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The Comorbidities of Hidradenitis Suppurativa. 化脓性汗腺炎的合并症。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-05-23 DOI: 10.1016/j.clindermatol.2025.05.009
Özge Aşkın, Zeynep Altan Ferhatoğlu, Defne Özkoca, Seher Küçükoğlu Cesur, Yalçın Tüzün
{"title":"The Comorbidities of Hidradenitis Suppurativa.","authors":"Özge Aşkın, Zeynep Altan Ferhatoğlu, Defne Özkoca, Seher Küçükoğlu Cesur, Yalçın Tüzün","doi":"10.1016/j.clindermatol.2025.05.009","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.05.009","url":null,"abstract":"<p><p>Hidradenitis suppurativa (HS) is a chronic inflammatory disease that drammatically decreases the quality of life for afflicted patients. A number of factors may co-exist with HS: stigmatization, social isolation, tobacco use, alcohol abuse, suicidal ideation, depression, other psychiatric disorders, plus medical comorbidities that include obesity, diabetes mellitus, hypertension, dyslipidemia, metabolic syndrome, coronary artery disease, and polycystic ovarian syndrome may coexist with hidradenitis suppurativa. These comorbidities should be kept in mind while planning the treatment. A rare but important long-term complication of hidradenitis suppurativa is squamous cell cancer; men with perianal, gluteal, or perineal lesions are at increased risk, and multiple biopsies should be taken in case of any suspicious lesions.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact and Ethical Consequences of Tuition-Free Medical Schools on Improving Diversity in Healthcare. 免学费医学院对改善医疗保健多样性的影响和伦理后果。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-05-23 DOI: 10.1016/j.clindermatol.2025.05.018
Albert E Zhou, Trevor Sutton, Jeffrey Hines, Steven Angus, Hao Feng, Brett Sloan, Jane M Grant-Kels
{"title":"The Impact and Ethical Consequences of Tuition-Free Medical Schools on Improving Diversity in Healthcare.","authors":"Albert E Zhou, Trevor Sutton, Jeffrey Hines, Steven Angus, Hao Feng, Brett Sloan, Jane M Grant-Kels","doi":"10.1016/j.clindermatol.2025.05.018","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.05.018","url":null,"abstract":"<p><p>Tuition-free medical education has been promoted as a solution to rising student debt and a strategy to improve diversity in the physician workforce. Several institutions across the United States have implemented full-tuition scholarships with the stated aim of increasing access, encouraging primary care careers, and reducing healthcare disparities; however, early evidence suggests these initiatives may have unintended consequences. We examine the ethical and impact of tuition-free medical education on diversity and specialty choice. To realize the full potential of tuition-free education, policies must be coupled with need-based support, expanded public funding, and holistic admissions practices. Institutions should critically evaluate how their missions, resources, and partnerships promote equitable access. Despite its positive intentions, tuition-free models risk benefiting the already privileged and widening the gap they were designed to close.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Poems by Nature: A Testimony to Early English Garden Art in Saxony. 自然之诗：萨克森早期英国园林艺术的见证。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-05-22 DOI: 10.1016/j.clindermatol.2025.05.017
Uwe Wollina
{"title":"Poems by Nature: A Testimony to Early English Garden Art in Saxony.","authors":"Uwe Wollina","doi":"10.1016/j.clindermatol.2025.05.017","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.05.017","url":null,"abstract":"<p><p>Landscape as arranged nature reached its preliminary climax in the 18th century with the concept of the English Garden. One of the earliest German examples of an English garden can be found in the Saxonian valley of Seifersdorf, created by Countess Christina von Brühl between 1781 and 1791. Landscape was designed as a source of health, well-being, mental stimulation, and enlightened education. In context with aspects of modern spatial planning, the oeuvre of Countess von Brühl appears under a new light, i.e. as an example of an aesthetic-therapeutic landscape.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
THE PSYCHOSOCIAL EFFECTS OF HIDRADENITIS SUPPURATIVA. 化脓性汗腺炎的社会心理影响。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-05-15 DOI: 10.1016/j.clindermatol.2025.05.007
Paola Đurinec, Zrinka Bukvić Mokos, Branka Marinović
