Clinics in dermatology最新文献_第9页

Jewish women in dermatology 皮肤科中的犹太女性

IF 2.3 4区医学

Clinics in dermatology Pub Date : 2025-01-01 DOI: 10.1016/j.clindermatol.2024.08.009

Tristi M. Edwards MD , Nicolas Andre MD , Leonard J. Hoenig MD , Eve J. Lowenstein MD,PhD

引用次数: 0

Commentary: Current views on melanoma: I 目前对黑色素瘤的看法：I.

IF 2.3 4区医学

Clinics in dermatology Pub Date : 2025-01-01 DOI: 10.1016/j.clindermatol.2024.09.011

Jane M. Grant-Kels MD, FAAD

引用次数: 0

Melanoma in patients with skin of color

IF 2.3 4区医学

Clinics in dermatology Pub Date : 2025-01-01 DOI: 10.1016/j.clindermatol.2025.01.014

Lauren Skudalski MD , Patrick McMullan PhD , Jane M. Grant-Kels MD

引用次数: 0

Fitzpatrick skin type and relationship to ocular melanoma

IF 2.3 4区医学

Clinics in dermatology Pub Date : 2025-01-01 DOI: 10.1016/j.clindermatol.2025.01.016

Irwin Leventer BA, Kevin R. Card BS, Carol L. Shields MD

{"title":"Fitzpatrick skin type and relationship to ocular melanoma","authors":"Irwin Leventer BA, Kevin R. Card BS, Carol L. Shields MD","doi":"10.1016/j.clindermatol.2025.01.016","DOIUrl":"10.1016/j.clindermatol.2025.01.016","url":null,"abstract":"<div><div>Fitzpatrick Skin Type (FST) is a classification for skin color, ranging from FST I (lightest skin tone) to FST VI (darkest skin tone), used to study risk and outcomes of cutaneous melanoma. Ocular melanoma includes primary melanoma in the eye region, including the conjunctiva and the uvea. There is little literature on the relationship of FST with ocular melanoma. Regarding conjunctival melanoma, one study evaluated 540 eyes with conjunctival melanoma and found that patients most often demonstrated FST I or II (85%). A comparison between FST I vs. II vs. III-VI showed that FST did not impact 5-year outcomes of metastasis or death. Regarding uveal melanoma, three separate studies evaluated 854 eyes with uveal melanoma and FST data. The first study explored the relationship of FST (FST I vs. II vs. III-V) with iris pigmentation. Patients with FST III-V and brown iris color were found to have larger mean tumor thickness (<em>p</em>=0.003) and basal diameter (<em>p</em>=0.001). The second study identified that patients with FST I demonstrated more high-grade tumor genetic mutations (odds ratio (OR) 2.34, <em>p</em>=0.002) whereas those with FST III-V demonstrated low-grade tumor genetic mutations (OR 2.26, <em>p</em>=0.002). The third report revealed patients with FST I showed greatest 10-year risk for metastasis (25% vs. 15% vs. 14%, <em>p</em>=0.02) and death (9% vs. 3% vs. 4%, <em>p</em>=0.04), perhaps related to advanced tumor genetic mutations. Herein, we summarize the published literature on the relationship of FST in 540 eyes with conjunctival melanoma and in 854 eyes with uveal melanoma.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"43 1","pages":"Pages 56-63"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparison between national and international melanoma skin cancer treatment guidelines

IF 2.3 4区医学

Clinics in dermatology Pub Date : 2025-01-01 DOI: 10.1016/j.clindermatol.2025.01.011

Michele Rudari MD, Raphael Brooks MD, Adrian Dragu MD, Seyed Arash Alawi MD

{"title":"A comparison between national and international melanoma skin cancer treatment guidelines","authors":"Michele Rudari MD, Raphael Brooks MD, Adrian Dragu MD, Seyed Arash Alawi MD","doi":"10.1016/j.clindermatol.2025.01.011","DOIUrl":"10.1016/j.clindermatol.2025.01.011","url":null,"abstract":"<div><div>We analyzed nationally and internationally recognized clinical practice guidelines for melanoma skin cancer to compare their therapeutic and diagnostic strategies. We considered internationally recognized melanoma skin cancer guidelines from the United States (American Academy of Dermatology), Germany (S3-Leitlinie Melanom), and Australia (Cancer Council Australia). We found widespread agreement in diagnostic approaches for cutaneous melanoma, especially in surgical intervention and therapy for regional lymph node involvement. The first difference encountered was the German guidelines advising lymph node ultrasound from stage IB, whereas the US and Australian guidelines recommend it only when sentinel lymph node biopsy is not possible or denied by the patient. A different approach was observed in relation to the assessment of tumor marker S100B in stage III of cutaneous melanoma. The German guidelines advocate for the incorporation of S100B in baseline surveillance, whereas Australia and the United States do not. Although there were some further minor differences, apart from the aforementioned two, all three guidelines under scrutiny exhibit a substantial level of agreement.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"43 1","pages":"Pages 24-28"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Melanoma in older adolescents and young adult patients: A population-based analysis of the Surveillance, Epidemiology, and End Results Program database from 2000 to 2019

IF 2.3 4区医学

Clinics in dermatology Pub Date : 2025-01-01 DOI: 10.1016/j.clindermatol.2025.01.013

