Urology research & practice最新文献

{"title":"Interim Results of Rigicon Penile Prosthesis Implantation in a Single Center: The Largest Series in Türkiye.","authors":"Muhammet İhsan Karaman, Rasim Güzel, Duygu Kirkik, Orhan Koca","doi":"10.5152/tud.2025.24122","DOIUrl":"10.5152/tud.2025.24122","url":null,"abstract":"<p><strong>Objective: </strong>To analyze data from patient information forms (PIFs) submitted to the manufacturer of a new 3-piece inflatable penile prosthesis (IPP), the Rigicon Infla10® , to summarize interim outcomes of 250 implantations in a single center, which is the largest series in Türkiye.</p><p><strong>Methods: </strong>A retrospective review of PIFs from 250 patients implanted with the IPP between January 2021 and December 2023 was performed to assess patient characteristics, surgical data, device durability, patient satisfaction, and rates of reoperation for any reason.</p><p><strong>Results: </strong>The mean ± SD (range) follow-up was 21.2 ± 8.7 (6-36) months and the mean ± SD patient age was 56.2 ± 9.1 years. The average surgical time was 47 minutes. Of the total, 2.4% of devices required removal or revision. Mechanical failure of the device was reported in 3 patients (1.2%). One patient (0.4%) required revision for noise during pumping. Two patients (0.8%) requested device removal because of dissatisfaction. No infections were observed in this series. A total of 97.6% of the Rigicon Infla10® devices were free from explant or revision. The satisfaction rate based on a single question asked to the patient by the surgeon 6 months after surgery was 98.4%.</p><p><strong>Conclusion: </strong>All Rigicon Infla10® IPPs implanted in the center prior to January 2024 were included in the retrospective analysis of volunteered PIFs. Initial durability from reoperation was demonstrated to be superior compared to other contemporary devices. Additionally, high satisfaction with treatment outcomes was reported by 92.4% of patients.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 4","pages":"234-239"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11883673/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Chatbot Responses to the Most Popular Questions Regarding Erectile Dysfunction.","authors":"İrfan Şafak Barlas, Lütfi Tunç","doi":"10.5152/tud.2025.24098","DOIUrl":"10.5152/tud.2025.24098","url":null,"abstract":"<p><strong>Objective: </strong>Erectile dysfunction (ED) is a common cause of male sexual dysfunction. We aimed to evaluate the quality of ChatGPT and Gemini's responses to the most frequently asked questions about ED.</p><p><strong>Methods: </strong>This study was conducted as a cross-sectional, observational study. Google Trends was used to determine the most frequently asked questions on the internet. ChatGPT-3.5 and Gemini were compared for these chatbots' answers to the questions about ED. Two urologists with board certificates assessed the quality of responses using the Global Quality Score (GQS).</p><p><strong>Results: </strong>Fifteen questions about ED were included according to the Google Trends. ChatGPT was able to answer all the questions systematically, whereas Gemini could not answer two questions. Upon assessing the quality of the responses provided by both researchers with the GQS, it was observed that the frequency of low-quality responses from Gemini exceeded that of ChatGPT. The agreement between researchers was 92% for ChatGPT and 95% for Gemini.</p><p><strong>Conclusion: </strong>Despite the expeditious and comprehensive answers provided by chatbots, we identified inadequacies in their responses related to ED. In their current state, they cannot replace the patient-centered approach of healthcare professionals and require further development.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 4","pages":"253-260"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11883663/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Affecting the Presence of Renal Cortical Cysts in Kidney Donors.","authors":"Sevim Nuran Kuşlu Çiçek, Amil Huseynov","doi":"10.5152/tud.2025.24116","DOIUrl":"10.5152/tud.2025.24116","url":null,"abstract":"<p><strong>Objective: </strong>Simple renal cysts (SRCs) represent the most frequently occurring type of renal cysts, frequently observed in the elderly population. While generally considered benign, SRCs may sometimes be connected to comorbid conditions such as hypertension, aortic diseases, and renal dysfunction. This research aims to investigate the factors influencing the development of SRCs in kidney donors and the associated risks.</p><p><strong>Methods: </strong>This retrospective cohort study included 1012 living kidney donors, aged 18-87 years, who underwent renal transplant donor nephrectomy between 2008 and 2023. Data on demographic information, cyst characteristics, comorbidities, and associated risk factors were collected and analyzed using statistical methods, including Binary Logistic Regression Analysis. Renal cysts were identified and classified using computed tomography (CT) and magnetic resonance imaging (MRI) methods.