María Cristina Neira-Moscoso, Juan Marcelo Rojas-Sánchez, Claudia Rodas-Espinoza, Diana Morillo, Susana Andrade, Cristina Ochoa, María José Molina, Mayra Parra, Angélica Ochoa
{"title":"[Prevalence of sensitization to dog and cat epithelia in preschool patients from urban areas of Cuenca, Ecuador].","authors":"María Cristina Neira-Moscoso, Juan Marcelo Rojas-Sánchez, Claudia Rodas-Espinoza, Diana Morillo, Susana Andrade, Cristina Ochoa, María José Molina, Mayra Parra, Angélica Ochoa","doi":"10.29262/ram.v72i2.1456","DOIUrl":"https://doi.org/10.29262/ram.v72i2.1456","url":null,"abstract":"<p><strong>Objective: </strong>To establish the prevalence of sensitization to dog and cat epithelium in a pediatric population aged 3 to 6 years.</p><p><strong>Methods: </strong>A descriptive, cross-sectional prevalence study was conducted as part of the study \"Prevalence and risk factors for asthma, rhinitis, eczema, and atopy among preschool children in an Andean city.\" The study population consisted of children from the city of Cuenca, Ecuador, who were administered the culturally validated ISAAC survey and underwent inhalant skin testing.</p><p><strong>Results: </strong>A total of 600 children were enrolled, with a prevalence of atopy of 33.45% (n = 179), sensitization to dog epithelium of 1.76% (n = 10), and sensitization to cat epithelium of 2.12% (n = 12), representing 5.59% and 6.70% of the atopic population, respectively.</p><p><strong>Conclusion: </strong>The prevalence of sensitization to cat and dog epithelium in children under 6 years of age is lower than expected in the clinical setting. Future studies should assess the sample size in relation to the prevalence of sensitization to cat and dog epithelium.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 2","pages":"93-98"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144586061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Edwin Daniel Maldonado-Domínguez, Víctor Fernando Muñoz-Estrada, Jaime Picazo-Luna
{"title":"[Low pseudoallergen and histamine diet: a therapeutic approach in patients with chronic spontaneous urticaria.]","authors":"Edwin Daniel Maldonado-Domínguez, Víctor Fernando Muñoz-Estrada, Jaime Picazo-Luna","doi":"10.29262/ram.v72i2.1452","DOIUrl":"https://doi.org/10.29262/ram.v72i2.1452","url":null,"abstract":"<p><strong>Background: </strong>This article analyzes the effects of a histamine- and pseudoallergen-restricted diet as an additional strategy in the treatment of chronic spontaneous urticaria (CSU). A comprehensive review of the literature was conducted using PubMed and Google Scholar, employing both MeSH and non-MeSH terms related to urticaria, histamine, and diet. The review included 78 selected articles published between 2014 and 2024. CSU is a persistent disease in which a considerable number of patients do not respond optimally to standard treatments. Up to one-third of these patients may benefit from reducing the intake of pseudoallergens and histamine-rich foods. Bioactive amines present in various foods tend to exacerbate CSU symptoms by promoting the release of histamine and other inflammatory mediators. The restriction of dietary histamine and the enhancement of diamine oxidase (DAO) enzyme function appear to alleviate symptoms, although variability in reported histamine levels across studies complicates the development of standardized guidelines. It is concluded that a low-histamine and pseudoallergen diet is a promising option for reducing symptoms in patients with chronic spontaneous urticaria (CSU), particularly those who do not achieve adequate control with antihistamines. Evaluating the effectiveness of this diet over a period of three to four weeks is recommended to observe potential benefits. Nevertheless, additional studies and further standardization are necessary to define safe histamine levels in foods and improve therapeutic recommendations.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 2","pages":"119-130"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144586059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Camila Castanier-Dávila, Paúl Leonardo Wilches-Coronel
