Urology research & practice最新文献

{"title":"Gap of Research to Practice in IC/BPS: A Scientometric Study of Available Evidence.","authors":"Helia Mostafaei, Hamidreza Ashayeri, Sayeh Afshar, Hadi Mostafaei, Tannaz Aghaei Badr, Hanieh Salehi-Pourmehr, Sakineh Hajebrahimi","doi":"10.5152/tud.2025.24086","DOIUrl":"https://doi.org/10.5152/tud.2025.24086","url":null,"abstract":"<p><p>Our main objective is to first characterize the current status of the research field of interstitial cystitis and bladder pain syndrome (IC/BPS). This is achieved by mapping, analyzing, and sub-analyzing the field with a scientometric approach, which provides insights into future research. In September 2023, the Scopus database was searched without restrictions on language and date. The following search query was used: Bladder* W/5 pain* W/3 syndrome* AND Interstitial* W/3 (Cystitis* OR Cystides) and the Scopus filters were used to exclude short surveys, book chapters, editorials, notes, and guidelines. The author, journal, institution data, keywords, average citation, countries, and sources were transformed using a Biblioshiny tool (A Shiny app for Bibliometrix), accounting for author spelling, institutional naming, and subgrouping variations. The search strategy yielded 1833 studies. The USA was the most cited country, with other countries showing significant growth in recent years. In terms of affiliations, TZU CHI University was the most relevant in this field (n = 154). The most relevant keywords were \"female,\" \"interstitial cystitis,\" \"human,\" \"cystitis interstitial,\" \"male,\" and \"cystalgia.\" The current topics in IC/BPS research are Genome-wide association and Cannabidiols. By understanding the past, scientific gaps, and the direction of the current research, researchers can aim for their research questions and conduct their research more organized. The scientific gaps of IC/BPS can be effectively understood by paying attention to the models used in this research, which are the results of the systemic analysis of the scientific products in this research field.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 6","pages":"332-342"},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015755/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Men's Health & Sexual Medicine and the Litigious Patient: A Review of Malpractice Cases.","authors":"Sandeep Sai Voleti, Summer Ghaith, Christopher Warren, Nahid Punjani","doi":"10.5152/tud.2025.24163","DOIUrl":"https://doi.org/10.5152/tud.2025.24163","url":null,"abstract":"<p><strong>Objective: </strong>Recent literature suggests growing rates of malpractice claims against urologists. These cases provide insight into errors that may lead to litigation. We aim to analyze malpractice suits related to men's health and highlight clinical presentations and legal outcomes.</p><p><strong>Methods: </strong>Per STROBE guidelines, we searched the publicly available Thomson Reuters Westlaw legal database for \"jury verdicts and settlements\" from January 1970 to August 2023 to identify medical malpractice cases in Urology. Patient demographics, clinical presentation, alleged error, and legal outcomes were abstracted during a full case review by an independent screener. Cases related to men's sexual health or fertility that named a urologist as the defendant were fully analyzed.</p><p><strong>Results: </strong>A total of 553 urology cases were extracted, with 23 men's health related cases subsequently analyzed. The most common conditions associated with litigation were penile prosthesis (39%), epidydimal pathology (13%), and varicocele (13%). The most common allegations were misdiagnosis (26%), surgical complication (22%), lack of informed consent (22%), and violation of standard of care (22%). Of the 23 cases, 57% ruled \"no liability\" in favor of the urologist and 39% ruled in favor of the plaintiff with a median award of $335,000 (IQR = 100 ,000-450, with 000). Among cases ruled as negligent, performing the incorrect procedure, surgical complications, and violating the standard of care were prominent allegations.</p><p><strong>Conclusions: </strong>This study characterizes malpractice cases related to men's sexual health naming urologists as defendants. Obtaining comprehensive informed consent, following national guidelines, and responding appropriately to surgical complications may minimize likelihood of litigation and maximize patient outcomes.