{"title":"Is bariatric surgery a crime? A systematic review and meta-analysis of postoperative psychiatric symptoms and eating disorders.","authors":"Bushra Albadareen, Ahmed AlBadareen","doi":"10.1111/cob.70017","DOIUrl":"https://doi.org/10.1111/cob.70017","url":null,"abstract":"<p><p>Bariatric surgery can lead to significant weight loss and improved physical health. Still, it often also brings about complex psychological effects, including changes in self-esteem, body image and emotional well-being that require careful monitoring and support. This systematic review with meta-analysis aims to analyse the relationship between bariatric surgery and postoperative improvement in psychiatric and eating disorders. MEDLINE, EMBASE, COCHRANE Library and other specialized databases were searched in July 2024. Observational studies included individuals who had undergone any bariatric surgical treatment with a preoperative evaluation of eating disorders, depression and anxiety and at a postoperative measure of the same variables selected. Thirteen studies that met the eligibility criteria were included for qualitative synthesis and eight studies for meta-analysis. Two reviewers independently screened for eligibility. The mean difference was calculated using the random-effects model. Bariatric surgery was found to be effective in improving eating disorders (-0.81%, 95% CI -1.61 to -0.05; I2 = 98%, p < .05), depression (-0.56, 95% CI -1.09 to -0.04, I2 = 97%, p < .03) and anxiety (-0.74, 95% CI -1.17 to -0.31, I2 = 94%, p < .00). The literature reveals high heterogeneity between studies, particularly in assessing psychological factors, with a common reliance on self-reported questionnaires rather than gold-standard assessments. Nonetheless, based on the findings of this study, there was a genuine effect on eating disorders, depression and anxiety when those participants underwent bariatric surgery.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":" ","pages":"e70017"},"PeriodicalIF":2.2,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143957023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abraish Ali, Asad Ali Siddiqui, Muhammad Shariq Usman, Izza Shahid, Muhammad Shahzeb Khan, Prinka Perswani
{"title":"Effect of glucagon-like peptide 1 receptor agonists on systolic blood pressure in patients with obesity, with or without diabetes: A systematic review and network meta-analysis.","authors":"Abraish Ali, Asad Ali Siddiqui, Muhammad Shariq Usman, Izza Shahid, Muhammad Shahzeb Khan, Prinka Perswani","doi":"10.1111/cob.70012","DOIUrl":"https://doi.org/10.1111/cob.70012","url":null,"abstract":"<p><p>The effect of glucagon-like peptide 1 receptor agonists (GLP-1RAs) on systolic blood pressure (SBP) in patients with obesity with or without diabetes remains unclear. The aim was to compare the effect of different drug-dose combinations of GLP-1RAs on SBP. The secondary aim was to assess whether changes in SBP with GLP-1RAs are associated with weight change. MEDLINE and Cochrane were searched until January 2022 for randomized control trials (RCTs) on patients with obesity, evaluating the impact of semaglutide, liraglutide, efpeglenatide, or exenatide on SBP. Separate analyses were done for trials with and without diabetes. Multivariate meta-regression assessed if SBP changes with GLP-1RA varied based on weight change or follow-up duration. Thirty-five RCTs were included. Follow-up duration ranged from 12 to 68 weeks for T2DM and 12-56 weeks for non-T2DM patients. GLP-1RAs significantly lowered SBP for all patients (MD = -3.14 [-3.60; -2.68]). Subgroup analysis showed a significantly greater difference in SBP reduction for patients without diabetes (-3.80 [-4.24; -3.37]) when compared with patients with diabetes (-2.13 [-3.27; -1.00]). Among patients with diabetes, liraglutide < 2 mg OD showed the greatest reduction in SBP (-3.78 [-6.27; -1.28]), while efpeglenatide ≤ 6 mg QW showed the greatest reduction in SBP (-6.00 [-9.89; -2.11]) in patients without diabetes. GLP-1RAs result in mild reductions in SBP in patients with obesity. The change in SBP varies only slightly by the drug-dose combination and appears to be related to the amount of weight loss.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":" ","pages":"e70012"},"PeriodicalIF":2.2,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadia Botros, Melina T Czymoniewicz-Klippel, Vera van de Scheur, Laura N Deden, Elske M van den Berg, Eric J Hazebroek
{"title":"How well does it fit? Process evaluation of a multidisciplinary pre- and postoperative metabolic bariatric surgery support programme: A patients' perspective.","authors":"Nadia Botros, Melina T Czymoniewicz-Klippel, Vera van de Scheur, Laura N Deden, Elske M van den Berg, Eric J Hazebroek","doi":"10.1111/cob.70006","DOIUrl":"https://doi.org/10.1111/cob.70006","url":null,"abstract":"<p><p>Multidisciplinary support can help patients improve health and cope with changes after metabolic and bariatric surgery (MBS). However, there is uncertainty regarding what intervention components, delivery methods and intensity are effective. To understand how intervention effects are achieved, we performed a process evaluation of a 15-session pre- and post-MBS programme comprising medical, dietary and psychological interventions delivered via group sessions until 9 months postsurgery. The evaluation examined programme relevance, perceived fit and