DevicePub Date : 2025-08-19DOI: 10.1016/j.device.2025.100893
Y. Ming, Chunyu Zhang, Xi Kang, Xiaolong Wang, J. J. Xu, Shengnan Liang, Dawen Zeng
{"title":"Iontronic sensor based on multiphase design for weak dynamic pressure decoding and intelligent interactive system","authors":"Y. Ming, Chunyu Zhang, Xi Kang, Xiaolong Wang, J. J. Xu, Shengnan Liang, Dawen Zeng","doi":"10.1016/j.device.2025.100893","DOIUrl":"https://doi.org/10.1016/j.device.2025.100893","url":null,"abstract":"","PeriodicalId":101324,"journal":{"name":"Device","volume":"3 10","pages":"100893-100893"},"PeriodicalIF":0.0,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147911029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DevicePub Date : 2025-08-15DOI: 10.1016/j.device.2025.100774
Mona A Mohamed, Sina Khazaee Nejad, Haozheng Ma, Abdulrahman Al-Shami, Melissa Banks, Ali Soleimani, Victor Ong, Daniel Vargas Ramos, Maral P S Mousavi
{"title":"Safer breastfeeding with a wearable sensor for monitoring maternal acetaminophen transfer through breast milk.","authors":"Mona A Mohamed, Sina Khazaee Nejad, Haozheng Ma, Abdulrahman Al-Shami, Melissa Banks, Ali Soleimani, Victor Ong, Daniel Vargas Ramos, Maral P S Mousavi","doi":"10.1016/j.device.2025.100774","DOIUrl":"10.1016/j.device.2025.100774","url":null,"abstract":"<p><p>Acetaminophen is the most prescribed medication for the management of postpartum pain as well as infant fever. Medications taken by breastfeeding mothers are released into the breast milk at different levels, creating concern for indirect infant exposure to acetaminophen through milk. This work develops a new tool for rapid, direct, and quantitative measurement of acetaminophen in breast milk. We have developed an innovative wearable device for milk sampling and analysis by integrating microfluidic channels and flexible laser-induced graphene sensors into a lactation pad. The fabrication process for the flexible sensors has been optimized using a rotatable central composite design. The wearable sensor achieves high sensitivity to acetaminophen in a large dynamic range of 10-600 μM, providing a promising tool for preventing acetaminophen toxicity in nursing mothers and breastfed infants. This device fills a healthcare gap, advancing breast milk analysis.</p>","PeriodicalId":101324,"journal":{"name":"Device","volume":"3 8","pages":""},"PeriodicalIF":8.7,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12806175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146000393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DevicePub Date : 2025-07-18DOI: 10.1016/j.device.2025.100727
Cooper P Thome, Creighton T Tisdale, C Wyatt Shields
{"title":"Siphon-based multichannel acoustofluidic separator for rapid and multiplexed biomolecule detection.","authors":"Cooper P Thome, Creighton T Tisdale, C Wyatt Shields","doi":"10.1016/j.device.2025.100727","DOIUrl":"10.1016/j.device.2025.100727","url":null,"abstract":"<p><p>Conventional strategies for biological sensing require complex workflows to capture, isolate, and prepare biomolecules for specific and high-sensitivity detection. Instruments that facilitate these processes are usually cumbersome, reducing user-friendliness and accessibility. Here, we present a multichannel acoustic separator with biospecific and acoustically responsive microparticles to simplify workflows and shorten the time needed to isolate and detect biomarkers from complex fluids. The multichannel acoustic separator is 3D-printed and supports 12 acoustofluidic trapping channels that isolate the biospecific particles from off-target contaminants in the fluid. Fluid flow through the channels is driven by a semi-continuous siphon, which eliminates the need for fluid pumps. We tested the system for purifying three disparate biomolecules in individual and multiplexed formats, as well as the purification of IgA from whole blood for detection in approximately 70 min.</p>","PeriodicalId":101324,"journal":{"name":"Device","volume":"3 7","pages":""},"PeriodicalIF":8.7,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13008365/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147518112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DevicePub Date : 2025-07-15DOI: 10.1016/j.device.2025.100843
Xueqing Yang, Junwei Liu, Zhihua Zhou, Yan Liang, Junjiang Wu, Saimeng Li, Dexia Han, Yahui Du, Zhiling Guo, Yu Chen, Long Ye, Jinyue Yan
{"title":"Enhancing year-round photovoltaic performance using the dual cooling and warming functions of hydrogels","authors":"Xueqing Yang, Junwei Liu, Zhihua Zhou, Yan Liang, Junjiang Wu, Saimeng Li, Dexia Han, Yahui Du, Zhiling Guo, Yu Chen, Long Ye, Jinyue Yan","doi":"10.1016/j.device.2025.100843","DOIUrl":"https://doi.org/10.1016/j.device.2025.100843","url":null,"abstract":"","PeriodicalId":101324,"journal":{"name":"Device","volume":"3 10","pages":"100843-100843"},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147893573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DevicePub Date : 2025-06-20Epub Date: 2025-02-27DOI: 10.1016/j.device.2025.100715