</p><p><strong>Results: </strong>Renal cortical cysts were more frequently observed in males (52.76%) compared to females (47.24%), with a significant difference (P=.031). Donors with renal cortical cysts were significantly older (mean age 54.43 ± 12.17 years) compared to those without cysts (46.26 ± 12.35 years, P < .001). Substantial differences were likewise noted in fasting blood glucose, uric acid, creatinine, HbA1c, and glomerular filtration rate (GFR). The prevalence of aortic atherosclerosis was notably elevated in donors with cysts (47.74%) compared to those without (23.57%, P < .001). Binary logistic regression analysis indicated that older age and being male were significant factors influencing the presence of cortical cysts.</p><p><strong>Conclusion: </strong>The study confirms that SRCs are the most common renal cyst type and are more frequently observed in the elderly population. While generally benign, SRCs may be associated with increased uric acid levels and other comorbidities, suggesting potential impacts on kidney health. Additional studies are required to investigate these associations. The presence of SRCs in kidney donors is significantly associated with male gender, age, uric acid levels, and creatinine levels. These findings should be considered during the evaluation of potential kidney donors, particularly regarding the associated risks and management of SRCs.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 4","pages":"225-229"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11883662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meta Analysis of Efficacy and Safety of Prostate Biopsy: A Comparison Between Transperineal and Transrectal Approach.","authors":"Syah Mirsya Warli, Stivano Rizky Valentino Torry, Dhirajaya Dharma Kadar, Ginanda Putra Siregar, Fauriski Febrian Prapiska","doi":"10.5152/tud.2025.24094","DOIUrl":"10.5152/tud.2025.24094","url":null,"abstract":"<p><p>Improved prostate biopsy procedures have been developed to overcome traditional limitations, aiming to enhance cancer diagnosis accuracy. To assess the existing knowledge of the effectiveness and risks linked to transperineal (TP) vs. transrectal (TR) prostate biopsy. Approaches: a comprehensive search was carried out in PubMed, Embase, Web of Science, and Cochrane Library to locate all pertinent papers published till June 8, 2023. Data on cancer detection rate and complications after prostate biopsy were gathered and analyzed via Review Manager software. A subgroup analysis was conducted to evaluate the influence of the study type. A total of 19 publications, involving 80133 patients with suspicion of prostate cancer who underwent prostate biopsy, were enrolled in the analysis. The pooled estimate demonstrated no significant differences in the cancer detection rate between TR and TP (risk difference (RD)=0.03; 95% CI: -0.01 to 0.08; P = .12). In terms of complications, the TP approach significantly decreased the risk of rectal bleeding (odds ratio (OR)=0.24; 95% CI: 0.12-0.51; P < .001), fever and urinary tract infection (OR=0.28; 95% CI: 0.15-0.52; P < .001), and sepsis (OR=0.50; 95% CI: 0.28-0.90; P=.02) compared to the TR approach. In conclusion, there was no significant disparity in the cancer detection rate between TP and TR approaches. However, the TP strategy exhibited an advantage over TR due to a reduced risk of infection and rectal bleeding. Further research is needed to validate these results and develop a more efficient diagnostic approach for prostate cancer.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 4","pages":"208-218"},"PeriodicalIF":0.0,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11883667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143054732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Value of TGF-β Expression in Bladder Cancer: A Systematic Review and Meta-analysis.","authors":"Shima Kianmehr, Mohammad Vahabirad, Atefeh Seghatoleslam, Erfan Sadeghi, Roozbeh Kiani, Hadi Ghasemi","doi":"10.5152/tud.2024.24024","DOIUrl":"10.5152/tud.2024.24024","url":null,"abstract":"<p><strong>Objective: </strong>Transforming growth factor beta (TGF-β) is a member of the growth factor superfamily that clinical studies address its association with bladder cancer invasion, progression, and metastasis. The present systematic review and meta-analysis aimed to explore the prognostic significance of TGF-β expression in bladder cancer patients.</p><p><strong>Materials and methods: </strong>The major international databases, including PubMed, Web of Science, Embase, and Scopus, were searched for full-text literature citations. The hazard ratio (HR) with a 95% CI as the effect size was applied as the appropriate summarized statistic. We used a random-effects model using the DerSimonian and Laird method to estimate the pooled effect size. To assess the heterogeneity among trials, the I-square (I 2 ) statistic and Cochran's Q test were used. Forest and funnel plots were drawn to respectively demonstrate the findings and detect any existing publication bias.