Urology research & practice最新文献_第4页

Diagnosing Dysfunctional Voiding Non-Invasively: The SHADE Criteria Approach. 无创诊断功能障碍排尿：SHADE标准方法。

IF 1.1

Urology research & practice Pub Date : 2025-07-29 DOI: 10.5152/tud.2025.25001

Gautam Shubhankar, Vikas Kumar Panwar, Md Taher Mujahid, Ankur Mittal, Shubham Miglani, Arup Kumar Mandal

{"title":"Diagnosing Dysfunctional Voiding Non-Invasively: The SHADE Criteria Approach.","authors":"Gautam Shubhankar, Vikas Kumar Panwar, Md Taher Mujahid, Ankur Mittal, Shubham Miglani, Arup Kumar Mandal","doi":"10.5152/tud.2025.25001","DOIUrl":"10.5152/tud.2025.25001","url":null,"abstract":"Objective: Dysfunctional voiding (DV) is an often-underdiagnosed condition primarily affecting younger patients with lower urinary tract symptoms (LUTS). Characterized by a lack of coordination between the detrusor muscle and the external urethral sphincter, DV commonly manifests as urinary frequency, urgency, and incontinence. Despite its significant impact, urodynamic studies (UDS), the gold standard for diagnosis, are frequently inaccessible in remote or under-resourced areas. This study investigates non-invasive clinical parameters to facilitate provisional DV diagnosis. Methods: A retrospective analysis of 813 patients who underwent UDS for LUTS over 3 years (2021-2024) was conducted. Excluding those with neurological disorders or urethral strictures, 516 patients were evaluated, identifying 67 with DV. Parameters were examined across 2 age groups: under 50 years and 50 years or older, focusing on symptomatology, uroflowmetry, and associated conditions. Statistical analyses, including Chi-square tests and multivariate logistic regression, were employed to identify significant predictors. Results: Of the 67 patients diagnosed with DV, 64 were under 50 years of age. Statistically significant associations were found between DV and increased diurnal frequency, pre-existing heightened anxiety, obstructive uroflowmetry patterns, constipation, and hypertonic anal sphincter. The proposed non-invasive criteria-SHADE (Staccato/obstructive voiding pattern, Heightened anxiety, Age <50, Diurnal frequency, Exclusion of stricture or neurological disease)-demonstrated over 95% positive predictive value for DV. Conclusion: Early and accurate diagnosis of DV can be enhanced through non invasive clinical criteria, particularly in settings where urodynamic testing is limited. Implementing the SHADE criteria can facilitate prompt, targeted management of DV, improving patient outcomes in resource-constrained environments.","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"51 4","pages":"146-152"},"PeriodicalIF":1.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362486/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vardenafil and Tamsulosin in the Management of Ureteral Stent-Related Symptoms: A Prospective Comparative Study. 伐地那非和坦索罗辛治疗输尿管支架相关症状：一项前瞻性比较研究

