Feiling Ai, Marie-Theres Huemer, Beate Fischer, Violetta Ptushkina, Wolfgang Rathmann, Matthias B Schulze, Henry Völzke, Anke Hannemann, Karin Halina Greiser, Thomas Keil, Lilian Krist, Justine Tanoey, Hajo Zeeb, Stefanie Jaskulski, Nadia Obi, Katharina S Weber, Wolfgang Lieb, Sabine Schipf, Marcello Ricardo Paulista Markus, Michael Leitzmann, Michael Drey, Annette Peters, Barbara Thorand
{"title":"Corrigendum to \"Associations of the bioimpedance-derived phase angle with early and advanced stages of dysglycemia: Cross-sectional findings from a large population-based study\" [Clin Nutr 64 (2026) 106729].","authors":"Feiling Ai, Marie-Theres Huemer, Beate Fischer, Violetta Ptushkina, Wolfgang Rathmann, Matthias B Schulze, Henry Völzke, Anke Hannemann, Karin Halina Greiser, Thomas Keil, Lilian Krist, Justine Tanoey, Hajo Zeeb, Stefanie Jaskulski, Nadia Obi, Katharina S Weber, Wolfgang Lieb, Sabine Schipf, Marcello Ricardo Paulista Markus, Michael Leitzmann, Michael Drey, Annette Peters, Barbara Thorand","doi":"10.1016/j.clnu.2026.106802","DOIUrl":"https://doi.org/10.1016/j.clnu.2026.106802","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":" ","pages":"106802"},"PeriodicalIF":7.9,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149058868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response to: Bozzetti F. \"Home parenteral nutrition at the end of the life: Navigating between hopes and uncertainty\".","authors":"Darren Wong","doi":"10.1016/j.clnu.2026.106803","DOIUrl":"https://doi.org/10.1016/j.clnu.2026.106803","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":" ","pages":"106803"},"PeriodicalIF":7.9,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149073754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply - Letter to the editor - 'Vertebral landmarks as reference levels, not invariant planes: Toward standardized single-slice computed tomography body composition assessment'.","authors":"Laurent Razat, Bruno Degano, Cécile Bétry","doi":"10.1016/j.clnu.2026.106792","DOIUrl":"https://doi.org/10.1016/j.clnu.2026.106792","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":" ","pages":"106792"},"PeriodicalIF":7.9,"publicationDate":"2026-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Home parenteral nutrition at the end of the life: Navigating between hope and uncertainty.","authors":"Federico Bozzetti","doi":"10.1016/j.clnu.2026.106787","DOIUrl":"https://doi.org/10.1016/j.clnu.2026.106787","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":" ","pages":"106787"},"PeriodicalIF":7.9,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149023934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical nutritionPub Date : 2026-08-01Epub Date: 2026-06-24DOI: 10.1016/j.clnu.2026.106708
Harriët Jager-Wittenaar, Martine Sealy, Rocco Barazzoni, Renee Blaauw, Tommy Cederholm, Lee-anne Chapple, Charlene Compher, M. Isabel T.D. Correia, Ryoji Fukushima, M. Cristina Gonzalez, Gordon L. Jensen, Charles Chin Han Lew, Su Lin Lim, Ainsley Malone, Veeradej Pisprasert, Elisabet Rothenberg, Alison Steiber, Elke Naumann, Marian de van der Schueren
{"title":"Nutritional screening within the GLIM procedure—Part 1: Development of a conceptual definition of risk of malnutrition using a modified Delphi procedure","authors":"Harriët Jager-Wittenaar, Martine Sealy, Rocco Barazzoni, Renee Blaauw, Tommy Cederholm, Lee-anne Chapple, Charlene Compher, M. Isabel T.D. Correia, Ryoji Fukushima, M. Cristina Gonzalez, Gordon L. Jensen, Charles Chin Han Lew, Su Lin Lim, Ainsley Malone, Veeradej Pisprasert, Elisabet Rothenberg, Alison Steiber, Elke Naumann, Marian de van der Schueren","doi":"10.1016/j.clnu.2026.106708","DOIUrl":"10.1016/j.clnu.2026.106708","url":null,"abstract":"<div><h3>Background</h3><div>This article presents the results of the modified Delphi study conducted by the GLIM Risk of Malnutrition Working Group to develop a consensus-based conceptual definition of “risk of malnutrition,” as first step in revising the GLIM screening procedure.