DevicePub Date : 2025-03-06DOI: 10.1016/j.device.2025.100724
Engui Wang, Maosheng Wu, Lin Luo, Xi Cui, Lingling Xu, Ruizeng Luo, Yang Zou, Le Tian, Yizhu Shan, Yichang Quan, Yuan Bai, Li Wu, Yiran Hu, Sijing Cheng, J. C. Yang, Chang Zhu, Dengjie Yu, Jianying Ji, Yi Ren, Dongjie Jiang, Bojing Shi, Hongqing Feng, Wei Hua, Zhou Li, Han Ouyang
{"title":"Symbiotic biodegradable flexible supercapacitor in vivo","authors":"Engui Wang, Maosheng Wu, Lin Luo, Xi Cui, Lingling Xu, Ruizeng Luo, Yang Zou, Le Tian, Yizhu Shan, Yichang Quan, Yuan Bai, Li Wu, Yiran Hu, Sijing Cheng, J. C. Yang, Chang Zhu, Dengjie Yu, Jianying Ji, Yi Ren, Dongjie Jiang, Bojing Shi, Hongqing Feng, Wei Hua, Zhou Li, Han Ouyang","doi":"10.1016/j.device.2025.100724","DOIUrl":"https://doi.org/10.1016/j.device.2025.100724","url":null,"abstract":"Publisher of over 50 scientific journals across the life, physical, earth, and health sciences, both independently and in partnership with scientific societies including Cell, Neuron, Immunity, Current Biology, AJHG, and the Trends Journals.","PeriodicalId":101324,"journal":{"name":"Device","volume":"3 6","pages":"100724-100724"},"PeriodicalIF":0.0,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147886253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DevicePub Date : 2025-01-17Epub Date: 2025-01-09DOI: 10.1016/j.device.2024.100676
Yichong Ren, Feng Zhang, Zheng Yan, Pai-Yen Chen
{"title":"Wearable bioelectronics based on emerging nanomaterials for telehealth applications.","authors":"Yichong Ren, Feng Zhang, Zheng Yan, Pai-Yen Chen","doi":"10.1016/j.device.2024.100676","DOIUrl":"https://doi.org/10.1016/j.device.2024.100676","url":null,"abstract":"<p><p>Nanomaterial-driven, soft wearable bioelectronics are transforming telemedicine by offering skin comfort, biocompatibility, and the capability for continuous remote monitoring of physiological signals. The devices, enabled by advanced zero-dimensional (0D), one-dimensional (1D), and two-dimensional (2D) nanomaterials, have achieved new levels in electrical stability and reliability, allowing them to perform effectively even under dynamic physical conditions. Despite their promise, significant challenges remain in the fabrication, integration, and practical deployment of nanoscale materials and devices. Critical challenges include ensuring the durability and stability of nanomaterial-based bioelectronics for extended wear and developing efficient integration strategies to support multifunctional sensing modalities. Telemedicine has revolutionized healthcare by enabling remote health monitoring. The integration of nanomaterials within wearable devices is a central factor driving this breakthrough, as these materials enhance sensor sensitivity, durability, and multifunctionality. These wearable sensors leverage various operating principles tailored to specific applications, such as intraocular pressure monitoring, electrophysiological signal recording, and biochemical marker tracking.</p>","PeriodicalId":101324,"journal":{"name":"Device","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11981230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DevicePub Date : 2025-01-09DOI: 10.1016/j.device.2024.100658
Chunjiang Wang, Xiaoming Chen, Qihang Song, Jianxu Shi, Mengyong Lei, Duo Ma, Xiangming Li, Xiaoliang Chen, Hongmiao Tian, Chunhui Wang, Jie Zhang, Yang Lü, Jinyou Shao
{"title":"Investment micro-casting 3D-printed multi-metamaterial for programmable multimodal biomimetic electronics","authors":"Chunjiang Wang, Xiaoming Chen, Qihang Song, Jianxu Shi, Mengyong Lei, Duo Ma, Xiangming Li, Xiaoliang Chen, Hongmiao Tian, Chunhui Wang, Jie Zhang, Yang Lü, Jinyou Shao","doi":"10.1016/j.device.2024.100658","DOIUrl":"https://doi.org/10.1016/j.device.2024.100658","url":null,"abstract":"Biometric electronics have gained considerable attention in self-sensing, three-dimensional (3D) designs, mechanical drive, and multi-function integration. By leveraging these anisotropic capabilities into devices, metamaterial offers a promising pathway to exciting performance-oriented units. However, such distinctive mismatches in forming processes and inherent material properties are severely restricted in achieving cross-scaled microstructures, causing compatibility issues among well-defined bio-functions and fabrication. Herein, we propose an investment micro-casting 3D printing strategy for custom-molding multi-metamaterials without process barriers. This approach handles the bottlenecks