IF 1.1

Urology research & practice Pub Date : 2025-07-29 DOI: 10.5152/tud.2025.24111

Ahmed Abdellatif, Ahmed Mohamed, Amr Massoud, Ahmed Abd Elbary, Akram Elmarakbie

{"title":"Vardenafil and Tamsulosin in the Management of Ureteral Stent-Related Symptoms: A Prospective Comparative Study.","authors":"Ahmed Abdellatif, Ahmed Mohamed, Amr Massoud, Ahmed Abd Elbary, Akram Elmarakbie","doi":"10.5152/tud.2025.24111","DOIUrl":"10.5152/tud.2025.24111","url":null,"abstract":"Objective: This study aimed to compare the effectiveness of vardenafil, a phosphodi-esterase-5 inhibitor, and tamsulosin, an alpha-blocker, in the management of ureteral srtent-elated symptoms. Methods: A total of 208 patients who underwent ureteric stent placement after the removal of ureteric stones were enrolled and randomly divided to receive either var- denafil 10 mg daily or tamsulosin 0.4 mg daily for a duration of 3 weeks. The validated Ureteral Stent Symptom Questionnaire (USSQ) was used to assess patients at baseline and after 3 weeks from starting the medications. Results: This study compared tamsulosin and vardenafil in 208 patients (101 vs. 107) with a mean age of 45.07 ± 9.5 years, predominantly male (67.4%); both groups were similar in baseline characteristics (P >.05). A notable statistical significant reduction in total scores from the first visit to the fourth visit (vardenafil: 136.03 to 85.01; tamsulosin: 129.9 to 97). Vardenafil showed a statistically significant improvement (P <.001) compared to tamsulosin across all USSQ domains except body pain, which has statistically significant improvement in the tamsulosin group. During the follow-up visits, vardenafil had statistically significant improvement in all USSQ domains; however, tamsu- losin had statistically significant improvement in all USSQ domains except in sexual health (P =.5). Side effects were mild, with retrograde ejaculation and hypotension in the tamsulosin group and headaches in the vardenafil group. Conclusion: Vardenafil showed promising results in controlling stent-related symptoms and can be considered an alternative or adjunct medication to tamsulosin in the management of stent-related symptoms; however, this needs further exploration in larger, multi-center studies to validate these findings and optimize patient outcomes in clinical practice.","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"51 4","pages":"153-158"},"PeriodicalIF":1.1,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12362527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unraveling Online Perspectives and Misinformation Surrounding Urinary Tract Infections: A Thematic Analysis of 1200 Instagram Posts. 解开关于尿路感染的在线观点和错误信息：对1200个Instagram帖子的专题分析。

IF 1.1

Urology research & practice Pub Date : 2025-06-24 DOI: 10.5152/tud.2025.25033

Raya Dean, Patrick Juliebø-Jones, Amelia Pietropaolo, Naeem Bhojani, Wissam Kamal, Bhaskar Somani

{"title":"Unraveling Online Perspectives and Misinformation Surrounding Urinary Tract Infections: A Thematic Analysis of 1200 Instagram Posts.","authors":"Raya Dean, Patrick Juliebø-Jones, Amelia Pietropaolo, Naeem Bhojani, Wissam Kamal, Bhaskar Somani","doi":"10.5152/tud.2025.25033","DOIUrl":"10.5152/tud.2025.25033","url":null,"abstract":"Objective: Urinary tract infections are burdensome for patients. Social media is increasingly used as a platform for patients and public to seek and share support. The study aimed to evaluate what patients encounter when they turn to Instagram for urinary tract infection-related support and advice. Methods: The first 200 posts appearing on the \"top posts\" section of Instagram for 6 key hashtags (#UTI, #UTIs, #urinarytractinfection, #urinarytractinfections, #bladderin- fection, #bladderinfections) were selected. Thematic analysis (TA) was used to identify themes present in the Instagram captions. Results: Across 1200 posts analyzed, 5 main themes were identified. 1) \"We can help…,\" this was largely commercial advertising with the promotion of healthcare clinics. 2) \"I'm suffering,\" which contained first-person narratives about an unpleasant experience with a disease or treatment as well as frustration at health services. 3)!\"Warning signs,\" posts describing signs or symptoms that the creator claims indicate poor health. 4)!\"Remedies,\" these posts detailed therapies to try, often herbal. 5) \"Avoid and change,\" which covered triggers to avoid symptom flare ups. Conclusion: There is a large amount of content on social media related to UTIs. Urologists should be aware that patients may have sought out advice using these platforms and may therefore have received misinformation and products that have been advertised but lack scientific evidence.","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"51 3","pages":"84-88"},"PeriodicalIF":1.1,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biochemical and Histological Characterization of Sorcin Overexpression in Patients Who Underwent Radical Prostatectomy. 根治性前列腺切除术患者Sorcin过表达的生化和组织学特征。

Urology research & practice Pub Date : 2025-06-24 DOI: 10.5152/tud.2025.24188

Kenan Toprak, Mehmet Gokhan Culha, Huseyin Ozgur Kazan, Ayberk Iplikci, Gozde Kir, Gozde Ecem Cecikoglu, Ahmad Kado, Hayriye Erman, Asif Yildirim

