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Clinics in dermatology最新文献

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Life-threatening dermatoses.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2024-12-14 DOI: 10.1016/j.clindermatol.2024.12.008
Caroline A Nelson, Jonathan S Leventhal
{"title":"Life-threatening dermatoses.","authors":"Caroline A Nelson, Jonathan S Leventhal","doi":"10.1016/j.clindermatol.2024.12.008","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2024.12.008","url":null,"abstract":"<p><p>While rare, life-threatening dermatoses encompass various inflammatory, infectious, vasculitic/vasculopathy, paraneoplastic, and neoplastic skin diseases. Complications include skin barrier dysfunction, secondary infection, and internal organ involvement. Skin signs may serve as a critical window into systemic disease. Life-threatening dermatoses are typically associated with \"red flag\" clinical signs or symptoms, which inform the dermatologist about the severity of the disease and mandate a thorough history, review of systems, and physical examination, as well as laboratory evaluation. This contribution highlights severe cutaneous adverse reactions, infections, vasculitides and vasculopathies, and paraneoplastic eruptions. Dermatologists should recognize life-threatening dermatoses and have a framework for rapid diagnosis and management.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical Education in Dermatology.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2024-12-14 DOI: 10.1016/j.clindermatol.2024.12.010
Suguru Imaeda, Mary M Tomayko
{"title":"Medical Education in Dermatology.","authors":"Suguru Imaeda, Mary M Tomayko","doi":"10.1016/j.clindermatol.2024.12.010","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2024.12.010","url":null,"abstract":"<p><p>Dermatology faculty are responsible for the undergraduate education of all medical students, most of whom will not become dermatologists but will, nonetheless, encounter skin disease throughout their careers, and for dermatology residents' intensive, specialized graduate education. Over the past 75 years, dermatology faculty have grappled with determining what comprises the fundamental curriculum and how to teach it effectively, grumbled about time limitations, and eloquently debated the fundamental role of dermatology in general medical education. While dermatology trainee education continues to evolve, fundamentals still focus on observational skills developed through clinical and nonclinical experiences. We highlight major trends and turning points in undergraduate and graduate dermatology education that have occurred during the career of Dr. Irwin M. Braverman, many of which Dr. Braverman himself influenced, and reflect on the current state of dermatology education at our institution.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142834294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic and Molecular Drivers of Scleroderma Pathogenesis.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2024-12-13 DOI: 10.1016/j.clindermatol.2024.12.007
Ian D Odell
{"title":"Genetic and Molecular Drivers of Scleroderma Pathogenesis.","authors":"Ian D Odell","doi":"10.1016/j.clindermatol.2024.12.007","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2024.12.007","url":null,"abstract":"<p><p>Scleroderma is a heterogeneous disease with various clinical findings involving immune dysregulation, vasculopathy, and fibrosis. Biologic and genetic studies over recent decades have elucidated molecular mechanisms of scleroderma pathogenesis. Genetic association studies have identified interferon and other immune regulatory genes as strongly linked to scleroderma risk, highlighting the immune system as a fundamental determinant of disease. Human and murine biologic studies have identified growth factor signaling as a central feature linking tissue damage to the clinical phenotype. Growth factors activated in vascular endothelial cells overlap with those of other diseases having vascular abnormalities, such as hereditary hemorrhagic telangiectasia. Activated growth factor receptors in fibroblasts drive excessive collagen expression in the skin and lungs. Because growth factor signaling is overactivated in multiple malignancies, biologic insights and therapeutic approaches may be translated from oncology to understand scleroderma better. Enhanced understanding of the molecular drivers of scleroderma pathogenesis has given greater insight into patient phenotypes and new therapeutic approaches, including those that target immune and growth factor signaling.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Constant Desbordes Painting of Jean-Louis Alibert Administering the Smallpox Vaccine ("La Vaccine"): An Historic Vaccination or Artistic Imagination? Constant Desbordes 画作《让-路易-阿利伯特注射天花疫苗》（"La Vaccine"）：历史上的疫苗接种还是艺术想象？
