Korean journal of ophthalmology : KJO最新文献

{"title":"Introducing an Innovative Tool for Enhanced Precision in Strabismus Surgery: The Suh Botulinum Toxin Forceps.","authors":"Josephine Lu, Shaden H Yassin, Kimia Rezaei, John D Hong, E-Jine Tsai, Tara Mossadeghian, Yan Kefalov, Kourosh Shahraki, Mateen Amin, Donny W Suh","doi":"10.3341/kjo.2025.0115","DOIUrl":"https://doi.org/10.3341/kjo.2025.0115","url":null,"abstract":"","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145002437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative Full Thickness Macular Hole Formation after Vitrectomy for the Removal of Epiretinal Membrane.","authors":"Hyun Ji Jung, Hyun Jin Kim, Soo Chang Cho","doi":"10.3341/kjo.2025.0107","DOIUrl":"https://doi.org/10.3341/kjo.2025.0107","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the incidence, clinical features, risk factors, and outcomes of full-thickness macular hole (FTMH) formation after pars plana vitrectomy (PPV) for the removal of epiretinal membrane (ERM).</p><p><strong>Methods: </strong>This retrospective study reviewed the medical charts of the 309 eyes of the 306 patients with PPV for ERM removal from 2012 to 2024 using clinical data warehouse search. Patients were categorized into two groups; one group with development of macular hole (MH) ('MH' group) and the other group without MH development ('no MH' group) after ERM surgery. Baseline demographics and clinical parameters were compared between the two groups. Risk factors for MH formation were analyzed using univariate and multivariate logistic regression. Surgical outcomes of the cases with MH formation were also analyzed.</p><p><strong>Results: </strong>A total of 141 eyes were included. Five cases developed MH after PPV for ERM removal (incidence 3.5%). In all five cases (100%), ERM was observed at MH detection. In 4 of the 5 patients (80%), CME was present at MH detection. ERM with lamellar hole was significantly associated factors for MH formation (OR=13.11, P=0.018). Preoperative central macular thickness (CMT) showed a marginal association (OR=0.98, P=0.075). Among the four patients who underwent surgery, macular hole was successfully closed in three cases. There was no significant difference in BCVA before and after MH surgery.</p><p><strong>Conclusions: </strong>ERM with LH was a significant factor for MH formation, while thin preoperative CMT showed a marginal association. At the time of MH detection, ERM and CME were observed in most cases, suggesting that tangential traction caused by postoperative ERM or, postoperative CME may represent possible etiologies for MH formation. In patients with ERM with LH or thin CMT, the possibility of MH formation after ERM surgery should be taken into account and careful monitoring is needed.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Ten-Year Clinical Audit on Traumatic Cataract Surgery in a Tertiary Centre in Malaysia.","authors":"Siti Sarah Binti Shokri, Nurul Munirah Binti Mohamad, Siti Nur Baizury Binti Hassan, Juanarita Jaafar, Liza Sharmini Ahmad Tajudin","doi":"10.3341/kjo.2025.0034","DOIUrl":"https://doi.org/10.3341/kjo.2025.0034","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the prevalence of traumatic cataract and factors influencing visual outcomes following cataract extraction in a tertiary centre in Malaysia.</p><p><strong>Methods: </strong>A retrospective review was conducted on patients treated for traumatic cataract at the Department of Ophthalmology, Hospital XXX, between January 2012 and December 2022. Data were retrieved from the Malaysian Cataract Registry. Data of those with history of blunt trauma, secondary cataract surgery, or primary closure with cataract removal post-open globe injuries, with a minimum one-year follow-up post-surgery were extracted from the registry. Their data were retrieved from the medical record unit. The outcome of cataract surgery was based on best corrected visual acuity (BCVA) ≥6/18 as good and <6/18 as poor outcome.</p><p><strong>Results: </strong>A total of 224 patients (113 open-globe and 112 closed-globe injuries) were included, with a mean age of 41.1 ±19.8 years. Men had a 5:1 higher risk. Domestic accidents (34.4%) were the leading cause, followed by agricultural (21.9%) and non-agricultural occupational injuries (21.4%). Preoperatively, 72.8% presented with severe visual impairment. Phacoemulsification was the most common surgical technique (37.1%), and primary intraocular lens (IOL) implantation was performed in 53.1%, while 25.9% remained aphakic. Postoperatively, 46.0% achieved BCVA ≥6/18, while 24.1% remained blind (<3/60). Those with closed-globe injuries were 3.4 times more likely to yield good visual outcomes (p < 0.001). Better preoperative visual acuity, posterior capsule IOL (PCIOL), sulcus and iris fixated IOL is associated with favourable outcome. There was significant correlation between preoperative and postoperative visual acuity (r = 0.306, p < 0.001).