Journal of the Indian Society of Pedodontics and Preventive Dentistry最新文献

{"title":"Comparison of smart burs and chemo-mechanical caries removal systems in primary molars - A systematic review and meta-analysis.","authors":"Deepshikha Mehrotra, Sanjana R Kodical, Shilpa Shetty Naik","doi":"10.4103/jisppd.jisppd_308_24","DOIUrl":"https://doi.org/10.4103/jisppd.jisppd_308_24","url":null,"abstract":"<p><strong>Background: </strong>Smart burs and chemo-mechanical caries removal (CMCR) systems are considered viable alternatives to traditional cavity preparation techniques. Numerous clinical studies have been conducted to assess and compare the impact of these two techniques; nevertheless, these studies have demonstrated considerable variability in their findings. The objectives of the present systematic review and meta-analysis were to compare the efficacy, efficiency, and patient comfort of CMCR systems and smart burs in primary molars.</p><p><strong>Methodology: </strong>The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis 2020 guidelines. Ten electronic databases up to May 30, 2024 were searched for in vivo clinical studies comparing at least one CMCR system with smart burs in terms of clinical and/or microbiological efficacy, efficiency (time taken for complete caries removal), and patient comfort in primary molars. Reviews, abstracts, case series and reports, letters to the editor, animal studies, and unpublished data were excluded. The risk of bias (ROB) assessment was conducted using the ROBINS-I and Cochrane ROB tools for nonrandomized and randomized clinical studies, respectively. The analysis was performed using Review Manager version 5.4.1 provided by the Cochrane Collaboration. The standardized mean difference served as the summary with a random effects model (P < 0.05).</p><p><strong>Results: </strong>A total of 154 studies were identified and screened out of which five were included in the qualitative synthesis and four studies were deemed suitable for a meta-analysis. The overall quality assessment revealed a presence of moderate-to-low ROB. The data extracted from the five studies were tabulated. The summary odds ratio for clinical efficacy (0.43 [95% confidence interval (CI) = 0.13-1.49]) showed no statistically significant difference between CMCR systems and Smart burs (Z = 1.33 and P = 0.18). A statistically significant difference ([Z = 5.85 and P < 0.00001] and [Z = 2.84 and P = 0.005]) in terms of microbiological efficacy (446.46 [95% CI = 296.89-596.02]) and efficiency (-0.68 [95% CI = -1.16--0.21]) was observed between CMCR systems and smart burs. Smart burs performed better in terms of microbiological efficacy and efficiency. Due to variability in the scales used to evaluate patient comfort, meta-analysis was not possible.</p><p><strong>Conclusion: </strong>Within the limitations of this study, Smart burs performed better in terms of microbiological efficacy and efficiency and hence can be used as an alternative to CMCR systems in primary molars.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"42 4","pages":"257-266"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142974168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the efficacy of cavity disinfection using methylene blue dye with 660-nm diode laser on primary molars: An in vivo study.","authors":"Mitaj Pandharinath Anvekar, Shruti Girish Virupaxi, Chandrashekar Yavagal, Sadanand Kulkarni, Ramya Pai, Viplavi Vijaysinh Chavan Patil","doi":"10.4103/jisppd.jisppd_258_24","DOIUrl":"https://doi.org/10.4103/jisppd.jisppd_258_24","url":null,"abstract":"<p><strong>Background and objectives: </strong>The purpose of this study was to evaluate the antimicrobial activity of methylene blue dye with 660-nm diode laser in cavity disinfection and to compare the total bacterial count in dentinal samples preexcavation, postexcavation, and postdisinfection. The study design was experimental in vivo.</p><p><strong>Materials and methods: </strong>Fifteen children aged 5-12 years with 15 primary molars requiring atraumatic restorative treatment (ART) were selected. Dentinal samples were collected from the carious tooth with a sterile spoon excavator three times, i.e., before caries excavation (preexcavation), after hand excavation of caries (postexcavation), and after doing laser photodynamic therapy with methylene blue dye and 660-nm diode laser (postdisinfection) and sent for microbiological analysis. The samples were transported in reduced transport fluid. The total bacterial count was carried out by an experienced microbiologist immediately after reporting.</p><p><strong>Results: </strong>A significant number of bacteria was present after hand excavation of caries using ART. The bacterial count significantly reduced postlaser disinfection. The total viable bacterial count was reduced to 87.17% with hand excavation of caries, whereas it was reduced to 98.59% postlaser disinfection using methylene blue dye with 660-nm diode laser.</p><p><strong>Conclusion: </strong>It was seen that ART cannot eliminate all the microorganisms. Methylene blue dye with a 660-nm diode laser was able to reduce the total bacterial count and can be effectively used as an antimicrobial cavity disinfectant.