Device最新文献 - Book学术

Experimental Full-volume Airway Approximation for Assessing Breath-dependent Regional Aerosol Deposition. 评估呼吸依赖区域气溶胶沉积的实验全体积气道近似。

Device Pub Date : 2024-12-20 Epub Date: 2024-08-21 DOI: 10.1016/j.device.2024.100514

Ian R Woodward, Yinkui Yu, Catherine A Fromen

引用次数: 0

An implantable system for opioid safety. 阿片类药物安全的植入式系统。

Device Pub Date : 2024-10-18 Epub Date: 2024-08-14 DOI: 10.1016/j.device.2024.100517

Hen-Wei Huang, Peter R Chai, Seungho Lee, Tom Kerssemakers, Ali Imani, Jack Chen, Marco Heim, Jessica Y Bo, Adam Wentworth, Fokion T Sanoudos-Dramaliotis, Ian Ballinger, Saurav Maji, Matt Murphy, Alexander Alexiev, Gloria H Kang, Niora Fabian, Josh Jenkins, Andrew Pettinari, Keiko Ishida, Jason Li, Siheng Sean You, Alison M Hayward, Anantha Chandrakasan, Giovanni Traverso

{"title":"An implantable system for opioid safety.","authors":"Hen-Wei Huang, Peter R Chai, Seungho Lee, Tom Kerssemakers, Ali Imani, Jack Chen, Marco Heim, Jessica Y Bo, Adam Wentworth, Fokion T Sanoudos-Dramaliotis, Ian Ballinger, Saurav Maji, Matt Murphy, Alexander Alexiev, Gloria H Kang, Niora Fabian, Josh Jenkins, Andrew Pettinari, Keiko Ishida, Jason Li, Siheng Sean You, Alison M Hayward, Anantha Chandrakasan, Giovanni Traverso","doi":"10.1016/j.device.2024.100517","DOIUrl":"10.1016/j.device.2024.100517","url":null,"abstract":"Naloxone can effectively rescue victims from opioid overdose, but less than 5% survive due to delayed or absent first responder intervention. Current overdose reversal systems face key limitations, including low user adherence, false positive detection, and slow antidote delivery. Here, we describe a subcutaneously implanted robotic first responder to overcome these challenges. This implantable system for opioid safety continuously monitors vital signs, detecting opioid overdose through an algorithm analyzing the interplay of cardiorespiratory responses. To address battery concerns with continuous monitoring and multi-sensing modality, an adaptive algorithm dynamically adjusts sensor resolution, reducing the need for frequent charging. Furthermore, the implant includes an ultra-rapid naloxone delivery pump, delivering the 10-mg antidote within 10 s. In animal trials, the robotic first responder successfully revived 96% of overdosed pigs (n = 25) within 3.2 min, showcasing its potential to dramatically improve survival rates and combat the opioid epidemic.","PeriodicalId":101324,"journal":{"name":"Device","volume":"2 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11735030/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A magnetically controlled soft robotic glove for hand rehabilitation.

Device Pub Date : 2024-09-20 Epub Date: 2024-08-22 DOI: 10.1016/j.device.2024.100512

Leah T Gaeta, M Deniz Albayrak, Lorenzo Kinnicutt, Susanna Aufrichtig, Pranav Sultania, Hanna Schlegel, Terry D Ellis, Tommaso Ranzani

{"title":"A magnetically controlled soft robotic glove for hand rehabilitation.","authors":"Leah T Gaeta, M Deniz Albayrak, Lorenzo Kinnicutt, Susanna Aufrichtig, Pranav Sultania, Hanna Schlegel, Terry D Ellis, Tommaso Ranzani","doi":"10.1016/j.device.2024.100512","DOIUrl":"10.1016/j.device.2024.100512","url":null,"abstract":"For individuals with hand motor function losses, rehabilitation is necessary for regaining strength and range of motion to accomplish daily activities. Typically within a clinical setting, repetitive strength-based and task-specific exercises are prescribed. However, these therapies are generally costly and non-portable, limiting patient accessibility and rendering patient compliance impractical. There is thus a clinical need for a system that is low-cost, portable, and accessible to improve patient compliance and outcomes. This work presents a proof-of-concept magnetically-controlled glove to provide targeted resistance-based rehabilitation for patients with hand motor impairments. The glove is inexpensive, customizable, and portable, allowing for use within a clinic and at home. Customizable resistance is achieved by electropermanent magnets (EPMs), which locally control magnetic attraction of the digits and produce rapid stiffness changes from magnetically induced jamming. Various rehabilitative exercises using the glove are demonstrated and the magnetic fields can be customized to provide necessary resistance.","PeriodicalId":101324,"journal":{"name":"Device","volume":"2 9","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11864777/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143525765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemical pneumatic battery for untethered robotics 用于非系留机器人的电化学气动蓄电池

Device Pub Date : 2024-07-01 DOI: 10.1016/j.device.2024.100460

Junyu Ge, Yuchen Zhao, Yifan Wang, Hong Li