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Evolving Evidence in the Neural Sensitization of Prurigo Nodularis.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-03-15 DOI: 10.1016/j.clindermatol.2025.03.008
Sarah G Brooks, Gil Yosipovitch
{"title":"Evolving Evidence in the Neural Sensitization of Prurigo Nodularis.","authors":"Sarah G Brooks, Gil Yosipovitch","doi":"10.1016/j.clindermatol.2025.03.008","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.03.008","url":null,"abstract":"","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Xerosis cutis and Wounded Skin in Modern Art: Two Works by Alberto Burri. 现代艺术中的皮肤干燥症和受伤的皮肤：阿尔贝托-布里的两幅作品
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-03-14 DOI: 10.1016/j.clindermatol.2025.03.001
Uwe Wollina, Leonhard J Hoenig, Lawrence Charles Parish
{"title":"Xerosis cutis and Wounded Skin in Modern Art: Two Works by Alberto Burri.","authors":"Uwe Wollina, Leonhard J Hoenig, Lawrence Charles Parish","doi":"10.1016/j.clindermatol.2025.03.001","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.03.001","url":null,"abstract":"<p><p>The human skin has been a subject of medicine and art. The interest in the interaction of skin and the inner body had increased after the establishment of anatomy as a science long before dermatology was acknowledged as a medical discipline. In painting the body surface, the Inkarnat (flesh tone) represents a mixture of the superficial epidermis and dermis, plus the deeper musculature and vasculature, each contributing to the skin color. In the fine arts of the Renaissance, skin is understood as primarily a layer of material. The human skin can express feelings, emotions, and various states of mind. We analyze two works of the Italian artist Alberto Burri (1915-1995), who painted in the post-war period. He opens a window into human existence with his materials while showing both the tragedies and wounds.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnosis and management of prurigo nodularis in skin of color patients.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-03-14 DOI: 10.1016/j.clindermatol.2025.03.004
Akash Rau, Danyelle Dawes
{"title":"Diagnosis and management of prurigo nodularis in skin of color patients.","authors":"Akash Rau, Danyelle Dawes","doi":"10.1016/j.clindermatol.2025.03.004","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.03.004","url":null,"abstract":"<p><p>Prurigo nodularis is a chronic, intensely pruritic eruption that results in excoriated papules mostly on the extensor surfaces of the arms and legs. Previous studies have indicated the condition disproportionally affects those of African descent. While the etiology has not been fully elucidated, patients with prurigo nodularis have been found to have associated comorbidities such as hypertension, renal disease, and HIV infection. This review covers the principles of work-up and diagnosis of prurigo nodularis in skin of color patients as well as management considerations in this population.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional Magnetic Resonance Imaging in Prurigo Nodularis: A Systematic Review.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-03-14 DOI: 10.1016/j.clindermatol.2025.03.005
Xuanyu Zhao, Jannis M Mueller, Simon M Mueller
{"title":"Functional Magnetic Resonance Imaging in Prurigo Nodularis: A Systematic Review.","authors":"Xuanyu Zhao, Jannis M Mueller, Simon M Mueller","doi":"10.1016/j.clindermatol.2025.03.005","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.03.005","url":null,"abstract":"<p><p>Prurigo nodularis (PN) is a chronic pruritic inflammatory skin condition characterized by nodular skin lesions in a typical distribution pattern caused by various dermatological and/or non-dermatological conditions. In recent years, significant advances have been made in the understanding of the cutaneous pathophysiology of PN resulting in novel treatment options such as Interleukin-4, -13, -17, -31- or Januskinase inhibitors. However, many aspects of the neurophysiology are largely unknown, including the processing in the central structural and functional network involved in PN. Functional neuroimaging allows non-invasive assessment of brain function and structure. Due to its high spatial resolution and temporal precision, functional magnetic resonance imaging (fMRI) has proven to be a suitable method for exploring neural mechanisms and assessing pharmacological effects in dermatological research. In this systematic review, the current knowledge of fMRI in the context of PN and its centrally active treatment options is summarized.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New Definitions and Subtypes of Chronic Prurigo.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-03-14 DOI: 10.1016/j.clindermatol.2025.03.009