</p><p><strong>Results: </strong>This meta-analysis included 3 studies that met the criteria and included 535 patients. The combined HR for the selected studies was 2.250 (95% CI=(1.411, 3.586), P< .001) and no significant heterogeneity was detected between trials (I 2=58.63, P=.089). Furthermore, no severe asymmetry was seen within the funnel plot, indicating a lack of potential publication bias.</p><p><strong>Conclusion: </strong>Our findings suggest that TGF-β expression can remarkably predict a worse prognosis in patients with bladder cancer. The results of the present meta-analysis may be validated through further updated reviews and additional relevant investigations in future studies.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 3","pages":"148-153"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142570416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urogenital Tuberculosis and Delayed Diagnosis: A Qualitative Study.","authors":"Augusto de Azevedo Barreto, Humberto Elias Lopes, José Murillo Bastos Netto, André Avarese Figueiredo","doi":"10.5152/tud.2024.24028","DOIUrl":"10.5152/tud.2024.24028","url":null,"abstract":"<p><strong>Objectives: </strong>To identify the causes of delayed diagnosis of urogenital tuberculosis (UGT) through a qualitative study of patients with contracted bladder due to UGT.</p><p><strong>Materials and methods: </strong>Eight patients diagnosed with contracted bladder due to UGT were evaluated. Data were obtained using face-to-face in-depth interviews and supplemented with medical records analysis and personal medical files. The identification of situations of diagnosis delay was coded by 2 urologists after data analyses. Codes were divided into 3 categories related to its causes: (1) health system; (2) disease factors; and (3) medical factors.</p><p><strong>Results: </strong>The 8 interviews produced 220 minutes of audio and 1.3 GB of scanned documents. The most frequent categories were \"Medical factors,\" followed by \"Disease factors\" and \"Health system.\" The codes \"No clinical-laboratory-radiological suspicion\" and \"No clinical suspicion\" were the most frequent, both belonging to \"Medical factors.\" Clinically, tuberculosis simulates other pathologies and lacks specific tests with adequate sensitivity. The low representation of \"Health system\" codes indicates that access to public and private health services does not influence delayed diagnosis. The lack of clinical and radiological suspicion and the lack of knowledge of UGT features are the main reasons for diagnosis delay.</p><p><strong>Conclusions: </strong>The causes of delayed diagnosis in our sample were related to \"Medical factors,\" followed by \"Disease factors.\" Better understanding UGT features is an important topic in continuous medical education.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 3","pages":"198-202"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uncovering the Evidence for Sustainability in Urology: A Scoping Review.","authors":"Habeeb Abdulrasheed, Ayokunle Adenipekun, Waleed Elsayed, Mohamed S Mohsin, Daniel Madarshahian, Humood Almedej, Banan Osman","doi":"10.5152/tud.2024.24093","DOIUrl":"10.5152/tud.2024.24093","url":null,"abstract":"<p><strong>Objective: </strong>This article focuses on the environmental impact of urology devices and procedures in hospitals and identifies practices that can reduce greenhouse gas emissions associated with urology services.</p><p><strong>Materials and methods: </strong>A scoping review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was conducted using MEDLINE, EMBASE, and Google Scholar to find studies on the carbon footprint of urologic procedures and sustainable practices.</p><p><strong>Results: </strong>We identified 14 studies, 6 of which used life cycle assessments to compare the environmental impact of single-use and reusable urology devices. Three studies favored single-use devices, 2 favored reusable ones, and 1 found no significant difference, with the sterilization of reusable devices being a major carbon contributor. To enhance sustainability in urology, 8 articles suggested measures including day-case procedures, minimizing low-value care, drapeless cystoscopy, fluid management systems, using quick response (QR) codes in documentation, telehealth initiatives, and low-emission anesthetics.</p><p><strong>Conclusion: </strong>Promoting sustainability in healthcare requires more than just using reusable equipment; it necessitates a comprehensive approach from manufacturing to disposal, including the carbon footprint of sterilization. Encouraging low-emission anesthetics, QR codes, and telemedicine can significantly reduce emissions in urology.