Clinical Obesity最新文献

{"title":"Challenges in child and adolescent health across the Arab Gulf countries—Focus on metabolic health","authors":"Basma Haris,&nbsp;Madeeha Kamal,&nbsp;Sadriya Alkohji,&nbsp;Shahrad Taheri,&nbsp;Khalid Hussain","doi":"10.1111/cob.70027","DOIUrl":"10.1111/cob.70027","url":null,"abstract":"<p>The Gulf Cooperation Council (GCC) consists of six member states (Bahrain, Kuwait, Oman, Qatar Saudi Arabia and the United Arab Emirates). The combination of an increasing youth population combined with rapid modernisation, increasing per capita income and the paradigm shift towards unhealthy and affluent lifestyles has created a significant burden of non-communicable diseases (NCDs), especially obesity and diabetes. The aim of this review is to discuss the prevalence of childhood/adolescent obesity and diabetes in the GCC region, which are some of the highest in the world. The review also focuses on the major challenges the GCC region faced in dealing with these lifestyle-related NCDs. Children and adolescents lack access to specialised professionals for disease management across all healthcare services in the region, with a lack of multidisciplinary teams and support groups. The development of culturally acceptable and community-based strategies to promote healthy lifestyles at home and in schools will be essential to achieve sustainable change in these countries to reduce the health and economic burden of metabolic health diseases in children and adolescents in the region.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.70027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimating the association and timing of occurrence between obesity and related comorbidity outcomes in a real-world setting: A cohort study in the United States","authors":"Firas Dabbous,&nbsp;Jigish Bhavsar,&nbsp;Jayashri Desai,&nbsp;Anthony Fabricatore,&nbsp;Bríain Ó. Hartaigh,&nbsp;Wojciech Michalak,&nbsp;Sariya Udayachalerm,&nbsp;Cynthia Saiontz-Martinez,&nbsp;Zhenxiang Zhao,&nbsp;Fatima Cody Stanford","doi":"10.1111/cob.70026","DOIUrl":"10.1111/cob.70026","url":null,"abstract":"<p>To understand the prevalence, incidence and sequence of obesity-related comorbidities (ORCs) among people with obesity compared with those with a normal body mass index (BMI). People with obesity (BMI ≥30 kg/m²) and normal BMI (BMI 18.5 to &lt;25 kg/m²) were matched 1:1 using a large United States claims-linked electronic health record database. The index date was the date of the first qualifying BMI. Prevalence was assessed at baseline (12 months pre-index date); incidence and sequence of new ORCs were assessed during follow-up. Each cohort included 57 978 people. At least 1 ORC was present at baseline in 61.1% and 49.6% of the obesity and normal BMI cohorts, respectively. During follow-up (median 61 months) event rates per 1000 person-years of new ORCs were higher in the obesity cohort than the normal BMI cohort (572 vs. 378, respectively). In both cohorts, musculoskeletal pain was the most frequent new ORC, followed by dyslipidemia and hypertension. Median times to the first, second and third new ORC were shorter in the obesity cohort compared with the normal BMI cohort by 0.67, 0.81 and 0.66 years, respectively. People with obesity had a higher prevalence and incidence, and accelerated onset of ORCs compared with those with normal BMI.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.70026","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of weight on daily activities questionnaire in patients with overweight or obesity: Psychometric evaluation using data from the OASIS 1 trial","authors":"Lisa von Huth Smith,&nbsp;Diane Whalley,&nbsp;Stuart Yarr,&nbsp;Jonathan Comins,&nbsp;Sheri E. Fehnel","doi":"10.1111/cob.70015","DOIUrl":"10.1111/cob.70015","url":null,"abstract":"<p>The Impact of Weight on Daily Activities Questionnaire (IWDAQ) is a patient-reported outcome measure that uses a novel, adaptive design to assess the limitations in daily activities that are most important to individuals attempting to lose weight. During the first round of completing the IWDAQ, respondents are presented with 18 everyday activities that can be limited by excess weight and asked to choose the three activities they would most like to see improve with weight loss. They are then asked to rate the degree of limitation they experience with these three activities at baseline and at follow-up assessments. Using data from a weight-management clinical trial (OASIS 1, NCT05035095), we evaluated the IWDAQ's measurement properties, determined optimal scoring, and estimated thresholds of meaningful within-patient change. Our analyses demonstrated that the IWDAQ Composite Score offers a reliable and valid personalized measure of limitations in daily activities due to excess weight. The adaptive design of the IWDAQ ensures the patient-centricity of the measure, thereby complementing existing measures of functioning in the context of weight-management clinical trials. Evaluations using data from additional studies would be valuable in extending the psychometric evidence for the IWDAQ.