Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)最新文献

{"title":"Main trees in the Guadalajara Metropolitan Area and their relationship with pollen allergy.","authors":"Francisco Javier González Torres","doi":"10.29262/ram.v73i2.1608","DOIUrl":"10.29262/ram.v73i2.1608","url":null,"abstract":"<p><strong>Objective: </strong>Identify the main tree species of the Guadalajara Metropolitan Area and their relationship with allergies.</p><p><strong>Methods: </strong>Observational, cross-sectional and descriptive study, carried out with the intention of identifying the trees. An inventory of the most frequent trees from the AMG urban tree database was carried out and the species with the highest relationship to allergic diseases were identified.</p><p><strong>Results: </strong>A total of 49,138 trees were identified; the most common species were the Ficus, Orange Tree, Palm, Cypress, Guava and Ash. Of the 15 most common species, Cypress, Ash, Casuarina, Eucalyptus, and Thunder are of greater allergology relevance.</p><p><strong>Conclusions: </strong>Due to the increase in allergic diseases, such as allergy to tree pollen, it is important to have inventories that identify the species that may be related to these conditions, both for allergists and health authorities.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"73 2","pages":"e188-e194"},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148428035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asthma mortality in Colombia: a three-decade analysis and the effect of the COVID-19 pandemic.","authors":"Josefina Zakzuk, Luis Caraballo, Nelson Alvis Guzmán","doi":"10.29262/ram.v73i2.1597","DOIUrl":"10.29262/ram.v73i2.1597","url":null,"abstract":"<p><strong>Objectives: </strong>To describe asthma mortality trends in Colombia from 1990 to 2021 and to assess the impact of the COVID-19 pandemic during the 2020-2021 period.</p><p><strong>Methods: </strong>A retrospective and observational study, carried out from the analysis of Global Burden of Disease 2021, was used to estimate age-standardized prevalence, mortality, and disability-adjusted life years (DALYs) for asthma in Colombia. Additionally, crude asthma mortality data for the period 2015-2023 were obtained from the National Department of Statistics of Colombia (DANE). Temporal trends were assessed using Joinpoint regression, and crude mortality rates before and during the COVID-19 pandemic were compared to estimate excess mortality.</p><p><strong>Results: </strong>A significant decline in asthma mortality was observed in Colombia between 1990 and 2021 (average annual percent change [AAPC]: -1.5%; 95%CI: -1.7 to -1.3), consistent with global trends. However, during 2020-2021, asthma-related mortality in Colombia increased from 0.43 to 0.63 per 100,000 population compared with the 2015-2019 period (RR = 1.49; 95% CI: 1.35-1.64), with a greater relative increase among individuals older than 65 years.</p><p><strong>Conclusions: </strong>Despite sustained reductions in asthma mortality over three decades in Colombia, the COVID-19 pandemic was associated with a substantial increase in asthma-related deaths, highlighting the importance of maintaining continuity of care for chronic diseases during public health emergency.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"73 2","pages":"e137-e152"},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148427910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Satisfaction assessment with subcutaneous immunotherapy by ESPIA questionnaire in a pediatric population with allergic phenotype asthma.","authors":"Javier Hernández Romero, Rodrigo Collado Chagoya, Andrea Velasco Medina, Guillermo Velázquez Sámano, Omar Delgado Martinez","doi":"10.29262/ram.v73i2.1591","DOIUrl":"10.29262/ram.v73i2.1591","url":null,"abstract":"<p><strong>Objective: </strong>Assess satisfaction with subcutaneous immunotherapy in patients with asthma, by using the Satisfaction Scale for Patients Receiving Allergen Immunotherapy (ESPIA) questionnaire which was validated in Spanish language.</p><p><strong>Methods: </strong>A cross-sectional, observational, unicenter study was carried out in a National Allergy Reference Center in Mexico in patients older than 6 years of age, diagnosed with Allergic Asthma with positive allergy biomarkers (IgE, Skin Tests, Nasal Mucus Cytology, Eosinophils in Blood) with a mild or moderate severity classification with a Subcutaneous Immunotherapy scheme lasting a minimum of 12 months. The level of satisfaction was assessed during the treatment by the ESPIA questionnaire, and the level of control was measured by using the Asthma Control Test. The correlation between the characteristics of the population, the control of the disease, the severity of the disease and the satisfaction with the treatment was analyzed using the ANOVA test (categorical variables) or the Pearson and Spearman coefficients correlation (continuous variables).