{"title":"On the contribution of the ventromedial prefrontal cortex to the neural representation of past memories","authors":"Valerio Santangelo","doi":"10.1080/17588928.2022.2076072","DOIUrl":"https://doi.org/10.1080/17588928.2022.2076072","url":null,"abstract":"ABSTRACT Tallman and colleagues (this issue) showed that memory consolidation of laboratory materials produces, even at short intervals, changes in cortical activity within a widespread network of brain regions. These changes, however, do not encompass a core memory region, namely the ventromedial prefrontal cortex (vmPFC). Here, I discuss research showing that the neural activity of the vmPFC is sensitive to the remoteness of memories, especially using tasks that involve autobiographical recollection. Taken together, these findings appear to highlight a differential contribution of the vmPFC according to the nature of the to-be-remembered material (laboratory vs. autobiographical) that might be further investigated by future research.","PeriodicalId":10413,"journal":{"name":"Cognitive Neuroscience","volume":"13 1","pages":"154 - 155"},"PeriodicalIF":2.0,"publicationDate":"2022-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43776479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"These things take time: what is the role of the hippocampus in recognition memory over extended delays?","authors":"C. Kirwan","doi":"10.1080/17588928.2022.2076073","DOIUrl":"https://doi.org/10.1080/17588928.2022.2076073","url":null,"abstract":"ABSTRACT In a clever experimental design, Tallman, Clark, and Smith (this issue) tested the changes in fMRI activation and functional connectivity in the hippocampus and cortex as a function of memory age. They found that activation changed according to a power function (both increasing and decreasing) in several cortical regions but not within the hippocampus or medial temporal lobe (MTL). Further, functional connectivity increased with memory age between cortical regions but decreased for the hippocampus. Taken together, these results offer strong support for the standard consolidation model. However, they leave open the question of what role the hippocampus plays in recognition memory performance.","PeriodicalId":10413,"journal":{"name":"Cognitive Neuroscience","volume":"13 1","pages":"147 - 148"},"PeriodicalIF":2.0,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47538053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Challenges facing fMRI studies of systems consolidation","authors":"J. Manns","doi":"10.1080/17588928.2022.2076074","DOIUrl":"https://doi.org/10.1080/17588928.2022.2076074","url":null,"abstract":"ABSTRACT Tallman and colleagues (this issue) report fMRI findings in support of the classic view of memory consolidation over its main challenger, the multiple trace theory. The present commentary highlights some of the obstacles facing any fMRI study of memory consolidation and notes which challenges were tackled by Tallman and colleagues and which challenges might be insurmountable.","PeriodicalId":10413,"journal":{"name":"Cognitive Neuroscience","volume":"13 1","pages":"149 - 150"},"PeriodicalIF":2.0,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44268630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive NeurosciencePub Date : 2022-01-01Epub Date: 2020-12-24DOI: 10.1080/17588928.2020.1828323
George Zacharopoulos, Uri Hertz, Ryota Kanai, Bahador Bahrami
{"title":"The effect of feedback valence and source on perception and metacognition: An fMRI investigation.","authors":"George Zacharopoulos, Uri Hertz, Ryota Kanai, Bahador Bahrami","doi":"10.1080/17588928.2020.1828323","DOIUrl":"https://doi.org/10.1080/17588928.2020.1828323","url":null,"abstract":"<p><p>Receiving feedback from our environment that informs us about the outcomes of our actions helps us assess our abilities (e.g., metacognition) and to flexibly adapt our behavior, consequently increasing our chances of success. However, a detailed examination of the effect of feedback on the brain activation during perceptual and confidence judgments as well as the interrelations between perceptual accuracy, prospective and retrospective confidence remains unclear. Here we used functional magnetic resonance imaging (fMRI) to examine the neural response to feedback valence and source in visual contrast discrimination together with prospective confidence judgments at the beginning of each block and retrospective confidence judgments after every decision. Positive feedback was associated with higher activation (or lower deactivation depending on the area) in areas previously involved in attention, performance monitoring and visual regions during the perceptual judgment than during the confidence judgment. Changes in prospective confidence were positively related to changes in perceptual accuracy as well as to the corresponding retrospective confidence. Thus, feedback information impacted multiple, qualitatively different brain processing states, and we also revealed the dynamic interplay between prospective, perceptual accuracy and retrospective self-assessment.</p>","PeriodicalId":10413,"journal":{"name":"Cognitive Neuroscience","volume":" ","pages":"38-46"},"PeriodicalIF":2.