of the hierarchical template replacement in ultra-hydrophobicity microchannels for the free assembly of more than 20 types of challenging-to-form materials. A series of piezoelectric metamaterials are programmed with broadband ranges, imitating nerve distribution that has human-feel touch, bending, and recognition. Our work benefits the stiffness self-perception in dynamic grabbing manipulation, broadening the application of multimodal electronics in bio-embodied robots.","PeriodicalId":101324,"journal":{"name":"Device","volume":"3 5","pages":"100658-100658"},"PeriodicalIF":0.0,"publicationDate":"2025-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147895498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DevicePub Date : 2024-12-20Epub Date: 2024-08-21DOI: 10.1016/j.device.2024.100514
Ian R Woodward, Yinkui Yu, Catherine A Fromen
{"title":"Experimental Full-volume Airway Approximation for Assessing Breath-dependent Regional Aerosol Deposition.","authors":"Ian R Woodward, Yinkui Yu, Catherine A Fromen","doi":"10.1016/j.device.2024.100514","DOIUrl":"10.1016/j.device.2024.100514","url":null,"abstract":"<p><p>Modeling aerosol dynamics in the airways is challenging, and most modern personalized <i>in vitro</i> tools consider only a single inhalation maneuver through less than 10% of the total lung volume. Here, we present an <i>in vitro</i> modeling pipeline to produce a device that preserves patient-specific upper airways while approximating deeper airways, capable of achieving total lung volumes over 7 liters. The modular system, called TIDAL, includes tunable inhalation and exhalation breathing capabilities with resting flow rates up to 30 liters per minute. We show that the TIDAL system is easily coupled with industrially and clinically relevant devices for aerosol therapeutics. Using a vibrating mesh nebulizer, we report central-to-peripheral (C:P) aerosol deposition measurements aligned with both <i>in vivo</i> and <i>in silico</i> benchmarks. These findings underscore the effectiveness of the TIDAL model in predicting airway deposition dynamics for inhalable therapeutics.</p>","PeriodicalId":101324,"journal":{"name":"Device","volume":"2 12","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11671099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142904712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DevicePub Date : 2024-11-15Epub Date: 2024-10-24DOI: 10.1016/j.device.2024.100596
Saehyun Kim, Ethan Eig, Jiping Yue, Albert Yang, Colin J Comerci, Megan Laune, Chuanwang Yang, Ananth Kamath, Jiuyun Shi, Pengju Li, Zhe Cheng, Changxu Sun, Tiantian Guo, Vanessa Tian, Gürol M Süel, Bozhi Tian
{"title":"Bioelectronic Drug-free Control of Opportunistic Pathogens through Selective Excitability.","authors":"Saehyun Kim, Ethan Eig, Jiping Yue, Albert Yang, Colin J Comerci, Megan Laune, Chuanwang Yang, Ananth Kamath, Jiuyun Shi, Pengju Li, Zhe Cheng, Changxu Sun, Tiantian Guo, Vanessa Tian, Gürol M Süel, Bozhi Tian","doi":"10.1016/j.device.2024.100596","DOIUrl":"10.1016/j.device.2024.100596","url":null,"abstract":"<p><p>The natural excitability in mammalian tissues has been extensively exploited for drug-free electroceutical therapies. However, it is unclear whether bacterial residents on the human body are equally excitable and if their excitability can also be leveraged for drug-free bioelectronic treatment. Using a microelectronic platform, we examined the electrical excitability of <i>Staphylococcus epidermidis</i>, a skin-residing bacterium responsible for widespread clinical infections. We discovered that a non-lethal electrical stimulus could excite <i>S. epidermidis</i>, inducing reversible changes in membrane potential. Intriguingly, <i>S. epidermidis</i> became excitable only under acidic skin pH, indicating that the bacteria were 'selective' about the environment in which they display excitability. This selective excitability enabled programmable suppression of biofilm formation using benign stimulation voltages. Lastly, we demonstrated suppression of <i>S. epidermidis</i> on a porcine skin model using a flexible electroceutical patch. Our work shows that the innate excitability of resident bacteria can be selectively activated for drug-free bioelectronic control.</p>","PeriodicalId":101324,"journal":{"name":"Device","volume":"2 11","pages":""},"PeriodicalIF":8.7,"publicationDate":"2024-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124811/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}