</div></div><div><h3>Methods</h3><div>Focus groups with nutritional care experts and patient/older adult representatives, and a literature exploration informed 46 statements on risk of malnutrition. Malnutrition experts (<em>n</em> = 112) evaluated these statements, using a five-point Likert scale. Statements with ≥75% agreement were accepted; those with ≥75% disagreement and/or neutrality were rejected. Remaining statements were marked “undecided” and re-evaluated in later rounds.</div></div><div><h3>Results</h3><div>In three questionnaire rounds (response rates 63%, 59%, and 54%), 26 statements were ultimately accepted to shape the conceptual definition of “risk of malnutrition”. The GLIM Working Group and patient/older adult representatives reviewed the pre-final professional and layperson versions. Risk of malnutrition was defined as: A dynamic state, with or without unintentional weight loss, in which an individual has one or more risk factors, that is, nutrition impact symptoms, and/or disease-related, physical, psychological, social, demographic, and economic risk factors, that may result in malnutrition and may negatively impact clinical outcomes. In the layperson version, sentences were simplified to aid comprehension.</div></div><div><h3>Conclusion</h3><div>GLIM has developed the first global (professional and layperson) conceptual definition of risk of malnutrition. This definition will guide future nutritional screening recommendations and a more preventive malnutrition approach. It also implies that screening tools covering “risk of malnutrition” should no longer be validated against signs or the diagnosis of malnutrition.</div></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"63 ","pages":"Article 106708"},"PeriodicalIF":7.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148316043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical nutritionPub Date : 2026-08-01Epub Date: 2026-06-24DOI: 10.1016/j.clnu.2026.106709
Marian A.E. de van der Schueren, Elke Naumann, Rianne ter Bekke, Rocco Barazzoni, Renée Blaauw, Tommy Cederholm, Lee-anne Chapple, Charlene Compher, M. Isabel T.D. Correia, Ryoji Fukushima, M. Cristina Gonzalez, Gordon L. Jensen, Charles Chin Han Lew, Su Lin Lim, Ainsley Malone, Veeradej Pisprasert, Elisabet Rothenberg, Alison Steiber, Martine Sealy, Harriët Jager-Wittenaar
{"title":"Nutritional screening within the GLIM procedure—Part 2: Operationalization of the concept risk of malnutrition using a modified Delphi procedure","authors":"Marian A.E. de van der Schueren, Elke Naumann, Rianne ter Bekke, Rocco Barazzoni, Renée Blaauw, Tommy Cederholm, Lee-anne Chapple, Charlene Compher, M. Isabel T.D. Correia, Ryoji Fukushima, M. Cristina Gonzalez, Gordon L. Jensen, Charles Chin Han Lew, Su Lin Lim, Ainsley Malone, Veeradej Pisprasert, Elisabet Rothenberg, Alison Steiber, Martine Sealy, Harriët Jager-Wittenaar","doi":"10.1016/j.clnu.2026.106709","DOIUrl":"10.1016/j.clnu.2026.106709","url":null,"abstract":"<div><h3>Background and aims</h3><div>Within the original Global Leadership Initiative on Malnutrition (GLIM) procedure (2019), the step on nutritional screening was not further elaborated. A new GLIM Risk of Malnutrition Working Group has recently developed a consensus-based conceptual definition of “risk of malnutrition”. The present study aimed to operationalize this definition.</div></div><div><h3>Methods</h3><div>This study consisted of: (1) a literature search to identify risk factors for malnutrition, and (2) a two-round online modified Delphi study. International professional experts (<em>n</em> = 113) in the field of malnutrition were invited to rate the importance of identified risk factors using a 9-point Likert scale. In questionnaire round 1, risk factors were rated “critically important” if ≥ 70% of the participants rated them 7–9, or “not important” if >30% rated them 1–3. The remaining risk factors were categorized as “undecided.” In questionnaire round 2, undecided risk factors were classified as “critically important” or “important, but not critical”, based on the same threshold.