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 6","pages":"328-331"},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laparoscopic Hand-Assisted Donor Nephrectomy: A Decade of Single-Center Experience and Outcomes.","authors":"Sevim Nuran Kuşlu Çiçek, Amil Huseynov","doi":"10.5152/tud.2025.24161","DOIUrl":"https://doi.org/10.5152/tud.2025.24161","url":null,"abstract":"<p><strong>Objective: </strong>Kidney transplantation is the most effective treatment for end-stage renal disease, but the shortage of cadaveric donors has increased reliance on living donors. Traditional open donor nephrectomy, while effective, is associated with significant morbidity. Hand-assisted laparoscopic donor nephrectomy (HALDN) combines the advantages of minimally invasive surgery with the tactile feedback of open surgery. This study presents the outcomes of HALDN procedures performed at the center.</p><p><strong>Methods: </strong>A total of 1221 living donor nephrectomies performed between September 2009 and August 2021 at Medicana !stanbul Hospital were analyzed. Donor characteristics, surgical details, and postoperative outcomes were recorded. Data analysis was conducted using SPSS version 22.0, with continuous variables assessed for normality and expressed accordingly.</p><p><strong>Results: </strong>Donor ages ranged from 19 to 87 years (mean 48.50 ± 12.75 years), with 54.8% female donors. The average body mass index (BMI) was 27.99 ± 3.7 kg/m2. Left-sided nephrectomies constituted 78.5% of cases, with HALDN performed in 94.7% of these surgeries. Warm ischemia time averaged 99.21 ± 56.67 seconds. The average blood loss was 70 mL, and the mean hospital stay was 4.12 ± 1.2 days. Complications included conversion to open surgery due to bleeding in 3.3% of cases, postoperative atelectasis (0.6%), incisional hernia (0.33%), wound infection (0.16%), and scrotal swelling (0.25%). The findings indicate that HALDN is a safe and effective method for donor nephrectomy, aligning with similar studies regarding operation and warm ischemia times. The minimally invasive nature of HALDN contributes to shorter hospital stays and quicker postoperative recovery. The rate of conversion to open surgery was within acceptable limits, and complications were manageable. Obesity (BMI > 30 kg/m2) was identified as a risk factor for incisional hernia, suggesting the need for careful surgical technique in this group.</p><p><strong>Conclusion: </strong>Hand-assisted laparoscopic donor nephrectomy offers a minimally invasive, safe, and effective alternative for living donor nephrectomy, enhancing donor recovery and potentially encouraging organ donation. Its adoption may play a signifi- cant role in reducing the number of patients awaiting organ transplants.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 6","pages":"355-358"},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015754/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is Partial Nephrectomy A Primary Option for Patients with T1b Renal Cell Carcinoma-A National Population-Based Study.","authors":"Sven Lundstam, Tarik Almdalal, Andreas Karlsson Rosenblad, Börje Ljungberg","doi":"10.5152/tud.2025.24081","DOIUrl":"https://doi.org/10.5152/tud.2025.24081","url":null,"abstract":"<p><strong>Objective: </strong>Renal cell carcinoma (RCC) patients in clinical T1 RCC generally exhibit a favorable prognosis. Guidelines recommend partial nephrectomy (PN), also for cT1b RCCs. Despite a favorable prognosis, there remains risks for upstaging and recurrence for cT1b RCC patients, and the preference for PN has been questionable. Clinical and morphological variables and overall survival (OS) were characterized in a national realworld population.</p><p><strong>Methods: </strong>Data from the the National Swedish Kidney Cancer Register 2005-2014, with non-metastatic cT1bRCC patients treated surgically and having !5 years potential follow-up were included (n = 2006). Patients gender, age, stage, tumor size, RCC type, local and distant tumor recurrence were evaluated.</p><p><strong>Results: </strong>Among 2006 patients (1219 males, 787 females; mean age 66 years), 1705 underwent radical nephrectomy (RN), and 301 PN. Upstage from cT1b to pathological T3a occurred in 304 (15%) patients. Recurrent disease was diagnosed in 318 (16%) patients, with higher rates in pT3a (25%) compared to pT1b (14%). There was no significant difference in disease recurrences observed between the surgical techniques. Factors associated with increased recurrence risk included age, T-stage, N-stage, and tumor size, while papillary and chromophobe RCCs were associated with decreased risk. Patients with pT3a RCC had a worse 5-year OS rate (67%) compared with pT1b (83%; P < .001, log-rank test). In adjusted analyses, age, tumor size, pT-stage, and pN- stage were associated with OS, while treatment with PN was non-inferior compared with RN (hazard ratio 0.91, 95% CI: 0.71-1.45, P = .431).