practicability ('appropriateness') and satisfaction with content and delivery ('acceptability'). Interviews (n = 11) and focus groups (n = 2) were performed with 21 patients in different programme phases. Programme fidelity was assessed using administrative data on attendance in 1.396 patients. Presurgery, practicing with postoperative recommendations and multiple social components, was described as useful. Although participants found several postoperative components helpful (e.g. meal planning), the perceived fit was lower due to group delivery, session spacing and varying needs. Attended programme time postsurgery was lower than presurgery. Individual needs varied in terms of support intensity and type, and by gender, age and surgery type. Participants recommended greater session spacing, as maintaining behaviours >1 year postsurgery was expected to be most challenging. Participants requested additional information on negative lived experiences, exercise and coping with various postoperative changes. Programme fit can be improved by taking patients' varying needs into account in a flexible programme, with a duration beyond the first postoperative year, and more attention to negative lived experiences, exercise and coping with changes.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":" ","pages":"e70006"},"PeriodicalIF":2.2,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143981313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Amir Yazdanparast, Sean Wharton, Hala Tamim, Alison K Macpherson, Jennifer L Kuk
{"title":"The association of motivational factors with weight loss and treatment time in a publicly funded weight management clinic.","authors":"Amir Yazdanparast, Sean Wharton, Hala Tamim, Alison K Macpherson, Jennifer L Kuk","doi":"10.1111/cob.70014","DOIUrl":"https://doi.org/10.1111/cob.70014","url":null,"abstract":"<p><p>The objective of the study is to explore differences in weight loss (WL) and treatment time with having health, mobility, and/or aesthetics motivations for attempting WL. Data from 7540 adults with overweight or obesity who participated in a publicly funded weight management programme at the Wharton Medical Clinic were analysed. Patients' WL motivations were categorised into six groups: Health only; Health and Aesthetics; Health and Mobility; Health, Mobility and Aesthetics; No Health; and None. Women with Health, Mobility and Aesthetics or No Health motivations had marginally higher WL goals compared to other groups, with no differences in men. Men with Health and Aesthetics or Health and Mobility motivations showed marginally higher 6-month attendance rates. Men who discontinued after one visit were 40% less likely to have a Health and Aesthetics motivation as opposed to Health only, compared to those who continued. No differences were observed in WL between motivation groups in either sex. No correlation was found between WL goals and WL attained. Only weak correlations between treatment time and WL were observed across most motivation groups. Despite small differences in treatment time and WL goals, motivations for attempting WL were not significantly associated with differences in the WL achieved.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":" ","pages":"e70014"},"PeriodicalIF":2.2,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143810064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Early obesity risk prediction via non-dietary lifestyle factors using machine learning approaches.","authors":"Ker Ming Seaw, Melvin Khee Shing Leow, Xinyan Bi","doi":"10.1111/cob.70011","DOIUrl":"https://doi.org/10.1111/cob.70011","url":null,"abstract":"<p><p>Obesity poses a significant health threat, contributing to the development of noncommunicable diseases (NCDs). Early identification of individuals at higher risk for obesity is crucial for implementing effective prevention strategies. This study explores the viability of non-dietary factors such as lifestyle, family history, and demographics as predictors of obesity risk. The dataset comprised 1068 males and 1043 females, aged between 14 and 61 years. Only non-dietary factors were used to build the machine learning models, including decision tree, random forest, support vector classification (SVC), k-nearest neighbour (KNN), and Gaussian Naïve Bayes (GNB). Random forest emerged as the optimal model, demonstrating 66.9% test accuracy, 66.4% precision, 66.9% recall, 66.4% F1-score, 94.5% specificity and 92.3% area under the receiver operating characteristic curve (AUC-ROC). Variability of the models' performance was also evaluated through bootstrapping. Lifestyle factors, while less impactful than family history and demographics, also contributed to predictive power. This indicates the potential for predicting obesity while relying less on dietary data, paving the way for future studies to refine predictive models. This could play a crucial role in identifying lifestyle factors as predictors of obesity, thereby preventing and intervening early to address obesity-related complications.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":" ","pages":"e70011"},"PeriodicalIF":2.