Korean journal of ophthalmology : KJO最新文献

{"title":"Increased Risk of OMDI-Induced Cystoid Macular Edema Following Pars Plana Vitrectomy.","authors":"Yao-Yi Kuo, Cheng-Kuo Cheng","doi":"10.3341/kjo.2025.0056","DOIUrl":"https://doi.org/10.3341/kjo.2025.0056","url":null,"abstract":"","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144824457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Familial Exudative Vitreoretinopathy in a patient with Jacobsen Syndrome.","authors":"Jiu Lee, Sungsoon Hwang, Sang Jin Kim","doi":"10.3341/kjo.2025.0022","DOIUrl":"https://doi.org/10.3341/kjo.2025.0022","url":null,"abstract":"","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144791222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Persistent Corneal Epithelial Defects Associated with Afatinib Therapy in a Patient with Non-Small Cell Lung Cancer: A Case Report.","authors":"Myung Ho Cho, Jae Hyun Kim, Ji Hoon Ban, Yeong Chae Jo, Jong Soo Lee","doi":"10.3341/kjo.2025.0089","DOIUrl":"https://doi.org/10.3341/kjo.2025.0089","url":null,"abstract":"","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144791224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcomes and Predictive Factors of Intraoperative Miosis During Femtosecond Laser-Assisted Cataract Surgery: Results from the First 300 Cases.","authors":"Bu Ki Kim, Young Taek Chung","doi":"10.3341/kjo.2025.0064","DOIUrl":"https://doi.org/10.3341/kjo.2025.0064","url":null,"abstract":"<p><strong>Purpose: </strong>To compare clinical outcomes between patients with and without intraoperative miosis during femtosecond laser-assisted cataract surgery (FLACS) and to identify risk factors for intraoperative miosis during the initial learning curve in the surgeon's first 300 consecutive cases.</p><p><strong>Methods: </strong>This retrospective cohort study included the first 300 consecutive FLACS cases performed by a single surgeon at a single center. A 5.0 mm capsulotomy was created in all cases using a femtosecond laser. Eyes were divided into 2 groups based on pupil diameter after femtosecond laser treatment: miosis group (<5 mm) and mydriasis group (≥5 mm). Clinical outcomes at 3 months were compared. Perioperative variables were analyzed to identify factors associated with intraoperative miosis.</p><p><strong>Results: </strong>Of the 300 eyes, 52 (17.3%) were in the miosis group and 248 (82.7%) in the mydriasis group. The miosis group had significantly smaller preoperative pupil diameter (P = 0.002), narrower capsulotomy-pupil margin distance (P = 0.002), longer vacuum duration (P < 0.001), longer phacoemulsification time (P = 0.005), and more frequent multiple docking attempts (P = 0.009). The first 150 cases had a higher incidence of multiple docking attempts (P < 0.001) and miosis (P < 0.001) compared to the second 150 cases. At 3 months, the mean corrected distance visual acuity was -0.01 ± 0.03 and 0.00 ± 0.04 in the miosis and mydriasis groups, respectively (P = 0.890), with no significant differences observed in specular microscopy outcomes. No mechanical expanders were used in any case, and no intraoperative complications occurred in either group.</p><p><strong>Conclusion: </strong>Small preoperative pupil diameter, narrow capsulotomy-pupil margin distance, prolonged vacuum duration, multiple docking, and the surgeon's initial learning curve were associated with intraoperative miosis during FLACS. Although phacoemulsification time was prolonged, it did not lead to a higher rate of intraoperative complications or adversely affect postoperative clinical outcomes.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144791223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling Active Surge Mitigation (ASM) Actuation: Optimizing Phacoemulsification With Active Sentry Handpiece.","authors":"Kuzmanović Elabjer Biljana, Štrbac Tea, Ćubela Iva, Rak Benedict, Martinčević Dora, Bušić Mladen, Bjeloš Mirjana","doi":"10.3341/kjo.2025.0072","DOIUrl":"https://doi.org/10.3341/kjo.2025.0072","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study is to determine which demographic and biometric factors, lens hardness, complications such as PEX and IFIS, and intraoperative metrics have the greatest influence on Active Surge Mitigation (ASM) actuation during phacoemulsification using the Centurion® Vision System with the ACTIVE SENTRY® Handpiece.</p><p><strong>Methods: </strong>The preoperative analysis considered age, gender, biometric data (obtained using the Zeiss IOL Master 700 and Oculus Pentacam), and lens hardness according to the Lens Opacification Classification System (LOCS III). Intraoperative Floppy Iris Syndrome (IFIS) and Pseudoexfoliation Syndrome (PEX) were also assessed. Intraoperative metrics during phacoemulsification included total case time, cumulative dissipated energy (CDE), total ultrasound time (U/S time), and the number of active surge mitigation (ASM) actuations.