{"title":"The Impact of the Novel Sodium-Dependent Glucose Cotransporter 2 Inhibitor, Enavogliflozin, on Cardiac Reverse Remodeling in Heart Failure Patients With Type 2 Diabetes Mellitus: A Case Series.","authors":"Taeil Yang, Youngwoo Jang, Wook-Jin Chung","doi":"10.36628/ijhf.2024.0018","DOIUrl":"https://doi.org/10.36628/ijhf.2024.0018","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"6 4","pages":"176-178"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538723/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adequacy of Ambulatory Hemodynamic Assessments for Reducing All-Cause Mortality in Individuals With Heart Failure.","authors":"Reza Tabrizchi","doi":"10.36628/ijhf.2024.0021","DOIUrl":"https://doi.org/10.36628/ijhf.2024.0021","url":null,"abstract":"<p><p>Heart failure (HF) as a syndrome which is <i>normally</i> associated with significant reduction of cardiac output has evolved to include conditions such those of moderate and preserved ejection fraction. While the prevalence of HF in the population is increasing, it is not HF with reduced ejection fraction that is driving the trajectory upward for mortality. There is some evidence to suggest that a better understanding of the pathophysiology, novel pharmacological strategies, devices, as well as remote monitoring of the hemodynamics seem to account for a reduction in the cardiovascular mortality and re-hospitalization in some cohorts with HF. However, the all-cause mortality associated with HF has not been reduced significantly by the current interventions. To explore the potential approaches needed for the strategies and avenues to reduce all-cause mortality in patients with HF, it would be helpful to evaluate the evidence in the literature directed at the care of patients with chronic/acute decompensated HF. It is evident that ambulatory measurements of pressures and volume are pivotal in a better management of HF but unless the interventions extend to an improvement in the renal function, the chances of reducing all-cause mortality seems modest. Therefore, future directions of interventions must not only be directed at close monitoring of pressures and volume simultaneously in HF patients but also at improving renal function. Moreover, it is clear that venous congestion plays a detrimental role in the deterioration of renal function and until measures are in place to reduce it, all-cause mortality will not decrease.</p>","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"6 4","pages":"149-158"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jae-Hyeong Park, Mijoo Kim, Jin Joo Park, Jun-Bean Park, Goo-Yeong Cho
{"title":"Prognostic Role of RVGLS/PASP Ratio, a New Echocardiographic Parameter of the Right Ventricle-Pulmonary Artery Coupling, in Patients With Acute Heart Failure.","authors":"Jae-Hyeong Park, Mijoo Kim, Jin Joo Park, Jun-Bean Park, Goo-Yeong Cho","doi":"10.36628/ijhf.2024.0048","DOIUrl":"https://doi.org/10.36628/ijhf.2024.0048","url":null,"abstract":"<p><strong>Background and objectives: </strong>Few studies have addressed the predictive implications of right ventricular (RV) and pulmonary arterial (PA) coupling as assessed by echocardiography in patients with acute heart failure (AHF). This study aimed to ascertain the prognostic importance of RV-PA coupling in AHF cases and discern any divergence in its prognostic efficacy based on different heart failure (HF) phenotypes.</p><p><strong>Methods: </strong>We evaluated RV-PA coupling by measuring the ratio of right ventricular global longitudinal strain (RVGLS) to pulmonary arterial systolic pressure (PASP), termed the RVGLS/PASP ratio, and assessed its prognostic role using the STrain for Risk Assessment and Therapeutic Strategies in Patients with Acute Heart Failure registry.</p><p><strong>Results: </strong>From an AHF registry of 4312 patients, we analyzed the RVGLS/PASP ratio in 2,865 patients (1,449 men; age, 71.1±13.5 years). At a median follow-up of 35.0 months, 1,199 (41.8%) patients died. Remarkably, PASP (hazard ratio [HR], 1.012; p<0.001), RVGLS (HR, 1.019; p<0.001), and the RVGLS/PASP ratio (HR, 2.426; p<0.001) were statistically significant predictors of all-cause mortality in the univariate analysis. The RVGLS/PASP ratio was a significant predictor of all-cause mortality in all the HF phenotypes, including HF with reduced ejection fraction (HR, 2.124; p=0.002), HF with mildly reduced ejection fraction (HR, 2.733; p=0.021), and HF with preserved ejection fraction (HR, 2.134; p=0.006). Multivariate analysis after adjusting for clinical and echocardiographic variables revealed that the RVGLS/PASP ratio ≤0.32 was associated with a 36% increase in all-cause mortality (HR, 1.365; p<0.001).</p><p><strong>Conclusions: </strong>Impaired RV-PA coupling, defined as an RVGLS/PASP ratio (≤0.32) was associated with an increased risk of mortality in patients with AHF across all HF phenotypes.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov Identifier: NCT03513653.</p>","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"6 4","pages":"165-173"},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sang Gune K Yoo, Mohammed O Ahmed, Nancy K Sweitzer
