Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)最新文献

{"title":"[Prevalence of allergic rhinitis in children aged 6 to 10 years treated in the Allergy service].","authors":"Carlos Agustín León-Cortés, Eric Martínez-Infante, Rodolfo Francisco García-Caballero, Liliana Galicia-Rodríguez, Enrique Villarreal-Ríos, Jesús Elizarrarás-Rivas","doi":"10.29262/ram.v72i1.1426","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1426","url":null,"abstract":"<p><strong>Objective: </strong>Determine the prevalence of allergic rhinitis in school children.</p><p><strong>Methods: </strong>Cross-sectional, descriptive study in children from 6 to 10 years old. Those who underwent skin testing (mites, pollens, fungi, cockroach, dog and cat hair) were included. The diagnosis of allergic rhinitis was made based on the test recommended by the European Academy of Allergy and Clinical Immunology (EAACI) and the American College of Allergy, Asthma and Immunology (ACAAI) for the diagnosis of allergy mediated by allergen-specific IgE. The statistical analysis included confidence interval for averages and percentages.</p><p><strong>Results: </strong>In the 992 patients, the prevalence of allergic rhinitis was 15.7% (95% CI; 13.4-18.0), the predominant symptom was hyaline rhinorrhea in 94.7% (95% CI; 91.4-94.6), the main allergen was dust mites 60.4% (95% CI; 52.7-68.1) and pollen 59.3% (95% CI; 51.6-67.0).</p><p><strong>Conclusion: </strong>The prevalence of allergic rhinitis in school children with positive skin tests is 15.7%, with a predominance of males with 63.1%.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"21-27"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A critical review of methodologies for evaluating annual direct medical costs of asthma management.","authors":"Hela Cherif, Salma Mokaddem","doi":"10.29262/ram.v72i1.1416","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1416","url":null,"abstract":"","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"84-85"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Anaphylaxis due to Solanum betaceum].","authors":"Berta Valor-Llácer, Gaspar Dalmau-Duch, Vanessa Gázquez-García","doi":"10.29262/ram.v72i1.1422","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1422","url":null,"abstract":"<p><strong>Background: </strong>Tree tomato (Solanum betaceum or Cyphomandra betaceae) or tamarillo belongs to the Solanaceae family and is widely consumed in Latin American countries.</p><p><strong>Case report: </strong>We report the case of a 43-year-old male from Ecuador who suffered two systemic anaphylaxis after drinking tamarillo juice, with previous tolerance to tamarillo on several occasions. Allergology study showed positivity in prick-prick to tamarillo peel and pulp and negativity to other types. SDS-PAGE immunoblotting with peel-pulp and Western Blot showed multiple bands between 14-75 kDa in tamarillo peel and 11-75 kDa in pulp. ELISA inhibition showed that tamarillo only inhibited itself.</p><p><strong>Conclusions: </strong>Given the results and tolerance to other types of tomato, we believe that the causative protein could be selective, so we report the first case of primary sensitivity to Solanum betaceum (tamarillo).</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"80-83"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Non-IgE-mediated gastrointestinal food allergy. Updated literature review by the CMICA Food Allergy Committee].","authors":"Ileana María Madrigal-Beas, Jonathan Higgins Payan-Díaz, Alejandra Medina-Hernández, María Gracia Belinda Guerrero-Núñez, María de Los Angeles Juan-Pineda, Daniela Rivero-Yeverino, Blanca María Morfin-Maciel","doi":"10.29262/ram.v72i1.1420","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1420","url":null,"abstract":"<p><strong>Background: </strong>Non-IgE-mediated gastrointestinal food allergy includes adverse reactions to food mediated by the innate immune system and cellular immunity. It is characterized by subacute or chronic gastrointestinal symptoms after ingestion of a relevant food allergen, making diagnosis difficult.</p><p><strong>Objective: </strong>To carry out an updated bibliographic review of non-IgE-mediated gastrointestinal food allergy, that summarizes incidence, pathophysiology, clinical manifestations, diagnostic tools and treatment.