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Foreword: Clinically Focused Insights on the Placenta and Umbilical Cord: An Evidence-based Symposium. 临床聚焦的见解在胎盘和脐带：循证研讨会。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2025-03-01 Epub Date: 2024-12-09 DOI: 10.1097/GRF.0000000000000920
Justin S Brandt, Yinka Oyelese
{"title":"Foreword: Clinically Focused Insights on the Placenta and Umbilical Cord: An Evidence-based Symposium.","authors":"Justin S Brandt, Yinka Oyelese","doi":"10.1097/GRF.0000000000000920","DOIUrl":"10.1097/GRF.0000000000000920","url":null,"abstract":"<p><p>In this symposium, we introduce a collection of reviews that delve into the diverse clinically relevant aspects of the placenta and umbilical cord. The symposium addresses placenta previa and abruption; pathology, genetics, and imaging of the placenta; infections of the placenta; and ischemic placental disease. The umbilical cord's essential function as a fetal lifeline is explored, with an emphasis on the clinical repercussions of its dysfunction, including vasa previa and other umbilical cord abnormalities. This curated collection of reviews, which synthesizes the placenta's and umbilical cord's fundamental role in maternal-fetal health, underscores the clinical importance of these structures in pregnancy.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":" ","pages":"68-71"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ischemic Placental Disease: Epidemiology and Impact on Maternal and Offspring Health Along the Life Course. 缺血性胎盘疾病：流行病学及其对母婴健康的影响。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2025-03-01 Epub Date: 2024-12-06 DOI: 10.1097/GRF.0000000000000914
Emily E Daggett, Cande V Ananth
{"title":"Ischemic Placental Disease: Epidemiology and Impact on Maternal and Offspring Health Along the Life Course.","authors":"Emily E Daggett, Cande V Ananth","doi":"10.1097/GRF.0000000000000914","DOIUrl":"10.1097/GRF.0000000000000914","url":null,"abstract":"<p><p>Ischemic placental disease (IPD) is a constellation of obstetrical complications that include preeclampsia, placental abruption, and fetal growth restriction and affects 12% to 15% of pregnancies. The unifying pathophysiological mechanism that precedes all 3 complications is uteroplacental ischemia as a consequence of inadequate (or failure of) physiological transformation of the maternal uterine spiral arteries, endothelial cell dysfunction, and increased oxidative stress. This review summarizes the IPD literature, focusing on the epidemiology and risk factors, the effects of IPD on short and long-term maternal complications, and the association of IPD with perinatal, childhood, and long-term complications in offspring.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":" ","pages":"105-110"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human Papillomavirus Infections and Sequela in Women.
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2025-02-27 DOI: 10.1097/GRF.0000000000000930
Mary J Stokes, Paulina R Ramirez, Nicole M Spencer, Erin L Nelson
{"title":"Human Papillomavirus Infections and Sequela in Women.","authors":"Mary J Stokes, Paulina R Ramirez, Nicole M Spencer, Erin L Nelson","doi":"10.1097/GRF.0000000000000930","DOIUrl":"https://doi.org/10.1097/GRF.0000000000000930","url":null,"abstract":"<p><p>Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States, with up to 90% of females infected at some point in their lifetime. While most HPV infections will be cleared by the immune system within 2 years, persistent HPV infection may result in anogenital warts, dysplasia of the cervix, vagina, vulva, and squamous cell carcinoma. This chapter will review the epidemiology, microbiology, progression, and treatment of HPV-related genital disease in women.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143514856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genital Herpes Simplex Virus Infections in Women-A Clinical Update.