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 3","pages":"160-166"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Minho Technique\" for Laparoscopic Radical Cystectomy with Intracorporeal Ileal Conduit.","authors":"Andreia Cardoso, Sara Anacleto, Catarina Laranjo Tinoco, Ana Sofia Araújo, Mariana Capinha, Luís Borges Pinto, Aparício Coutinho, Catarina Tavares, Vera Marques, Paulo Mota, Miguel Mendes, Carlos Oliveira, João Pimentel Torres, Emanuel Carvalho-Dias","doi":"10.5152/tud.2024.23230","DOIUrl":"10.5152/tud.2024.23230","url":null,"abstract":"<p><strong>Objective: </strong>Radical cystectomy (RC) with ileal conduit (IC) remains a main treatment for muscle-invasive bladder cancer (MIBC). Laparoscopy in this multistage surgery is quite demanding, so laparoscopic RC (LRC) with intracorporeal IC (IIC) is a technically exceptional procedure. We aim to simplify it, demonstrating our technique, step-by-step. We present a 4-port LRC with IIC and Bricker uretero-ileal anastomoses. The main difference is the immediate and complete posterior dissection, similar to the \"Montsouris approach\" for prostatectomy.</p><p><strong>Materials and methods: </strong>A 70-year-old man with a 5 cm MIBC was subjected to our demonstrated procedure.</p><p><strong>Results: </strong>The postoperative period was uneventful. Diet and ambulation: 2 days. Single-J stents removal: 4 weeks. MIBC N0 was confirmed. At 24 months, the patient is well, without complications (namely hydronephrosis or disease recurrence).</p><p><strong>Conclusion: </strong>LRC with IIC is demanding and requires laparoscopic expertise. However, if performed in a standardized fashion, as demonstrated through this case, and considering our center's experience, it seems feasible and safe with 4-port and standard material without a significant operative time increase, nor oncological or functional compromise.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 3","pages":"203-207"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Psychosocial Impact of Urinary Dysfunction.","authors":"Stephanie Gleicher, Elisabeth M Sebesta, Roger R Dmochowski","doi":"10.5152/tud.2024.23217","DOIUrl":"10.5152/tud.2024.23217","url":null,"abstract":"<p><p>Urinary dysfunction encompasses a wide range of syndromes and symptoms and is highly prevalent among the adult population. Urinary issues have been associated with psychosocial sequelae. The interplay between psychosocial comorbidity and symptoms impacts perceived severity and treatment success. While the correlation has been described in the literature, much remains unknown. This article describes the psychosocial impact on conditions such as overactive bladder (OAB), neurogenic lower urinary tract dysfunction (LUTD), recurrent urinary tract infection (UTI), and interstitial cystitis/bladder pain syndrome (IC/BPS). This article also highlights potential interventions for patients afflicted with both urinary disorders and psychosocial comorbidity to improve overall treatment success.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 3","pages":"167-172"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hounsfield Unit on Preoperative Computed Tomography as an Indicator of Prognosis in Patients with Liposarcoma.","authors":"Ryo Andy Ogasawara, Shugo Yajima, Naoki Imasato, Kohei Hirose, Ken Sekiya, Madoka Kataoka, Yasukazu Nakanishi, Hitoshi Masuda","doi":"10.5152/tud.2024.24032","DOIUrl":"10.5152/tud.2024.24032","url":null,"abstract":"<p><strong>Objective: </strong>Liposarcoma (LPS) is classified into 4 subtypes. As some subtypes have a high recurrence rate, knowing the risk of recurrence before surgery is important. Here, we aimed to investigate the relationship between Hounsfield units (HU) derived from preoperative computed tomography (CT) and the prognosis of patients undergoing surgery.</p><p><strong>Materials and methods: </strong>We included 32 patients who underwent surgery for LPS between 2014 and 2022. Preoperative plain CT images were collected, and the HU value of each LPS was measured. The association between 2 HU categories (HU < cut-off vs. ≥ cut-off) and clinical variables was assessed. The optimal cut-off value was determined using statistical methods. We used the Kaplan-Meier method to determine the differences between the 2 HU categories at 2 endpoints: recurrence-free survival (RFS) and overall survival (OS).</p><p><strong>Results: </strong>The dedifferentiated subtype showed significantly higher HU values than the other subtypes (P < .001). The optimal cut-off value for HU was 20. HU < 20 was associated with young age, low-performance status, low Charlson Comorbidity Index, and well-differentiated pathology. The Kaplan-Meier curves demonstrated that RFS and OS were significantly shorter in patients with HU ≥ 20 than in those with HU < 20 (P = .007 and .04, respectively). However, when stratified based on subtype, no significant differences were observed between dedifferentiated and other subtypes.</p><p><strong>Conclusion: </strong>HU ≥ 20 on preoperative CT was associated with poor prognosis in LPS patients. Our findings suggest that preoperative CT-derived HU values may serve as useful predictors of prognosis.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 3","pages":"187-192"},"PeriodicalIF":0.0,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}