Clinics in dermatology最新文献

Picosecond Laser Therapy for Traumatic and Surgical Scars: a Systematic Review. 皮秒激光治疗创伤性和外科疤痕：系统综述。

IF 3.5 4区医学

Clinics in dermatology Pub Date : 2026-10-17 DOI: 10.1016/j.clindermatol.2026.10.008

Jade Oliveira, Nathalia Sernizon Guimarães, Analupe Webber, Keila Seabra Teles Ferreira, George Kroumpouzos, Gisele Viana de Oliveira

{"title":"Picosecond Laser Therapy for Traumatic and Surgical Scars: a Systematic Review.","authors":"Jade Oliveira, Nathalia Sernizon Guimarães, Analupe Webber, Keila Seabra Teles Ferreira, George Kroumpouzos, Gisele Viana de Oliveira","doi":"10.1016/j.clindermatol.2026.10.008","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2026.10.008","url":null,"abstract":"Background: Traumatic and surgical scars may cause functional impairment, cosmetic concerns, and reduced quality of life. This review evaluated the effectiveness and safety of picosecond laser therapy for traumatic and surgical scars.Methods: we conducted a systematic review in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 statement. PubMed, Scopus, Web of Science, Embase, Cochrane Library, MEDLINE, LILACS, and VERTINDEX were searched from inception through August 2025 without language or date restrictions; database alerts were monitored through December 2025. Clinical studies evaluating picosecond laser therapy for non-acne traumatic or surgical scars were included. Risk of bias in randomized trials was assessed using RoB 2.Results: 13 studies (446 patients, 475 scars), including five randomized controlled studies, met eligibility criteria. Most studies showed improvement in validated scar scales, global aesthetic assessments, and objective measures. Controlled trials generally favored picosecond laser therapy over untreated controls and showed advantages over fractional carbon dioxide laser for selected outcomes, although superiority was not consistent across all domains. Four randomized studies were judged to have some concerns and one was at high overall risk of bias. Adverse events were predominantly mild and transient, with no serious or permanent events.Conclusions: current evidence supports picosecond laser therapy as a promising and generally well-tolerated option for traumatic and surgical scars. However, heterogeneity in scar characteristics, treatment protocols, and outcome measures.","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149215126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

AI-Powered Prescribing in Dermatology and Its Clinical Opportunities, Risks, and Ethical Considerations. 皮肤病学中的人工智能处方及其临床机会、风险和伦理考虑。

IF 3.5 4区医学

Clinics in dermatology Pub Date : 2026-10-15 DOI: 10.1016/j.clindermatol.2026.10.007

Mohamad Goldust, Jane M Grant-Kels

引用次数: 0

Beyond Legal Compliance: Ethical Obligations for Lactation Accommodations in Dermatology Residency. 超越法律合规：皮肤科住院医师哺乳住宿的道德义务。

IF 3.5 4区医学

Clinics in dermatology Pub Date : 2026-10-13 DOI: 10.1016/j.clindermatol.2026.10.006

Gabriella Resnick, Shari R Lipner

引用次数: 0

From Empiricism to Precision: Century of Paradigm Shifts in Medical Dermatology. 从经验主义到精确：医学皮肤病学范式转变的世纪。

IF 3.5 4区医学

Clinics in dermatology Pub Date : 2026-10-13 DOI: 10.1016/j.clindermatol.2026.10.005

Jacob Beer, Tanya Boghosian, Mohamad Goldust, Jane M Grant-Kels, Marina Landua

{"title":"From Empiricism to Precision: Century of Paradigm Shifts in Medical Dermatology.","authors":"Jacob Beer, Tanya Boghosian, Mohamad Goldust, Jane M Grant-Kels, Marina Landua","doi":"10.1016/j.clindermatol.2026.10.005","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2026.10.005","url":null,"abstract":"Over the past century, advances in scientific understanding and therapeutic development have fundamentally reshaped dermatology. Diseases once managed with empiric, toxic, or largely ineffective treatments can now be approached with therapies that target specific pathways, achieve sustained disease control, and, in some cases, alter prognosis. Herein, we reviewed landmark therapeutic advances across infectious, inflammatory, autoimmune, vascular, and oncologic dermatology, focusing on interventions that changed the standard of care or substantially improved patient outcomes. Transformative advances include penicillin for syphilis, isotretinoin for severe acne, biologics for psoriasis, corticosteroids and rituximab for pemphigus vulgaris, targeted biologic and Janus kinase inhibitors for inflammatory and autoimmune diseases, beta-blockers for infantile hemangiomas, immunotherapy and targeted therapy for cutaneous malignancies, and Hedgehog pathway inhibitors for advanced basal cell carcinoma. Collectively, these breakthroughs expanded what treatment could achieve, from curing previously chronic infection and controlling severe inflammatory disease to restoring hair or pigmentation and prolonging survival in advanced malignancy. Progress arose through both sustained research into disease biology and unexpected clinical observations that opened new therapeutic possibilities. These landmark therapeutic breakthroughs trace dermatology's evolution from empiric treatment toward increasingly precise, mechanism-based care. This history illustrates how scientific discovery and clinical observation can redefine the management and prognosis of dermatologic disease.","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Metabolic-Dermatologic Axis: GLP-1/GIP Agonists as Emerging Immunometabolic Therapies for Obesity-Associated Skin Disease. 代谢-皮肤病学轴：GLP-1/GIP激动剂作为肥胖相关皮肤病的新兴免疫代谢疗法

IF 3.5 4区医学

Clinics in dermatology Pub Date : 2026-10-12 DOI: 10.1016/j.clindermatol.2026.09.040