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"42 4","pages":"280-285"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142974194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The third-wave society!","authors":"Sharath Asokan","doi":"10.4103/jisppd.jisppd_529_24","DOIUrl":"https://doi.org/10.4103/jisppd.jisppd_529_24","url":null,"abstract":"","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"42 4","pages":"255-256"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142974216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of EndoActivator, PATS Vario system, and XP-endo Finisher files on smear layer removal under scanning electron microscope: A comparative study.","authors":"Rishabh Patel, Gaurav Shinde, Prashant Bondarde, Aruna Vishwakarma, Madhuri Bhandare, Vaibhavi Pharne","doi":"10.4103/jisppd.jisppd_233_24","DOIUrl":"10.4103/jisppd.jisppd_233_24","url":null,"abstract":"<p><strong>Context: </strong>The smear layer may harbor many bacteria; hence, alternative methods are used to disrupt and remove biofilm.</p><p><strong>Aim: </strong>The aim of the study was to compare the effectiveness of EndoActivator, PATS Vario System, and XP-endo Finisher files on smear layer removal using a scanning electron microscope.</p><p><strong>Subjects and methods: </strong>Sixty single-rooted extracted premolars with Vertucci Type 1 configuration were decoronated and divided into four groups. The groups were instrumented with the rotary ProTaper file system. All specimens were flushed with 1 ml of 3% sodium hypochlorite. Group 1 was irrigated with a conventional needle and syringe. In Group 2, the irrigant was activated with an EndoActivator. In Group 3, the irrigant was activated with PATS Vario system, and in Group 4, XP-endo Finisher files were used after biomechanical preparation to remove debris and smear layer. All specimens were finally rinsed with 3 ml of 3% sodium hypochlorite. The teeth underwent longitudinal splitting and grooving in the coronal, middle, and apical thirds, and then, the samples were taken for scanning electron microscopy to evaluate the amount of smear layer removal in each third.</p><p><strong>Results: </strong>The middle and coronal thirds Showed that almost similar efficacy to remove smear layer in both Group II and Group III. At the apical third, Group III showed comparatively better results than Group I, II, and IV, respectively.</p><p><strong>Conclusion: </strong>Equal amount of smear layer was seen with EndoActivator and PATS Vario system when used as sonic irrigation devices.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"42 3","pages":"195-202"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142157107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of antimicrobial efficacy of various intracanal medicament in young permanent teeth: An in vivo study.","authors":"Anusha Dixit, Rishabh Kapoor, Divya Doneria, Shivani Mathur, Saakshi Goel, Rishba Singh","doi":"10.4103/jisppd.jisppd_214_24","DOIUrl":"10.4103/jisppd.jisppd_214_24","url":null,"abstract":"<p><strong>Introduction: </strong>Bacteria and their byproducts are key contributors to the onset and perpetuation of pulpoperiapical pathosis. Intracanal medication is vital in achieving successful endodontic outcomes as it targets and eradicates remaining microorganisms following biomechanical preparation.</p><p><strong>Aim and objective: </strong>The aim of the study was to compare and evaluate the antimicrobial efficacy of calcium hydroxide (CH) paste, triple antibiotic paste (TAP), and probiotics (PBs) as intracanal medicament in 12-17-year-old children undergoing root canal treatment for the management of infected pulpal tissues in young permanent teeth.</p><p><strong>Materials and methods: </strong>A total of 30 patients aged 12-17 years indicated for endodontic therapy in maxillary incisors and with no systemic complications were selected. They were randomly divided into three groups, i.e., Group I - CH group, Group II - TAP, and Group III - PB allocating 10 teeth in each group. After access opening, the first sample (S1) was collected by inserting a paper point into the root canal, the second sample (S2) was collected immediately after biomechanical preparation, and the third sample (S3) was collected after 7 days, i.e., postintracanal medication. Samples were sent for microbiological analysis to assess the microbial count, and statistical analysis was done for the obtained data.</p><p><strong>Results: </strong>The three intracanal medicaments were successful in reducing the microbial counts of Enterococcus faecalis in the infected root canals. However, according to the results of the study, the PB group demonstrated greater effectiveness against E. faecalis compared to the CH group and displayed similar antimicrobial efficacy as the TAP group.</p><p><strong>Conclusion: </strong>PB exhibited antimicrobial efficacy comparable to TAP but greater than Ca (OH) 2 paste. Hence, PB can be utilized as an intracanal medicament in young permanent teeth.