Lea Sophie Stahl, Sonja Ständer, Claudia Zeidler
{"title":"New Definitions and Subtypes of Chronic Prurigo.","authors":"Lea Sophie Stahl, Sonja Ständer, Claudia Zeidler","doi":"10.1016/j.clindermatol.2025.03.009","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.03.009","url":null,"abstract":"<p><p>Over the past few years, chronic prurigo, including prurigo nodularis, has become a focal point of considerable research attention, resulting in enhanced insights into this condition. For over two centuries, the term \"prurigo\" has been utilized in dermatology, often applied loosely to describe a range of pruritic, papulous conditions lacking clear diagnostic criteria. In 2017, the term \"chronic prurigo\" was introduced, delineating chronic prurigo including prurigo nodularis as a distinct disease entity characterized by chronic pruritus, a characteristic clinical history, and physical signs such as excoriations and the presence of pruriginous lesions. Pruriginous lesions exhibit diverse morphologies, encompassing papules (diameter < 1 cm), nodules (diameter > 1 cm), plaques, and umbilicated or linear lesions. Co-occurrence of multiple lesion types within an individual is frequently observed. The subtype and severity of chronic prurigo can be categorised on the basis of the type or number of pruriginous lesions.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utilization of preference signaling in dermatology residency applications during the 2023-2024 match cycle: A program leadership survey. 在 2023-2024 年配对周期内皮肤科住院医师申请中使用偏好信号：项目领导力调查。
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-02-26 DOI: 10.1016/j.clindermatol.2025.02.011
Timothy Klufas, Shannon Hanggodo, Albert E Zhou, Steven Brett Sloan, Gillian K Weston
{"title":"Utilization of preference signaling in dermatology residency applications during the 2023-2024 match cycle: A program leadership survey.","authors":"Timothy Klufas, Shannon Hanggodo, Albert E Zhou, Steven Brett Sloan, Gillian K Weston","doi":"10.1016/j.clindermatol.2025.02.011","DOIUrl":"10.1016/j.clindermatol.2025.02.011","url":null,"abstract":"<p><p>The National Resident Matching Program, also known as The Match,ital uses a Nobel Prize-winning algorithm to determine the residency placement for fourth-year medical students. Dermatology remains one of the most competitive specialties within The Match ital. A process of preference signaling was implemented to allow applicants to express interest in individual residency programs at the time of application. The impact, significance, and best use of these signals remain unclear. This study aimed to elucidate the utilization and perceived impact of the signaling schema as it pertains to the 2023-2024 Match in Dermatology. The survey results provide valuable insights into the influence and impressions of signaling from the perspective of dermatology residency program leadership. The results may inform the advising of future applicants and evolution of the signaling schema of The Match italprocess.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vitiligo and melanoma: Revisiting a historic relationship through a retrospective case-control investigation. 白癜风与黑色素瘤：通过回顾性病例对照调查重新审视历史关系
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-02-26 DOI: 10.1016/j.clindermatol.2025.02.012
Kritin K Verma, Hannah Chaudhury, Tristin Chaudhury, Hannah Seo, Katherine Holder, Josephine Chiu, Quyen Nguyen, Antoine Nguyen, Maitreyi Dhavala, Smriti Panchal, Sumoni Verma, Joshua Connor, Erica Kim, Aditi K Khareedhi, Selina Noe, Aditi Kumar, Daniel P Friedmann, Michelle B Tarbox
{"title":"Vitiligo and melanoma: Revisiting a historic relationship through a retrospective case-control investigation.","authors":"Kritin K Verma, Hannah Chaudhury, Tristin Chaudhury, Hannah Seo, Katherine Holder, Josephine Chiu, Quyen Nguyen, Antoine Nguyen, Maitreyi Dhavala, Smriti Panchal, Sumoni Verma, Joshua Connor, Erica Kim, Aditi K Khareedhi, Selina Noe, Aditi Kumar, Daniel P Friedmann, Michelle B Tarbox","doi":"10.1016/j.clindermatol.2025.02.012","DOIUrl":"10.1016/j.clindermatol.2025.02.012","url":null,"abstract":"","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum to "Persian contributions to dermatology" [Clin Dermatol 2024:42 515-516].