</p><p><strong>Conclusion: </strong>Patients with clinical T1b RCCs face a non-negligible risk for tumor upstaging, disease recurrence, and decreased OS. The adjusted analyses showed that PN was non-inferior to RN, supporting the recommendation to offer PN.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 6","pages":"322-327"},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12015751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Study of the Efficacy and Tolerability of Palmex® (Roystonea regia Lipid Extract), Saw Palmetto, Finasteride and Tamsulosin in Patients with Benign Prostatic Hyperplasia.","authors":"Raúl Guzmán Mederos, Mónica Reyes Bello, Julio César Fernández Travieso, Manuel Pedroso Gastón, Sigfredo Calzadilla Feijoo, Miriam Hernández Rech, Maria de Los Angeles Viamontes Lu, Yenney Reyes Nuñez, Jilma Mena Figueroa, Zunilda Rodríguez Suárez, Lai López Rodríguez, Niurka Basulto Turran, Yolanda Cruz Gómez, Meilis Mesa Angarica, Sarahí Mendoza Castaño, Maytee Robaina García, Gladys Jiménez Rivero","doi":"10.5152/tud.2025.24067","DOIUrl":"https://doi.org/10.5152/tud.2025.24067","url":null,"abstract":"<p><strong>Objective: </strong>Evaluate and compare the efficacy and tolerability of the treatment with Palmex®, saw palmetto, finasteride, or tamsulosin administered for 6 months to patients with benign prostatic hyperplasia (BPH).</p><p><strong>Methods: </strong>This multicenter, open, prospective, comparative study was conducted in men !40 years with mild and moderate BPH according to the International Prostate Symptoms Score (IPSS) (!1, <19). The study included 200 patients (50 per group) who were randomly allocated to receive Palmex® (320 mg/d), saw palmetto (320 mg/d), finasteride (5 mg/d), or tamsulosin (0.4 mg/d). The primary study outcome was the improvement of the maximum urinary flow (Qmax), while significant decreases in IPSS values, prostate size, and residual post-voiding volume were secondary efficacy variables. Statistical analysis was performed according to Intention to treat.</p><p><strong>Results: </strong>The demographic baseline characteristics of all the groups were similar. All groups exhibited a significant mean increase in Qmax from baseline to week 24, being 3.8 mL/s (27.7%), 3.6 mL/s (23.1%), 4.2 mL/s (28.6%), and 4.1 mL/s (26.3%) on Palmex®, saw palmetto, finasteride, and tamsulosin, respectively. Likewise, all the treatments significantly reduced the IPSS scores by 74.2% (Palmex®), 74.6% (saw palmetto), 60.3% (finasteride), and 74.2% (tamsulosin), also decreasing the prostate size and the residual post-voiding volume. No significant differences among the groups were found regarding any efficacy variable. The treatments were well tolerated.</p><p><strong>Conclusion: </strong>Palmex® for 6 months demonstrated to have a comparable efficacy to saw palmetto, finasteride, and tamsulosin in patients with mild and moderate BPH, being safe and well tolerated.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 5","pages":"302-309"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Penile Girth and Length in the Erect State in Reassuring Patients with Small Penis Anxiety.","authors":"Sameh Fayek GamalEl Din, Nashaat Ismail Nabil, Mohamed A Khalil, Amgad Elseginy, Mohamed Ahmed AbdElSalam","doi":"10.5152/tud.2025.24133","DOIUrl":"https://doi.org/10.5152/tud.2025.24133","url":null,"abstract":"<p><strong>Objective: </strong>The present study examined the impact of measuring penile girth and length in the erect state on reassuring individuals with small penis anxiety (SPA) in the flaccid state.</p><p><strong>Methods: </strong>This study included 200 potent men aged 25-40 years old. All candidates were assessed by the validated Arabic version of the International Index of Erectile Function (ArIIEF-5), Hospital Anxiety and Depression Scale (HADS), Beliefs about Penile Size, and Cosmetic Procedure Screening questionnaires. Participants were divided into 100 healthy participants and 100 participants with SPA. We measured penile length and girth in the flaccid state in participants with SPA. After 2 weeks, we measured penile length and girth in the erect state by injecting 0.25 cc diluted prostaglandin E1 (PGE-1) in the corporeal bodies. Also, participants with SPA were reassessed by the ArIIEF-5 and the HADS in the erect state.</p><p><strong>Results: </strong>Penile length in the flaccid state was in the normal range 9.33 ± 0.81 cm that increased to 10.37 ± 0.89 cm in the erect state. The penile girth in the flaccid state was also in the normal range 8.08 ± 0.85 cm that increased to 9.33 ± 0.85 cm in the erect state. Significant decreases in the scores of HADS after PGE-1 injection were noted, denoting improvement in the patient's quality of life. The ArIIEF-5 score insignificantly increased after re-counseling in the erect state. Despite a significant reduction in anxiety and depression levels after re-counseling in the erect state, yet, they did not show any correlation with the penile dimensions in the flaccid and the erect states.