Clinical Gastroenterology and Hepatology最新文献_第3页

Needle Track Seeding after Trans-gastric EUS-guided Tissue Sampling: Maybe not as Rare as You Think. 经胃 EUS 引导组织取样后的针道播散：也许并不像您想象的那么罕见

IF 11.6 1区医学

Clinical Gastroenterology and Hepatology Pub Date : 2025-03-13 DOI: 10.1016/j.cgh.2024.12.035

Mehdi Mohamadnejad, Mohammad Al-Haddad

引用次数: 0

Perspectives on the International Consensus for ASUC Clinical Trial Design: Enhancing Clarity and Applicability.

IF 11.6 1区医学

Clinical Gastroenterology and Hepatology Pub Date : 2025-03-13 DOI: 10.1016/j.cgh.2024.12.034

Arshdeep Singh, Vandana Midha, Ajit Sood

引用次数: 0

High Rates of Dysplasia in a Population-Based Analysis of "Incidental" Barrett's Esophagus.

IF 11.6 1区医学

Clinical Gastroenterology and Hepatology Pub Date : 2025-03-13 DOI: 10.1016/j.cgh.2025.01.017

Jennifer M Kolb, Christian Davis, J Lucas Williams, Jennifer Holub, Nicholas Shaheen, Sachin Wani

{"title":"High Rates of Dysplasia in a Population-Based Analysis of \"Incidental\" Barrett's Esophagus.","authors":"Jennifer M Kolb, Christian Davis, J Lucas Williams, Jennifer Holub, Nicholas Shaheen, Sachin Wani","doi":"10.1016/j.cgh.2025.01.017","DOIUrl":"10.1016/j.cgh.2025.01.017","url":null,"abstract":"Background and aims: Current screening and surveillance in Barrett's esophagus (BE) identifies only a minority of esophageal adenocarcinomas. Novel testing modalities may allow broadening of indications for BE screening. Whether such efforts are warranted depends on the characteristics of additional BE cases discovered, and their risk of progression. This study used national benchmarking data to characterize \"incidental\" BE.Methods: Upper endoscopies with BE in GI Quality Improvement Consortium (GIQuIC) Registry from 1/2015-7/2022 were categorized by indication: BE screening, surveillance, or non-BE-related (\"incidental\"). Demographics, disease-specific characteristics, and dysplasia detection rate (DDR: low and high-grade dysplasia) were compared, as well as adherence to quality indicators.Results: Of 88,370 cases (61.2% male, 74.0% white) with histologically-confirmed intestinal metaplasia, 88.1% were nondysplastic (NDBE). Most cases were performed for BE surveillance (65.0%). Incidental BE (16.4%) occurred almost as frequently as BE found in screening exams (18.6%). The mean BE segment length was longer in incidental BE (2.9cm) than BE screening (2.6) or surveillance (2.8, p<0.001). DDR was actually highest in incidental BE (3.8%), compared to surveillance or screening exams (2.5% and 3.3%, p<0.0001). Adherence to appropriate surveillance was similar in incidental and screening (54.5% and 51.9%), with higher adherence in surveillance group (73.6%, p<0.0001).Conclusion: BE is found incidentally at rates approaching those seen in dedicated screening exams. Incidental BE is not only common but has similar or worse high-risk features as BE in traditional screening and surveillance populations, given segment length and dysplasia yield. Refinement of BE screening programs could yield cases of similar risk of progression as traditional programs.","PeriodicalId":10347,"journal":{"name":"Clinical Gastroenterology and Hepatology","volume":" ","pages":""},"PeriodicalIF":11.6,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chyloperitoneum due to small bowel volvulus. 小肠旋涡造成的乳糜腹腔积液。

IF 11.6 1区医学

Clinical Gastroenterology and Hepatology Pub Date : 2025-03-13 DOI: 10.1016/j.cgh.2025.01.018

Zonglin Li, Yejiang Zhou, Linxia Xu

引用次数: 0

Processing mobility data through artificial intelligence can identify patterns of physical activity in liver transplant candidates.

IF 11.6 1区医学

Clinical Gastroenterology and Hepatology Pub Date : 2025-03-13 DOI: 10.1016/j.cgh.2025.01.019

Rachel Orbuch, Pamela M Bloomer, Ervic Sejdic, Wuqi Li, Andres Duarte-Rojo

引用次数: 0

Refining risk estimates of colorectal cancer in steatotic liver disease: Insights on methodological challenges.

IF 11.6 1区医学

Clinical Gastroenterology and Hepatology Pub Date : 2025-03-11 DOI: 10.1016/j.cgh.2025.02.002

Wei-Chun Cheng, Ching-Nung Wu, Pin-Nan Cheng

引用次数: 0

A comprehensive review of geriatric syndromes and assessment in older adults with inflammatory bowel diseases.