</div></div><div><h3>Results</h3><div>The literature search revealed 64 risk factors that were included in the Delphi questionnaires. In questionnaire rounds one (<em>n</em> = 57 participants) and two (<em>n</em> = 46 participants), 29 risk factors (from the overarching risk categories unintentional weight loss, nutrition impact symptoms, disease-related factors, physical factors, psychological factors, decreased food intake, food assimilation, and poor diet) were deemed “critically important,” 10 “important, but not critical,” and 19 “substantially important.”</div></div><div><h3>Conclusion</h3><div>In this study, we identified which risk factors are considered critical to operationalize “risk of malnutrition.” Screening for risk of malnutrition should take these relevant risk factors into account.</div></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"63 ","pages":"Article 106709"},"PeriodicalIF":7.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148316041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical nutritionPub Date : 2026-07-01Epub Date: 2026-05-15DOI: 10.1016/j.clnu.2026.106688
Akiyuki Yamamoto, Taku Oshima
{"title":"Reply - Letter to the Editor - \"Time-course metabolomic analyses of acute-phase energy metabolism in critically ill patients\"","authors":"Akiyuki Yamamoto, Taku Oshima","doi":"10.1016/j.clnu.2026.106688","DOIUrl":"10.1016/j.clnu.2026.106688","url":null,"abstract":"","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"62 ","pages":"Article 106688"},"PeriodicalIF":7.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148004858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Clinical nutritionPub Date : 2026-07-01Epub Date: 2026-05-28DOI: 10.1016/j.clnu.2026.106643
Heather Keller, Renée Blaauw, Christine Marie Mills, Gert Bischoff, Charlene Compher, Marian de van der Schueren, Krista Haines, Nicole Kiss, Charles Lew, Ainsley Malone, Claudia Maza Moscoso, Nancy Stoner, Rocco Barazzoni, Jack J. Bell, Madeleine Coetzee, M. Isabel T.D. Correia, Ryoji Fukushima, Elena George, M. Cristina Gonzalez, Leah Gramlich, TommyCederholm
{"title":"Guidance for the assessment of the dietary intake and gastrointestinal or nutrition impact symptoms etiologic criterion of GLIM: A modified-Delphi study","authors":"Heather Keller, Renée Blaauw, Christine Marie Mills, Gert Bischoff, Charlene Compher, Marian de van der Schueren, Krista Haines, Nicole Kiss, Charles Lew, Ainsley Malone, Claudia Maza Moscoso, Nancy Stoner, Rocco Barazzoni, Jack J. Bell, Madeleine Coetzee, M. Isabel T.D. Correia, Ryoji Fukushima, Elena George, M. Cristina Gonzalez, Leah Gramlich, TommyCederholm","doi":"10.1016/j.clnu.2026.106643","DOIUrl":"10.1016/j.clnu.2026.106643","url":null,"abstract":"<div><div>The GLIM malnutrition diagnostic framework includes the etiologic criterion for reduced dietary intake or assimilation (i.e., digestion or absorption). This criterion required further specification to support consistent use in clinical practice. Three rounds of a modified Delphi was undertaken to develop consensus on guidance to support identification of this criterion. A working group (<em>n</em> = 11) developed surveys iteratively. Invited global experts with diverse disciplines and practice contexts (<em>n</em> = 30) fully completed surveys; consensus was determined at 75% agreement. Three surveys and rounds of voting resulted in 15 guidance statements. Notable points include: (a) using usual intake as the comparator for reduced dietary intake rather than energy requirement, (b) use of gastrointestinal symptoms and nutrition impact symptoms to determine challenges with absorption or assimilation, rather than solely gastrointestinal conditions, and (c) using clinical judgment to determine severity of these symptoms. The final criterion is “less than or equal to 50% dietary intake in the last week or any reduction in intake greater than 2 weeks OR severe gastrointestinal or nutrition impact symptoms (e.g., dysphagia, nausea, vomiting, diarrhea) as a result of an acute or chronic condition or therapy.” Future work should confirm the feasibility of this criterion in clinical practice and its criterion validity within the GLIM framework.</div></div>","PeriodicalId":10517,"journal":{"name":"Clinical nutrition","volume":"62 ","pages":"Article 106643"},"PeriodicalIF":7.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148053135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}