胎儿贫血：当前临床方法的叙述回顾。

IF 1.4 4区医学 Q3 OBSTETRICS & GYNECOLOGY

Clinical obstetrics and gynecology Pub Date : 2025-09-01 Epub Date: 2025-07-01 DOI:10.1097/GRF.0000000000000949

Enaja V Sambatur, May Abiad, Faezeh Aghajani, Alireza A Shamshirsaz

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引用次数: 0

摘要

胎儿贫血包括多种病因，最明显的是红细胞异体免疫，如果不加以认识，会对胎儿和新生儿的健康构成严重风险。本文概述了病理生理学、筛查策略和不断发展的诊断工具，如无创基因分型和MCA多普勒。我们研究了免疫调节疗法，如IVIg和nipocalimab，并讨论了宫内输血的技术考虑。最后，我们讨论了新生儿管理和长期结果。随着产前诊断和有针对性的干预措施的增加，及时识别和治疗胎儿贫血可以显着提高围产期存活率并减少并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Fetal Anemia: A Narrative Review of Current Clinical Approaches.

Fetal anemia encompasses a wide range of etiologies, most notably red cell alloimmunization, and poses serious risks to fetal and neonatal health if unrecognized. This narrative review outlines the pathophysiology, screening strategies, and evolving diagnostic tools such as noninvasive genotyping and MCA Doppler. We examine immunomodulatory therapies like IVIg and nipocalimab, and discuss technical considerations for intrauterine transfusions. Finally, we address neonatal management and long-term outcomes. With increasing access to prenatal diagnostics and targeted interventions, timely recognition and treatment of fetal anemia can significantly improve perinatal survival and reduce complications.

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来源期刊

Clinical obstetrics and gynecology 医学-妇产科学

CiteScore

2.70

自引率

0.00%

发文量

186

审稿时长

3 months

期刊介绍： Each issue of Clinical Obstetrics and Gynecology is a complete symposium on one or two timely topics of interest in obstetrics and gynecology. For each quarterly issue, two prominent guest editors solicit contributions on key clinical topics of interest to practicing physicians. Procedures, current clinical problems, medical and surgical treatments, and effective diagnostic aids are all carefully reviewed in original articles. The result is an instructive resource that dispenses trustworthy clinical guidance that enhances your understanding of key areas of your practice.