{"title":"Biochemical and Histological Characterization of Sorcin Overexpression in Patients Who Underwent Radical Prostatectomy.","authors":"Kenan Toprak, Mehmet Gokhan Culha, Huseyin Ozgur Kazan, Ayberk Iplikci, Gozde Kir, Gozde Ecem Cecikoglu, Ahmad Kado, Hayriye Erman, Asif Yildirim","doi":"10.5152/tud.2025.24188","DOIUrl":"10.5152/tud.2025.24188","url":null,"abstract":"Objective: Sorcin, a signaling molecule, has recently emerged as a significant focus within cancer research. This study aimed to compare histopathology results with serum sorcin level and tissue sorcin immunohistochemical expression in patients who underwent radical prostatectomy (RP). Methods: A total of 81 patients who underwent RP between December 2017 and June 2019 due to prostate cancer (PCa) and had not received any previous treatment were included in the study. Patients attended regular follow-up appointments for at least 24 months. In order to compare serum sorcin levels, the control group consisted of 67 healthy men. Demographic data of participants were recorded. In the PCa group, pathology data from both Transrectal ultrasound-guided biopsy and RP were documented. Results: Prostate-specific antigen (PSA) and sorcin levels of PCa patients were found to be higher than the control group (P < .001, P = .02). In the comparison of sorcin levels and sorcin staining percentages of PCa patients with histopathological and clinical findings; while sorcin levels were found to be higher in patients with positive lymph nodes (P = .018) and with biochemical recurrence (P = .049), no significant difference was found in any histopathological finding in terms of sorcin staining percentages. In an receiver operating characteristic curve analysis calculation for sorcin levels in PCa patients, AUC = 0.563 and when the cut-off value was taken as 0.415 ng/mL, 59.3% sensitivity 60.1% specificity was determined. Conclusion: Sorcin was found to be higher in PCa compared to healthy males. In addition, high International Society of Urological Pathology grade groups were observed in patients with high sorcin levels.","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"51 3","pages":"105-110"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257818/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the Surgical Results of Ventral and Dorsal Dartos Flaps in Tubularized Incised Plate Urethroplasty for Distal Hypospadias: A Randomized Clinical Trial. 尿道下裂远端管状切开钢板尿道成形术中腹侧和背侧皮瓣手术效果的比较：一项随机临床试验。

Urology research & practice Pub Date : 2025-06-24 DOI: 10.5152/tud.2025.25012

Fateme Tahmasbi, Javad Aliasgarzadeh, Mohsen Mohammad-Rahimi, Behzad Lotfi

{"title":"Comparison of the Surgical Results of Ventral and Dorsal Dartos Flaps in Tubularized Incised Plate Urethroplasty for Distal Hypospadias: A Randomized Clinical Trial.","authors":"Fateme Tahmasbi, Javad Aliasgarzadeh, Mohsen Mohammad-Rahimi, Behzad Lotfi","doi":"10.5152/tud.2025.25012","DOIUrl":"10.5152/tud.2025.25012","url":null,"abstract":"Objective: Hypospadias is one of the most common congenital anomalies of the urogenital system. Various surgical methods exist to repair this condition, all aiming to create a straight penis, ensure proper placement of the meatus, and achieve a sufficient diameter for the urethra with optimal flow. Despite following precise surgical techniques, many patients in reported studies still experience complications. The aim was to evaluate and compare the surgical outcomes of distal hypospadias repair utilizing ventral versus dorsal Dartos flaps. Methods: In this randomized clinical trial, patients who were candidates for surgical treatment were randomly assigned to 2 groups. Both groups underwent hypospadias repair using the tubularized incised plate (TIP) method. The first group received a ventral Dartos flap, while the second group received a dorsal Dartos flap for urethral recon struction. Patients were monitored for complications, and the Hypospadias Objective Scoring Evaluation (HOSE) questionnaire was used to assess the surgical outcomes. Results: The dorsal flap group had higher complication rates, including 3 fistulas (10%), 6 cases of mild necrosis (20%), 2 cases of severe necrosis (6.7%), and 4 instances of penile torsion (13.3%). The ventral flap group had 2 cases (6.7%) of postoperative bleeding and 2 fistulas (6.7%). At the 6-month follow-up, no significant difference was observed between the 2 groups in terms of HOSE score. The need for reoperation was higher in the dorsal flap group. Fateme Tahmasbi1,2 Javad Aliasgarzadeh3 Mohsen Mohammad-Rahimi4 Behzad Lotfi3 Conclusion: The findings suggest that the ventral Dartos flap provides better results and fewer complications than the dorsal Dartos flap in the repair of hypospadias.","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"51 3","pages":"111-116"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transvaginal Repair of Supratrigonal, Juxtacervical, Vault, and Apical Vesicovaginal Fistulae: A Systematic Review and Meta-Analysis. 经阴道修复膀胱阴道上瘘、宫颈旁瘘、穹窿瘘和根尖瘘：系统回顾和荟萃分析。