</p><p><strong>Conclusions: </strong>Traumatic cataract surgery is not uncommon, but the outcome is unpredictable. Closed-globe injuries, better preoperative visual acuity, PCIOL, sulcus and iris fixated IOL are strong predictors for favourable visual recovery in traumatic cataract surgery. Early intervention, thorough ocular assessment, and tailored surgical planning are crucial for optimal rehabilitation.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of Esodeviation Related to Hyperopia.","authors":"Yi Sang Yoon, Ungsoo Samuel Kim","doi":"10.3341/kjo.2025.0032","DOIUrl":"https://doi.org/10.3341/kjo.2025.0032","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate characteristics of esotropia combined with hyperopia in children 4 to 6 years old.</p><p><strong>Methods: </strong>We retrospectively reviewed medical charts of 142 patients (four to six years old, 60 boys and 82 girls) with esotropia combined with hyperopia ( ≥ 1.5 diopters after cycloplegic refraction). The patients were classified into four groups (group 1; fully corrected accommodative esotropia (FCAET), group 2; remained esotropia ≤ 8 prism diopters (AET), group 3; remained esotropia ≥ 10 prism diopters (partially AET, PAET), and group 4; non-responder group (NAET)). We analyzed various factors (best-corrected visual acuity, angle of esodeviation, refractive errors) to determine which variables predict the type of esodeviation.</p><p><strong>Results: </strong>Girls were well-controlled with glasses (p=0.044). Visual acuity of the better eye and the worse eye, and rate of anisometropic amblyopia were not different among groups (p=0.430, p=0.124, and p=0.189, respectively.). The hyperopia (spherical power) of the AET group was significantly higher than that of the NAET group (p=0.028). The spherical equivalent is also more hyperopic in the AET group than in the NAET group (p=0.040). Near esodeviation in the FCAET was significantly smaller than that of AET (p=0.003). However, the esodeviation in the far distance was not different among groups (p=0.115).</p><p><strong>Conclusion: </strong>Patients with larger angles of esodeviation and lower degrees of hyperopia were more likely not to respond to glasses Therefore, various factors should be considered when predicting outcomes of motor success of accommodative esotropia before the trial of glasses.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144850264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of Pencil Push-up Exercises in Patients with Convergence Insufficiency-type Exotropia with Receded Near Point of Convergence.","authors":"Ju Seouk Lee, Seung Uk Lee, Sang Joon Lee, Chang Zoo Kim","doi":"10.3341/kjo.2025.0085","DOIUrl":"https://doi.org/10.3341/kjo.2025.0085","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the long-term efficacy of home-based convergence exercises using pencil push-ups in adult patients with convergence insufficiency-type exotropia (CI-type XT) with receded near point of convergence (NPC).</p><p><strong>Methods: </strong>This retrospective observational study included 30 adult patients diagnosed with CI-type XT, who were divided into two groups based on their adherence to pencil push-up exercises: a compliant group (n=20) and a non-compliant control group (n=10). Pencil push-ups were performed four times daily (15 repetitions per session) for 6 months. The outcomes were changes in the angle of exodeviation (distance and near), NPC, and stereopsis. Measurements were taken at baseline and after 6 months. Between-group comparisons were performed using parametric statistical tests.</p><p><strong>Results: </strong>The pencil push-ups group showed significant improvement in both distance (from 24.65 ± 5.46 to 14.40 ± 5.71 prism diopters, p<0.001) and near exodeviation (from 35.25 ± 5.36 to 23.85 ± 6.68 prism diopters, p<0.001). NPC improved significantly from 22.6 ± 5.2 cm to 8.6 ± 3.1 cm (p<0.001). In contrast, the non-compliant group showed no significant changes in either parameter. No measurable improvement in stereopsis was observed in either group.</p><p><strong>Conclusion: </strong>Consistent home-based pencil push-up exercises significantly improved convergence and reduced exodeviation in adult patients with CI-type XT with receded NPC. Pencil push-ups may serve as an effective first-line or adjunctive therapy, particularly in motivated patients with moderate deviations.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144850265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and Safety of 7.2 J/cm² Accelerated Corneal Cross-Linking in Pediatric and Adult Keratoconus: A Comparative Study.","authors":"Mustafa Turunç, Ahmet Özdemir, Ertuğrul Can","doi":"10.3341/kjo.2025.0066","DOIUrl":"https://doi.org/10.3341/kjo.2025.0066","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate and compare the short-term outcomes of an accelerated corneal crosslinking (CXL) protocol with a total energy dose of 7.2 J/cm² in pediatric and adult keratoconus patients.