</p><p><strong>Results: </strong>Significant positive correlations were found between ASM and both LOCS (P=0.001) and age (P=0.017), albeit a significant negative correlation was observed with anterior chamber depth (ACD) (P=0.005). No significant differences in the number of ASM actuations were observed between genders or in patients with PEX or IFIS. In multivariate analysis, an ASM ≥ 1 significantly predicted higher LOCS (OR 1.79, 95% CI 1.04-2.95), whereas greater ACD reduced this likelihood (OR 0.311, 95% CI 0.100-0.960).</p><p><strong>Conclusions: </strong>ASM actuation is more frequent with advanced lens hardness and old age, while a deep anterior chamber reduces actuations compared to a shallow one. Lens hardness affects ASM more than anterior chamber depth, and no significant correlation was found between PEX, IFIS, and ASM.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144791234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Netarsudil-associated Reticular Bullous Corneal Epithelial Edema in a Bullous Keratopathy Patient with Glaucoma: A Case Report.","authors":"Hyun Woo Kim, Sam Seo, Sang Hee Lee, Kyoo Won Lee, Chong Eun Lee","doi":"10.3341/kjo.2025.0043","DOIUrl":"10.3341/kjo.2025.0043","url":null,"abstract":"","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"379-381"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evidence-based Nomenclature for Classification, Diagnosis, and Management of Infantile Exotropia.","authors":"Seung-Hyun Kim, Soo Hyun Kim, Daniel Jinhag Baik","doi":"10.3341/kjo.2025.0042","DOIUrl":"10.3341/kjo.2025.0042","url":null,"abstract":"<p><p>Despite extensive research on clinical characteristics, patient management, and surgical outcomes of intermittent exotropia, there remains significant confusion regarding the nomenclature system for infantile exotropia, which develops before 12 months of age. Additionally, there still is a controversy over whether infantile exotropia represents the phenotypic counterpart of infantile esotropia or early-onset intermittent exotropia. In this article, we critically review the previous nomenclature systems and propose some modifications to the current classifications of infantile exotropia. These include three diagnostic categories: primary infantile exotropia, early-onset intermittent exotropia, and secondary infantile exotropia. Stereopsis is valuable for differentiation between primary infantile exotropia and early-onset intermittent exotropia. However, further research is needed for more precise descriptions of their clinical features, optimal surgical timing, and proper management.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"369-375"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Six-Month Outcomes of Accelerated Corneal Cross-Linking with a Total Dose of 7.2 J/cm2 Using Dextran-Free Riboflavin.","authors":"Mustafa Turunç, Ahmet Özdemir, Ertuğrul Can","doi":"10.3341/kjo.2025.0063","DOIUrl":"10.3341/kjo.2025.0063","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the 6-month clinical outcomes of accelerated corneal cross-linking (A-CXL) using a total energy dose of 7.2 J/cm2 with a 0.1% dextran-free riboflavin solution containing hydroxypropyl-methylcellulose (HPMC) in patients with progressive keratoconus.</p><p><strong>Methods: </strong>A total of 42 eyes from 35 patients with progressive keratoconus underwent epithelial removal, followed by the application of 0.1% dextran-free riboflavin solution with HPMC every 30 seconds for 10 minutes. A-CXL was performed using ultraviolet A irradiation at 12 mW/cm2 for 10 minutes, delivering a total energy dose of 7.2 J/cm2. Evaluations included uncorrected distance visual acuity, corrected distance visual acuity, keratometric indices (flat, steep, and maximum keratometry), central corneal thickness, endothelial cell density, corneal astigmatism, and demarcation line depth using anterior-segment optical coherence tomography. Each keratometric index was measured three times, and mean values were recorded.</p><p><strong>Results: </strong>Corrected distance visual acuity improved significantly from 0.55 ± 0.29 to 0.36 ± 0.23 logarithm of the minimum angle of resolution (p < 0.001). Keratometric indices showed significant reductions, with the mean maximum keratometry decreasing from 57.06 ± 5.7 to 55.4 ± 5.5 diopters (D; p < 0.001). Astigmatism, as represented by cylindrical power, decreased slightly from -3.98 ± 1.98 D preoperatively to -3.75 ± 1.94 D postoperatively; however, this change was not statistically significant (p = 0.122). Central corneal thickness was significantly reduced from 471.6 ± 32.4 to 461.4 ± 31.7 µm (p < 0.001), while uncorrected distance visual acuity remained unchanged (p = 0.070). The mean demarcation line depth was 287.82 ± 39.77 µm. No significant change was observed in endothelial cell density (p = 0.090), and no minor postoperative complications were encountered.</p><p><strong>Conclusions: </strong>A-CXL using a total energy dose of 7.2 J/cm2 with 0.1% dextran-free riboflavin effectively stabilizes keratoconus progression, significantly improves visual acuity and corneal astigmatism, and preserves endothelial integrity over a 6-month follow-up. Further long-term studies are required to validate these findings.