{"title":"THE PSYCHOSOCIAL EFFECTS OF HIDRADENITIS SUPPURATIVA.","authors":"Paola Đurinec, Zrinka Bukvić Mokos, Branka Marinović","doi":"10.1016/j.clindermatol.2025.05.007","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.05.007","url":null,"abstract":"<p><p>Hidradenitis suppurativa (HS) is a chronic debilitating skin disease with a tremendous impact on the quality of life. Despite the development of new treatment modalities, consistent remission rates are still hard and sometimes impossible to achieve. Delayed diagnosis, misdiagnosis, and lack of access to adequate medical care are important issues. Poor Quality of Life (QoL) of HS patients, already proven in many studies, is most strongly influenced by physical factors along with depression and anxiety, negative body image, low self-esteem, sexual dysfunction, and impairment of ability to work. Targeting these psychosocial aspects has a great potential to improve care for HS patients. Only a holistic approach can lead to significant improvement, allowing people with HS to live more fulfilled lives.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hidradenitis suppurativa in children and adolescents. 儿童及青少年化脓性汗腺炎。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-05-15 DOI: 10.1016/j.clindermatol.2025.05.005
Nives Pustisek, Assist Prof Suzana Ozanic Bulic, Assist Prof Arnes Resic, Luka Bulic, Eva Brenner
{"title":"Hidradenitis suppurativa in children and adolescents.","authors":"Nives Pustisek, Assist Prof Suzana Ozanic Bulic, Assist Prof Arnes Resic, Luka Bulic, Eva Brenner","doi":"10.1016/j.clindermatol.2025.05.005","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.05.005","url":null,"abstract":"<p><p>Hidradenitis suppurativa in children and adolescents share similar clinical features and distribution of lesions as in adult patients, causing significant physical and psychologic burdens. The disease is associated with several comorbidities; therefore, a diagnostic work-up should include screening for metabolic, psychiatric, autoimmune, and hyperandrogenic comorbidities. The goal of the treatment is to alleviate pain, minimize inflammation and scarring, and prevent disease progression. Currently, there are no hidradenitis suppurativa treatment guidelines for children and adolescents, and the treatment primarily relies on the management of hidradenitis suppurativa in adults. We summarize the current information about the epidemiology, pathogenesis, clinical features, comorbidities, diagnostic work-up, and treatment options for children and adolescents afflicted with hidradenitis suppurativa.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovations in maternal-fetal dermatology: A focus on artificial intelligence-driven diagnostics, global disparities, and transformative care. 母胎皮肤科的创新：专注于人工智能驱动的诊断、全球差异和变革性护理。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-05-14 DOI: 10.1016/j.clindermatol.2025.05.013
Diala Ra'Ed Kamal Kakish, Sereen Abdel Nour, Raghad Abusalha, Heba Yousef Mustafa, Sanjana Suresh, George Kroumpouzos
{"title":"Innovations in maternal-fetal dermatology: A focus on artificial intelligence-driven diagnostics, global disparities, and transformative care.","authors":"Diala Ra'Ed Kamal Kakish, Sereen Abdel Nour, Raghad Abusalha, Heba Yousef Mustafa, Sanjana Suresh, George Kroumpouzos","doi":"10.1016/j.clindermatol.2025.05.013","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.05.013","url":null,"abstract":"<p><p>Pregnancy-associated dermatologic conditions emerge from intricate hormonal, immunological, genetic, and environmental changes, often complicating maternal and neonatal outcomes. Such changes can also impact the course of pre-existing skin disease during gestation. There are persistent gaps in clinical research, including the underrepresentation of pregnant patients, limited therapeutic options, and health disparities, continue to challenge optimal care. Recent advances in artificial intelligence offer promising opportunities for early diagnosis, enhanced risk assessment and drug safety, and expanded care access, particularly in underserved populations. Cultural, demographic, and genetic factors critically shape dermatologic presentations and outcomes, while inequities in data representation, algorithmic bias, and healthcare accessibility remain significant barriers. By integrating interdisciplinary innovations with culturally sensitive strategies, we propose a framework to optimize and globalize maternal-fetal dermatologic care.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conventional treatment of hidradenitis suppurativa: serving the "window of opportunity" concept. 化脓性汗腺炎的常规治疗：服务“机会之窗”概念。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-05-13 DOI: 10.1016/j.clindermatol.2025.05.015
T Tzellos