</p><p><strong>Methods: </strong>This study included 113 eyes of 82 keratoconus patients who underwent accelerated epithelium-off CXL (12 mW/cm² for 10 minutes) at a university hospital. Patients were divided into two groups based on age: ≤18 years (Group 1, n=48 eyes) and >18 years (Group 2, n=65 eyes). Preoperative and postoperative (6-month) uncorrected visual acuity (UCVA), best-corrected visual acuity (BCVA), keratometric indices (K1, K2, Kmax, Km), central corneal thickness (CCT), and endothelial cell density (ECD) were analyzed and compared between groups.</p><p><strong>Results: </strong>Significant improvements in BCVA and reductions in keratometric indices were observed in both groups (p < 0.05). While both groups demonstrated significant visual and structural improvements, the adult group exhibited a greater magnitude of change in most keratometric and refractive parametersGroup 1 (mean age 15.4 ± 1.6 years) and Group 2 (mean age 23.4 ± 3.4 years) exhibited significant decreases in CCT (p < 0.001). Posterior keratometric values showed statistically significant changes in both groups (p < 0.001). ECD remained stable, and no severe complications were noted.</p><p><strong>Conclusions: </strong>Accelerated CXL with a total energy dose of 7.2 J/cm² demonstrated a favorable safety profile and significant efficacy in stabilizing keratoconus in both pediatric and adult patients over a 6-month period. Notably, adult patients exhibited a greater extent of keratometric and refractive improvement, suggesting a potentially age-dependent biomechanical response. These findings support the utility of this protocol as an early intervention strategy, particularly in young adults with progressive disease.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144850266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment Trends of Diabetic Macular Edema in Korea (TRACK) study: A Prospective Multicenter Study.","authors":"Min Seok Kim, Kwangsic Joo, Yong-Un Shin, Hee Yoon Cho, Joo Yong Lee, Min Sagong, Jee Taek Kim, Yu Cheol Kim, Hyun Woong Kim, Hyunduck Kwak, Seong Joon Ahn, Mee Yon Lee, Jeong Hun Bae, Inyoung Chung, Yong Seop Han, Woong-Sun Yoo, Sungwho Park, Do Gyun Kim, Hae Min Kang, Hee Seung Chin, Daniel Duck-Jin Hwang, Yong-Sok Ji, Kyu Hyung Park","doi":"10.3341/kjo.2025.0057","DOIUrl":"https://doi.org/10.3341/kjo.2025.0057","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate real-world functional and anatomical outcomes, treatment patterns, and ocular examination trends in diabetic macular edema (DME) in Korea.</p><p><strong>Methods: </strong>A prospective, multicenter, observational study was conducted at 17 hospitals (2017-2022) involving adults with DME. Patients were categorized into center-involving (CI DME) and non-center-involving (non-CI DME) groups based on optical coherence tomography findings. Serial changes in best-corrected visual acuity (BCVA), central subfoveal thickness (CST), and treatment and examination patterns were recorded at baseline and follow-up visits (6, 12, 18, and 24 months), and analyzed using linear mixed models and paired t-tests.</p><p><strong>Results: </strong>A total of 209 participants (38.8% women; mean age, 60.2±10.8 years) were enrolled. Over 24 months, 10/68 (14.7%) non-CI DME patients developed CI DME. CST significantly decreased in the CI DME group (from 419µm at baseline to 343µm, P=0.001), whereas BCVA remained unchanged in both groups. Throughout the two-year period, the average number of anti-VEGF injections was 3.1±3.6, while steroid injections averaged 0.7±1.5. The CI DME group received significantly more anti-VEGF injections compared to the non-CI DME group (3.8±3.9 vs. 2.0±2.8, P=0.004). Additionally, the CI DME group had more frequent visits (15.8 vs. 11.3, P=0.017) and OCT examinations (9.7 vs. 7.4, P=0.023). The number of anti-VEGF injections decreased in the CI DME group over time, while the number of visits decreased in both groups.</p><p><strong>Conclusion: </strong>In real-world clinical practice in Korea, the treatment and monitoring frequency for DME was lower than in major clinical trials, potentially contributing to suboptimal visual outcomes.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144824459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Hyperopia Animal Model Using Blue Light in Guinea Pigs.","authors":"Yung Ju Yoo, Jeong-Min Hwang","doi":"10.3341/kjo.2025.0100","DOIUrl":"https://doi.org/10.3341/kjo.2025.0100","url":null,"abstract":"<p><strong>Purpose: </strong>The majority of existing studies have focused on the progression of myopia, while an animal model for hyperopia has not yet been developed. This study aimed to evaluate whether blue light exposure can suppress emmetropization in a manner comparable to lens-induced hyperopia, thereby facilitating the development of an experimental animal model of hyperopia.