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2024-12-13 DOI: 10.1016/j.clindermatol.2024.12.003
Leonard J Hoenig, Uwe Wollina, Gerard Tilles, Daniel Wallach, Lawrence Charles Parish
{"title":"Constant Desbordes Painting of Jean-Louis Alibert Administering the Smallpox Vaccine (\"La Vaccine\"): An Historic Vaccination or Artistic Imagination?","authors":"Leonard J Hoenig, Uwe Wollina, Gerard Tilles, Daniel Wallach, Lawrence Charles Parish","doi":"10.1016/j.clindermatol.2024.12.003","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2024.12.003","url":null,"abstract":"<p><p>In 1822, France's Ministry of the Interior, concerned about dropping vaccination rates among the population, commissioned the French artist Constant Joseph Desbordes (1761-1828) to create an artwork that would educate the public about the benefits of the smallpox vaccine. The Painting that resulted is entitled: \"La Vaccine\" (\"The Cowpox Inoculation\") and a copy of it is entitled \"La Vaccine au Chateau de Liancourt\" (\"Performing the Vaccination against Smallpox in the Chateau of Liancourt\"). The highlight of the painting is its central figure, one of France's most distinguished physicians, Jean-Louis Alibert (1768-1837) performing, in dramatic fashion, the arm to arm method of smallpox vaccination that was common at that time. The painting was highly praised for bringing together, on opposite sides of the painting, persons from lower and upper socioeconomic classes, with Alibert serving as a bridge between them. The setting for the painting is a chateau and there is no evidence that a smallpox vaccination ever took place there. Thus, this painting is not a record of a specific, real-life vaccination but a celebration of vaccination itself, in an idealized artistic representation. The painting honors Alibert, a strong advocate of vaccination and demonstrates how art can impact patient education.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin Cancer and Sunscreen.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2024-12-09 DOI: 10.1016/j.clindermatol.2024.12.001
Jahleel Perrin
{"title":"Skin Cancer and Sunscreen.","authors":"Jahleel Perrin","doi":"10.1016/j.clindermatol.2024.12.001","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2024.12.001","url":null,"abstract":"","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142812249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermatology office visit out-of-pocket costs and copays: A Medicare Physician Office Visit Costs database study, 2020 - 2024: Dermatology office visit OOP costs and copays.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2024-12-07 DOI: 10.1016/j.clindermatol.2024.12.002
Kaushik P Venkatesh, Gabriel Brito, Vinod E Nambudiri
{"title":"Dermatology office visit out-of-pocket costs and copays: A Medicare Physician Office Visit Costs database study, 2020 - 2024: Dermatology office visit OOP costs and copays.","authors":"Kaushik P Venkatesh, Gabriel Brito, Vinod E Nambudiri","doi":"10.1016/j.clindermatol.2024.12.002","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2024.12.002","url":null,"abstract":"","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impersonating Expertise: The Ethics of Misleading Dermatology Advertising.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2024-12-03 DOI: 10.1016/j.clindermatol.2024.11.005
Akash Rau, Andrew Z Li, Julia Giordano, Jane M Grant-Kels, Zelma C Chiesa Fuxench
{"title":"Impersonating Expertise: The Ethics of Misleading Dermatology Advertising.","authors":"Akash Rau, Andrew Z Li, Julia Giordano, Jane M Grant-Kels, Zelma C Chiesa Fuxench","doi":"10.1016/j.clindermatol.2024.11.005","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2024.11.005","url":null,"abstract":"<p><p>The proliferation of medical spas has led to an increase in misleading advertising practices, particularly relating to the qualifications of practitioners and the risks of cosmetic procedures. Aestheticians manage many spas without having the extensive and rigorous training that board-certified dermatologists undergo. By advertising physician oversight when there is none and promoting procedures as minimally invasive, these facilities create a false sense of security for patients. Procedures such as laser therapies and injectables require specialized expertise to avoid and, if necessary, treat potentially dangerous complications. The ethics of misleading advertising in dermatology must be considered due to its impact on patient decision-making (autonomy), safety (beneficence), and confidence regarding the medical profession.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comprehensive Bibliometric Analysis of Prurigo Nodularis Literature (1951-2024): Key Contributors, Trends, and Thematic Evolution.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2024-11-26 DOI: 10.1016/j.clindermatol.2024.11.004