</p><p><strong>Methodolgy: </strong>A search was conducted in the databases Medline, EMBASE, Scielo, Google Scholar and the Advanced Medicine Informatics Network (RIMA) using the keywords: non-IgE-mediated food allergy, allergic proctocolitis; cow's milk-induced anemia; food protein-induced enteropathy; food protein-induced enterocolitis syndrome; Celiac disease and Heiner syndrome. The search was limited to articles published in English and Spanish from January 2015 to May 2024.</p><p><strong>Results: </strong>While progress has been made in the recognition of these diseases, the prevalence and pathophysiology remain uncertain. Involvement of the innate immune system and cellular immunity in gastrointestinal inflammation has been found, but further studies are needed to clarify the immunopathogenesis and associated biomarkers.</p><p><strong>Conclusions: </strong>Non-IgE-mediated gastrointestinal food allergy account for an unknown proportion of food allergies. Since there are no biomarkers or non-invasive confirmatory tests, the diagnosis relies on clinical features and is confirmed when the symptoms improve with elimination of the offending food. Management includes avoidance of the causative food from the diet, supportive treatment in case of accidental exposure, and nutritional counseling.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"35-61"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Adverse reactions due to monoclonal antibodies in the treatment of allergic diseases. Group Positioning: Comité de Alergia a Medicamentos del Colegio Mexicano de Inmunología Clínica y Alergia (CMICA 2024-2025)].","authors":"Rosalaura Virginia Villarreal-González, Pablo Perea-Valle, Alira Fraga-Olvera, Anabel Ávila-Lara, Angélica Delgado-Bafuelos, Carlos Alberto Correa-Serrano, Carolina García-Rosas, César Daniel Alonso-Bello, Germán Agustín Rico-Solis, Itzel Vianey Ochoa-García, Jennifer Ramírez-Heredia, Kitzia González-Juárez, Maciel Monserrat Moreno-González, Margarita Ortega-Cisneros, María de la Luz Hortensia García-Cruz, María Isabel Arias-Martínez, Nayell Servín-Suárez, Rosa María Cortés-Grimaldo, Silvia Paulina Ruiz-López, Yahvén Zecua-Nájera, Diana Estefanía Cadenas-García","doi":"10.29262/ram.v72i1.1433","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1433","url":null,"abstract":"<p><strong>Background: </strong>Monoclonal antibodies are a therapeutic option for allergy, autoimmune, oncological diseases, among others, and work by inhibiting interactions between effector molecules and their specific receptors. However, the increasing use of these drugs has led to an increase in adverse drug reactions (ADRs). ADRs are defined as unexpected responses to therapeutic treatments. They are divided into type A, derived from the pharmacokinetics of the treatment or as a host immune response type B.</p><p><strong>Objectives: </strong>Review of the use of monoclonal antibodies in the treatment of allergic diseases, addressing key aspects such as pharmacokinetics, pharmacodynamics, posology, contraindications and adverse reactions.</p><p><strong>Methodology: </strong>A search of major medical databases on monoclonal antibodies for the treatment of allergic diseases was conducted. It was limited to original articles in English and Spanish, published between 2014 and 2024.</p><p><strong>Results: </strong>Monoclonal antibodies for allergic diseases are described, including their mechanism of action, trade name, indications, posology, contraindications and adverse reactions.</p><p><strong>Conclusion: </strong>The collection of data on biological drugs is crucial for a comprehensive and up-to-date understanding of their clinical use. Understanding adverse reactions improves diagnosis and the quality of medical care.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"52-71"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Frequency of signs and symptoms in the Post-COVID Syndrome of subjects partially or fully recovered from COVID-19].","authors":"María Isabel Rojo-Gutiérrez, Carol Vivian Moncayo-Coello, Verónica Fernández Sánchez, Diego Ballesteros-González, Dulce Milagros Razo Blanco-Hernández","doi":"10.29262/ram.v72i1.1388","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1388","url":null,"abstract":"<p><strong>Objetives: </strong>To evaluate the persistent symptoms in subjects with infection of COVID-19, partially or fully recovered.