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.70015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to “Managing the New Wave of Weight Loss Medication in General Practice: A Qualitative Study”","authors":"","doi":"10.1111/cob.70028","DOIUrl":"10.1111/cob.70028","url":null,"abstract":"<p>Andreassen P, Jensen SD, Bruun JM, et al. Managing the new wave of weight loss medication in general practice: a qualitative study. <i>Clin Obes</i>. 2024;14(3):e12666. doi:10.1111/cob.12666</p><p><i>The equal authorship designation was missing from this article at the time of publication. Pernille Andreassen and Sissel Due Jensen contributed equally to this article</i>.</p><p><i>We apologize for the error</i>.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.70028","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144148945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The tighter the stoma, the greater the loss: A narrower gastrojejunostomy is more beneficial for weight loss following roux-en-Y gastric bypass","authors":"Keivan Kalali,&nbsp;Tooraj Zandbaf,&nbsp;Ali Esparham,&nbsp;Soheil Ahmadyar,&nbsp;Ali Jangjoo,&nbsp;Mojtaba Meshkat,&nbsp;Mohammad Ebrahim Kalantari,&nbsp;Mohammad Javad Ghamari,&nbsp;Alireza Rezapanah,&nbsp;Amin Dalili","doi":"10.1111/cob.70013","DOIUrl":"10.1111/cob.70013","url":null,"abstract":"<div>\u0000 \u0000 <p>The optimal size of Gastrojejunostomy (GJ) in Laparoscopic Roux-EnY Gastric Bypass (LRYGB) for a- preferential weight loss is still unknown. This study aimed to investigate the influence of linear-stapled GJ size in long-term LRYGB weight reduction results. We performed a retrospective analysis of 100 patients who underwent LRYGB surgery between January and July 2021. The patients were divided into two 50-patient groups based on the size of their linear-stapled GJ, either 30 or 45 mm. Their weight loss was observed and compared on day 15, and the following appointments were 1, 3, 6, 9, 12, 18, and 24 months after surgery. After 24 months, the 30-mm group reduced their BMI by an average of 19.23, compared with the 16.43 kg/m² of the 45-mm group (<i>p</i> &lt; .001). Overall, repeated measures ANOVA showed a beneficial weight loss pattern for the 30-mm group in all four categories (weight, BMI, EWL, and TWL). Upon adjusting for age, biliopancreatic length, alimentary length, sex, history of diabetes, and a history of hypertension in repeated measures ANOVA, this difference remained significantly in favour of the 30-mm GJ. Based on the results of this study, performing a gastrojejunostomy with a 30-mm stapler compared to a 45-mm stapler increases weight loss in LRYGB patients.</p>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144093106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing risk factors and reoperation rates for laparoscopic sleeve gastrectomy and laparoscopic Roux-en-Y gastric bypass","authors":"Jana K. Elsawwah,&nbsp;Christina T. Nici,&nbsp;Ashish Padnani,&nbsp;Rolando H. Rolandelli,&nbsp;Zoltan H. Nemeth","doi":"10.1111/cob.70023","DOIUrl":"10.1111/cob.70023","url":null,"abstract":"<div>\u0000 \u0000 <p>Obesity has become a growing concern globally as a leading risk factor for several chronic diseases such as diabetes, hypertension, cardiovascular disease and more. Many patients with obesity undergo metabolic and bariatric surgery (MBS) to lose weight and improve their comorbid conditions. Despite the generally accepted efficacy of these operations, some patients will not achieve substantial and sustained weight loss or will experience significant postoperative complications, leading to reoperation within 30 days after the first procedure. Using the 2022 American College of Surgeons Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program database, we selected patients who underwent either a laparoscopic sleeve gastrectomy (LSG) or a laparoscopic Roux-en-Y gastric bypass (LRYGB). Furthermore, we divided patients in each operation cohort into those who underwent reoperation within 30 days and those who did not. Patients who underwent a laparoscopic Roux-en-Y bypass experienced higher rates of reoperation (1.84%) compared to those undergoing an LSG (0.65%). In reoperation groups within both cohorts, comorbidities that commonly impact patients with obesity, such as diabetes, sleep apnoea and gastroesophageal reflux disease, were associated with higher rates of reoperation. As the prevalence of obesity increases worldwide, it is vital to understand the risk factors and complications associated with different types of MBS. Physicians choosing to utilise an LRYGB procedure over an LSG should do so while carefully considering the increased risk of reoperation.