Siddig Ibrahim Abdelwahab, Abdullah Farasani, Hassan Ahmad Alfaifi, Ahmed S Alamer, Tawfeeq Altherwi, Saeed Alshahrani, Ahmad Assiri, Waseem Hassan
{"title":"A Comprehensive Bibliometric Analysis of Prurigo Nodularis Literature (1951-2024): Key Contributors, Trends, and Thematic Evolution.","authors":"Siddig Ibrahim Abdelwahab, Abdullah Farasani, Hassan Ahmad Alfaifi, Ahmed S Alamer, Tawfeeq Altherwi, Saeed Alshahrani, Ahmad Assiri, Waseem Hassan","doi":"10.1016/j.clindermatol.2024.11.004","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2024.11.004","url":null,"abstract":"<p><p>This study provides a comprehensive bibliometric analysis of Prurigo Nodularis (PN) literature, identifying influential studies, key contributors, and emerging trends to understand the evolution of research and guide future investigations. A total of 499 papers published between 1951 and October 2024, containing the term Prurigo Nodularis in their abstracts, were analyzed. Keyword analysis was conducted to determine the main themes across these publications. Additionally, the top 100 most cited PN papers from 1979 to 2023 were examined, involving 51 journals and sources. Metrics such as mean total citations per article (MeanTCperArt) and mean total citations per year (MeanTCperYear) were calculated for these top 100 papers. The analysis of the top 100 most cited papers revealed contributions from 453 authors. The number of publications, citations, h-index, g-index, m-index, HG composite, and Q2 index were calculated for each. We have illustrated the dynamics of top authors, universities, and countries, as well as their respective collaboration networks. The thematic evolution of PN research was assessed using co-word analysis, followed by a systematic discussion of the findings. This bibliometric analysis provides a comprehensive overview of the key contributors and research trends in PN literature, offering valuable insights for guiding future investigations.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Church Spire Sign. 教堂尖顶标志。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2024-11-23 DOI: 10.1016/j.clindermatol.2024.11.003
Uwe Wollina, Leonard J Hoenig, Sophie Walter, Lawrence Charles Parish
{"title":"The Church Spire Sign.","authors":"Uwe Wollina, Leonard J Hoenig, Sophie Walter, Lawrence Charles Parish","doi":"10.1016/j.clindermatol.2024.11.003","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2024.11.003","url":null,"abstract":"<p><p>We are pleased to introduce in this issue of Clinics in Dermatology a new section entitled \"Art in Dermatology\", which explores the interface between the visual arts and dermatology. This contribution focuses on the architectural structure known as a church spire that sits atop a church tower and which has lent its name to a dermatologic sign. Key phrases play an important role in clinical dermatology and dermatopathology. The \"church spire sign\" is a descriptive term used to describe epidermal changes of hyperkeratosis, acanthosis, and elongated projections (papillomatosis) in various cutaneous disorders. Zvonimir Zambal (1922-1993) coined the term \"church spire sign\" in a contribution he published in 1965 with Hans Gotz (1915-1997). The term was adopted promptly by the dermatology community and was applied in 1966 by Emery Kocsard (1912-2005) and his colleague Franjo Ofner (1913-1973) in stucco keratosis. We describe the beautiful church spires of the Bamberg Cathedral located in Bamberg, Germany and compare its architectural appearance with the dermatopathology features seen in the church spire sign.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A collaborative effort between dermatologists, obstetrician-gynecologists, urologists, and family medicine physicians to rethink routine genitourinary examinations: The overlooked importance of screening for genital squamous cell carcinoma in situ. 皮肤科医生、妇产科医生、泌尿科医生和家庭医生通力合作，重新思考泌尿生殖系统常规检查：被忽视的生殖器鳞状细胞原位癌筛查的重要性。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2024-11-20 DOI: 10.1016/j.clindermatol.2024.11.001
Kritin K Verma, Sabrina C Camacho, Daniel P Friedmann, Michelle B Tarbox, Theodore Rosen
{"title":"A collaborative effort between dermatologists, obstetrician-gynecologists, urologists, and family medicine physicians to rethink routine genitourinary examinations: The overlooked importance of screening for genital squamous cell carcinoma in situ.","authors":"Kritin K Verma, Sabrina C Camacho, Daniel P Friedmann, Michelle B Tarbox, Theodore Rosen","doi":"10.1016/j.clindermatol.2024.11.001","DOIUrl":"10.1016/j.clindermatol.2024.11.001","url":null,"abstract":"","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142692599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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