</p><p><strong>Methods: </strong>An observational, descriptive, cross-sectional, prospective study was conducted in individuals who were infected with SARS-CoV-2. We included Individuals of any gender and age who voluntarily answer a survey after developing infection to identify signs and symptoms associated, we analyzed whether there was any relationship between female sex and obesity, or age related with post-COVID-19 syndrome by X² test and t Student test.</p><p><strong>Results: </strong>197 individuals were included with mean age 41.57 (SD 14.2 years), 61.9% were female. Post-COVID syndrome was present in 52.3%, depression, anosmia, dysgeusia, nausea, alopecia and behavior disorders were greater in women; arthralgia, dyspnea, cough, and odynophagia were greater in obesity being statistically significant (p<0.05).</p><p><strong>Conclusions: </strong>Post-COVID syndrome was found in 52.3%, with a variety of symptoms female sex had a higher risk of presenting post-Covid syndrome with symptoms such as depression, behavior disorders, anosmia, and baldness.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"8-13"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Delayed hypersensitivity and its relationship with the nutritional status of older adult women].","authors":"José Luis Gálvez-Romero, Natali Loranca-González, Ángel Ethian Meraz-Portilla, Gabriela Odette Hernández-Briones, Rosaura Olivos-Rodríguez, Enrique Pérez-Romero","doi":"10.29262/ram.v72i1.1436","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1436","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the relationship between cellular immune response, assessed through delayed hypersensitivity intradermal tests, and nutritional status in older adult women.</p><p><strong>Methods: </strong>A correlational observational study was conducted on elderly women, without evidence of infection, with an average age of 69.2 ± 5.9 years. Nutritional status was assessed using the Mini Nutritional Assessment (MNA) scale, and the in vivo cell-mediated immune response was measured through delayed hypersensitivity tests to various microbial antigens.</p><p><strong>Results: </strong>A total of 36 older adult women were enrolled in the study. Of these, 83.3% had a normal nutritional status, while 16.7% were at risk of malnutrition, with an average MNA score of 25.6 ± 2.7. The intradermal reaction test at 48 hours, showed an induration greater than 5 mm in 58.3% for Gram-positive bacteria, 38.9% for tetanus/diphtheria, 66.7% for candidin, and 0% for Escherichia coli. A positive response to candidin was more frequent in women at risk of malnutrition (OR: 1.3: CI_95%: 1.1 - 1.7; p = 0.05). After 96 hours, a candidin induration greater than 7 mm showed an area under the ROC curve of 0.75 (CI_95%: 0.57 - 0.94; p = 0.05) for predicting the risk of malnutrition.</p><p><strong>Conclusion: </strong>Older adult women with good nutritional status maintain an adequate cellular immune response, whereas those at risk of malnutrition exhibit greater reactivity to candidin, suggesting a possible immunological alteration associated with malnutrition.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"28-34"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Profile of sensitization to aeroallergens in patients with allergic rhinitis].","authors":"Joseline González-Martínez, Giovanni Sorcia-Ramírez, María José Muñoz-Pérez","doi":"10.29262/ram.v72i1.1394","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1394","url":null,"abstract":"<p><strong>Objective: </strong>To determine the prevalence and evaluate the distribution of sensitization to aeroallergens in pediatric and adult patients with allergic rhinitis.</p><p><strong>Methods: </strong>Observational, cross-sectional and retrospective study, carried out from the analysis of clinical records of patients with skin tests, to intentionally identify signs and symptoms of allergic rhinitis, as well as aeroallergens to which they reacted positively.