{"title":"[Adverse drug reaction in a patient with autoimmune disease: Case report].","authors":"María Camila Castanier-Dávila, Paúl Leonardo Wilches-Coronel","doi":"10.29262/ram.v72i2.1446","DOIUrl":"https://doi.org/10.29262/ram.v72i2.1446","url":null,"abstract":"<p><strong>Background: </strong>Adverse drug reactions are harmful and unintentional events related to medication use. Stevens-Johnson Syndrome is a serious adverse drug reaction that can progress to toxic epidermal necrolysis and is related to certain medications. It can even be triggered by infections and genetic factors.</p><p><strong>Case report: </strong>A 62-year-old female patient with high blood pressure developed severe skin lesions after self-medicating with paracetamol and ibuprofen. She recovered favorably after several treatments and admissions to the Intensive Care Unit.</p><p><strong>Conclusion: </strong>It is important to promptly identify the triggering factors of adverse drug reactions in order to intervene appropriately. The administration of corticosteroids and IV immunoglobulin is still under discussion. Immediate attention is required to improve clinical outcomes and comprehensive treatment, thus optimizing the outcome.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 2","pages":"136-141"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144586058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Paulo Eduardo Silva Belluco, Marjorie Uber, Franciane de Paula da Silva, Júllia Eduarda Feijó Belluco, Kerstin Taniguchi Abagge, Rosana Zabulon Feijó Belluco, José Carlos Mori
{"title":"New cosmetics patch test series: A proposal.","authors":"Paulo Eduardo Silva Belluco, Marjorie Uber, Franciane de Paula da Silva, Júllia Eduarda Feijó Belluco, Kerstin Taniguchi Abagge, Rosana Zabulon Feijó Belluco, José Carlos Mori","doi":"10.29262/ram.v72i2.1437","DOIUrl":"https://doi.org/10.29262/ram.v72i2.1437","url":null,"abstract":"<p><strong>Background: </strong>Contact dermatitis to cosmetic products is a common condition. It is likely the most frequent reason for performing patch tests because many substances used in cosmetics are potent allergens. Cosmetic contact dermatitis most frequently affects the face. Patch test series need to be continuously revised to identify outdated and emerging allergens. The aim of this study is to propose a reformulation of the patch test series for cosmetics. The list of European Surveillance System on Contact Allergies was initially used to select the allergens. Publications in PubMed from the last 10 years were sought, showing the frequency of positive reactions to cosmetic allergens that were tested as part of a baseline series or cosmetics series. Subsequently, large international databases evaluating retail products were consulted to verify if these substances were present in cosmetics, because the relevance would be their presence in commercially sold cosmetics. It was adopted a threshold of 0.3% positive patch test reactions for including a substance in cosmetics series. It was deleted those present in the baseline series (Associação Brasileira de Alergia e Imunologia), fragrances, and allergens limited to hair products. It is believed that choosing too few allergens may result in the non-identification of relevant allergens and treatable cases. On the other hand, testing a series with many allergens is time-consuming and more costly. Therefore, it seems appropriate to create cosmetics series with 20 elements.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 2","pages":"107-118"},"PeriodicalIF":0.0,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144586066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlos Agustín León-Cortés, Eric Martínez-Infante, Rodolfo Francisco García-Caballero, Liliana Galicia-Rodríguez, Enrique Villarreal-Ríos, Jesús Elizarrarás-Rivas
{"title":"[Prevalence of allergic rhinitis in children aged 6 to 10 years treated in the Allergy service].","authors":"Carlos Agustín León-Cortés, Eric Martínez-Infante, Rodolfo Francisco García-Caballero, Liliana Galicia-Rodríguez, Enrique Villarreal-Ríos, Jesús Elizarrarás-Rivas","doi":"10.29262/ram.v72i1.1426","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1426","url":null,"abstract":"<p><strong>Objective: </strong>Determine the prevalence of allergic rhinitis in school children.</p><p><strong>Methods: </strong>Cross-sectional, descriptive study in children from 6 to 10 years old. Those who underwent skin testing (mites, pollens, fungi, cockroach, dog and cat hair) were included. The diagnosis of allergic rhinitis was made based on the test recommended by the European Academy of Allergy and Clinical Immunology (EAACI) and the American College of Allergy, Asthma and Immunology (ACAAI) for the diagnosis of allergy mediated by allergen-specific IgE. The statistical analysis included confidence interval for averages and percentages.</p><p><strong>Results: </strong>In the 992 patients, the prevalence of allergic rhinitis was 15.7% (95% CI; 13.4-18.0), the predominant symptom was hyaline rhinorrhea in 94.7% (95% CI; 91.4-94.6), the main allergen was dust mites 60.4% (95% CI; 52.7-68.1) and pollen 59.3% (95% CI; 51.6-67.0).