</p><p><strong>Results: </strong>A total of 147 patients (mean age 10.08 years, range 4-17 years, 82 men [56%]) were included in the study. Among them 122 (82.9%) suffered some type of comorbidity. The average Score of the ESPIA questionnaire to measure Satisfaction of treatment with Subcutaneous Immunotherapy was 87.12. No statistical differences were found in treatment satisfaction between men and women (p>0.05) and between polysensitized patients with more than 3 allergens and with less than 3 allergens. (p>0.05). There was a lower level of satisfaction with Immunotherapy measured with the ESPIA questionnaire in patients with comorbidity of Atopic Dermatitis. A correlation was demonstrated between levels of disease control and levels of satisfaction with treatment with Subcutaneous Immunotherapy measured with the ESPIA Questionnaire.</p><p><strong>Conclusion: </strong>Subcutaneous allergen immunotherapy was associated with high treatment satisfaction in pediatric patients with allergic asthma. Treatment satisfaction showed a positive correlation with asthma control, supporting the clinical relevance of patient-reported outcomes in the evaluation of immunotherapy effectiveness.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"73 2","pages":"e120-e128"},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148428060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hymenoptera allergy, difficulties in differential diagnosis: a case report.","authors":"Jimena Laiseca García, Gabriela Pretre, Alfedo Iglesias Cadarso, Miriam Barrios Albajar","doi":"10.29262/ram.v73i2.1586","DOIUrl":"https://doi.org/10.29262/ram.v73i2.1586","url":null,"abstract":"<p><strong>Background: </strong>The diagnosis of hymenoptera venom allergy can be particularly challenging, with the clinical history serving as a fundamental tool to guide the identification of the culprit insect. However, patient-reported visual recognition is often inaccurate and may lead to diagnostic errors unless supported by specific immunoallergological testing.</p><p><strong>Case report: </strong>A 37-year-old man who, during a stay in Taramundi (Asturias, Spain), sustained an insect sting that he visually identified as <i>Nomada flava</i>. Ten minutes later, he developed Müller grade III anaphylaxis, with loss of consciousness, angioedema, and vomiting. The allergologic evaluation revealed double sensitization to <i>Vespula spp</i>. and <i>Polistes dominula</i> through skin testing and specific IgE measurement, with no evidence of sensitization to <i>Apis mellifera</i>. Immunoblot analysis demonstrated serum reactivity directed against <i>Polistes dominula</i> venom, mainly to component Pol d 1. Based on these findings, a diagnosis of <i>Polistes dominula</i> venom allergy was established, and species-specific venom immunotherapy was prescribed. The patient was also diagnosed with mast cell activation syndrome, confirmed by bone marrow examination.</p><p><strong>Conclusion: </strong>This case underscores the need for a comprehensive allergologic workup to accurately identify the implicated species and guide appropriate venom immunotherapy, as patient-reported visual recognition of the stinging insect may be unreliable.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"73 2","pages":"e201-e205"},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148428002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genetic variants of <i>TNF-α</i> and <i>PTPN22</i> and their association with Hashimoto's thyroiditis in patients with chronic spontaneous urticaria from the Colombian Caribbean.","authors":"Carlos Octavio Arroyo Movilla, Alex Domínguez Vargas, Luis Fang, Ana Moreno Woo, Gloria Garavito De Egea, Eduardo Egea Bermejo","doi":"10.29262/ram.v73i2.1585","DOIUrl":"https://doi.org/10.29262/ram.v73i2.1585","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the association of <i>TNF-α</i> promoter polymorphisms (rs361525, rs1800629) and the <i>PTPN22</i> rs2476601 variant with the coexistence of CSU and HT in an admixed Caribbean Colombian population.</p><p><strong>Methods: </strong>A retrospective case-control study was conducted in 86 patients with confirmed CSU (45 with CSU-alone and 41 with CSU+HT). Single-nucleotide polymorphism (SNP) genotyping was performed using TaqMan^® assays. Hardy-Weinberg equilibrium (HWE), genotype, and allele frequencies were analyzed using chi-square tests and logistic regression models.</p><p><strong>Results: </strong>The <i>PTPN22</i> G allele showed a protective association in the CSU+HT group (OR: 0.02, 95% CI: 0.00-0.49; p = 0.015). While <i>TNF-α</i> SNPs conformed to HWE, <i>PTPN22</i> deviated in the CSU+HT group due to the complete absence of AG heterozygotes. No significant associations were found between <i>TNF-α</i> polymorphisms and HT, though the <i>TNF-α</i> rs361525 G allele exhibited a near-significant trend (p = 0.061). The GG genotype was predominant across all evaluated SNPs.</p><p><strong>Conclusion: </strong>In this admixed Caribbean Colombian study, we observed a hypothesis-generating association between the <i>PTPN22</i> rs2476601 G allele and lower odds of concomitant HT in CSU patients. Larger, adequately powered studies incorporating rigorous ancestry adjustment are required to confirm this finding.