Clinical and Experimental Allergy最新文献

{"title":"Radiation-Induced Skin Toxicity Risk in Breast Cancer Patients With Atopic or Allergic Conditions","authors":"Philong Nguyen, Julia Ding, Joshua Wang, Yena Jang, Joshua Borja, Gabriela Villa, Tiffany Cheng, Yousef Tanas, Wei-Chen Lee","doi":"10.1111/cea.70359","DOIUrl":"10.1111/cea.70359","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":"56 9","pages":"1093-1096"},"PeriodicalIF":5.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148136854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Effectiveness and Predictors of House Dust Mite Subcutaneous Immunotherapy in Polysensitised Patients With Allergic Rhinitis: A Multicentre Retrospective Study.","authors":"Maajid Mohi Ud Din Malik, Rajesh Prasad Jayaswal","doi":"10.1111/cea.70391","DOIUrl":"10.1111/cea.70391","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":"1144-1145"},"PeriodicalIF":5.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13532860/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148410581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Prehospital Care in Fatal Food Anaphylaxis: A Nationally Representative Case Series\".","authors":"","doi":"10.1111/cea.70402","DOIUrl":"10.1111/cea.70402","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":"1151"},"PeriodicalIF":5.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13532773/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148590704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Implications of Incidental Arg r 1 Sensitization Identified by Multiplex Allergy Testing.","authors":"Rabia Uysal, Melike Ocak, Ceren Ustun, Aysegul Ertugrul, Ozge Soyer, Bulent Enis Sekerel","doi":"10.1111/cea.70339","DOIUrl":"10.1111/cea.70339","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":"1125-1127"},"PeriodicalIF":5.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13532772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147926916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Memoriam: The Legacy of Professor Dietrich Kraft (1937–2026)","authors":"Debajyoti Ghosh","doi":"10.1111/cea.70401","DOIUrl":"https://doi.org/10.1111/cea.70401","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":"56 9","pages":"998-1000"},"PeriodicalIF":5.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148862260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bronchial Fibroblasts Respond to IL-4 Challenge With Cytokine Secretion: Role in Allergic Airway Inflammation.","authors":"Dong Zhang, Wei Liu, Qiuwen Chen, Shasha Han, Tao Wang, Qian Qi, Liang Dong, Xiaozhi Wang","doi":"10.1111/cea.70358","DOIUrl":"10.1111/cea.70358","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":"1134-1136"},"PeriodicalIF":5.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13532927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148013897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Population-Scale Plasma Proteomics Reveals Systemic Inflammatory Signatures Associated With Chronic Rhinosinusitis.","authors":"Dachan Kim, Hyung-Ju Cho, Chang-Hoon Kim, Min-Seok Rha","doi":"10.1111/cea.70344","DOIUrl":"10.1111/cea.70344","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":"1131-1133"},"PeriodicalIF":5.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13532874/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147986974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Feeding Difficulties in Children With Non-IgE Mediated Food Allergies: A Systematic Review.","authors":"Marianne Louise Tomlin, Cassandra Bendall, Paxton Loke, Christie Jane Bennett","doi":"10.1111/cea.70367","DOIUrl":"10.1111/cea.70367","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":"1117-1124"},"PeriodicalIF":5.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13532976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148315990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-Dose Intravenous Challenge Testing to Neuromuscular Blocking Agents: A Safe and Effective Approach to the Investigation of Perioperative Anaphylaxis. Comment on Clin Exp Allergy 2026;56:438-441.","authors":"Siraj A Misbah, Rachel C Pollard","doi":"10.1111/cea.70390","DOIUrl":"10.1111/cea.70390","url":null,"abstract":"","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":" ","pages":"1142-1143"},"PeriodicalIF":5.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13532980/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148403963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Basophil Histamine Content as a Biomarker for Omalizumab Responsiveness in Chronic Spontaneous Urticaria","authors":"Ditte Georgina Zhang, Katrine Baumann, Clive Grattan, Per Stahl Skov, Simon Francis Thomsen","doi":"10.1111/cea.70327","DOIUrl":"10.1111/cea.70327","url":null,"abstract":"<p>Patients with chronic spontaneous urticaria (CSU) exhibit varying treatment needs to achieve disease control with omalizumab, and adjustments to the standard dose of 300 mg every 4 weeks are common [<span>1</span>]. This calls for biomarkers that may aid physicians in tailoring a more personalised treatment approach [<span>2</span>]. Currently, no reliable biomarkers are available for this purpose. The basophil histamine release assay (BHRA) remains the single best biomarker for identifying (autoimmune) type IIb CSU, which tends to respond slower and less effectively to omalizumab treatment compared to (autoallergic) type I CSU [<span>3, 4</span>]. A previous study reported that low intracellular histamine content in basophils is associated with features of type IIb CSU [<span>5</span>]. This study therefore aimed to explore whether intracellular histamine content of basophils could serve as a stronger or complementary novel biomarker for predicting and monitoring treatment response, offering a simpler and less costly alternative to the BHRA.</p><p>A total of 164 adults with CSU who had total cellular blood histamine levels measured were included from the Chronic Urticaria COPenhagen cohort (CU-COP). Details on cohort recruitment and methods for assessing treatment response have been described previously [<span>1</span>]. Informed consent was obtained from all patients and approval was granted by local authorities (Ref. P-2020-318). According to Danish legislation, ethical committee approval was not required. Total cellular blood histamine levels were used to calculate the intracellular histamine content per basophil, as described in detail elsewhere [<span>3</span>]. Continuous variables are presented as medians with interquartile ranges (IQR), and categorical variables as proportions. Correlations between numerical variables were assessed using Spearman's rank correlation coefficient. Group differences were evaluated using the Wilcoxon rank-sum test, with a <i>p</i>-value < 0.05 considered statistically significant. All analyses were performed using <i>R</i> version 4.4.1 and R Studio.</p><p>Clinical characteristics of the study cohort are presented in the repository material. The previously reported association between intracellular histamine content per basophil and features of type IIb CSU was replicated. Among the entire cohort, 106 patients initiated omalizumab treatment, of whom 101 were omalizumab-naïve at baseline. Among these intracellular histamine content per basophil did not differ significantly across patients with fast (within 1 month), delayed (within 3 months) and late/non-response (after 3 months or no response during treatment) to treatment (Figure 1A). Likewise, the intracellular histamine content per basophil did not differ significantly across the overall treatment response groups when comparing patients with good (symptom-free or minor symptoms), partial (insufficient response) and poor response (no response) (Figure","PeriodicalId":10207,"journal":{"name":"Clinical and Experimental Allergy","volume":"56 9","pages":"1101-1103"},"PeriodicalIF":5.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/cea.70327","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}