Clinics in dermatology最新文献

The impact of social media on patient behavior in aesthetic treatments: Decreased influence on patients at a reference center for aesthetic ultrasonography. 社交媒体对美容治疗中患者行为的影响：在美容超声检查参考中心对患者的影响降低。

IF 2.2 4区医学

Clinics in dermatology Pub Date : 2025-10-16 DOI: 10.1016/j.clindermatol.2025.10.005

Claudia Gonzalez, Juan Luis Martinez-Gonzalez, George Kroumpouzos

{"title":"The impact of social media on patient behavior in aesthetic treatments: Decreased influence on patients at a reference center for aesthetic ultrasonography.","authors":"Claudia Gonzalez, Juan Luis Martinez-Gonzalez, George Kroumpouzos","doi":"10.1016/j.clindermatol.2025.10.005","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.10.005","url":null,"abstract":"Social media (SM) has a significant impact on the public awareness of dermatologic conditions, as well as the perception of beauty and aesthetic pursuits of patients; however, they increase the risk of self-diagnosis and misinterpretation of clinical conditions as aesthetic ones. We discuss the risks of self-diagnosis, including delays in proper diagnosis or complications in treatment due to not seeking specific dermatologic assessment promptly, with tools such as high-resolution ultrasound. We specifically examined how SM influences patient behavior in aesthetic medicine by focusing on a group of patients seeking high-resolution ultrasound for diagnostic or aesthetic reasons at a specialized center for aesthetic ultrasonography. A total of 140 respondents (115 women, or 82.14%) completed a survey assessing their behaviors and attitudes related to SM. Among these, 37 respondents (26.4%) sought ultrasonography for aesthetic-related reasons. Interestingly, 66.43% of the participants reported having minimal or no influence from SM in their decision to undergo an aesthetic procedure, whereas only 19.29% felt moderately or highly influenced by SM. These findings suggest that our group of patients experienced less influence from SM compared with studies conducted on the general population. This difference may be attributed to the fact that most participants were referred by a dermatologist or surgeon, thus their access to dermatologic information was directly influenced by these professionals. Dermatologists should actively counter misinformation in clinical settings by ensuring clear communication to reduce patient misconceptions and educate them about the limitations of SM.","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical and Ethical Considerations in Nanotechnology-Based Dermatologic Care. 基于纳米技术的皮肤护理的临床和伦理考虑。

IF 2.2 4区医学

Clinics in dermatology Pub Date : 2025-10-16 DOI: 10.1016/j.clindermatol.2025.10.004

Isabella J Tan, Tarek Zieneldien, Sophia Ma, Jane M Grant-Kels

{"title":"Clinical and Ethical Considerations in Nanotechnology-Based Dermatologic Care.","authors":"Isabella J Tan, Tarek Zieneldien, Sophia Ma, Jane M Grant-Kels","doi":"10.1016/j.clindermatol.2025.10.004","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.10.004","url":null,"abstract":"Nanodermatology is the application of nanotechnology specifically to dermatology. We discuss the pros and cons of translating these innovations into routine dermatology practice, as well as the unique safety challenges, regulatory issues, and ethical and equity concerns surrounding nanodermatology. Unlike other emerging technologies, nanodermatology involves transcutaneous exposure to engineered nanoparticles that may penetrate beyond the epidermis, persist in tissues, and accumulate systemically. These characteristics create distinct safety and ethical challenges, including invisible patient exposure, uncertain long-term toxicologic effects, and unequal regulatory oversight across countries. The specific ethical issues involve nonmaleficence, informed consent, privacy, autonomy, and justice. Nanotechnology is emerging as a pivotal frontier in dermatology, with applications ranging from targeted drug delivery to nanoscale diagnostic sensors and advanced cosmetic formulations.1 Examples include nanoparticle-based topical formulations that increase delivery of immunomodulators into psoriatic plaques, micelle carriers for enhanced stratum corneum penetration of tacrolimus, and nanosensors capable of detecting inflammatory biomarkers in real-time.2 Recent studies emphasize nanodermatology, the application of nanotechnology specifically to dermatology as a potential solution for persistent challenges such as improving therapeutic efficacy, reducing systemic toxicity, and enabling precision dermatologic interventions.3 Translating these innovations into routine practice raises critical ethical, safety, and equity concerns.","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145318261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potpourri V: Dermatology at the Crossroads of Science, Society, and History. 百花香5：皮肤病学在科学，社会和历史的十字路口。

IF 2.2 4区医学

Clinics in dermatology Pub Date : 2025-10-09 DOI: 10.1016/j.clindermatol.2025.09.019

Vesna Petronic-Rosic, Franco Rongioletti, Leonard J Hoenig

引用次数: 0

Comment on "Beyond beauty: Neurocosmetics, the skin-brain axis, and the future of emotionally intelligent skincare". 评论“超越美丽：神经化妆品、皮肤-大脑轴和情商护肤的未来”。

IF 2.2 4区医学

Clinics in dermatology Pub Date : 2025-10-08 DOI: 10.1016/j.clindermatol.2025.10.001

S Dhanya Dedeepya, Vaishali Goel, Nivedita Nikhil Desai

引用次数: 0

Skin Cancer and Human Immunodeficiency Virus. 皮肤癌和人类免疫缺陷病毒。

IF 2.2 4区医学

Clinics in dermatology Pub Date : 2025-10-07 DOI: 10.1016/j.clindermatol.2025.09.014