{"title":"Conventional treatment of hidradenitis suppurativa: serving the \"window of opportunity\" concept.","authors":"T Tzellos","doi":"10.1016/j.clindermatol.2025.05.015","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.05.015","url":null,"abstract":"<p><p>Hidradenitis suppurativa (HS) is a chronic, systemic, inflammatory skin disease characterized by inflammatory nodules, painful abscesses, and draining tunnels. It is associated with significant comorbidities, including inflammatory bowel disease, arthritis, pain, and a reduced quality of life. Unlike psoriasis or atopic dermatitis, it can progress from an inflammatory state to a nonreversible scaring component if not treated early enough and in an evidence-based manner. Until recently, adalimumab has been the only approved treatment for HS. Many conventional systemic treatments are currently used and have an appropriate role in HS therapy, provided they are used correctly in suitable patients. Unfortunately, many therapies, including antimicrobials, are used empirically, leading to continuous cycles of incorrect and inefficient treatment, disease progression, and reduced quality of life. Contributing to the problem is the delay in diagnosis which may be as long as seven years and insufficient or inappropriate intervention.. Capturing the \"window of opportunity\" is essential for a disease such as HS.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
WITHDRAWN: Cancer and Hidradenitis Suppurativa. 癌症和化脓性汗腺炎。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-05-13 DOI: 10.1016/j.clindermatol.2025.05.011
Philip R Cohen, Rena A Cohen-Kurzrock, Ryan R Riahi
{"title":"WITHDRAWN: Cancer and Hidradenitis Suppurativa.","authors":"Philip R Cohen, Rena A Cohen-Kurzrock, Ryan R Riahi","doi":"10.1016/j.clindermatol.2025.05.011","DOIUrl":"10.1016/j.clindermatol.2025.05.011","url":null,"abstract":"<p><p>The Publisher regrets that this article is an accidental duplication of an article that has already been published, http://dx.doi.org/10.1016/j.clindermatol.2025.05.011. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at https://www.elsevier.com/about/policies-and-standards/article-withdrawal.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biologic therapies and small molecules in the treatment of hidradenitis suppurativa. 生物疗法及小分子治疗化脓性汗腺炎。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-05-13 DOI: 10.1016/j.clindermatol.2025.05.004
Deša Tešanović Perković, Branka Marinović, Mara Tešanović, Zrinka Bukvić Mokos
{"title":"Biologic therapies and small molecules in the treatment of hidradenitis suppurativa.","authors":"Deša Tešanović Perković, Branka Marinović, Mara Tešanović, Zrinka Bukvić Mokos","doi":"10.1016/j.clindermatol.2025.05.004","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.05.004","url":null,"abstract":"<p><p>Hidradenitis suppurativa (HS) is a debilitating chronic skin condition challenging to manage. Treatment options range from topical and systemic medications to various surgical procedures. With the expanding knowledge of cytokine signaling pathways, systemic treatment for hidradenitis suppurativa is entering an exciting phase, offering new opportunities to address imbalanced immune responses. The primary categories of treatment include biologics and small molecules. Currently, the only three approved biologics for HS are the anti-TNF-α antibody adalimumab, the anti-IL-17A secukinumab and the anti-IL-17A/17F, bimekizumab. While studies indicate moderate effectiveness of all three drugs, achieving adequate disease control remains challenging for many patients. Research in the field of HS is rapidly evolving, with a wide range of treatments being developed that leverage various mechanisms of action. Drugs targeting the IL-17 and Janus kinase/signal transducer and activator of transcription (JAK/STAT) pathways show promise in ongoing and completed phase 3 studies, offering the potential for more comprehensive treatment responses.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethical Implications of Multi-Counting Similar Research for Dermatology Residency Applications. 多计数相似研究对皮肤科住院医师申请的伦理意义。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-05-13 DOI: 10.1016/j.clindermatol.2025.05.012
Aarushi K Parikh, Shari R Lipner
{"title":"Ethical Implications of Multi-Counting Similar Research for Dermatology Residency Applications.","authors":"Aarushi K Parikh, Shari R Lipner","doi":"10.1016/j.clindermatol.2025.05.012","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.05.012","url":null,"abstract":"<p><p>Increasing pressure on medical students to enhance their dermatology residency applications through research has led to the practice of multi-presenting the same work across multiple platforms, such as posters, oral presentations, and manuscripts. While this strategy can enhance visibility and recognition, it raises ethical concerns related to justice, fairness, honesty, integrity, authenticity, and transparency. This commentary examines the risks of misrepresenting research novelty, inflating academic records, and prioritizing quantity over quality in the dermatology residency selection process. Additionally, we discuss how multi-presenting may disadvantage medical students who produce high-quality work but refrain from such practices. To address these issues, we propose solutions for residency committees to better ensure the authenticity of applicants' academic achievements.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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