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143779296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Considerations in the treatment of individuals with obesity and periodontitis","authors":"Abigail S. Q. Cheong, Jean E. Suvan","doi":"10.1111/cob.70002","DOIUrl":"10.1111/cob.70002","url":null,"abstract":"<p>Two common non-communicable diseases, obesity and periodontitis, are responsible for and affected by systemic inflammation, sharing common risk factors and mechanistic pathways. Periodontitis is an irreversible immune-mediated inflammatory disease of hard and soft tissue supporting teeth. If left untreated, periodontitis can lead to tooth loss, affecting food choices and healthy eating, therefore affecting overall health. Obesity is an independent predictive factor for worsened periodontal inflammation, increased onset, progression, severity, and recurrence of infection, as well as delayed wound healing. Thus, managing obesity and associated metabolic dysfunctions may improve periodontal therapy outcomes. The chronic inflammatory state of obesity impairs immune regulation exacerbating the inflammatory gingival tissue destruction of periodontitis, which can also systemically contribute to inflammatory mediators. Furthermore, bariatric surgeons and dietitians should educate patients with obesity regarding the risk of elevated caries, xerostomia, and periodontitis risk from acid reflux and frequent food intake. Non-dental healthcare professionals should recognise periodontal disease signs to prompt dental referral when warranted. Asking patients about recent dental visits promotes patient involvement in cross-discipline dialogue to enhance patient care coordination between medicine and dentistry. This article discusses the association between these two diseases, the challenges of achieving optimal periodontal treatment outcomes, and the clinical strategies to enhance holistic care. It also explores oral health considerations in dietary and surgical interventions in the treatment of obesity.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":"15 3","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cob.70002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143708917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Jaensson, Karuna Dahlberg, Yang Cao, Anders Thorell, Johanna Österberg, Ulrica Nilsson, Erik Stenberg
{"title":"Impact of health literacy and general self-efficacy on surgical outcomes 2 years after bariatric surgery.","authors":"Maria Jaensson, Karuna Dahlberg, Yang Cao, Anders Thorell, Johanna Österberg, Ulrica Nilsson, Erik Stenberg","doi":"10.1111/cob.70009","DOIUrl":"https://doi.org/10.1111/cob.70009","url":null,"abstract":"<p><p>After bariatric surgery, adherence to lifestyle recommendations is crucial. Health literacy and self-efficacy may impact recovery after surgery. In this multicentre study performed in three hospitals in Sweden, we evaluated any relation between preoperative health literacy and general self-efficacy on the one side and weight loss, health-related quality of life, length of stay, and complications up to 2 years after bariatric surgery on the other. Of 686 included patients, 56% (n = 382) had limited functional health literacy, 42% (n = 278) had limited communicative and critical health literacy, and 40% (n = 266) reported low general self-efficacy. Preoperative functional, communicative and critical health literacy, and general self-efficacy were not associated with the degree of weight loss at 1 or 2 years after surgery. However, limited health literacy and low general self-efficacy scores were associated with both reduced quality of life and obesity-related problems postoperatively. Further, a higher proportion of those with inadequate health literacy had a prolonged length of stay. Although patients with limited health literacy and self-efficacy may experience similar maximum weight loss after bariatric surgery as other patients, they still might have reduced health-related quality of life in terms of obesity-related problems. Increased awareness of this association as well as patient-centered support before and after bariatric surgery may be of benefit.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":" ","pages":"e70009"},"PeriodicalIF":2.2,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143584886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A B M Kamrul-Hasan, Joseph M Pappachan, Lakshmi Nagendra, Hamid Ashraf, Deep Dutta, Saptarshi Bhattacharya, Nitin Kapoor
{"title":"Metabolic outcomes of bariatric surgery versus lifestyle intervention in adolescents with severe obesity: A systematic review and meta-analysis.","authors":"A B M Kamrul-Hasan, Joseph M Pappachan, Lakshmi Nagendra, Hamid Ashraf, Deep Dutta, Saptarshi Bhattacharya, Nitin Kapoor","doi":"10.1111/cob.70008","DOIUrl":"https://doi.org/10.1111/cob.70008","url":null,"abstract":"<p><p>Data from clinical trials evaluating the effectiveness and safety of metabolic and bariatric surgery (MBS) compared to lifestyle modifications (LSM) in children and adolescents with obesity are scarce. This systematic review and meta-analysis (SRM) sought to fill this knowledge gap. Randomised or non-randomised trials spanning at least one-year involving children and adolescents with severe obesity receiving any form of MBS in the intervention group and LSM for weight loss in the control group were systematically searched through electronic databases. This SRM adhered to the guidelines outlined in the Cochrane Handbook for Systematic Reviews of Interventions and the PRISMA checklists. The primary outcome of interest was the change in body weight from the baseline. Five trials (three