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17588928.2020.1828323","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38746356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Left-prefrontal alpha-dynamics predict executive working-memory functioning in elderly people.","authors":"Oded Meiron, Elishai Ezra Tsur, Hagai Factor, Shoham Jacobsen, David Yoel Salomon, Nir Kraizler, Efraim Jaul","doi":"10.1080/17588928.2021.1911977","DOIUrl":"https://doi.org/10.1080/17588928.2021.1911977","url":null,"abstract":"<p><p>Recent findings suggest that electroencephalography (EEG) oscillations in the theta and alpha frequency-bands reflect synchronized interregional neuronal activity and are considered to reflect cognitive-control, and executive working memory mechanisms in humans. Above the age of 50 years, hypothesized pronounced alterations in alpha and theta-band power at resting or across different WM-functioning brain states may well be due to pre-dementia cognitive impairments, or increasing severity of age-related neurological disorders. Executive working memory (EWM) functioning was assessed in older-adult participants (54 to 83 years old) by obtaining their WM-related EEG oscillations and WM performance scores. WM performance and WM brain-state EEG were recorded during online-WM periods as well as during specific online WM events within EWM periods, and during resting <i>offline-WM</i> periods that preceded online-WM periods. Left-prefrontal alpha-power was enhanced during offline-WM periods versus online-WM periods and was significantly related to WM accuracy. Left-prefrontal alpha power and left prefrontal-parietal theta power anterior-posterior difference-gradient during online WM activity were related to reaction times (RT's). Importantly, during active-storage events, WM-offset offline-periods, and preparatory pre-retrieval events, excessive left-prefrontal alpha activity was related to poor EWM performance. The potential for developing targeted noninvasive cognition-enhancing interventions and developing clinical-monitoring EEG-based biomarkers of pathological cognitive-decline in elderly people is discussed.</p>","PeriodicalId":10413,"journal":{"name":"Cognitive Neuroscience","volume":" ","pages":"15-25"},"PeriodicalIF":2.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17588928.2021.1911977","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38898474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aleea L Devitt, Preston P Thakral, Daniel L Schacter
{"title":"Decoding the emotional valence of future thoughts.","authors":"Aleea L Devitt, Preston P Thakral, Daniel L Schacter","doi":"10.1080/17588928.2021.1906638","DOIUrl":"https://doi.org/10.1080/17588928.2021.1906638","url":null,"abstract":"<p><p>Affective future thinking allows us to prepare for future outcomes, but we know little about neural representation of emotional future simulations. We used a multi-voxel pattern analysis to determine whether patterns of neural activity can reliably distinguish between positive and negative future simulations. Neural patterning in the anterior cingulate and ventromedial prefrontal cortices distinguished positive from negative future simulations, indicating that these regions code for the emotional valence of future events. These results support prior findings that anterior medial regions contain representations of emotions across various stimuli, and contribute to identifying potential rewarding outcomes of future events. More broadly, these results demonstrate that the phenomenological features of future thinking can be decoded using neural activity.</p>","PeriodicalId":10413,"journal":{"name":"Cognitive Neuroscience","volume":"13 1","pages":"10-14"},"PeriodicalIF":2.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17588928.2021.1906638","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10454814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive NeurosciencePub Date : 2022-01-01Epub Date: 2021-07-20DOI: 10.1080/17588928.2021.1953973
Juan J Imbernón, Carmen Aguirre, Carlos J Gómez-Ariza
{"title":"Selective directed forgetting is mediated by the lateral prefrontal cortex: Preliminary evidence with transcranial direct current stimulation.","authors":"Juan J Imbernón, Carmen Aguirre, Carlos J Gómez-Ariza","doi":"10.1080/17588928.2021.1953973","DOIUrl":"https://doi.org/10.1080/17588928.2021.1953973","url":null,"abstract":"<p><p>Recent research has shown that providing a cue to selectively forget one subset of previously learned facts may result in specific forgetting of this information. Behavioral evidence suggests that this selective directed forgetting effect relies on executive control and is a direct consequence of active, rather than passive, mechanisms. To date, however, no previous research has addressed the neural underpinnings of selective directed forgetting. Since the lateral prefrontal cortex is thought to mediate motivated forgetting by exerting top-down control over the brain structures that underpin memory representations, the present study aimed to test the hypothesis that selective directed forgetting is prefrontally driven. Specifically, we used transcranial direct current stimulation to disrupt activity in the dorsolateral prefrontal cortex, using a stimulation protocol that has already been shown to be effective in this regard. Our results reveal that, in contrast to sham stimulation, real stimulation abolished selective directed forgetting. Additionally, real stimulation hindered performance in an updating working memory task thought to recruit the lateral prefrontal cortex. These findings, complementing others obtained with a variety of memory control tasks, support the hypothesis that memory downregulation is achieved by control processes mediated by the right lateral prefrontal cortex.</p>","PeriodicalId":10413,"journal":{"name":"Cognitive Neuroscience","volume":"13 2","pages":"77-86"},"PeriodicalIF":2.