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"73 2","pages":"e111-e119"},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148427931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spanish translation and cross-cultural adaptation of a new severity scale to measure activity in patients with chronic prurigo: Prurigo Control Test (PCT).","authors":"Ana Clara Torre, Agustin Wagner, Sergio Adrián Terrasa, Anama Di Prinzio, Nadia Bejar, María Valeria Ángles, Luis Daniel Mazzuoccolo","doi":"10.29262/ram.v73i2.1603","DOIUrl":"https://doi.org/10.29262/ram.v73i2.1603","url":null,"abstract":"<p><strong>Objective: </strong>Perform the translation and cross-cultural adaptation of the severity scale to measure activity in patients with chronic prurigo: Prurigo Control Test (PCT) for the locality of Río de la Plata, Argentina.</p><p><strong>Methods: </strong>A cross-sectional study using a mixed-methods (qualitative and quantitative) approach was performed. The process involved seven stages: translation, expert reconciliation, back-translation into English, equivalence review, expert evaluation, cognitive interviews with patients, and development of the final version.</p><p><strong>Results: </strong>A Spanish version of the questionnaire was obtained. Eleven patients were interviewed. The median age was 70 years (IQR 59-75), and the median disease duration was 24 months. Correct comprehension of all items was achieved by 90% of the patients. The only modification made was the addition of the clarification \"(de la piel)\" [of the skin] following the term \"cutánea\" [cutaneous] to ensure comprehension across all educational levels.</p><p><strong>Conclusions: </strong>The translated and adapted version of the PCT constitutes a simple, objective, and valuable tool for assessing disease control and therapeutic response in the daily clinical care of Spanish-speaking patients.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"73 2","pages":"e153-e164"},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148428049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kikuchi-Fujimoto disease associated with systemic lupus erythematosus in an adolescent patient: case report and diagnostic challenges.","authors":"Alan Orlando Morales Reyes, Karla Mitchell Rodríguez García, Anette Michelle Ávila Silva, Christian Jair Ramos Gómez, Estefanía Medina Aguilar","doi":"10.29262/ram.v73i2.1583","DOIUrl":"https://doi.org/10.29262/ram.v73i2.1583","url":null,"abstract":"<p><strong>Background: </strong>Kikuchi-Fujimoto disease is a disorder that can mimic lymphoma and present with clinical and histopathological overlap with systemic lupus erythematosus in adolescent patients.</p><p><strong>Case report: </strong>A 15-year-old female patient presented with recurrent upper respiratory tract infections. Concomitantly, she developed morning arthralgia in the bilateral metacarpophalangeal joints and a photosensitive malar rash. Subsequently, she developed persistent intermittent fever, anorexia, joint limitation, and cervical and inguinal lymphadenopathy, associated with normocytic normochromic anemia. Complete blood count revealed leukopenia and progressive anemia. Bone marrow biopsy showed increased cellularity with erythroid hypoplasia and reactive megaloblastic changes. Immunohistochemical staining revealed reactive polyclonal lymphoid hyperplasia. During her hospitalization, oral ulcers, jaundice, a skin rash, and elevated transaminases and direct bilirubin were detected. She developed bilateral pleural effusion, acute respiratory failure, and required mechanical ventilation. Positive antinuclear antibodies were documented: 1:640 (AC-20 pattern), leading to a diagnosis of systemic lupus erythematosus. Treatment was initiated with high-dose corticosteroids, intravenous immunoglobulin, and cyclophosphamide for refractory lupus pneumonitis, with initial clinical improvement. She was transferred to a tertiary care hospital; however, she experienced progressive multisystem deterioration and died despite the treatment.</p><p><strong>Conclusions: </strong>Early recognition of the overlap between Kikuchi-Fujimoto disease and systemic lupus erythematosus is essential to avoid treatment delays and guide the timely prescription of immunosuppression in severe cases. Prolonged clinical surveillance and close follow-up are crucial for the timely detection of complications and to optimize patient prognosis.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"73 2","pages":"e195-e200"},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148428021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prebiotics and asthma: current insights and future directions from a bibliometric analysis.","authors":"A Farih Raharjo, Hamzah Haryo Prakoso, Andre Setiawan, Lisana Sidqi Aliya, Tika Tazkiya Tasnim","doi":"10.29262/ram.v73i2.1616","DOIUrl":"10.29262/ram.v73i2.1616","url":null,"abstract":"<p><strong>Background: </strong>Prebiotics have gained attention as a microbiome-modulating strategy in asthma because they may influence immune regulation through the gut-lung axis. However, evidence on prebiotics and asthma remains distributed across allergy, immunology, nutrition, microbiology, and respiratory medicine.