</p><p><strong>Conclusion: </strong>Although the current study failed to demonstrate significant correlations between penile dimensions in the erect state and the ArIIEF-5 and the HADS scores. Yet, there was significant decrease in HADS score and insignificant increase in ArIIEF-5 score denoting that men with SPA should be counseled in the erect state.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 5","pages":"316-321"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Systematic Review and Meta-Analysis of Penis Length and Circumference According to WHO Regions: Who has the Biggest One?","authors":"Hadi Mostafaei, Keiichiro Mori, Satoshi Katayama, Fahad Quhal, Benjamin Pradere, Takafumi Yanagisawa, Ekaterina Laukhtina, Frederik König, Reza Sari Motlagh, Pawel Rajwa, Hanieh Salehi-Pourmehr, Sakineh Hajebrahimi, Shahrokh F Shariat","doi":"10.5152/tud.2025.24038","DOIUrl":"https://doi.org/10.5152/tud.2025.24038","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to perform a systematic review and meta-analysis of stretched, erect, and flaccid penis length as well as circumference according to geographic WHO regions.</p><p><strong>Methods: </strong>PubMed, Embase, Scopus, and Cochrane Library were searched for articles published until February 2024. Studies in which a healthcare professional evaluated the penis size were considered eligible. After assessing the risk of bias, a systematic review and meta-analyses were performed according to the Preferred Reporting Items for Systematic Review and Meta-analysis statement, and the outcomes were grouped based on the WHO regions.</p><p><strong>Results: </strong>A total of 33 studies comprising 36 883 patients were included. The risk of bias in the included studies was moderate/low. A comprehensive systematic review was done and meta-analyses performed for flaccid length [n = 28 201, mean (SE) 9.22 (0.24) cm], stretched length [n = 20 814, mean (SE) 12.84 (0.32) cm], erect length [n = 5669, mean (SE) 13.84 (0.94) cm], flaccid circumference [n = 30 117, mean (SE) 9.10 (0.12) cm], and erect circumference [n = 5168, mean (SE) 11.91 (0.18) cm]. The mean length of the stretched penis was largest in Americans [14.47 (0.90) cm]. The mean length of the flaccid penis was the largest in the Americas [10.98 (0.064) cm]. The mean flaccid penile circumference was largest in Americans [n = 29 714, mean (SE) 10.00 (0.04) cm].</p><p><strong>Conclusions: </strong>Penis sizes vary across WHO regions, suggesting the need to adjust standards according to geography to better understand councilmen and their partners. These data provide a framework for discussing body image expectations and therapeutic strategies in this sensitive and emotional subject matter.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 5","pages":"291-301"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144003488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison on Surgical Outcomes of Mini-Versus Standard-Percutaneous Nephrolithotomy in Staghorn Calculi: A Systematic Review and Meta-Analysis.","authors":"Noka Yogahutama, Muhammad Isa Fuad Affan, Alan Primi Ladese, Nicholas Abraham","doi":"10.5152/tud.2025.24125","DOIUrl":"https://doi.org/10.5152/tud.2025.24125","url":null,"abstract":"<p><p>Percutaneous Nephrolithotomy (PCNL) has become the standard for managing staghorn calculi. Smaller access sheath Mini-PCNL (M-PCNL) has been known for its advantages in surgical outcomes compared with Standard-PCNL (S-PCNL) in various settings. We conducted this systematic review to compare surgical outcomes and postoperative complications of M-PCNL vs. S-PCNL in staghorn calculi treatment. A systematic search of the literature was performed on PubMed, Cochrane Library, ProQuest, Scopus, ClinicalTrials.gov, and Google Scholar according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement (PRISMA Statement). Five randomized controlled trial (RCT) and 5 cohort studies were included. Risk of bias assessment was evaluated using Cochrane risk of bias (RoB) 2 and Cochrane RoB in Nonrandomized Studies - of Interventions (ROBINS-I). Ten studies involving 1733 staghorn calculi patients met the inclusion criteria. The stone-free rate (SFR) was comparable (odds ratio (OR) 1.13, 95% CI: 0.90-1.43, P = .28) compared to S-PCNL. Pooled analysis showed that M-PCNL resulted in a significantly lower shorter operative time (mean differences (MD) 14.06, 95% CI: 6.09-22.03, P < .001), lower blood transfusion (OR 0.46, 95% CI: 0.29-0.72, P < .001), and lower hemoglobin drop (MD !0.37, 95% CI: !0.72 to !0.03, P = .03) compared to S-PCNL. This meta-analysis suggests that while M-PCNL has comparable SFR to S-PCNL, it offers benefits in terms of shorter operative time, reduced blood transfusion needs, and less hemoglobin drop.