Cory Kosche, Martin Tw Chio, Sarah T Arron

{"title":"Skin Cancer and Human Immunodeficiency Virus.","authors":"Cory Kosche, Martin Tw Chio, Sarah T Arron","doi":"10.1016/j.clindermatol.2025.09.014","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.09.014","url":null,"abstract":"The risk of skin cancer in persons living with HIV (PLWH) is an evolving subject area shaped by the use of antiretroviral therapy. Keratinocyte carcinomas, including basal and squamous cell carcinoma, have a high incidence in the general population and in PLWH. PLWH may have a higher risk of squamous cell carcinoma compared to the general population. In addition, Merkel cell carcinoma and sebaceous carcinoma exhibit higher incidence rates in PLWH. Data on melanoma risk are varied. Risks of skin cancer may be influenced by vigilant surveillance, photosensitivity, and immune status. Screening for skin cancer is generally recommended, although national guidelines vary in specific recommendations. Treatments range from topical therapies to surgeries to immune checkpoint inhibitors, with Mohs micrographic surgery playing an important role. Data on immune checkpoint inhibitors suggest safe and efficacious use in PLWH, although larger trials are warranted. The dynamic interplay between HIV, antiretroviral use and immunosuppression, and the risk and treatment of skin cancer underscores the importance of rigorous research studies and screening and treatment guidelines specific to this population.","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145257426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diseases named after fictional characters and celebrities. 以虚构人物和名人命名的疾病。

IF 2.2 4区医学

Clinics in dermatology Pub Date : 2025-10-07 DOI: 10.1016/j.clindermatol.2025.10.002

Uwe Wollina, Leonard J Hoenig, Lawrence Charles Parish

引用次数: 0

Primary cutaneous mucinoses in connective tissue diseases as a diagnostic and prognostic challenge. 结缔组织疾病的原发性皮肤粘液病作为诊断和预后的挑战。

IF 2.2 4区医学

Clinics in dermatology Pub Date : 2025-10-03 DOI: 10.1016/j.clindermatol.2025.09.028

Giorgio Stabile, Nazario Pesce, Giorgia Di Marco, Antonio Podo Brunetti, Gianmarco Diego Bigotto, Stefania Guida, Franco Rongioletti

引用次数: 0

Chancroid. Chancroid。

IF 2.2 4区医学

Clinics in dermatology Pub Date : 2025-10-03 DOI: 10.1016/j.clindermatol.2025.09.017

David A Lewis

引用次数: 0

Tadeusz Stepniewski: Polish dermatologist and "Righteous Among the Nations". Tadeusz stepeniewski：波兰皮肤科医生和“正义的国家”。

IF 2.2 4区医学

Clinics in dermatology Pub Date : 2025-10-03 DOI: 10.1016/j.clindermatol.2025.09.023

Sophie Walter

{"title":"Tadeusz Stepniewski: Polish dermatologist and \"Righteous Among the Nations\".","authors":"Sophie Walter","doi":"10.1016/j.clindermatol.2025.09.023","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.09.023","url":null,"abstract":"The life and career of Tadeusz Stepniewski (1905-1987), a Polish dermatologist awarded the title \"Righteous Among the Nations\" for his bravery saving Jews during the Holocaust, collates information about other dermatologists who have also received the title, and reflects on the place of virtue in the profession. Various sources were used to provide information about Stepniewski, including copies of materials held by the Archives Department of Yad Vashem, Israel's Holocaust memorial authority. At the outbreak of World War II, Stepniewski had a private dermatology practice in central Warsaw and was affiliated with the Skin and Venereal Diseases Clinic at the University of Warsaw. During the German occupation, he assisted Jews by helping them escape from the Warsaw ghetto, hiding them in various locations, providing dermatologic care and other medical treatments, contributing to an underground medical publication, and giving financial aid. Stepniewski is one of seven dermatologists who have received the Righteous Among the Nations title. Their heroic deeds bring to the fore the role of virtue in all aspects of the lives of dermatologists and other medical professionals.","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lymphocytic and Granulomatous Cutaneous Small Vessel Vasculitis Following PARP Inhibitor Therapy. PARP抑制剂治疗后淋巴细胞性和肉芽肿性皮肤小血管炎。

IF 2.2 4区医学

Clinics in dermatology Pub Date : 2025-10-03 DOI: 10.1016/j.clindermatol.2025.09.021

Carla Stephan, Cynthia Magro

{"title":"Lymphocytic and Granulomatous Cutaneous Small Vessel Vasculitis Following PARP Inhibitor Therapy.","authors":"Carla Stephan, Cynthia Magro","doi":"10.1016/j.clindermatol.2025.09.021","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.09.021","url":null,"abstract":"Olaparib is a poly adenosine diphosphate-ribose polymerase (PARP) inhibitor that is used in the treatment of advanced ovarian cancer. PARP inhibitors result in the accumulation of single-strand DNA breaks that are toxic to tumor cells. PARP inhibition with a concomitant BRCA mutation results in what is known as synthetic lethality to the tumor cells. Cutaneous adverse effects have been reported with PARP inhibition, namely pruritus, photosensitivity reactions, edema, vasculitis and panniculitis. We present a case of a 36-year-old female who developed a rash on the bilateral lower extremities one month after starting olaparib for advanced ovarian carcinoma. A punch biopsy taken from the rash was consistent with a lymphocytic and granulomatous small vessel vasculitis with a component of lobular panniculitis. The exact pathogenic mechanism of vasculitis and panniculitis in the setting of a PARP inhibitor is unclear. Given the multiple functions of PARP at the cellular level, it is not surprising that the inhibition of this superfamily may result in adverse effects. In particular, the inhibition of PARP has been shown to alter the inflammatory milieu from a Th2 predominance to a Th1 predominance. This shift in polarization may play a role in the development of vasculitis and panniculitis in such patients.","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0