</p><p><strong>Objectives: </strong>This study aimed to map global research trends, influential contributors, and thematic development in prebiotics-asthma research using bibliometric analysis.</p><p><strong>Methodology: </strong>This bibliometric study analyzed English-language articles and reviews indexed in Scopus. Prebiotic-related and synbiotic-related terms were combined using OR and then linked with asthma-related terms using AND. Eligible records were screened for relevance to prebiotics and asthma. Bibliometric analyses and visualizations were performed using Biblioshiny and VOSviewer to evaluate publication output, leading contributors, citation impact, keyword co-occurrence, and temporal research trends.</p><p><strong>Results: </strong>A total of 296 publications from 166 sources were included. The earliest eligible publication was published in 2002. Annual scientific production increased over time, with an annual growth rate of 13.66% and the highest output in 2024. Review articles outnumbered original articles. The United States was the leading contributor, followed by Australia, the Netherlands, Italy, and China. Keyword analysis identified three major domains: mechanistic and immunologic studies, early-life allergy prevention, and microbiota-focused modulation. Trend analysis showed a shift toward gut microbiome, short-chain fatty acids, immune dysregulation, and gut-lung axis.</p><p><strong>Conclusion: </strong>Prebiotics-asthma research is a relatively recent but steadily growing field with increasing emphasis on microbiome-mediated and mechanistic pathways. However, asthma-specific translational evidence remains limited, supporting the need for standardized clinical studies and integrative multi-omic approaches.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"73 2","pages":"e165-e177"},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148428046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of feeding regimen on the acquisition of immunological tolerance in mexican infants with IgE-mediated cow's milk protein allergy.","authors":"Hannia Bertha Matt Hernández, Virginia María González Pérez, Victor Soto Torres Septién","doi":"10.29262/ram.v73i2.1592","DOIUrl":"10.29262/ram.v73i2.1592","url":null,"abstract":"<p><strong>Objective: </strong>To compare the rate of tolerance acquisition in Mexican infants with IgE-mediated cow's milk protein allergy, fed according to three dietary regimens.</p><p><strong>Methods: </strong>A retrospective, observational cohort study was conducted on infants diagnosed with cow's milk protein allergy between 1 and 3 months of age, divided into three groups according to their feeding regimen: 1) exclusive breastfeeding with an elimination diet, 2) amino acid-based formula, and 3) hydrolyzed rice formula. Clinical characteristics, wheal size in skin prick tests against casein, alpha-lactalbumin, and beta-lactoglobulin, adherence to treatment, and coexisting allergic comorbidities were evaluated. Tolerance acquisition was determined by an open oral challenge test with whole milk after 12 months on an elimination diet. Comparative analyses and multivariate logistic regression were performed to identify associated factors.</p><p><strong>Results: </strong>285 infants were selected and assigned to one of three study groups (n = 95 per group). 62.1% achieved clinical tolerance at the end of the follow-up period. The highest proportion was observed in the exclusive breastfeeding group (78.9%), followed by the amino acid-based formula group (68.4%) and the hydrolyzed rice formula group (65.3%), with no statistically significant differences between the regimens (p = 0.094). Adherence to the dietary treatment was significantly associated with the acquisition of tolerance in the multivariate model, while allergic comorbidities were associated with a lower probability of clinical cure.</p><p><strong>Conclusions: </strong>The elimination diet is associated with the acquisition of tolerance in a considerable proportion of infants with IgE-mediated cow's milk protein allergy. Although no superiority was identified among the dietary regimens, the findings suggest that adherence to treatment plays a determining role in clinical outcomes and should be considered a central component in the management of the disease.</p>","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"73 2","pages":"e129-e136"},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148427901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond scientific advances: delays, disparities, and opportunities in hereditary angioedema care across Latin America.","authors":"Ricardo Dario Zwiener","doi":"10.29262/ram.v73i2.1617","DOIUrl":"https://doi.org/10.29262/ram.v73i2.1617","url":null,"abstract":"","PeriodicalId":101421,"journal":{"name":"Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)","volume":"73 2","pages":"e206-e208"},"PeriodicalIF":0.0,"publicationDate":"2026-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148427961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}