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-02-20 DOI: 10.1016/j.clindermatol.2025.01.007
Mohamad Goldust, Marina Landau, Jane M Grant-Kels
{"title":"Erratum to \"Persian contributions to dermatology\" [Clin Dermatol 2024:42 515-516].","authors":"Mohamad Goldust, Marina Landau, Jane M Grant-Kels","doi":"10.1016/j.clindermatol.2025.01.007","DOIUrl":"https://doi.org/10.1016/j.clindermatol.2025.01.007","url":null,"abstract":"","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143472404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ethics of reversible dermatologic care in transgender and gender-diverse adolescents under restrictive and ambiguous laws.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-02-20 DOI: 10.1016/j.clindermatol.2025.02.010
Priya Patel Housley, Sami K Saikaly, Neelesh Jain, Jane M Grant-Kels
{"title":"Ethics of reversible dermatologic care in transgender and gender-diverse adolescents under restrictive and ambiguous laws.","authors":"Priya Patel Housley, Sami K Saikaly, Neelesh Jain, Jane M Grant-Kels","doi":"10.1016/j.clindermatol.2025.02.010","DOIUrl":"10.1016/j.clindermatol.2025.02.010","url":null,"abstract":"<p><p>Gender dysphoria causes significant distress in transgender and gender-diverse (TGD) adolescents, often impacting their mental health. Evidence-based gender-affirming interventions, such as hormone therapy, have been shown to reduce this distress and lower suicide risk, and dermatological treatments may help alleviate gender dysphoria. However, recent state-specific legal restrictions and ambiguous laws in the United States (US) have created barriers for TGD adolescents from accessing these treatments; some states have passed new laws that restrict TGD youth access to surgical and even medical gender affirming services as hormone treatment. We explore dermatologists' challenges in providing care to TGD adolescents in legally ambiguous and restrictive states in the context of the core ethical principles of autonomy, beneficence, nonmaleficence, and justice. Using exemplary case studies, we discuss ethical dilemmas involving dermal fillers, laser hair removal, hair growth treatments, and acne management for TGD adolescents living in such states. We find that as such treatments are available in other geographic locations, available for cis-gender individuals and not necessarily permanent, there is a violation of the core principle of justice. Dermatologists should navigate these legal and ethical complexities to provide safe, compassionate care for TGD adolescents. Advocacy for clear state-specific guidelines, equitable access to care, and ongoing research are essential to support this vulnerable population.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The skincare craze among tweens: Ethical and dermatologic implications of social media beauty trends.
IF 2.3 4区 医学
Clinics in dermatology Pub Date : 2025-02-17 DOI: 10.1016/j.clindermatol.2025.02.009
Rachel Wetstone, Jane M Grant-Kels
{"title":"The skincare craze among tweens: Ethical and dermatologic implications of social media beauty trends.","authors":"Rachel Wetstone, Jane M Grant-Kels","doi":"10.1016/j.clindermatol.2025.02.009","DOIUrl":"10.1016/j.clindermatol.2025.02.009","url":null,"abstract":"<p><p>The rise of social media has significantly influenced how younger generations engage with skincare, exposing them to trends that may not be developmentally appropriate. Platforms such as TikTok have fueled the popularity of skincare among tweens, leading to increased use of products often unsuitable for their skin. This trend has raised ethical concerns about (1) transparency and informed consent, (2) premature and inappropriate beauty standards, and (3) financial exploitation. Dermatologists report an increase in the number of young patients experiencing adverse skin reactions due to inappropriate product use, although mental health professionals note growing anxiety related to beauty dysmorphia. The lack of regulation leaves young consumers vulnerable. Addressing this issue requires collaboration among parents, educators, dermatologists, and influencers to promote responsible skincare education and ethical marketing. Stricter oversight and informed guidance are essential to ensuring young consumers develop healthy, age-appropriate skincare habits.</p>","PeriodicalId":10358,"journal":{"name":"Clinics in dermatology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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