Urology research & practice Pub Date : 2025-06-24 DOI: 10.5152/tud.2025.24184

Mugdha Srivastava, Ankur Mittal, Vikas Kumar Panwar, Yogesh Bahurupi, Arup Kumar Mandal

{"title":"Transvaginal Repair of Supratrigonal, Juxtacervical, Vault, and Apical Vesicovaginal Fistulae: A Systematic Review and Meta-Analysis.","authors":"Mugdha Srivastava, Ankur Mittal, Vikas Kumar Panwar, Yogesh Bahurupi, Arup Kumar Mandal","doi":"10.5152/tud.2025.24184","DOIUrl":"10.5152/tud.2025.24184","url":null,"abstract":"Objective: This systematic review and meta-analysis assesses the success rate, surgical and quality of life outcomes, and complications of vaginal repair of supratrigonal, jux tacervical, vault, and apical vesicovaginal fistulae (VVF) as a group. Methods: PubMed, Embase, and Cochrane were searched for studies published from January 2003 to August 2023. Sixteen (n = 612) and 15 (n = 568) studies were included in the review and meta-analysis, respectively. Risk of bias assessment was done using the Methodological Index for Non-Randomized Studies (MINORS) criteria. Four studies (n = 196) reported sexual health outcomes. Comprehensive meta-analysis software (trial version 3) was used for quantitative synthesis. Results: The success rate (95% CI) of vaginal repair of this specific group of VVF using a random effects model was 86.3% (76.5%-92.4%). I2 was 73.72% with a Q-value of 53.27. The mean age of patients was 43.7 years. Follow-up duration ranged from 1 to 84 months. There were no major intraoperative complications except for 1 inadvertent bowel injury. Postoperative complications included Urinary tract infections (n = 5), stress incontinence (n = 2), urge incontinence (n = 2), hematuria (n = 3), and vaginal bleeding (n = 3). One hundred eighty-four patients reported no sexual dysfunction, while 6 patients had a Female Sexual Function Index score ! 26.5. Conclusion: The studies included in this meta-analysis are largely heterogeneous and retrospective, which is a limitation of this meta-analysis. Despite this, the results of this meta-analysis confirm successful correction of most of the VVF included in this review by the transvaginal route. While preferences for a given surgical approach may vary based on the number and size of the VVF or vaginal capacity, these factors need to be studied prospectively to understand their role in deciding the route of repair.","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"51 3","pages":"117-130"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257816/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is There a Role for Music Intervention in Reducing Anxiety and Pain in Males During Outpatient Flexible Cystoscopy? A Randomized Controlled Study. 音乐干预在减少男性门诊柔性膀胱镜检查时的焦虑和疼痛中是否有作用？随机对照研究。

Urology research & practice Pub Date : 2025-06-24 DOI: 10.5152/tud.2025.25027

Atsushi Wanifuchi, Toshiaki Tanaka, Tetsuya Shindo, Yuki Kyoda, Kohei Hashimoto, Naoya Masumori