IF 11.6 1区医学

Clinical Gastroenterology and Hepatology Pub Date : 2025-03-11 DOI: 10.1016/j.cgh.2024.09.042

Margalida Calafat, Bharati Kochar, Ashwin N Ananthakrishnan

{"title":"A comprehensive review of geriatric syndromes and assessment in older adults with inflammatory bowel diseases.","authors":"Margalida Calafat, Bharati Kochar, Ashwin N Ananthakrishnan","doi":"10.1016/j.cgh.2024.09.042","DOIUrl":"10.1016/j.cgh.2024.09.042","url":null,"abstract":"Introduction: Older patients with inflammatory bowel disease (IBD) constitute an increasingly prevalent population. There is growing recognition of the prevalence and impact of geriatric syndromes on patients with IBD. We aimed to critically review available data on geriatric syndromes in patients with IBD.Methods: An electronic systematic bibliographic search was performed in April 2024 using PubMed to identify relevant literature on frailty, functional status assessment, and geriatric syndromes among older adults with IBD.Results: Frailty is prevalent among patients of all ages with IBD and is associated with worse outcomes. It is associated with an increased risk of infections but may be ameliorated through effective treatment of underlying inflammation. There is less understanding of other geriatric syndromes, such as multi-morbidity, polypharmacy, sarcopenia, fecal incontinence, physical function, falls, fatigue, social isolation and cognitive impairment in older patients with IBD; existing data suggests an important negative impact of all these syndromes on older adults with IBD.Conclusions: Geriatric syndromes are prevalent and negatively impact older patients with IBD. Systematic assessment for their presence and multidisciplinary interventions to improve them are important to improve outcomes of older adults with IBD.","PeriodicalId":10347,"journal":{"name":"Clinical Gastroenterology and Hepatology","volume":" ","pages":""},"PeriodicalIF":11.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

CHOLECYSTECTOMY IS A RISK FACTOR FOR MICROSCOPIC COLITIS: A NATIONWIDE POPULATION-BASED MATCHED CASE CONTROL STUDY.

IF 11.6 1区医学

Clinical Gastroenterology and Hepatology Pub Date : 2025-03-11 DOI: 10.1016/j.cgh.2024.12.032

David Bergman, Fahim Ebrahim, Jiangwei Sun, John Maret-Ouda, Björn Lindkvist, Anne Peery, Jonas F Ludvigsson

{"title":"CHOLECYSTECTOMY IS A RISK FACTOR FOR MICROSCOPIC COLITIS: A NATIONWIDE POPULATION-BASED MATCHED CASE CONTROL STUDY.","authors":"David Bergman, Fahim Ebrahim, Jiangwei Sun, John Maret-Ouda, Björn Lindkvist, Anne Peery, Jonas F Ludvigsson","doi":"10.1016/j.cgh.2024.12.032","DOIUrl":"https://doi.org/10.1016/j.cgh.2024.12.032","url":null,"abstract":"Background and aims: Studies have linked bile-acid malabsorption and microscopic colitis (MC), with some MC patients responding to treatment with bile-acid sequestrants. However, the literature on cholecystectomy as a risk factor for MC is inconclusive. Therefore, we investigated the relationship between cholecystectomy and MC on a nationwide scale to provide more definitive insights.Methods: We conducted a nationwide matched case-control study involving 13,554 patients diagnosed with MC between 1981 and 2017 in Sweden who were matched to 64,886 controls. Data on MC were obtained from Swedish pathology registers, and controls were randomly selected from the general population and matched according to birth year, sex, county of residence and calendar year. Moreover, MC-free full siblings to patients with MC were identified. Information on cholecystectomy was collected from the Swedish National Patient Register. Adjusted odds ratios (aORs) were calculated using multivariable-adjusted conditional logistic regression.Results: The median age at diagnosis was 63.5 years (interquartile range [IQR]=51.0-73.4), and 72.3% of MC patients were women. Among MC patients, 342 (2.5%) had undergone a cholecystectomy before diagnosis, compared to 687 (1.1%) in the control group. This yielded an aOR of 2.36 (95% CI=2.07-2.69) for earlier cholecystectomy in MC patients. The corresponding aORs for collagenous colitis and lymphocytic colitis were 1.87 (95% CI=1.48-2.36) and 2.65 (95% CI=2.26-3.12), respectively. When compared to siblings, the aOR was 1.49 (95% CI=1.21-1.85).Conclusions: Cholecystectomy is associated with an increased risk of subsequent MC. These findings have implications for surgeons and general practitioners and underscore the need for further research into the underlying association between bile-acid and microscopic colitis.","PeriodicalId":10347,"journal":{"name":"Clinical Gastroenterology and Hepatology","volume":" ","pages":""},"PeriodicalIF":11.6,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffuse esophageal uptake on ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography scan.

IF 11.6 1区医学

Clinical Gastroenterology and Hepatology Pub Date : 2025-03-11 DOI: 10.1016/j.cgh.2025.02.003

Christopher James Shephard, William Jiaen Wang, Bulent Baran

引用次数: 0

The Impact of Metabolic Dysfunction and Bariatric Surgery on Severity and Outcomes in Alcohol Associated Hepatitis.

IF 11.6 1区医学

Clinical Gastroenterology and Hepatology Pub Date : 2025-03-11 DOI: 10.1016/j.cgh.2024.12.031

Rosa Yang, Geetha Ramalingam, Yiwei Hang, Joseph Spengler, Ekaterina Smirnova, Richard K Sterling

引用次数: 0