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 5","pages":"281-290"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of Bladder Microbiota in Female Patients with Overactive Bladder Syndrome.","authors":"Esra Kaya, Tayfun Sahınkanat, Murat Aral","doi":"10.5152/tud.2025.24040","DOIUrl":"https://doi.org/10.5152/tud.2025.24040","url":null,"abstract":"<p><strong>Objective: </strong>With the demonstration that the bladder is not sterile, the relationship between bladder microbiota and urinary system diseases has begun to be investigated. The aim of our study is to investigate the relationship between overactive bladder (OAB) syndrome and bladder microbiota.</p><p><strong>Methods: </strong>A total of 20 OAB syndrome patients and 20 controls were included in the study. Urine samples were taken with a transurethral catheter. We developed a modified expanded quantitative urine culture method and inoculated them into anaerobic blood culture bottles and thioglycolate medium at the bedside. The MALDI-TOF MS system was used for bacterial identification.</p><p><strong>Results: </strong>Thirty-five bacteria were identified in the patient group and 30 in the control group. As a result of culture, 16 different genera and 29 different types of bacteria were identified. Staphylococcus (25.7%) was the most common bacterial genus in the patient group, followed by Streptococcus (17.1%) and Lactobacillus (14.3%). Lactobacillus (26.7%) was the most frequently detected bacterial genus in the control group, followed by Streptococcus (13.3%) and Enterococcus (13.3%). The rate of Staphylococcus epidermidis in the patient group (22.9%) was found to be significantly higher than in the control group (0%) (P = .006). In the patient group, Lactobacillus gasseri's incidence (2.9%) was found to be significantly lower than in the control group (20.0%) (P = .042).</p><p><strong>Conclusion: </strong>Our study shows that patients with OAB have a significantly different microbiota compared to the control group.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 5","pages":"310-315"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923597/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144014084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Freehand Transperineal Prostate Biopsy Improves the Detection Rate of Clinically Significant Prostate Cancer.","authors":"Juan Manuel Bujaldon, Gonzalo Juan Vitagliano, Leandro Blas, Martin Maqueda Vocos, Hernando Rios Pita","doi":"10.5152/tud.2025.24026","DOIUrl":"https://doi.org/10.5152/tud.2025.24026","url":null,"abstract":"<p><strong>Objective: </strong>Freehand transperineal prostate biopsy (fTP-Bx) has been established as an alternative within the transperineal approach for prostate cancer (CaP) diagnosis. The primary objective was to compare the rate of overall CaP detection and clinically significant (greater than or equal to International Society of Urological Pathology 2) in patients with biopsy-naive between freehand transperineal prostate biopsy (fTP-Bx) and transperineal grid biopsy (TP-Bx) techniques. The secondary objective was to show the characteristics of the procedure and measure the associated complications.</p><p><strong>Methods: </strong>A retrospective review of all patients who underwent fTP-Bx (n: 326) and TP-Bx (n: 118) in our department was conducted between October 2020 and May 2023 due to suspected CaP based on elevated prostate-specific antigen (PSA), suspicious digital rectal examination, or those under active surveillance protocol. The chisquare test and Fisher's exact test were used to compare categorical variables.</p><p><strong>Results: </strong>A retrospective review of all patients who underwent fTP-Bx (n: 326) and TP-Bx (n: 118) in our department was conducted between October 2020 and May 2023 due to suspected CaP based on elevated prostate-specific antigen (PSA), suspicious digital rectal examination, or those under active surveillance protocol. The chisquare test and Fisher's exact test were used to compare categorical variables.</p><p><strong>Conclusion: </strong>Freehand transperineal prostate biopsy achieved a higher rate of clinically significant CaP detection than TP-Bx in biopsy-naive patients, accompanied by a lower number of postoperative complications.</p>","PeriodicalId":101337,"journal":{"name":"Urology research & practice","volume":"50 5","pages":"269-274"},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11923604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144063689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}