Yue Wang MM , Hailiang Xu MM , Long Ge MM , Nan Zhang MM

{"title":"Melanoma in older adolescents and young adult patients: A population-based analysis of the Surveillance, Epidemiology, and End Results Program database from 2000 to 2019","authors":"Yue Wang MM , Hailiang Xu MM , Long Ge MM , Nan Zhang MM","doi":"10.1016/j.clindermatol.2025.01.013","DOIUrl":"10.1016/j.clindermatol.2025.01.013","url":null,"abstract":"<div><div>Epidemiologic characteristics of melanoma in older adolescents and young adult (AYA) patients aged 15 to 39 years are unknown. We examined the epidemiologic characteristics of melanoma in AYA patients and then extracted demographic and pathologic data for this retrospective cohort study from the Surveillance, Epidemiology, and End Results database (2000-2019). Cox regression analyses were used to assess the risk of all-cause death, cancer-specific death, and second primary malignancy. A total of 2,835 AYA patients with melanoma were included, of whom 926 (32.66%) had a second primary malignancy. The incidence of melanoma in AYA patients decreased from 0.9 per 1,000,000 person-year in 2000 to 0.2 per 1,000,000 person-year in 2019, with an average annual percentage change of −6.3% (95% CI, −7.2% to −5.3%). Melanoma patients who were darker skinned (Black) (hazard ratio, 3.794; 95% CI, 1.382-10.412) were associated with an increased risk of second primary malignancies, whereas patients with a Breslow depth of >4 mm (hazard ratio, 0.517; 95% CI, 0.379-0.706), melanoma site on the trunk (hazard ratio, 0.700; 95% CI, 0.536-0.915), and extremities (hazard ratio, 0.760; 95% CI, 0.585-0.988) were associated with a decreased risk of second primary malignancies. This study may provide statistical data on the epidemiologic characteristics of melanoma in AYA patients.</div></div>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":"43 1","pages":"Pages 36-47"},"PeriodicalIF":2.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Navigating the ethics of predatory journals and processing fees in dermatology. 在皮肤病学掠夺性期刊和处理费用的伦理导航。

IF 2.3 4区医学

Clinics in dermatology Pub Date : 2024-12-27 DOI: 10.1016/j.clindermatol.2024.12.019

Sowmya Ravi, Albert E Zhou, Brett Sloan, Lionel Bercovitch, Jane M Grant-Kels

{"title":"Navigating the ethics of predatory journals and processing fees in dermatology.","authors":"Sowmya Ravi, Albert E Zhou, Brett Sloan, Lionel Bercovitch, Jane M Grant-Kels","doi":"10.1016/j.clindermatol.2024.12.019","DOIUrl":"10.1016/j.clindermatol.2024.12.019","url":null,"abstract":"<p><p>The rise of predatory journals has created a pressing ethical dilemma in academic publishing, exploiting urgency of researchers to publish while prioritizing profits over quality. These journals, characterized by deceptive practices and inadequate peer review, often undermine scientific integrity and disproportionately affect early-career academicians and those from underfunded institutions. Although open access publishing aims to democratize knowledge, its reliance on high processing charges poses accessibility challenges, particularly in resource-limited settings. This issue extends beyond predatory journals, as even reputable journals often impose substantial high processing charges, creating a broader crisis of inequitable access to publishing research findings. The implications of these exploitative practices are far-reaching, potentially compromising patient care (via publication of inferior papers in predatory journals), fostering researcher burnout, and hindering global collaboration. Addressing this requires systemic reform, including increased transparency, reduced costs, expanded funding, and promoting community-led publishing platforms. Ethical publishing practices must prioritize inclusivity and the dissemination of knowledge to preserve the integrity and accessibility of academic research.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biopsy Quotas: Ethical Implications of Financial Incentives and Penalties on Dermatologic Care Providers. 活检配额：对皮肤护理提供者的经济激励和处罚的伦理含义。

IF 2.3 4区医学

Clinics in dermatology Pub Date : 2024-12-27 DOI: 10.1016/j.clindermatol.2024.12.020

Timothy Klufas, Ayushya Ajmani, Shannon Hanggodo, Albert E Zhou, Hao Feng, Jane M Grant-Kels

{"title":"Biopsy Quotas: Ethical Implications of Financial Incentives and Penalties on Dermatologic Care Providers.","authors":"Timothy Klufas, Ayushya Ajmani, Shannon Hanggodo, Albert E Zhou, Hao Feng, Jane M Grant-Kels","doi":"10.1016/j.clindermatol.2024.12.020","DOIUrl":"10.1016/j.clindermatol.2024.12.020","url":null,"abstract":"<p><p>The evolution of health care payment models has profoundly influenced clinical practices and physician decision-making. Although fee-for-service models incentivize procedural volume, systems based on relative value units have introduced standardized metrics to compensate physicians based on care complexity and workload. As corporations increasingly own health care, financial incentives such as relative value units and procedural quotas raise ethical concerns. Quotas intended to boost efficiency and profitability may prompt corporate entities to pressure clinicians to meet procedural targets, potentially prioritizing financial performance over patient welfare. Such pressures risk leading to overtreatment and unnecessary procedures, challenging the principles of nonmaleficence and beneficence, especially when less invasive or noninvasive alternatives are clinically viable. Ethical frameworks, including the American Medical Association Code of Medical Ethics, emphasize the need for compensation models that align with clinical judgment and support patient-centered care.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142902739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impersonating expertise: The ethics of misleading dermatology advertising. 冒充专家：误导皮肤科广告的伦理。

IF 2.3 4区医学

Clinics in dermatology Pub Date : 2024-12-03 DOI: 10.1016/j.clindermatol.2024.11.005

Akash Rau, Andrew Z Li, Julia Giordano, Jane M Grant-Kels, Zelma C Chiesa Fuxench

引用次数: 0

The church spire sign. 教堂尖顶标志。

IF 2.3 4区医学

Clinics in dermatology Pub Date : 2024-11-24 DOI: 10.1016/j.clindermatol.2024.11.003

Uwe Wollina, Leonard J Hoenig, Sophie Walter, Lawrence Charles Parish

引用次数: 0