International journal of heart failure最新文献_第3页

The Korean Society of Heart Failure: Breaking Barriers, Bridging Solutions Together! 韩国心力衰竭协会：打破障碍，共同解决问题！

International journal of heart failure Pub Date : 2023-10-18 eCollection Date: 2023-10-01 DOI: 10.36628/ijhf.2023.0045

Seok Min Kang

引用次数: 0

C-Reactive Protein Can Predict Outcomes in Patients With Takotsubo Syndrome. C 反应蛋白可预测塔克次氏综合征患者的预后。

International journal of heart failure Pub Date : 2023-10-10 eCollection Date: 2024-01-01 DOI: 10.36628/ijhf.2023.0033

Gassan Moady, BateL Yelin, Rania Sweid, Shaul Atar

{"title":"C-Reactive Protein Can Predict Outcomes in Patients With Takotsubo Syndrome.","authors":"Gassan Moady, BateL Yelin, Rania Sweid, Shaul Atar","doi":"10.36628/ijhf.2023.0033","DOIUrl":"https://doi.org/10.36628/ijhf.2023.0033","url":null,"abstract":"Background and objectives: Takotsubo syndrome (TTS) is a form of reversible cardiomyopathy often preceded by mental or physical stressors and predominantly affects elderly women. Several cardiac and inflammatory biomarkers are involved in the pathogenesis of the disease. We aimed to investigate the correlation of C-reactive protein (CRP) level with left ventricular ejection fraction (LVEF) and clinical outcomes in patients with TTS.Methods: The study included patients with discharge-diagnosis of Takotsubo through 2017-2022 from the cardiology department. Demographic, laboratory, echocardiographic, and clinical outcomes were retrospectively obtained. We investigated the relation between CRP and LVEF, length of stay (LOS), in-hospital complications, and recurrence.Results: A total of 86 patients (93% female, mean age 68.8±12.3 years) were included in the study. The median CRP level was 17.4 (interquartile range [IQR], 6.1-40.1) mg/L, and the mean LVEF was 41.5%, (IQR, 38-50%). Complications occurred in 24 (27.9%) of the patients, and the median LOS was 3 (IQR, 3-5) days. The level of CRP was associated with lower LVEF (r=-0.39, p<0.001), longer hospital stay (r=0.25, p=0.021), and recurrence. There was no correlation between CRP and in-hospital complications. In multivariate logistic regression, poor LVEF was associated with TTS recurrence (odds ratio, 1.22; 95% confidence interval, 1.08-1.37; p=0.001). Using linear regression, only CRP was correlated with longer LOS and lower LVEF (p<0.001).Conclusions: Among patients hospitalized with TTS, CRP level was associated with poor LVEF and prolonged hospital stay but not with in-hospital complications. Poor LVEF was also associated with TTS recurrence.","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827700/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139673986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elucidating the Interplay: Exploring the Impact of Acute Heart Failure on Aspiration Pneumonia Hospitalizations. 阐明相互作用：探讨急性心力衰竭对吸入性肺炎住院的影响。

International journal of heart failure Pub Date : 2023-09-20 eCollection Date: 2023-10-01 DOI: 10.36628/ijhf.2023.0049

Min-Seok Kim

引用次数: 0

Differences in Leukocyte Transcriptomes of Morbidly Obese Patients With High Output Heart Failure: A Pilot Study. 高输出量心力衰竭病态肥胖患者白细胞转录组的差异：一项初步研究。

International journal of heart failure Pub Date : 2023-09-05 eCollection Date: 2023-10-01 DOI: 10.36628/ijhf.2023.0027

Samantha A Cintron, Janet Pierce, Mihaela E Sardiu, Diane Mahoney, Jill Peltzer, Bhanu Gupta, Qiuhua Shen

{"title":"Differences in Leukocyte Transcriptomes of Morbidly Obese Patients With High Output Heart Failure: A Pilot Study.","authors":"Samantha A Cintron, Janet Pierce, Mihaela E Sardiu, Diane Mahoney, Jill Peltzer, Bhanu Gupta, Qiuhua Shen","doi":"10.36628/ijhf.2023.0027","DOIUrl":"10.36628/ijhf.2023.0027","url":null,"abstract":"Background and objectives: Heart failure is characterized by alterations of gene expression that provide insight into the underlying pathophysiologic mechanisms. However, obesity-related high output heart failure (HOHF) is a specific phenotype of heart failure that has not been studied using gene expression. Our aim in this study was to examine the variances in leukocyte transcriptomes of morbidly obese patients with HOHF.Methods: In this cross-sectional study, we applied stranded total RNA-sequencing to six patients with morbid obesity and HOHF and 6 patients with morbid obesity and non-HOHF. Differential gene expression was calculated, and Ingenuity Pathway Analysis software was used to interpret the canonical pathways, functional changes, upstream regulators, and networks in these patients.Results: We found in patients with HOHF that there were 116 differentially expressed genes with upregulation of 114 genes and downregulation of 2 genes. The differentially expressed genes were involved with cell proliferation, mitochondrial function, erythropoiesis, erythrocyte stability, and apoptosis. The top upregulated canonical pathways associated with differentially expressed genes were autophagy, adenosine monophosphate-activated protein kinase signaling, and senescence pathways. We identified GATA binding protein 1 as an upstream regulator and nuclear factor kappa-light-chain-enhancer of activated B cells associated network.Conclusions: We are the first to report the differential gene expression in patients with obesity-related HOHF and reveal the various pathophysiologic mechanisms underlying the disease. Further research is needed to determine the role of cellular function and maintenance, inflammation, and iron homeostasis in obesity-related HOHF.","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10625880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71490976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Direct Oral Anticoagulants in Patients With Cardiac Amyloidosis: A Systematic Review and Meta-Analysis 心脏淀粉样变性患者直接口服抗凝剂:系统回顾和荟萃分析

International journal of heart failure Pub Date : 2023-01-01 DOI: 10.36628/ijhf.2023.0031

Spencer C. Lacy, Menhel Kinno, Cara Joyce, Mingxi D. Yu

引用次数: 0

Adverse Events in Total Artificial Heart for End-Stage Heart Failure: Insight From the Food and Drug Administration Manufacturer and User Facility Device Experience (MAUDE) 全人工心脏治疗终末期心力衰竭的不良事件:来自食品和药物管理局、制造商和用户设施设备体验(MAUDE)的见解

International journal of heart failure Pub Date : 2023-01-01 DOI: 10.36628/ijhf.2023.0020

Min Choon Tan, Yong Hao Yeo, Jia Wei Tham, Jian Liang Tan, Hee Kong Fong, Bryan E-Xin Tan, Kwan S Lee, Justin Z Lee

引用次数: 0

Home Bioelectrical Impedance Analysis Management System in Patients With Heart Failure: Rationale and Study Design 心力衰竭患者的家庭生物电阻抗分析管理系统:理论基础和研究设计

International journal of heart failure Pub Date : 2023-01-01 DOI: 10.36628/ijhf.2023.0018

Min Gyu Kong, Inki Moon, Hye-Sun Seo, Jon Suh, Jah Yeon Choi, Jin Oh Na, Eung Ju Kim

引用次数: 0