</p><p><strong>Conclusion: </strong>The prevalence of allergic rhinitis in school children with positive skin tests is 15.7%, with a predominance of males with 63.1%.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"21-27"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Anaphylaxis due to Solanum betaceum].","authors":"Berta Valor-Llácer, Gaspar Dalmau-Duch, Vanessa Gázquez-García","doi":"10.29262/ram.v72i1.1422","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1422","url":null,"abstract":"<p><strong>Background: </strong>Tree tomato (Solanum betaceum or Cyphomandra betaceae) or tamarillo belongs to the Solanaceae family and is widely consumed in Latin American countries.</p><p><strong>Case report: </strong>We report the case of a 43-year-old male from Ecuador who suffered two systemic anaphylaxis after drinking tamarillo juice, with previous tolerance to tamarillo on several occasions. Allergology study showed positivity in prick-prick to tamarillo peel and pulp and negativity to other types. SDS-PAGE immunoblotting with peel-pulp and Western Blot showed multiple bands between 14-75 kDa in tamarillo peel and 11-75 kDa in pulp. ELISA inhibition showed that tamarillo only inhibited itself.</p><p><strong>Conclusions: </strong>Given the results and tolerance to other types of tomato, we believe that the causative protein could be selective, so we report the first case of primary sensitivity to Solanum betaceum (tamarillo).</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"80-83"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ileana María Madrigal-Beas, Jonathan Higgins Payan-Díaz, Alejandra Medina-Hernández, María Gracia Belinda Guerrero-Núñez, María de Los Angeles Juan-Pineda, Daniela Rivero-Yeverino, Blanca María Morfin-Maciel
{"title":"[Non-IgE-mediated gastrointestinal food allergy. Updated literature review by the CMICA Food Allergy Committee].","authors":"Ileana María Madrigal-Beas, Jonathan Higgins Payan-Díaz, Alejandra Medina-Hernández, María Gracia Belinda Guerrero-Núñez, María de Los Angeles Juan-Pineda, Daniela Rivero-Yeverino, Blanca María Morfin-Maciel","doi":"10.29262/ram.v72i1.1420","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1420","url":null,"abstract":"<p><strong>Background: </strong>Non-IgE-mediated gastrointestinal food allergy includes adverse reactions to food mediated by the innate immune system and cellular immunity. It is characterized by subacute or chronic gastrointestinal symptoms after ingestion of a relevant food allergen, making diagnosis difficult.</p><p><strong>Objective: </strong>To carry out an updated bibliographic review of non-IgE-mediated gastrointestinal food allergy, that summarizes incidence, pathophysiology, clinical manifestations, diagnostic tools and treatment.</p><p><strong>Methodolgy: </strong>A search was conducted in the databases Medline, EMBASE, Scielo, Google Scholar and the Advanced Medicine Informatics Network (RIMA) using the keywords: non-IgE-mediated food allergy, allergic proctocolitis; cow's milk-induced anemia; food protein-induced enteropathy; food protein-induced enterocolitis syndrome; Celiac disease and Heiner syndrome. The search was limited to articles published in English and Spanish from January 2015 to May 2024.</p><p><strong>Results: </strong>While progress has been made in the recognition of these diseases, the prevalence and pathophysiology remain uncertain. Involvement of the innate immune system and cellular immunity in gastrointestinal inflammation has been found, but further studies are needed to clarify the immunopathogenesis and associated biomarkers.</p><p><strong>Conclusions: </strong>Non-IgE-mediated gastrointestinal food allergy account for an unknown proportion of food allergies. Since there are no biomarkers or non-invasive confirmatory tests, the diagnosis relies on clinical features and is confirmed when the symptoms improve with elimination of the offending food. Management includes avoidance of the causative food from the diet, supportive treatment in case of accidental exposure, and nutritional counseling.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"35-61"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rosalaura Virginia Villarreal-González, Pablo Perea-Valle, Alira Fraga-Olvera, Anabel Ávila-Lara, Angélica Delgado-Bafuelos, Carlos Alberto Correa-Serrano, Carolina García-Rosas, César Daniel Alonso-Bello, Germán Agustín Rico-Solis, Itzel Vianey Ochoa-García, Jennifer Ramírez-Heredia, Kitzia González-Juárez, Maciel Monserrat Moreno-González, Margarita Ortega-Cisneros, María de la Luz Hortensia García-Cruz, María Isabel Arias-Martínez, Nayell Servín-Suárez, Rosa María Cortés-Grimaldo, Silvia Paulina Ruiz-López, Yahvén Zecua-Nájera, Diana Estefanía Cadenas-García