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2025-02-26 DOI: 10.1097/GRF.0000000000000933
Nir Meller
{"title":"Genital Herpes Simplex Virus Infections in Women-A Clinical Update.","authors":"Nir Meller","doi":"10.1097/GRF.0000000000000933","DOIUrl":"https://doi.org/10.1097/GRF.0000000000000933","url":null,"abstract":"<p><p>Genital herpes is a relatively common chronic lower genital tract sexually transmitted infection caused by herpes simplex virus types 1 and 2 (HSV-1 and HSV-2). It is characterized by recurrent, self-limited genital ulcers, and it is the leading cause of genital ulcer disease worldwide (1). The impact of genital herpes on sexual and reproductive health, including the risk of perinatal infection, necessitates a profound understanding of its clinical presentation, diagnosis, treatment, and prevention. This chapter aims to review the critical clinical aspects of HSV in women, emphasizing relevant evidence-based data.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gonorrhea and Chlamydia Infections in Women.
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2025-02-26 DOI: 10.1097/GRF.0000000000000931
Adrienne Pyle, Lindsay Garner, Cristina Wallace Huff
{"title":"Gonorrhea and Chlamydia Infections in Women.","authors":"Adrienne Pyle, Lindsay Garner, Cristina Wallace Huff","doi":"10.1097/GRF.0000000000000931","DOIUrl":"https://doi.org/10.1097/GRF.0000000000000931","url":null,"abstract":"<p><p>This chapter provides an in-depth overview of gonorrhea and chlamydia, 2 common sexually transmitted infections (STIs) caused by the bacteria Neisseria gonorrhoeae and Chlamydia trachomatis, respectively. It covers their epidemiology, transmission, and risk factors, highlighting the global burden of these infections. It also describes the clinical manifestations of each disease, which range from asymptomatic to pelvic inflammatory disease and infertility. Diagnostic techniques are discussed alongside recommended treatment regimens and antibiotic resistance concerns. In addition, it explores prevention strategies and the importance of sexual health education and screening programs.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexually Transmitted Infection Considerations Following Sexual Assault.
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2025-02-18 DOI: 10.1097/GRF.0000000000000928
Karley Dutra, Ariana Lewis, Rachel Counts
{"title":"Sexually Transmitted Infection Considerations Following Sexual Assault.","authors":"Karley Dutra, Ariana Lewis, Rachel Counts","doi":"10.1097/GRF.0000000000000928","DOIUrl":"https://doi.org/10.1097/GRF.0000000000000928","url":null,"abstract":"<p><p>Sexual assault is common, disproportionately impacting women, persons of color, and young adults. Evaluation should include a history and exam, collection of forensic evidence, and evaluation for mental health disorders. Management of sexually transmitted infections (STI) is important, as 15% will acquire an STI. Prophylaxis is recommended for gonorrhea, chlamydia, and, for individuals with vaginas, trichomonas. HIV and hepatitis B post-exposure prophylaxis are indicated in high-risk scenarios. HPV vaccination is recommended. Follow-up and lab monitoring is indicated for up to 6 months. We aim to summarize up-to-date evidence on the screening, evaluation, and management of STIs following sexual assault.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143440074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Role of Interventional Radiology in Managing Placenta Accreta Spectrum Disorder. 介入放射学在治疗胎盘增生谱系障碍中的作用。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2025-01-22 DOI: 10.1097/GRF.0000000000000925
Uma Deshmukh, Waleska Pabon-Ramos, Raj Ayyagari
{"title":"The Role of Interventional Radiology in Managing Placenta Accreta Spectrum Disorder.","authors":"Uma Deshmukh, Waleska Pabon-Ramos, Raj Ayyagari","doi":"10.1097/GRF.0000000000000925","DOIUrl":"https://doi.org/10.1097/GRF.0000000000000925","url":null,"abstract":"<p><p>Interventional Radiology (IR) can be a crucial player in managing placenta accrete spectrum disorder (PAS), offering minimally invasive angiographic techniques that can prevent or control hemorrhage and preserve fertility. These include prophylactic balloon occlusion of the aorta or iliac arteries, preoperative catheter placement in the iliac or uterine arteries for subsequent embolization, or pre-emptive arterial embolization preceding hysterotomy and delivery. This review provides obstetricians with an overview of IR's role in the management of PAS by describing specific endovascular techniques; existing outcomes data; and considerations for protocol development, preoperative planning, and intraoperative dynamics for when IR assists with PAS cases.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143001297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anesthetic Considerations and Blood Utilization for Placenta Accreta Spectrum. 胎盘增生谱的麻醉注意事项和血液利用。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-12-11 DOI: 10.1097/GRF.0000000000000921