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"42 3","pages":"203-210"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142157091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of oral complications in children undergoing chemotherapy: An observational study.","authors":"P Ambati, Virat Galhotra, Sunil Natha Jondhale, Tundup Dolker, Mugilan Ravi, Parth Rathod","doi":"10.4103/jisppd.jisppd_219_24","DOIUrl":"10.4103/jisppd.jisppd_219_24","url":null,"abstract":"<p><strong>Background: </strong>Chemotherapy, a cornerstone treatment for childhood cancers, can negatively impact oral health. This study aimed to evaluate the prevalence and evolution of oral complications in these patients.</p><p><strong>Materials and methods: </strong>A prospective observational study enrolled 44 children diagnosed with malignancy undergoing chemotherapy at a tertiary care institute in central India. Oral examinations were performed at baseline, with follow-ups at 3-6 and 9-12 months. Data collected included demographics, medical history, oral hygiene practices, and oral lesions. Blood counts and World Health Organization grading for mucositis were used. Descriptive statistics and appropriate statistical tests analyzed the data (P ≤ 0.05).</p><p><strong>Results: </strong>Acute lymphoblastic leukemia (ALL) was the most prevalent malignancy. Children reported various oral complaints such as ulcers, bleeding gums, and difficulty eating. Mucositis prevalence significantly decreased over follow-up visits (baseline: 56.8% and second follow-up: 13.3%). Gingival inflammation was present, though mean scores decreased over time. Oral hygiene scores varied without significant changes. Caries experience scores increased from baseline to follow-up.</p><p><strong>Conclusion: </strong>This study identified a high prevalence of ALL and diverse oral complications in children undergoing chemotherapy. While mucositis severity lessened over time, other issues such as caries persisted. These findings highlight the critical need for preventive oral care strategies to safeguard this vulnerable population's oral health.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"42 3","pages":"184-189"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142157109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of silver diamine fluoride application on the microtensile bond strength of three commonly used restorative materials in primary teeth: An ultrastructural study.","authors":"Ishita Banerjee, Ananjan Chatterjee, Gautam Kumar Kundu, Shabnam Zahir, Swapan Kumar Purkait, Shikhar Kumar","doi":"10.4103/jisppd.jisppd_22_24","DOIUrl":"10.4103/jisppd.jisppd_22_24","url":null,"abstract":"<p><strong>Introduction: </strong>Caries in primary teeth rapidly advances owing to its thin structure, thereby requiring restoration. However, restorations often fail due to various causes such as secondary caries and reduced microtensile bond strength (μTBS), which calls for the use of antimicrobial agents such as silver diamine fluoride (SDF).</p><p><strong>Aim: </strong>This study aims to measure and analyse the effect of SDF application on the μTBS of three regularly used restorative materials to dentin of primary teeth as well as compare the types of bond failure interfaces under SEM.</p><p><strong>Materials and methods: </strong>The study comprised 60 samples equally divided into six groups among three restorative materials, namely, glass ionomer cement (GIC, Groups I and II), resin-modified glass ionomer cement (RMGIC, Groups III and IV), and composite resin (Groups V and VI) with subdivisions of A and B, where A represented samples with SDF application and B represented samples without SDF application.</p><p><strong>Results and observations: </strong>It was observed that μTBS of RMGIC to sound and carious dentin irrespective of SDF application was found to be statistically significant (P < 0.05), and when GIC, RMGIC, and composite resins were compared to both sound and carious dentin irrespective of SDF application, it was statistically significant (P < 0.05). SEM analysis revealed predominantly cohesive failures among all the groups.</p><p><strong>Conclusion: </strong>Based on the results, it was concluded that SDF has no adverse effect on the μTBS of GIC, RMGIC, and composite resin to both carious and sound dentin of primary teeth.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"42 3","pages":"240-248"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142157105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of temperature on rehydration and fracture resistance of reattached tooth fragments after crown fracture: An in vitro study.","authors":"Mohammad Atif, Nitesh Tewari, Garima Jhunjhunwala, Hemlata Nehta, Morankar Rahul, Vijay Prakash Mathur, Kalpana Bansal","doi":"10.4103/jisppd.jisppd_176_24","DOIUrl":"10.4103/jisppd.jisppd_176_24","url":null,"abstract":"<p><strong>Background: </strong>Uncomplicated crown fractures of maxillary anterior teeth are common dental injuries, and the bonding of fractured fragments is recommended for management. Rehydration of fragments improves bonding and fracture resistance. Therefore, the aim of this study was to compare the fracture resistance of the reattached tooth fragment of the incisor crown after rehydration using either a steamer or a humidifier.