International journal of heart failure最新文献

{"title":"Exercise Training in HFpEF: Functional Improvement Beyond Resting Diastolic Indices.","authors":"Moon-Seung Soh","doi":"10.36628/ijhf.2026.0089","DOIUrl":"10.36628/ijhf.2026.0089","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"8 3","pages":"253-255"},"PeriodicalIF":0.0,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circadian Blood Pressure at Hospital Discharge: A Physiological Window Into the Vulnerable Phase of Heart Failure.","authors":"Dae Young Cheon","doi":"10.36628/ijhf.2026.0079","DOIUrl":"10.36628/ijhf.2026.0079","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"8 3","pages":"228-230"},"PeriodicalIF":0.0,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447182/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Two-Minute Step Test in Heart Failure: A Practical Step Forward, Pending Validation.","authors":"Dong Hoon Lee","doi":"10.36628/ijhf.2026.0088","DOIUrl":"10.36628/ijhf.2026.0088","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"8 3","pages":"239-240"},"PeriodicalIF":0.0,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447185/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Value of Ambulatory Blood Pressure Monitoring in Patients Admitted With Acute Decompensated Heart Failure: A Prospective Observational Study From a Tertiary Referral Centre.","authors":"Tanmay Boob, Pooja Vyas, Kewal Kanabar, Krutika Patel, Ravina Modi, Mohit Khare, Iva Patel","doi":"10.36628/ijhf.2025.0090","DOIUrl":"10.36628/ijhf.2025.0090","url":null,"abstract":"<p><strong>Background and objectives: </strong>Heart failure (HF) remains a major cause of morbidity and frequent readmissions in India. Ambulatory blood pressure monitoring (ABPM) offers dynamic evaluation of blood pressure (BP) patterns, BP variability and morning blood pressure surge (MBPS) which may provide prognostic value in patients with acute decompensated heart failure (ADHF).</p><p><strong>Methods: </strong>A prospective observational study enrolling 300 patients admitted with ADHF. After stabilization and prior to discharge, all patients underwent ABPM and were categorized based on dipper patterns. Clinical outcomes, including mortality and re-hospitalization at 3 months, were assessed. Survival analyses were performed using Kaplan-Meier curves and multivariable Cox regression.</p><p><strong>Results: </strong>The mean age of the cohort was 60.2 years; 68% were male. Most patients had HF with reduced ejection fraction (84%), and 57% were hypertensive. Dipper patterns were distributed: normal dipper 51%, non-dipper 36%, reverse dipper 11%, and extreme dipper 2%. At 3 months, mortality was 5.3% and re-hospitalization in 44% of patients. Kaplan-Meier analysis revealed increased mortality in reverse dippers, highest average real variability percentile, and low/high MBPS groups (p<0.0001). Multivariable Cox regression identified extreme dipper (hazard ratio [HR], 9.28; 95% confidence interval [CI], 1.85-46.49; p=0.007), reverse dipper (HR, 7.53; 95% CI, 2.47-22.10; p=0.01), low systolic BP (HR, 3.70; 95% CI, 1.22-11.22; p=0.02) associated to mortality.</p><p><strong>Conclusions: </strong>ABPM is a practical tool for risk stratification in HF. Abnormal nocturnal BP dipper patterns and increased BP variability were associated with increased adverse short-term outcomes in ADHF. Discharge ABPM may aid early risk stratification, while other circadian BP abnormalities primarily reflect disease severity rather than independent risk.</p>","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"8 3","pages":"219-227"},"PeriodicalIF":0.0,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Reflex to Reason: Does New-Onset Heart Failure Warrant a Routine Ischemic Evaluation?","authors":"Minju Han, Jeehoon Kang","doi":"10.36628/ijhf.2026.0081","DOIUrl":"10.36628/ijhf.2026.0081","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"8 3","pages":"216-218"},"PeriodicalIF":0.0,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447181/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TriageHF^® in Real-World Practice: The Limits of \"No News Is Good News\".","authors":"Masataka Kawana","doi":"10.36628/ijhf.2026.0083","DOIUrl":"10.36628/ijhf.2026.0083","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"8 3","pages":"263-265"},"PeriodicalIF":0.0,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447184/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rural-Urban Disparities in Heart Failure and Liver Cirrhosis Hospitalizations: A National Inpatient Sample Database Analysis (2016-2022).","authors":"Farah