{"title":"Is There a Role for Music Intervention in Reducing Anxiety and Pain in Males During Outpatient Flexible Cystoscopy? A Randomized Controlled Study.","authors":"Atsushi Wanifuchi, Toshiaki Tanaka, Tetsuya Shindo, Yuki Kyoda, Kohei Hashimoto, Naoya Masumori","doi":"10.5152/tud.2025.25027","DOIUrl":"10.5152/tud.2025.25027","url":null,"abstract":"Objective: To prospectively verify whether music intervention reduces the anxiety and pain in male patients undergoing outpatient flexible cystoscopy in a randomized control trial. Methods: A total of 100 male patients undergoing outpatient flexible cystoscopy from May to November 2023 were randomly assigned to the music intervention group or control group. Spielberger's State-Trait Anxiety Inventory (STAI) was used to assess the anxiety. The primary outcome was difference in the change of STAI-S level before and after the flexible cystoscopy between the groups. The secondary outcomes were pain and satisfaction measured by visual analogue scale (VAS). In addition, physiological change was assessed between the groups. Results: A total of 93 patients (48 in the music group and 45 in the control group) were included in the final analysis. Baseline characteristics were comparable between the groups. The median change of STAI-S in the music group was significantly greater than that in the control group (!5 vs !2, P = .03). The music group showed significantly lower pain and higher satisfaction on VAS after cystoscopy compared with the control group. By contrast, the change of physiological parameters was comparable between the groups. Conclusion: Music intervention may be useful to reduce both pain and anxiety associated with outpatient flexible cystoscopy in male patients.","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"51 3","pages":"99-104"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retrieval of Knotted and Stripped Guidewires Lost During Percutaneous Intervention on Kidney-A Case Series and Review of Literature. 经皮肾介入治疗中丢失的导丝打结和脱落的恢复-病例系列和文献回顾。

Urology research & practice Pub Date : 2025-06-24 DOI: 10.5152/tud.2025.24159

Sajad Ahmad Para, Sajad Ahmad Malik, Prince Muzafer Wani, Arif Hamid, Abdul Rouf Khawaja, Saqib Mehdi

{"title":"Retrieval of Knotted and Stripped Guidewires Lost During Percutaneous Intervention on Kidney-A Case Series and Review of Literature.","authors":"Sajad Ahmad Para, Sajad Ahmad Malik, Prince Muzafer Wani, Arif Hamid, Abdul Rouf Khawaja, Saqib Mehdi","doi":"10.5152/tud.2025.24159","DOIUrl":"10.5152/tud.2025.24159","url":null,"abstract":"Objective: The complication associated with percutaneous interventions done on kidneys are usually easily identified and managed with defined protocols. These usually include bleeding, surrounding organ injury, or sepsis. Stripping or knotting of glidewire during these procedures is rare and have no defined management guidelines. There is a paucity in the literature about the management of these complications. A case series is reported on the management of this rare complication. Methods: A case series of 3 patients is presented, with 1 patient experiencing stripping of the glidewire and the other 2 having knotting of glidewire that got stuck during the percutaneous intervention done on the kidney. The guidewires were removed percutaneously with fluoroscopic guidance, thus avoiding the more morbid procedures of open surgery. Results: The stripped and knotted guidewires were removed percutaneously under fluroscopic guidance. we did not report failure or a complication in any of the cases. Conclusion: Stripping or knotting of guidewires is a rare complication occurring during many percutaneous procedures done on kidneys. They can be safely removed percutaneously with fluoroscopic assistance and the use of conventional endoscopic equipment. Lasers play an indispensable role in the management of these complications.","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"51 3","pages":"95-98"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mini-Endoscopic Combined Intrarenal Surgery in Patients with Poor Performance Status: A Retrospective Analysis of Postoperative Fever in Over 1000 Cases. 微创内镜联合肾内手术治疗肾功能不佳患者：1000余例术后发热的回顾性分析。

Urology research & practice Pub Date : 2025-06-24 DOI: 10.5152/tud.2025.25013

Tadashi Tabei, Hiroki Ito, Takaaki Inoue, Takahiko Watanab, Tetsuo Fukuda, Fukashi Yamamichi, Yosuke Shibata, Junichi Matsuzaki, Kazuki Kobayashi