</p><p><strong>Materials and methods: </strong>Bovine teeth were used as a model. Fractured fragments were divided into three groups: Group I (no rehydration), Group II (rehydration by humidifier), and Group III (rehydration by steamer). Fragments were reattached using a standard bonding protocol. Fracture resistance was tested using a universal testing machine. Statistical analysis was performed using analysis of variance and Chi-square tests.</p><p><strong>Results: </strong>The force required to fracture the reattached fragments was significantly higher in Group II (humidifier) compared to Group I (no rehydration) (P = 0.005). Group III (steamer) had a force value similar to Group I, indicating no significant improvement in fracture resistance with steamer rehydration. The temperature inside the steam-based chamber reached an average of 95.7°C with 95% humidity, whereas the conventional humidification chamber had an average temperature of 39.2°C and 84% humidity.</p><p><strong>Conclusion: </strong>Within the limitations of the present study, the rehydration protocol using a steam-based chamber was found to have a significantly lower force required to fracture the reattached fragments as compared to humidifier-based chamber. This was not significantly different from the fragments which were reattached without rehydration.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"42 3","pages":"249-254"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142157106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Oral health status and oral health-related quality of life among children with type 1 diabetes mellitus in the age group of 11-14 years in Delhi-NCR Region.","authors":"Shruti Kulkarni, Amit Khatri, Rishi Tyagi, Namita Kalra, Nishant Raizada, Deepak Khandelwal","doi":"10.4103/jisppd.jisppd_139_24","DOIUrl":"10.4103/jisppd.jisppd_139_24","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to assess the impact of oral health status (OHS) and sociodemographic indicators on oral health-related quality of life (OHRQoL) among children with type 1 diabetes mellitus (T1DM) aged 11-14 years and compare it with age-matched nondiabetic children.</p><p><strong>Materials and methods: </strong>This cross-sectional study included 80 children aged between 11 and 14 years with T1DM and 80 age-matched nondiabetic children. The OHRQoL was measured using a validated structured Hindi version of the child perception questionnaire (CPQ11-14) questionnaire. The clinical OHS was assessed using the decayed, missing, or filled teeth index, plaque index (PI), and gingival index (GI). Associations between OHRQoL and independent predictors were analyzed with the log-linear Poisson model regression method.</p><p><strong>Results: </strong>CPQ11-14 scores were significantly lower in nondiabetic children than diabetic children, indicating better OHRQoL among nondiabetic children than diabetic children (P ≤ 0.05). The GI score exhibited a significantly lower value in nondiabetic children than in diabetic children (P = 0.014). In contrast, the mean decayed, missing, and filled teeth score showed a significantly higher value in nondiabetic children than in diabetic children (P ≤ 0.001). There was no difference in the mean PI of diabetic and nondiabetic children (P = 0.096).</p><p><strong>Conclusion: </strong>The result of the present study highlighted the detrimental effect of T1DM on OHRQoL in children.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"42 3","pages":"176-183"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142157121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges faced by dentists during provision of oral health care in children and adolescents with special health-care needs: A scoping review.","authors":"Shivya Tuli, Mousumi Goswami, Aditya Saxena, Supriya Bhatara, Bhawna Saxena, Rimpi Gogoi","doi":"10.4103/jisppd.jisppd_132_24","DOIUrl":"10.4103/jisppd.jisppd_132_24","url":null,"abstract":"<p><strong>Introduction/background: </strong>Oral health care for children with special health-care needs (CSHCN) is often overlooked despite a substantial global population with disabilities or special needs. This scoping review delves into the challenges dentists face in delivering oral health care to CSHCN.</p><p><strong>Methodology: </strong>The scoping review was conducted as per the guidelines of PRISMA-ScR with a search strategy based on the population, intervention, comparison, and outcome (PICO) framework of the research question. The databases searched were PUBMED, Google Scholar, and EBSCOhost. Articles published within 20 years and in the English language were included in the study.</p><p><strong>Results: </strong>The review included 20 studies and highlighted several significant barriers encountered by dentists when providing oral health care for CSHCN. They included inadequate training among dentists in managing special needs patients, the time-intensive nature of oral procedures for this population, and the unpredictable behaviors exhibited by CSHCN during dental visits.</p><p><strong>Conclusion: </strong>The findings underscore the crucial need to address the challenges dentists face in delivering oral health care to CSHCN.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"42 3","pages":"167-175"},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142157090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}