Fabio Biondi, Giulia Veneziano, Stefania Guida, Franco Rongioletti

引用次数: 0

Cutaneous Effects and Aesthetic Management of Glucagon-like Peptide-1 Receptor Agonists: A Narrative Review. 胰高血糖素样肽-1受体激动剂的皮肤效应和美学管理：叙述综述。

IF 3.5 4区医学

Clinics in dermatology Pub Date : 2026-10-12 DOI: 10.1016/j.clindermatol.2026.09.041

Benjamin D Hu, Courtney A Chau, Sabrina Ghalili, Kristina Navrazhina, Emma Guttman-Yassky, Helen He

{"title":"Cutaneous Effects and Aesthetic Management of Glucagon-like Peptide-1 Receptor Agonists: A Narrative Review.","authors":"Benjamin D Hu, Courtney A Chau, Sabrina Ghalili, Kristina Navrazhina, Emma Guttman-Yassky, Helen He","doi":"10.1016/j.clindermatol.2026.09.041","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2026.09.041","url":null,"abstract":"Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are among the most widely prescribed medications in the United States, with expanding indications beyond type-2 diabetes mellitus to include obesity, cardiovascular risk reduction, and metabolic dysfunction-associated steatohepatitis. As their utilization increases, the dermatologic effects of these agents become increasingly relevant to clinical practice. This narrative review examines the cutaneous effects of GLP-1RAs across six domains: facial volume loss and accelerated skin aging, changes in hair density, wound healing, striae distensae and body skin laxity, cutaneous adverse events, and emerging therapeutic benefits in inflammatory skin disease. Herein, we review proposed mechanisms and evidence-based management strategies for each domain, including biostimulatory fillers, energy-based devices, nutritional optimization, and pharmacologic interventions. Prospective, large-scale clinical studies are needed to clarify mechanisms of GLP-1RA modulation in skin and to guide management of these AEs as next-generation agents enter clinical practice.","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

"Ozempic Face" and Facial Aging. “臭氧脸”和面部老化。

IF 3.5 4区医学

Clinics in dermatology Pub Date : 2026-10-10 DOI: 10.1016/j.clindermatol.2026.10.004

Sam Fathizadeh, Angelina S Hwang, Elika Hoss

引用次数: 0

Military shaving waivers for pseudofolliculitis barbae: Ethical considerations for dermatologists. 假性毛囊炎的军事剃须豁免：皮肤科医生的伦理考虑。

IF 3.5 4区医学

Clinics in dermatology Pub Date : 2026-10-09 DOI: 10.1016/j.clindermatol.2026.10.003

Geat Ramush, Jinho Kim, Shari R Lipner

{"title":"Military shaving waivers for pseudofolliculitis barbae: Ethical considerations for dermatologists.","authors":"Geat Ramush, Jinho Kim, Shari R Lipner","doi":"10.1016/j.clindermatol.2026.10.003","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2026.10.003","url":null,"abstract":"Pseudofolliculitis barbae (PFB) is a chronic inflammatory disorder triggered by shaving and disproportionately affects individuals of African descent. For service members, medically appropriate management may conflict with military grooming standards requiring a clean-shaven appearance. Recent policy changes have placed greater restrictions on shaving waivers and may create career consequences for service members who continue to require accommodations despite treatment. These policies raise ethical concerns involving justice, beneficence, nonmaleficence, and autonomy. Military safety requirements related to protective equipment must be balanced against the clinical needs of patients with PFB. Laser hair removal may provide meaningful benefit but can recur, permanently alter facial hair growth, and carry additional risks depending on skin type, device selection, and treatment setting. Dermatologists should provide accurate medical assessments, support medically necessary accommodations, and use shared decision-making so that treatment remains guided by clinical need and patient preference rather than institutional pressure.","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149147888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Military shaving waivers for pseudofolliculitis barbae: Ethical considerations for dermatologists. 假性毛囊炎的军事剃须豁免：皮肤科医生的伦理考虑。

IF 3.5 4区医学

Clinics in dermatology Pub Date : 2026-10-08 DOI: 10.1016/j.clindermatol.2026.10.002

Geat Ramush, Jinho Kim, Shari R Lipner

{"title":"Military shaving waivers for pseudofolliculitis barbae: Ethical considerations for dermatologists.","authors":"Geat Ramush, Jinho Kim, Shari R Lipner","doi":"10.1016/j.clindermatol.2026.10.002","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2026.10.002","url":null,"abstract":"Pseudofolliculitis barbae (PFB) is a chronic inflammatory disorder triggered by shaving and disproportionately affects individuals of African descent. For service members, medically appropriate management may conflict with military grooming standards requiring a clean-shaven appearance. Recent policy changes have tightened restrictions on shaving waivers and may create career consequences for service members who still require accommodations despite treatment. These policies raise ethical concerns involving justice, beneficence, nonmaleficence, and autonomy. Military safety requirements related to protective equipment must be balanced against the clinical needs of patients with PFB. Laser hair removal may provide meaningful benefit but can recur, permanently alter facial hair growth, and carry additional risks depending on skin type, device selection, and treatment setting. Dermatologists should provide accurate medical assessments, support medically necessary accommodations, and use shared decision-making so that treatment remains guided by clinical need and patient preference rather than institutional pressure.","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149135174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Ethical and Practical Issues of Market Exclusivity for Naturally Derived Dermatologic Medications: The Case of Cantharidin. 自然衍生皮肤药物市场独占性的伦理和实践问题：斑蝥素的案例。

IF 3.5 4区医学

Clinics in dermatology Pub Date : 2026-10-06 DOI: 10.1016/j.clindermatol.2026.10.001

Danielle M Khalilzadeh, Timothy Klufas, Albert E Zhou, Jane M Grant-Kels

引用次数: 0