{"title":"[Adverse reactions due to monoclonal antibodies in the treatment of allergic diseases. Group Positioning: Comité de Alergia a Medicamentos del Colegio Mexicano de Inmunología Clínica y Alergia (CMICA 2024-2025)].","authors":"Rosalaura Virginia Villarreal-González, Pablo Perea-Valle, Alira Fraga-Olvera, Anabel Ávila-Lara, Angélica Delgado-Bafuelos, Carlos Alberto Correa-Serrano, Carolina García-Rosas, César Daniel Alonso-Bello, Germán Agustín Rico-Solis, Itzel Vianey Ochoa-García, Jennifer Ramírez-Heredia, Kitzia González-Juárez, Maciel Monserrat Moreno-González, Margarita Ortega-Cisneros, María de la Luz Hortensia García-Cruz, María Isabel Arias-Martínez, Nayell Servín-Suárez, Rosa María Cortés-Grimaldo, Silvia Paulina Ruiz-López, Yahvén Zecua-Nájera, Diana Estefanía Cadenas-García","doi":"10.29262/ram.v72i1.1433","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1433","url":null,"abstract":"<p><strong>Background: </strong>Monoclonal antibodies are a therapeutic option for allergy, autoimmune, oncological diseases, among others, and work by inhibiting interactions between effector molecules and their specific receptors. However, the increasing use of these drugs has led to an increase in adverse drug reactions (ADRs). ADRs are defined as unexpected responses to therapeutic treatments. They are divided into type A, derived from the pharmacokinetics of the treatment or as a host immune response type B.</p><p><strong>Objectives: </strong>Review of the use of monoclonal antibodies in the treatment of allergic diseases, addressing key aspects such as pharmacokinetics, pharmacodynamics, posology, contraindications and adverse reactions.</p><p><strong>Methodology: </strong>A search of major medical databases on monoclonal antibodies for the treatment of allergic diseases was conducted. It was limited to original articles in English and Spanish, published between 2014 and 2024.</p><p><strong>Results: </strong>Monoclonal antibodies for allergic diseases are described, including their mechanism of action, trade name, indications, posology, contraindications and adverse reactions.</p><p><strong>Conclusion: </strong>The collection of data on biological drugs is crucial for a comprehensive and up-to-date understanding of their clinical use. Understanding adverse reactions improves diagnosis and the quality of medical care.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"52-71"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Isabel Rojo-Gutiérrez, Carol Vivian Moncayo-Coello, Verónica Fernández Sánchez, Diego Ballesteros-González, Dulce Milagros Razo Blanco-Hernández
{"title":"[Frequency of signs and symptoms in the Post-COVID Syndrome of subjects partially or fully recovered from COVID-19].","authors":"María Isabel Rojo-Gutiérrez, Carol Vivian Moncayo-Coello, Verónica Fernández Sánchez, Diego Ballesteros-González, Dulce Milagros Razo Blanco-Hernández","doi":"10.29262/ram.v72i1.1388","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1388","url":null,"abstract":"<p><strong>Objetives: </strong>To evaluate the persistent symptoms in subjects with infection of COVID-19, partially or fully recovered.</p><p><strong>Methods: </strong>An observational, descriptive, cross-sectional, prospective study was conducted in individuals who were infected with SARS-CoV-2. We included Individuals of any gender and age who voluntarily answer a survey after developing infection to identify signs and symptoms associated, we analyzed whether there was any relationship between female sex and obesity, or age related with post-COVID-19 syndrome by X<sup>2</sup> test and t Student test.</p><p><strong>Results: </strong>197 individuals were included with mean age 41.57 (SD 14.2 years), 61.9% were female. Post-COVID syndrome was present in 52.3%, depression, anosmia, dysgeusia, nausea, alopecia and behavior disorders were greater in women; arthralgia, dyspnea, cough, and odynophagia were greater in obesity being statistically significant (p<0.05).</p><p><strong>Conclusions: </strong>Post-COVID syndrome was found in 52.3%, with a variety of symptoms female sex had a higher risk of presenting post-Covid syndrome with symptoms such as depression, behavior disorders, anosmia, and baldness.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"8-13"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}