johannes H.W. de Wilt, Miriam Koopman, Anne M. May, Ellen Kampman, Fränzel J.B. van Duijnhoven
{"title":"Reply - Letter to the editor entitled “Letter to editor regarding Dietary and lifestyle inflammation scores in relation to colorectal cancer recurrence and all-cause mortality: A longitudinal analysis”","authors":"Evertine Wesselink, Hendriek C. Boshuizen, Anne-Sophie van Lanen, Dieuwertje E. Kok, Jeroen W.G. Derksen, Karel C. Smit, Johannes H.W. de Wilt, Miriam Koopman, Anne M. May, Ellen Kampman, Fränzel J.B. van Duijnhoven","doi":"10.1016/j.clnu.2024.11.014","DOIUrl":"10.1016/j.clnu.2024.11.014","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"44 ","pages":"Pages 5-6"},"PeriodicalIF":6.6,"publicationDate":"2024-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}