</p><p><strong>Results: </strong>1531 skin reactivity tests were reviewed, of which 983 corresponded to patients with a diagnosis of allergic rhinitis with a positive test. The prevalence of the disease was 64.2% (n = 983); the pediatric population had a prevalence of 55.8% (n = 549) and the adult population 44.1% (n = 434). The aeroallergens with the higest frequency of sensitization were: Dermatophagoides pteronyssinus (59.5%), Dermatophagoides farinae (45.3%), cat (26.1%), Cupressus arizonica (21.7%), dog (21.6%) and Fraxinus excelsior ([Ash], 19.6%).</p><p><strong>Conclusion: </strong>There is a high prevalence of allergic rhinitis in the studied cohort. The house dust mites Dermatophagoides mix (Pteronyssinus and Farinae) were the main allergens. Cosensitization to cat and dog was high. The tree pollen species with the highest impact were: Cupressus arizonica, Fraxinus excelsior and Quercus robur (Roble, Encino, Oak). The grass pollen varieties with the greatest influence: Cynodon dactylon (Bermuda, Capriola) and Lolium Perenne (English grass).</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Honney Allergy].","authors":"María Belén Delavalle, Lucía Moreno-Lozano","doi":"10.29262/ram.v72i1.1419","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1419","url":null,"abstract":"<p><strong>Background: </strong>The main cause of allergy to honey is linked to the head of the bee.</p><p><strong>Case report: </strong>A 44-year-old man with no relevant history presented with pharyngeal, palmo-plantar and axillary itching, dysphagia, dizzinessa nd sweating after ingesting honey. Addiotionally, when he drinks banana yogurt and cow's milk smoothie he notices slight pharyngeal itching. Normal basal tryptase (5.03 ug/L), total IgE 212.2 kU/L, IgEs: honey 37.3 and Apis 0.69 kU/L. SDS-PAGE and immunoblot of honey and banana yogurt extracts with the presence of bands between 12 to 70 kDa (honey); 12 to 35 kDa (banana yogurt) and SDS-PAGE and immunoblot of bee venom extract with the presence of bands from 10 to 50 kDa and the patient's serum recognized two proteins: one compatible with the major allergen Api m 1 at 16 kDa and another compatible with Api m 11 at 50 kDa.</p><p><strong>Conclusion: </strong>The patient is sensitized to several honey proteins (2 between 50-75 kDa and 1 between 20-25 kDa). He doesn't recognize any protein in the banana yogurt. Additionally, the patient recognizes a bee venom protein of about 50 kDa (compatible with Api m 11), and this may be the primary sensitization pathway.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"72-75"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Successful subcutaneous desensitization in a patient with systemic reaction due to ixekizumab].","authors":"Diego Gutiérrez-Fernández, Mónica Saldaña-Valderas, Marianela Iriarte-Gahete, Raquel De la Varga-Martínez, Rafael Pamies-Espinosa, Jose Carlos Roldán-Morales, Zahira Maria Franzón-Laz, Joan Doménech-W","doi":"10.29262/ram.v72i1.1424","DOIUrl":"https://doi.org/10.29262/ram.v72i1.1424","url":null,"abstract":"<p><strong>Background: </strong>Ixekizumab is a high-affinity IgG4 monoclonal humanized antibody useful for the treatment of ankylosing spondylitis. Benign skin reactions are a common adverse event with ixekizumab but systemic hypersensitivity reactions are much more unusual.</p><p><strong>Case report: </strong>We describe the case of a 54-female patient with HLAB27+ spondyloarthritis. Treatment with ixekizumab 80 mg subcutaneous (containing polysorbate) was prescribed. The patient experienced immediate severe dyspnea, skin erythema and flushing. Intradermal test (0.8 mg/ml) was clearly positive in the immediate reading. The patient was planned to undergo ixekizumab desensitization according to an 8-step protocol with good tolerance.</p><p><strong>Conclusion: </strong>We report a patient with HLAB27+ spondyloarthritis treated with ixekizumab who developed a systemic IgE-mediated reaction. A successful and easy to perform subcutaneous desensitization protocol is described.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"72 1","pages":"76-79"},"PeriodicalIF":0.0,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}