Philip E Hess, Yunping Li
{"title":"Anesthetic Considerations and Blood Utilization for Placenta Accreta Spectrum.","authors":"Philip E Hess, Yunping Li","doi":"10.1097/GRF.0000000000000921","DOIUrl":"https://doi.org/10.1097/GRF.0000000000000921","url":null,"abstract":"<p><p>The anesthetic management of the patient with placenta accreta spectrum begins before surgery by assessing the patient and their comorbidities and providing psychological preparation for the perioperative period. Choosing neuraxial or general anesthesia for surgery balances the procedure's clinical needs with the patient's desires. Intraoperatively, management of homeostasis during acute blood loss requires assessments of central volume to avoid over-transfusion. Viscoelastic testing may be useful to assess coagulation to target the replacement of coagulation factors. Postoperative care is an essential continuum of the procedure, and the availability of bedside ultrasound can aid rapid decision-making.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":" ","pages":""},"PeriodicalIF":1.4,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142806316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differential Receipt of Genetic Services Among Patients With Gynecologic Cancer and Their Relatives: A Review of Challenges to Health Equity. 妇科癌症患者及其亲属接受遗传服务的差异：健康公平挑战综述》。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-12-01 Epub Date: 2024-09-27 DOI: 10.1097/GRF.0000000000000893
Alexa Kanbergs, J Alejandro Rauh-Hain, Roni N Wilke
{"title":"Differential Receipt of Genetic Services Among Patients With Gynecologic Cancer and Their Relatives: A Review of Challenges to Health Equity.","authors":"Alexa Kanbergs, J Alejandro Rauh-Hain, Roni N Wilke","doi":"10.1097/GRF.0000000000000893","DOIUrl":"10.1097/GRF.0000000000000893","url":null,"abstract":"<p><p>Up to 14% of endometrial cancers and 23% of epithelial ovarian cancers are associated with genetic predispositions. Referral for genetic testing and counseling can significantly impact a patient's oncologic outcomes. However, significant disparities in genetic referral and testing exist within medically underserved and minority populations in the United States. These disparities in care and access to care are multifactorial, often involving patient-level, health care-level, and system-level factors. In this review, we focus on disparities in genetic testing among patients with ovarian and uterine cancer, and the missed opportunities for primary cancer prevention among their relatives.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":" ","pages":"666-671"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Germline Variants of Uncertain Significance in Gynecologic Oncology Patients. 妇科肿瘤患者中意义不明的基因变异。
IF 1.4 4区 医学
Clinical obstetrics and gynecology Pub Date : 2024-12-01 Epub Date: 2024-09-26 DOI: 10.1097/GRF.0000000000000898
Julia Cooper, Leigha Senter
{"title":"Germline Variants of Uncertain Significance in Gynecologic Oncology Patients.","authors":"Julia Cooper, Leigha Senter","doi":"10.1097/GRF.0000000000000898","DOIUrl":"10.1097/GRF.0000000000000898","url":null,"abstract":"<p><p>Germline and somatic genetic/genomic testing are commonly ordered for gynecologic oncology patients. Genetic tests can inform disease etiology, prognosis, treatment decisions, and risk to the patient's relatives. Variants of uncertain significance (VUSs) are frequently encountered and have a more nuanced interpretation than straightforward pathogenic or benign variant classifications. Clinical care providers should be familiar with why and how VUSs are reported, their clinical significance, variant reclassification practices, and patient perceptions of VUSs.</p>","PeriodicalId":10415,"journal":{"name":"Clinical obstetrics and gynecology","volume":" ","pages":"672-675"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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