randomised, open-label and two non-randomised) with 1-2 years follow-up durations were analysed, including 367 participants aged 10-19 years. MBS resulted in greater reductions in body weight (mean difference [MD] -25.83 kg, 95% confidence interval [CI] [-36.91, -14.75], p < .00001) and per cent body weight (MD -24.54%, 95% CI [-33.19, -15.89], p < .00001) compared to LSM. Furthermore, MBS outperformed LSM in reducing body mass index (BMI), BMI z-score, waist circumference, glycated haemoglobin, fasting plasma glucose, insulin resistance, triglycerides, alanine aminotransferase, high sensitivity C-reactive protein and an overall improvement of physical functioning and quality of life. The safety profile was comparable between the two groups; however, data was scarce. Larger, longer-term trials that include multinational and multiethnic representation are essential for making solid clinical practice recommendations regarding MBS for children with obesity.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":" ","pages":"e70008"},"PeriodicalIF":2.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maya E Joseph, Nisha Mathews, Lydia H Albuquerque, Peter Chen
{"title":"An exploration of self-perception of weight status, weight-related variables, and preferences for weight management strategies among South Asians in the US.","authors":"Maya E Joseph, Nisha Mathews, Lydia H Albuquerque, Peter Chen","doi":"10.1111/cob.70007","DOIUrl":"https://doi.org/10.1111/cob.70007","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to explore the relationships between self-perception of weight status, weight-related variables, and weight management preferences of South Asians (SA) to assist in building culturally tailored interventions for obesity management.</p><p><strong>Methods: </strong>This was a cross-sectional, descriptive, and correlational study. The sample consisted of 272 South Asians over 18 years of age. Data analyses included descriptive and inferential statistics.</p><p><strong>Results: </strong>Based on ethnic-specific BMI criteria, 88.6% of participants were overweight/obese, and 53.5% had abdominal obesity. Among participants, 37% misperceived their weight status. Older individuals had lower chances of accepting weight loss medications (OR = 0.96, 95%CI: 0.94-0.99), while overweight/obese participants had lower odds of accepting weight management surgery (OR = 0.34, 95%CI: 0.13-0.85). The odds of accepting medication therapy were higher if the healthcare provider discussed weight status with them (OR = 1.84, 95% CI:1.06-3.21). Finally, compared to their counterparts, men, those with overweight/obesity, and those with abdominal obesity had 66%, 65%, and 49% lower odds of accurately perceiving their weight status, respectively.</p><p><strong>Conclusion: </strong>This study highlights the high prevalence of overweight and obesity, the misperceptions of weight status, the need for provider involvement in care, and the specific subgroups of SAs with more misperceptions of weight status.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":" ","pages":"e70007"},"PeriodicalIF":2.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rebecca L Pearl, Laurie C Groshon, Marian Hernandez, Caroline Bach, Erica M LaFata, Hannah F Fitterman-Harris, Dakota L Leget, Miriam Sheynblyum, Thomas A Wadden
{"title":"Characterising first, recent and worst experiences of weight stigma in a clinical sample of adults with high body weight and high internalised stigma.","authors":"Rebecca L Pearl, Laurie C Groshon, Marian Hernandez, Caroline Bach, Erica M LaFata, Hannah F Fitterman-Harris, Dakota L Leget, Miriam Sheynblyum, Thomas A Wadden","doi":"10.1111/cob.70005","DOIUrl":"https://doi.org/10.1111/cob.70005","url":null,"abstract":"<p><p>This research aimed to systematically characterise experiences of weight stigma and their impacts among weight-loss treatment-seeking adults with high body weight and high levels of internalised weight stigma. Participants recruited for two clinical trials completed a semi-structured interview about weight stigma (Study 1 n = 84, M<sub>age</sub> = 47.8 ± 11.2 years, 83.3% women, 67.9% Black; Study 2 n = 129, M<sub>age</sub> = 50.0 ± 12.2 years, 88.4% women, 65.1% White). Study 1 focused on first and most recent experiences of weight-based teasing, bullying, discrimination and unfair treatment, and Study 2 focused on the worst examples of these experiences; participants in both studies also identified their overall worst experiences. Participants reported the age at which the experiences occurred and rated (1-5) how upsetting they were. Interview responses were coded for interpersonal sources of weight stigma and impacts of these experiences. Across studies, weight teasing was the most commonly reported experience of weight stigma and the most frequently identified worst experience. Family members were the most commonly identified interpersonal source of weight stigma. Weight stigma experiences were reported across the lifespan and were predominantly described as having negative emotional impacts. Findings provide insights into the types and characteristics of weight stigma experiences that may contribute to the internalisation of this stigma and other adverse consequences.</p>","PeriodicalId":10399,"journal":{"name":"Clinical Obesity","volume":" ","pages":"e70005"},"PeriodicalIF":2.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}