{"title":"Mini-Endoscopic Combined Intrarenal Surgery in Patients with Poor Performance Status: A Retrospective Analysis of Postoperative Fever in Over 1000 Cases.","authors":"Tadashi Tabei, Hiroki Ito, Takaaki Inoue, Takahiko Watanab, Tetsuo Fukuda, Fukashi Yamamichi, Yosuke Shibata, Junichi Matsuzaki, Kazuki Kobayashi","doi":"10.5152/tud.2025.25013","DOIUrl":"10.5152/tud.2025.25013","url":null,"abstract":"Objective: To assess the safety of mini-endoscopic combined intrarenal surgery (mini-ECIRS) in patients with a poor performance status (PS). Methods: A retrospective analysis was conducted on 1132 patients who underwent mini-ECIRS at 3 hospitals between January 2015 and December 2021. Patients were classified according to their PS (PS0-1 and PS2-4 groups) and compared between the groups in terms of preoperative drainage status, such as ureteral stent or percutaneous nephrostomy (PNS), stone characteristics, surgical outcomes, and postoperative fever. Multivariate logistic regression models were used to identify the predictive factors for postoperative fever in each PS group. Results: Patients in the PS2-4 group were older and had a higher stone burden than those in the PS0-1 group. The stone-free rates and surgical success rate were similar between the PS groups, but PS2-4 patients had higher rates of postoperative fever without preoperative drainage. Stone composition analysis revealed a higher prevalence of infectious stones in the PS2-4 group. In the PS0-1 group, PNS reduced postoperative fever risk (odds ratio (OR): 0.65, 95% CI: 0.48-0.89, P = .01), and history of febrile urinary tract infection, stone burden ! 30 mm, number of involved calyces ! 4, and female sex were independent risk factors. Notably, in the PS2-4 group, PNS remained effective against postoperative fever (OR: 0.24, 95% CI: 0.07-0.80, P = .02), while no other factors were significant. Conclusion: The mini-ECIRS was effective even in PS-poor patients, and they may benefit more from preoperative PNS placement than normal PS cases.","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"51 3","pages":"89-94"},"PeriodicalIF":0.0,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12257728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144562538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimized Surgical Outcomes in Living Donor Nephrectomy: A Single-Center Experience with 250 Cases Using a Novel Technique. 活体供肾切除术的最佳手术效果：250例使用新技术的单中心经验。

Urology research & practice Pub Date : 2025-06-04 DOI: 10.5152/tud.2025.25030

Amil Huseynov

{"title":"Optimized Surgical Outcomes in Living Donor Nephrectomy: A Single-Center Experience with 250 Cases Using a Novel Technique.","authors":"Amil Huseynov","doi":"10.5152/tud.2025.25030","DOIUrl":"10.5152/tud.2025.25030","url":null,"abstract":"Objective: Laparoscopic donor nephrectomy has become a standard of care for living kidney donors, providing reduced morbidity, quicker recovery, and enhanced patient satisfaction compared with open techniques. This study evaluates a modified laparoscopic donor nephrectomy technique designed to minimize colon mobilization while optimizing visualization, thereby improving donor outcomes. Methods: A cross-sectional study of 250 consecutive living donor nephrectomies performed by a single surgeon between March 2022 and March 2024 was conducted. All donors underwent preoperative imaging (3D computed tomography and computed tomographic angiography). The modified approach avoided splenic flexure dissection and introduced early ligation of the adrenal vein. We analyzed intraoperative parameters (operative time, estimated blood loss, complications) and postoperative measures (hospital stay, pain scores, complication rates, satisfaction) were analyzed. Results: The mean operative time was 72.8 ± 16.2 minutes, with an estimated blood loss of 100 ± 40 mL. No conversions to open surgery or intraoperative transfusions were required. The mean length of hospital stay was 2.0 ± 1.0 days. Postoperative pain (mean Visual Analog Scale [VAS] 2.5 ± 1.8) was low, and major vascular injury occurred in 0.8% of cases. Wound infection and incisional hernia rates were each 0.8%. Patient satisfaction was high (Patient Satisfaction Questionnaire [PSQ] 3.3 ± 1.4), indicating favorable perceptions of comfort and outcomes. Conclusion: This modified laparoscopic donor nephrectomy technique is safe, effective, and associated with enhanced patient comfort and reduced complications. The findings underscore its potential to improve donor experiences, potentially expanding the living donor pool. Further investigations should confirm these outcomes over a longer follow-up period.","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"51 2","pages":"77-81"},"PeriodicalIF":0.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12208922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144319124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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