</p>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144093099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnic differences in weight loss during a clinical obesity management program","authors":"Jennifer Linchee Kuk,&nbsp;Parmis Mirzadeh,&nbsp;Sean Wharton","doi":"10.1111/cob.70022","DOIUrl":"10.1111/cob.70022","url":null,"abstract":"<p>To examine ethnic differences in how individuals respond to obesity management therapies, a retrospective chart review of the Wharton Medical Weight Management Clinic electronic medical records was used (<i>n</i> = 21 709; 14 695 patients with weight loss data). South and East Asian, Middle Eastern and Other ethnicities had a significantly lower body mass index (BMI) at enrollment than White adults (39.7 vs. 35.4–38.7 kg/m²), with higher or similar BMIs in Indigenous and Black adults (39.9–42.2 kg/m²). Whites, East Asians and Other Ethnicities had the greatest weight loss (4.3–4.9 kg), while Blacks (3.3 kg), Latin (3.0 kg), Middle Eastern (2.7 kg), and South Asians (3.5 kg) lost significantly less weight as compared to Whites (4.9 kg) (<i>p</i> &lt; .05). There were also weight loss differences between Black sub-groups. African American females lost the least weight (1.4 kg), while West Indian Black females lost much more weight (4.3 kg, <i>p</i> = .01). African American males also lost the least amount of weight (0.9 kg), while African Black males lost the most (7.4 kg, <i>p</i> = 0.01). There are differences in the weight loss achieved during a clinical obesity management program between individuals of various ethnicities.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.70022","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of maternal body mass index (BMI) and gestational weight gain on offspring's weight and BMI z-scores across the first 8 years of life","authors":"Zheng Lu,&nbsp;Iskander L. C. Shadid,&nbsp;Jhill Shah,&nbsp;Vincent J. Carey,&nbsp;Nancy Laranjo,&nbsp;George T. O'Connor,&nbsp;Robert S. Zeiger,&nbsp;Leonard Bacharier,&nbsp;Augusto A. Litonjua,&nbsp;Scott T. Weiss,&nbsp;Hooman Mirzakhani","doi":"10.1111/cob.70021","DOIUrl":"10.1111/cob.70021","url":null,"abstract":"<div>\u0000 \u0000 <p>While prior studies have linked maternal pre-pregnancy body mass index (BMI) and gestational weight gain (GWG) to birth weight and early childhood obesity, fewer have examined their joint effect on longitudinal growth trajectories, particularly standardized BMI <i>z</i>-scores through school age. We aimed to examine the relationship between maternal pre-pregnancy BMI, GWG and the trajectory of offspring's early-life weight, BMI <i>z</i>-scores and weight percentiles from birth to age 8. Linear mixed models were employed to assess the association between maternal pre-pregnancy BMI, GWG and children's standardized weight-for-age, BMI and length/height-for-age, adjusting for potential confounders. Data were analysed from 806 mother–child pairs from the Vitamin D Antenatal Asthma Reduction Trial, with children followed longitudinally from birth through 8 years of age. Our study demonstrated a significant association between maternal pre-pregnancy BMI and offspring weight-for-age and BMI <i>z</i>-score trajectories (<i>β</i> = .03, 95% confidence interval [CI]: 0.02–0.04 for both; <i>p</i> &lt; .001, respectively). Specifically, children born to mothers with pre-pregnancy BMI of 25–30 kg/m² or ≥30 kg/m² had significantly higher BMI <i>z</i>-scores (<i>β</i> = .15, 95% CI: 0.02–0.29; <i>p</i> = .03; <i>β</i> = .49, 95% CI: 0.33–0.64; <i>p</i> &lt; .001, respectively) compared to those with normal BMI. Maternal BMI was not significantly associated with the child's length/height. GWG was independently and positively associated with weight-for-age and BMI <i>z</i>-scores (<i>β</i> = .01, 95% CI: 0.002–0.015, <i>p</i> = .01 and <i>β</i> = .01, 95% CI: 0.01–0.02, <i>p</i> &lt; .001, respectively). Excessive GWG was linked to higher offspring weight-for-age and BMI <i>z</i>-scores from birth to 8 years (<i>β</i> = .20, 95% CI: 0.08–0.32; <i>β</i> = .19, 95% CI: 0.08–0.31; <i>p</i> = .001, respectively) compared to guideline-congruent or inadequate GWG. Achieving or maintaining a healthy BMI prior to pregnancy and adhering to GWG guidelines may help mitigate the risk of early childhood overweight or obesity.