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"339-344"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144532524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Managing Pseudophakic Corneal Edema: Structural Changes and Preliminary Observations on Coenzyme Q10 Use.","authors":"Umay Güvenç, Züleyha Yalnız Akkaya, Ayşe Burcu","doi":"10.3341/kjo.2025.0027","DOIUrl":"10.3341/kjo.2025.0027","url":null,"abstract":"<p><strong>Purpose: </strong>Pseudophakic corneal edema (PCE) remains a significant postoperative challenge despite advancements in cataract surgery, often delaying visual recovery and affecting refractive outcomes. This study investigates the relationship between keratometric and pachymetric changes during PCE resolution, evaluates factors influencing this process, and examines the efficacy of coenzyme Q10 (CoQ10) as an adjunct therapy.</p><p><strong>Methods: </strong>A retrospective study was conducted on 88 patients aged 50 years and older who developed PCE after uneventful phacoemulsification. Corneal assessments were performed using Pentacam HR, focusing on keratometric and pachymetric changes. Patients were monitored weekly until PCE resolution, defined as a return of central corneal thickness within ±30 μm of preoperative values. Patients received standard postoperative treatment, with a subset also receiving CoQ10 as an adjunct therapy.</p><p><strong>Results: </strong>Postoperative visual acuity improved significantly (p < 0.001). Despite pachymetric normalization, persistent keratometric changes were observed, particularly a steepening of posterior curvature (p < 0.001) and increased anterior asphericity (p = 0.047). CoQ10-treated patients exhibited faster edema resolution (p = 0.019), greater reduction in corneal thickness (p = 0.003), and improved transparency. Higher cumulative dissipated energy correlated with increased edema severity (r = 0.419, p < 0.001) and higher cumulative dissipated energy was linked to slower recovery times. Patients with diabetes had a prolonged recovery period compared to nondiabetic patients (p = 0.018), though pachymetric recovery rates were similar. The pachymetric progression index was unreliable in edematous corneas.</p><p><strong>Conclusions: </strong>While visual acuity and pachymetry improved in all patients, persistent topographic changes suggest incomplete structural normalization. Preliminary findings indicate that adjunctive CoQ10 use may support more efficient corneal edema resolution, as evidenced by faster recovery and favorable structural changes. Further prospective studies are warranted to confirm these observations.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"312-322"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144304275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Persistent Postoperative Discomfort 1 Year after Keratorefractive Lenticule Extraction and Implantable Collamer Lens Implantation.","authors":"Bu Ki Kim, Young Taek Chung","doi":"10.3341/kjo.2025.0062","DOIUrl":"10.3341/kjo.2025.0062","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the prevalence and characteristics of persistent postoperative discomfort 1 year after keratorefractive lenticule extraction (KLEX) and implantable collamer lens (ICL) implantation.</p><p><strong>Methods: </strong>This retrospective comparative study included 324 eyes from 324 patients with myopia or myopic astigmatism who underwent bilateral KLEX (n = 227) or ICL implantation (n = 97) at a single center. One year postoperatively, visual outcomes, patient satisfaction, and persistent discomfort symptoms were evaluated using a standardized questionnaire, including symptom frequency, severity, and resolution time.</p><p><strong>Results: </strong>Visual outcomes and overall satisfaction were high and comparable between the two groups (97.3% for KLEX vs. 99.0% for ICL; p = 0.157). Persistent glare and halos were significantly less frequent in the KLEX group than in the ICL group (glare: 50.2% vs. 64.9%, p = 0.045; halos: 48.9% vs. 63.9%, p = 0.034). The time to resolution for these symptoms was significantly shorter in the KLEX group (p = 0.031 and p = 0.024, respectively). In contrast, dryness was more frequent, severe, and bothersome in the KLEX group than in the ICL group (all p < 0.001), and its resolution time was longer (p = 0.008).</p><p><strong>Conclusions: </strong>KLEX and ICL implantation showed distinct profiles of persistent postoperative discomfort at 1 year. ICL implantation was associated with higher rates and longer duration of glare and halos, while KLEX was associated with more severe and persistent dryness. These findings underscore the importance of individualized preoperative counseling and patient selection.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":"353-361"},"PeriodicalIF":0.0,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12358729/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}