Yasmin, Yusra Mashkoor, Maryam Shahryar, Ahmad Barbour, Muhammad Sohaib Asghar, M Chadi Alraies","doi":"10.36628/ijhf.2025.0086","DOIUrl":"10.36628/ijhf.2025.0086","url":null,"abstract":"<p><p>Heart failure and cirrhosis interplay predisposes patients to increased inpatient morbidity, acute decompensation, renal injury, infection, procedural complications, prolonged hospitalizations, and healthcare costs. In this retrospective observational study, we analyzed data from the Nationwide Inpatient Sample spanning 2016 to 2022 to assess rural-urban disparities and temporal trends in adult patients hospitalized with concurrent HF and liver cirrhosis in the U.S. Validated International Classification of Diseases, 10th Revision codes were used to identify these patients. A total of 498,539 hospitalizations (weighted >2.49 million) met inclusion criteria, of which 14.9% occurred in non-metropolitan hospitals and 85.1% in metropolitan hospitals. In-hospital mortality was higher in rural settings (8.0% vs. 7.3%), with slightly longer hospital stays in urban settings that incurred a greater financial burden, with higher inflation-adjusted costs ($24,026 vs. $20,948). These results were consistent with propensity-matching. The study concludes that strategies to improve regional healthcare access and equity in complex multisystem disease management are needed.</p>","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"8 3","pages":"266-270"},"PeriodicalIF":0.0,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert Consensus and Clinical Pathway Recommendations for Transthyretin Amyloid Cardiomyopathy in Malaysia.","authors":"Mohd Rahal Yusoff, Raja Ezman Farid Raja Shariff, Choon Keong Tee, Kee Wei Lee, Nor Hanim Mohd Amin, Lean Seng Chen, Thurston Erng, Kavita Arumugam, Siti Nooraein Yaser, Jerome Tsen Chuen Tan, Suhashini Ganapaty, Roslina Omar, Thuhairah Abdul Rahman, Lock Hock Ngu, Soon Chai Low, Nur Shafini Che Rahim, Yen Yee Oon","doi":"10.36628/ijhf.2026.0012","DOIUrl":"10.36628/ijhf.2026.0012","url":null,"abstract":"<p><p>Transthyretin amyloid cardiomyopathy (ATTR-CM) is a progressive, life-threatening condition that remains under-recognised in Malaysia. Although disease-modifying therapies are available, their high cost and limited accessibility contribute to delays in diagnosis, compounded by gaps in clinical awareness, differences in diagnostic tool availability and disparities in healthcare resources. While international guidelines offer a comprehensive framework for diagnosing and managing ATTR-CM, local adaptation is essential to ensure their relevance and feasibility within the Malaysian healthcare system. This expert consensus provides practical, locally relevant recommendations to assist Malaysian clinicians in the timely identification and management of ATTR-CM. A multidisciplinary panel of clinicians from cardiology, haematology, nuclear medicine and other related specialties convened to develop tailored recommendations for national practice, drawing on international guidance, current evidence and local clinical practices. The guidance outlines key clinical features to raise early suspicion, proposes a diagnostic algorithm adaptable to different levels of care and offers recommendations on appropriate use of diagnostic tests-including imaging, laboratory investigations, tissue biopsy, and genetic testing when indicated-while emphasising the distinction between ATTR-CM and amyloid light chain amyloidosis, optimising non-invasive diagnostic approaches and fostering multidisciplinary collaboration across the care continuum. These consensus recommendations aim to enhance diagnostic accuracy, reduce variability in clinical practice and support earlier identification of ATTR-CM. By bridging global standards with local healthcare practices, this guidance equips clinicians to deliver timely, effective care for an underdiagnosed and often overlooked condition.</p>","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"8 3","pages":"193-206"},"PeriodicalIF":0.0,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-World Diagnostic Performance for Heart Failure Events of TriageHF^® Algorithm.","authors":"Mariana Pereira Santos, Sérgio Campos, Catarina Gomes, Maria Trepa, Bruno Bragança, Maria Isilda Oliveira, Mariana Rajão, Bruno Delgado, Sara Fernandes, Sónia Magalhães, Maria João Sousa, António Pinheiro Vieira, Hipólito Reis, André Luz, Mário Santos","doi":"10.36628/ijhf.2026.0016","DOIUrl":"10.36628/ijhf.2026.0016","url":null,"abstract":"<p><strong>Background and objectives: </strong>Heart failure (HF) remote monitoring programs collect HF-related parameters from cardiac implantable electronic devices, enabling early interventions and reducing healthcare burdens. This study aimed to characterize HF patients, alert burden, and the association between TriageHF^® alerts and HF decompensation.