</p>\u0000 </div>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive dissonance for weight stigma reduction: The development and effect of a counter-attitudinal advocacy intervention","authors":"Vanessa Montemarano,&nbsp;Lamia Firasta,&nbsp;Jason Deska,&nbsp;Stephanie E. Cassin","doi":"10.1111/cob.70024","DOIUrl":"10.1111/cob.70024","url":null,"abstract":"<p>Weight stigmatization is persistent and pervasive, leading to numerous negative consequences. This study developed a weight stigma reduction intervention rooted in Cognitive Dissonance Theory aimed at reducing stigma towards individuals living in larger bodies. Undergraduate students (<i>N</i> = 325) were randomized to one of three conditions: Cognitive Dissonance (i.e., Written Advocacy or Written + Vocalized Advocacy) or Control. Participants in both Cognitive Dissonance conditions provided a written statement advocating for a proposal benefiting individuals living in larger bodies that would be somewhat costly to participants. Those in the Written + Vocalized Advocacy condition also vocalized their arguments to further enhance dissonance. It was hypothesized that compared to Controls, participants in both Cognitive Dissonance conditions would report reduced weight stigma and greater commitment to a prosocial action, with the strongest effects for the Written + Vocalized Advocacy condition. There was a significant reduction in weight stigma across all conditions, but minimal support for significant differences between conditions. Participants in the Cognitive Dissonance conditions did not commit significantly more hours towards the prosocial action compared to Controls. There was limited support that cognitive dissonance was induced. Future studies should pre-screen participants endorsing stronger weight stigma to help ensure they are advocating for a counter-attitudinal cause.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 5","pages":""},"PeriodicalIF":2.1,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.70024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Making do in the absence of specialist support: Exploring healthcare professionals' views, experiences and behaviours around long-term post-bariatric surgery follow-up care in the United Kingdom","authors":"Ross Watkins,&nbsp;Laura L. Jones,&nbsp;Kenneth Clare,&nbsp;Karen D. Coulman,&nbsp;Colin J. Greaves,&nbsp;Kate Jolly,&nbsp;Emma Shuttlewood,&nbsp;Helen M. Parretti","doi":"10.1111/cob.70016","DOIUrl":"10.1111/cob.70016","url":null,"abstract":"<p>Bariatric surgery is an effective treatment for obesity, but long-term can lead to health-related issues. Guidelines highlight the importance of long-term post-bariatric surgery follow-up. However, in the UK, there is currently no specific funding to support the delivery of this care. Our aim was to understand the views and experiences of healthcare professionals (HCPs) around long-term post-bariatric surgery follow-up, and barriers and enablers to care. Semi-structured interviews with HCPs in UK primary care or specialist weight management services were conducted. The topic guide was theoretically informed by the Capability-Opportunity-Motivation-Behaviour model and the Theoretical Domains Framework. Thematic analysis was undertaken. Twenty-six HCPs were interviewed. Three core themes were interpreted: <i>Existing Challenges</i>, <i>Mediating Factors</i> and <i>Future Directions</i>. While there was agreement on the need for long-term support, current provision was variable and hampered by a paucity of referral options. Follow-up care could be contingent upon the patients' surgical pathway and the culture and expertise within the general practitioner surgery. Participants discussed potential ways to improve care, including using technology, adapting approaches used in other chronic conditions, shared care models and harnessing the potential for peer-based support to improve wellbeing and quality of life. Healthcare professionals' views and experiences shared in this study highlight the complex issues associated with long-term bariatric surgery follow-up. The findings will inform future research to design and implement care pathways that are urgently needed to improve service provision for these patients.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 4","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.70016","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}