Li Zhan, Hunter Hinnen, Kaustav A Gopinathan, Mehmet Toner
{"title":"Autonomous cryoprotectant loading of the oocyte using microfluidic transistors.","authors":"Li Zhan, Hunter Hinnen, Kaustav A Gopinathan, Mehmet Toner","doi":"10.1016/j.device.2025.100715","DOIUrl":"https://doi.org/10.1016/j.device.2025.100715","url":null,"abstract":"<p><p>Oocyte cryopreservation is a critical step of <i>in vitro</i> fertilization (IVF). The handling and loading of cryoprotectant currently rely on manual pipetting methods, which leads to outcome variations, high cost and limited accessibility. Here we developed a low-cost and user-friendly microfluidic device to automate the complex multistep process of oocyte CPA loading, delivering cryopreservation-ready oocytes. We utilized microfluidic transistors to create fluidic timers and logic gates, which generated time-dependent pressure signals to control the embedded valves, thereby regulating the flow conditions over the oocyte. Using constant pressure supplies, we demonstrated autonomous mouse oocyte trapping, linear loading of equilibrium solution, dehydration with vitrification solution and oocyte extraction from the device. Our work represents an important step towards autonomous IVF-on-a-chip to enhance the accessibility and affordability of IVF.</p>","PeriodicalId":101324,"journal":{"name":"Device","volume":"3 6","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12366841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DevicePub Date : 2025-05-22DOI: 10.1016/j.device.2025.100804
Rémy A Furrer, Amanda R Merner, Ian Stevens, Peter Zuk, Theresa Williamson, Francis X Shen, Gabriel Lázaro-Muñoz
{"title":"Public Perceptions of Neurotechnologies Used to Target Mood, Memory, and Motor Symptoms.","authors":"Rémy A Furrer, Amanda R Merner, Ian Stevens, Peter Zuk, Theresa Williamson, Francis X Shen, Gabriel Lázaro-Muñoz","doi":"10.1016/j.device.2025.100804","DOIUrl":"10.1016/j.device.2025.100804","url":null,"abstract":"<p><p>Public attitudes toward four neurotechnologies for treating three types of brain disorders (mood, motor, and memory) vary on a range of metrics such as perceived risk, invasiveness, and likelihood of use. In a survey of 1,052 U.S. participants, deep brain stimulation (DBS) was seen as the most invasive and risky among the surveyed methods, involving the greatest perceived change to the person and the least likely to be used personally. Non-surgical options like transcranial magnetic stimulation (TMS) and pills were viewed as more acceptable. Devices targeting motor symptoms were rated as more beneficial and acceptable than those for mood or memory. These findings highlight barriers to adoption and the need to address public perceptions, ensure patients are informed, and promote ethical implementation of these technologies.</p>","PeriodicalId":101324,"journal":{"name":"Device","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12419521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
DevicePub Date : 2025-04-18Epub Date: 2025-01-17DOI: 10.1016/j.device.2024.100660
Corey M Efaw, Zihan Wang, Hongxing Zhang, Pete L Barnes, Leidong Xu, Yulong Wang, Daniel Olds, Sangwook Kim, Bumjun Park, Aashray Narla, Hui Xiong, Eric J Dufek, Peter G Khalifah, Hongyi Xu, Bin Li
{"title":"Pressure effects on lithium anode/nickel-manganese-cobalt oxide cathode pouch cells through fixture design.","authors":"Corey M Efaw, Zihan Wang, Hongxing Zhang, Pete L Barnes, Leidong Xu, Yulong Wang, Daniel Olds, Sangwook Kim, Bumjun Park, Aashray Narla, Hui Xiong, Eric J Dufek, Peter G Khalifah, Hongyi Xu, Bin Li","doi":"10.1016/j.device.2024.100660","DOIUrl":"10.1016/j.device.2024.100660","url":null,"abstract":"<p><p>Applying external pressure to a pouch cell results in improved performance, implicating systems-level design of batteries. Here, different formats and amounts of external pressure to Li-Li<sub>x</sub>Ni<sub>0.8</sub>Mn<sub>0.1</sub>Co<sub>0.1</sub>O<sub>2</sub> (Li-NMC811) pouch cells were studied under lean electrolyte conditions. Due to the more uniform lithium plating/stripping, a constant gap fixture that retains the distance of the frame during cycling performed greater than a constant pressure fixture that retains applied pressure to the cell. In addition, the use of flexible foam in a constant gap fixture revealed enhanced cycle life at 10 psi; however, at 30 psi, the use of a rigid plate extended cycle life to over 250 cycles, while the foam severely shortened cycle life. This discrepancy with pressure was proven to be driven by stress distribution on cell components. The failure mechanisms and the effects of pressure fixture design on cell components were unveiled, shedding light on improving high-energy battery performance through at-scale fixture design.</p>","PeriodicalId":101324,"journal":{"name":"Device","volume":"3 4","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12393160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144985092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}