</p><p><strong>Methods: </strong>This retrospective observational study, 134 patients enrolled in an outpatient remote monitoring HF program with the TriageHF^® algorithm between February 2022 and July 2023. Data on alert frequency, data driving the alerts, and alert duration were collected. Clinical outcomes included unplanned emergency room visits, HF hospitalizations, all-cause death, and a composite of these events.</p><p><strong>Results: </strong>Over a median follow-up of 1.7 years, 77 individual high-risk alerts (0.44 alerts per patient-year) occurred. HF patients who eventually had an alert were similar to those without any alerts, except for the increased prevalence of chronic kidney disease, stroke history and use of furosemide. The event rate was 1.1% per month, and the alert state was 3.2% of the total follow-up duration. Six events occurred during high-risk days (event rate of 7.9% per month vs. 0.8% per month during standard-risk days). TriageHF^® alerts demonstrated a sensitivity of 35%, a specificity of 71%, a positive predictive value of 25%, and a negative predictive value of 80% for predicting a composite of HF hospitalization, unplanned ER visits, and death.</p><p><strong>Conclusions: </strong>The TriageHF^® algorithm identified periods with a higher incidence of HF-related adverse events, supporting efficient resource allocation. The low alert burden also supports feasibility in resource-limited settings.</p>","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"8 3","pages":"256-262"},"PeriodicalIF":0.0,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447195/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Exercise Training Enhance the Functional Capacity and Diastolic Function in Heart Failure With Preserved Ejection Fraction? A Systematic Review and Meta-analysis in the East Asian Population.","authors":"Dwita Rian Desandri, Faqrizal Ria Qhabibi, Tristan Ramcharan, Dimitra Nikoletou, Michael Papadakis","doi":"10.36628/ijhf.2026.0003","DOIUrl":"10.36628/ijhf.2026.0003","url":null,"abstract":"<p><strong>Background and objectives: </strong>Recent research indicated that the physiological mechanisms in heart failure with preserved ejection fraction (HFpEF) patients across various ethnicities/races exhibited distinct findings. Published research predominantly derives from Western populations and lacks evidence concerning the effects of exercise training on East Asian individuals. This study aimed to examine the impact of exercise training interventions on peak oxygen consumption (VO₂) and diastolic function in the East Asian population with HFpEF.</p><p><strong>Methods: </strong>Articles were retrieved utilizing Medical Subject Headings phrases across 3 databases. Our research, documented in the PROSPERO database, encompassed trials and prospective studies that investigated peak VO₂ and diastolic function in East Asian patients with HFpEF who participated in an exercise training program. The random-effects model was utilized to evaluate the aggregated effect, represented as a mean difference (MD). The leave-one-out strategy was utilized to exclude research to evaluate the robustness of the results.</p><p><strong>Results: </strong>Six studies were examined; however, only 4 were appropriate for quantitative analysis. Exercise training for HFpEF patients successfully elevated the average peak VO₂ (MD, 1.99; 95% confidence interval [CI], 0.57, 3.40; p=0.006; I²=57%). However, there was no alteration in diastolic function (E/A [MD, -0.17; 95% CI, -0.57, 0.23; p=0.41; I²=89%] and E/e' [MD, -0.92; 95% CI, -3.58, 1.75; p=0.50; I²=43%]) after exercise intervention.</p><p><strong>Conclusions: </strong>Exercise training for a minimum of 12 weeks, irrespective of the exercise modality, is associated with improvements in exercise capacity among the selected East Asian patients, particularly in peak VO₂, while observing minimal influence on diastolic function.</p><p><strong>Trial registration: </strong>International Prospective Register of Systematic Reviews (PROSPERO) Identifier: CRD420251040914.</p>","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"8 3","pages":"241-252"},"PeriodicalIF":0.0,"publicationDate":"2026-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13447192/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}