</p><p><strong>Methods: </strong>Five-day-old 24 guinea pigs were randomly assigned to different experimental groups based on light exposure conditions. They were housed under a 12-hour light/dark cycle (lights on at 8 AM and off at 8 PM) and exposed to either white light (control) or blue light (460 ± 20 nm). To induce hyperopia, a custom-designed +10 diopter (D) lens was fabricated using a 3D printer and securely attached to randomly selected one eye with Velcro and tissue adhesive. Refractive errors, corneal curvature, and axial length were measured using streak retinoscopy and A-scan ultrasound, with repeated measurements to assess inter-eye deviation.</p><p><strong>Results: </strong>At the end of the treatment period (6 weeks), guinea pigs reared under blue light with an attached +10 D lens exhibited a significantly greater hyperopic shift compared to those reared under blue light without the lens. In contrast, guinea pigs raised under white light underwent emmetropization regardless of +10 D lens attachment.</p><p><strong>Conclusion: </strong>Blue light exposure significantly suppresses emmetropization by inducing a marked hyperopic shift in guinea pigs, whereas white light conditions support normal emmetropization regardless of lens attachment. These findings suggest that blue light plays a crucial role in hyperopia induction and can be effectively utilized to establish a stable hyperopia animal model.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144824456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traumatic Retinal Detachment: A Comparative Study in Closed and Open Globe Injuries.","authors":"Jae Hyup Lee, Chang Ki Yoon, Un Chul Park, Kyu Hyung Park, Eun Kyoung Lee","doi":"10.3341/kjo.2025.0036","DOIUrl":"https://doi.org/10.3341/kjo.2025.0036","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the clinical characteristics and prognosis of patients with traumatic retinal detachment (TrRD) based on the mechanism of ocular injury and identify prognostic factors associated with clinical outcomes. We hypothesized that open globe injuries would demonstrate worse clinical presentations and poorer functional outcomes compared to closed globe injuries.</p><p><strong>Methods: </strong>This retrospective study included 98 eyes of 98 patients diagnosed with TrRD who underwent surgery, followed by a minimum of 6 months of postoperative observation. The eyes were categorized into two groups based on the mechanism of ocular injury: closed and open injuries. The clinical presentations and postoperative outcomes of the two groups were evaluated, and factors associated with anatomical and functional success were identified.</p><p><strong>Results: </strong>Thirty-seven (37.8%) and 61 eyes (62.2%) were classified into the closed and open injury groups, respectively. Patients in the open group were more likely to exhibit vitreous hemorrhage (p = 0.003), subretinal hemorrhage (p = 0.003), and retinal incarceration than those in the closed group. Although there was no difference in the anatomical outcomes between the two groups, significantly more patients achieved functional success in the closed group (45.9%) than those in the open group (25.9%; p = 0.043). Anatomical success was associated with the absence of giant retinal tears, retinal incarceration, and proliferative vitreoretinopathy (≥ grade B). Functional success was significantly associated with better baseline best-corrected visual acuity, intraoperative intraocular lens implantation, and no retinectomy during surgery.</p><p><strong>Conclusions: </strong>Despite the clinical presentation variations among patients with TrRD with closed and open injuries, there were no differences in anatomical outcomes between the two groups. Patients in the open group had poorer functional outcomes. By identifying specific prognostic factors associated with anatomical and functional success, this study provides evidence-based guidance for management and prognostication of patients with TrRD.</p>","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144824458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Case of Diffuse Iris Metastasis from Small Cell Lung Cancer.","authors":"HyunWoo Lee, Kwangsic Joo","doi":"10.3341/kjo.2025.0080","DOIUrl":"https://doi.org/10.3341/kjo.2025.0080","url":null,"abstract":"","PeriodicalId":101356,"journal":{"name":"Korean journal of ophthalmology : KJO","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144824455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}