{"title":"Current and Future of Heart Failure Care in Asia.","authors":"Sang Gune K Yoo, Mohammed O Ahmed, Nancy K Sweitzer","doi":"10.36628/ijhf.2024.0033","DOIUrl":"https://doi.org/10.36628/ijhf.2024.0033","url":null,"abstract":"<p><p>Heart failure (HF) is a significant global health concern, particularly in Asia, where over half of the world's population resides. Despite advances in treatment, the burden of HF is expected to rise in the region due to the aging population and an increase in non-communicable diseases associated with HF risk. This narrative review examines the current state of HF in Asia, highlighting differences in treatment utilization, underrepresentation of Asian individuals in clinical trials, emerging therapies, and implementation strategies, including the potential use of polypills and the need for expanded HF training opportunities for healthcare providers.</p>","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"6 4","pages":"141-148"},"PeriodicalIF":0.0,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Elevating Right Ventricular Assessment: The Transformative Prognostic Power of RVGLS/PASP Ratio in Acute Heart Failure.","authors":"SungA Bae","doi":"10.36628/ijhf.2024.0058","DOIUrl":"https://doi.org/10.36628/ijhf.2024.0058","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"6 4","pages":"174-175"},"PeriodicalIF":0.0,"publicationDate":"2024-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538724/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Next Chapter of <i>International Journal of Heart Failure</i>.","authors":"Jin Joo Park","doi":"10.36628/ijhf.2024.0054","DOIUrl":"https://doi.org/10.36628/ijhf.2024.0054","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"6 4","pages":"159-160"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Min-Seok Kim, Jaewon Oh, Jin-Oh Choi, Seok-Min Kang
{"title":"Trends of Left Ventricular Assist Device Implantation and Heart Transplantation in Korea.","authors":"Min-Seok Kim, Jaewon Oh, Jin-Oh Choi, Seok-Min Kang","doi":"10.36628/ijhf.2024.0024","DOIUrl":"https://doi.org/10.36628/ijhf.2024.0024","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"6 4","pages":"161-164"},"PeriodicalIF":0.0,"publicationDate":"2024-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11538725/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Heart Failure With Preserved Ejection Fraction and Atrial Fibrillation: Are Beta-Blockers Still Relevant?","authors":"Junho Hyun","doi":"10.36628/ijhf.2024.0038","DOIUrl":"10.36628/ijhf.2024.0038","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"6 3","pages":"127-128"},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11284336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jah Yeon Choi, Mi-Na Kim, Seongwoo Han, Sunki Lee, Myung Soo Park, Min Gyu Kong, Sung-Hea Kim, Yong-Hyun Kim, Sang-Ho Jo, Sungeun Kim, Seonghoon Choi, Jinsung Jeon, Jieun Lee, Byambakhand Battumur, Seong-Mi Park, Eung Ju Kim
{"title":"Rationale, Design, and Interim Observations of the Steady Movement With Innovating Leadership for Heart Failure (SMILE HF) Registry: A Multicenter Prospective Cohort Registry for Patients With Acute Heart Failure.","authors":"Jah Yeon Choi, Mi-Na Kim, Seongwoo Han, Sunki Lee, Myung Soo Park, Min Gyu Kong, Sung-Hea Kim, Yong-Hyun Kim, Sang-Ho Jo, Sungeun Kim, Seonghoon Choi, Jinsung Jeon, Jieun Lee, Byambakhand Battumur, Seong-Mi Park, Eung Ju Kim","doi":"10.36628/ijhf.2024.0014","DOIUrl":"10.36628/ijhf.2024.0014","url":null,"abstract":"<p><strong>Background and objectives: </strong>Heart failure (HF) is a leading cause of hospitalization and death worldwide. The Steady Movement with Innovating Leadership for Heart Failure (SMILE HF) aims to evaluate the clinical characteristics, management, hospital course, and long-term outcomes of patients hospitalized for acute HF in South Korea.</p><p><strong>Methods: </strong>This prospective, observational multicenter cohort study was conducted on consecutive patients hospitalized for acute HF in nine university hospitals since September 2019. Enrolment of 2000 patients should be completed in 2024, and follow-up is planned through 2025.</p><p><strong>Results: </strong>Interim analysis of 1,052 consecutive patients was performed to understand the baseline characteristics. The mean age was 69±15 years; 57.6% were male. The mean left ventricular ejection fraction was 39±15%. The prevalences of HF with reduced ejection fraction, HF with mildly reduced ejection fraction, and HF with preserved ejection fraction were 50.9%, 15.3%, and 29.2%. Ischemic cardiomyopathy (CMP) was the most common etiology (32%), followed by tachycardia-induced CMP (12.8%) and idiopathic dilated CMP (9.5%). The prescription rate of angiotensin-converting enzyme inhibitor/angiotensin receptor blockers/angiotensin receptor/neprilysin inhibitor, beta-blockers, spironolactone, and sodium-glucose cotransporter-2 inhibitors at discharge were 76.8%, 66.5%, 50.0%, and 17.5%, respectively. The post-discharge 90-day mortality and readmission rates due to HF aggravation were 2.0% and 6.4%, respectively. Our analysis reveals the current state of acute HF in South Korea.</p><p><strong>Conclusions: </strong>Our interim analysis provides valuable insights into the clinical characteristics, management, and early outcomes of acute HF patients in South Korea, highlighting the current state and treatment patterns in this population.</p>","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"6 3","pages":"129-136"},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11284335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"President's Message: 4 Pillars of Korean Society of Heart Failure.","authors":"Byung-Su Yoo","doi":"10.36628/ijhf.2024.0031","DOIUrl":"10.36628/ijhf.2024.0031","url":null,"abstract":"","PeriodicalId":101410,"journal":{"name":"International journal of heart failure","volume":"6 3","pages":"117-118"},"PeriodicalIF":0.0,"publicationDate":"2024-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11284338/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141857553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}