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17588928.2021.1953973","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39201520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Does adding <i>beer</i> to <i>coffee</i> enhance the activation of <i>drinks</i>? An ERP study of semantic category priming.","authors":"Marcela Ovando-Tellez, Benjamin Rohaut, Nathalie George, Theophile Bieth, Laurent Hugueville, Yoan Ibrahim, Ophelie Courbet, Lionel Naccache, Richard Levy, Béatrice Garcin, Emmanuelle Volle","doi":"10.1080/17588928.2021.1940117","DOIUrl":"https://doi.org/10.1080/17588928.2021.1940117","url":null,"abstract":"<p><p>Categorization - whether of objects, ideas, or events - is a cognitive process that is essential for human thinking, reasoning, and making sense of everyday experiences. Categorization abilities are typically measured by the Wechsler Adult Intelligence Scale (WAIS) similarity subtest, which consists of naming the shared category of two items (e.g., 'How are beer and coffee alike'). Previous studies show that categorization, as measured by similarity tasks, requires executive control functions. However, other theories and studies indicate that semantic memory is organized into taxonomic and thematic categories that can be activated implicitly in semantic priming tasks. To explore whether categories can be primed during a similarity task, we developed a double semantic priming paradigm. We measured the priming effect of two primes on a target word that was taxonomically or thematically related to both primes (double priming) or only one of them (single priming). Our results show a larger and additive priming effect in the double priming condition compared to the single priming condition, as measured by both response times and, more consistently, event-related potentials. Our results support the view that taxonomic and thematic categorization can occur during a double priming task and contribute to improving our knowledge on the organization of semantic memory into categories. These findings show how abstract categories can be activated, which likely shapes the way we think and interact with our environment. Our study also provides a new cognitive tool that could be useful to understand the categorization difficulties of neurological patients.</p>","PeriodicalId":10413,"journal":{"name":"Cognitive Neuroscience","volume":" ","pages":"61-76"},"PeriodicalIF":2.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17588928.2021.1940117","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39160944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive NeurosciencePub Date : 2022-01-01Epub Date: 2021-08-22DOI: 10.1080/17588928.2021.1963694
Nicole A Forner-Phillips, Jessica E Brown, Briana M Silck, Robert S Ross
{"title":"Alpha oscillatory power decreases are associated with better memory for higher valued information.","authors":"Nicole A Forner-Phillips, Jessica E Brown, Briana M Silck, Robert S Ross","doi":"10.1080/17588928.2021.1963694","DOIUrl":"https://doi.org/10.1080/17588928.2021.1963694","url":null,"abstract":"<p><p>Items associated with high value are often better remembered. Value may increase attention toward item in context associations. Alpha oscillations (8-13 Hz) are thought to underlie attention and their observation may reveal the role attention plays in value-based memory. In the current study, EEG is used to record brain activity while participants (n = 30) completed a source recognition memory task where items were associated with either high or low value backgrounds to determine whether greater attentional resources are deployed when encoding high value information. Participants demonstrated better memory for objects associated with high value backgrounds. Alpha oscillatory power in occipital/temporal brain regions exhibited greater desynchronization when encoding objects associated with high value that were later successfully recalled compared to those associated with low value. In addition, beta oscillatory power in midfrontal brain regions exhibited greater desynchronization during successful recall of high value objects compared to low value objects. Together these results suggest that more attentional resources are used to encode information that is associated with high value, which increases the likelihood of later successful memory recall.</p>","PeriodicalId":10413,"journal":{"name":"Cognitive Neuroscience","volume":"13 2","pages":"87-98"},"PeriodicalIF":2.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39336087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cognitive NeurosciencePub Date : 2022-01-01Epub Date: 2021-03-19DOI: 10.1080/17588928.2021.1877648
Rongjuan Zhu, Yangmei Luo, Ziyu Wang, Xuqun You
{"title":"Within-session repeated transcranial direct current stimulation of the posterior parietal cortex enhances spatial working memory.","authors":"Rongjuan Zhu, Yangmei Luo, Ziyu Wang, Xuqun You","doi":"10.1080/17588928.2021.1877648","DOIUrl":"https://doi.org/10.1080/17588928.2021.1877648","url":null,"abstract":"<p><p>Spatial working memory (SWM) is an essential cognitive ability that supports complex tasks, but its capacity is limited. Studies using transcranial direct current stimulation (tDCS) have shown potential benefits for SWM performance. Recent studies have shown that repeated short applications of tDCS affected corticospinal excitability. Moreover, neuroimaging studies have indicated that the pattern of neural activity measured in the posterior parietal cortex (PPC) tracks SWM ability. It is unknown whether repeated tDCS can enhance SWM and whether varied tDCS protocols (single 10 min tDCS, 10 min tDCS-5 min break-10 min tDCS, 10 min tDCS-20 min break-10 min tDCS) over the right PPC have different effects on SWM. The current study investigated whether offline single-session and repeated tDCS over the right PPC affects SWM updating, as measured by spatial 2-back and 3-back tasks. The results showed that stimulating the right PPC with repeated 10 min anodal tDCS significantly improved the response speed of the spatial 2-back task relative to single-session tDCS. Repeated 10 min tDCS with a longer interval (i.e. inter-stimulation interval of 20 min) enhanced the response speed of the spatial 3-back task. Altogether these findings provide causal evidence that suggests that the right PPC plays an important role in SWM. Furthermore, repeated tDCS with longer intervals may be a promising intervention for improving SWM-related function.</p>","PeriodicalId":10413,"journal":{"name":"Cognitive Neuroscience","volume":" ","pages":"26-37"},"PeriodicalIF":2.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/17588928.2021.1877648","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25495874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}