{"title":"Impact of intracanal cryotherapy on postoperative pain and antimicrobial efficacy in primary teeth: A randomized clinical trial.","authors":"Itika Jain, Shivani Mathur, Sakshi Joshi, Diksha Bhat, Shikha Choubey, Urvashi Verma","doi":"10.4103/jisppd.jisppd_358_26","DOIUrl":"10.4103/jisppd.jisppd_358_26","url":null,"abstract":"<p><strong>Context: </strong>Postoperative pain and persistent microbial contamination remain significant challenges in pediatric endodontics following pulpectomy. Intracanal cryotherapy has emerged as a promising adjunct because of its anti-inflammatory, analgesic, and antimicrobial properties. However, its effectiveness requires further clinical evaluation.</p><p><strong>Aim: </strong>The aim of the study was to compare the effect of intracanal cryotherapy using cold saline (2°C-4°C) with room temperature saline (25°C-30°C) on postoperative pain and antimicrobial efficacy during the pulpectomy procedure in primary teeth.</p><p><strong>Settings and design: </strong>A randomized clinical trial was conducted involving 30 children (3-7 years) requiring pulpectomy in primary teeth.</p><p><strong>Materials and methods: </strong>Participants were randomly allocated into two groups: Group I (room temperature saline) and Group II (cryotherapy with cold saline). Postoperative pain was assessed using the Wong-Baker Faces Pain Rating Scale at 6, 24, 48, and 72 h posttreatment. Antimicrobial efficacy was evaluated by comparing colony-forming units (CFUs) before and after irrigation via microbiological analysis.</p><p><strong>Statistical analysis: </strong>Data were analyzed using SPSS v26.0. Paired t - tests/Wilcoxon for intragroup; independent t -test/Mann-Whitney for intergroup were applied.</p><p><strong>Results: </strong>Both groups showed significant intragroup pain reduction over 6, 24, 48, and 72 h ( P < 0.05), with cryotherapy exhibiting lower mean scores but no intergroup differences ( P > 0.05). Microbial counts decreased significantly within groups ( P = 0.001: Group I: 4.23-2.21 and Group II: 3.69-0.68), with cryotherapy superior postintervention ( P < 0.001). No baseline differences were existed.</p><p><strong>Conclusions: </strong>Intracanal cryotherapy with cold saline is an effective, simple, and cost-efficient method for reducing postoperative pain and enhancing antimicrobial efficacy in primary teeth pulpectomy.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"44 5","pages":"560-569"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative evaluation of mineral trioxide aggregate, diode and erbium, chromium-doped yttrium, scandium, gallium, and garnet laser-assisted mineral trioxide aggregate pulpotomy in primary molars - A randomized controlled trial.","authors":"Vishal Vishal, Gyanendra Kumar, Mridula Goswami, Farheen Sultan, Neha Chauhan","doi":"10.4103/jisppd.jisppd_317_26","DOIUrl":"10.4103/jisppd.jisppd_317_26","url":null,"abstract":"<p><strong>Objectives: </strong>The success of pulpotomy depends on the medicament or technique used to preserve the vitality of the remaining radicular pulp. With the advent of bioactive materials and laser technology, newer modalities have been introduced to improve treatment outcomes. This randomized controlled trial clinically and radiographically compared pulpotomy using mineral trioxide aggregate (MTA), diode and erbium, chromium-doped yttrium, scandium, gallium, and garnet (Er, Cr: YSGG) laser-assisted MTA in primary molars.</p><p><strong>Materials and methods: </strong>Thirty-six children aged 5-8 years were randomly allocated into three groups ( n = 12 each): Group I- MTA pulpotomy, Group II- diode laser-assisted MTA pulpotomy, and Group III- Er, Cr: YSGG laser-assisted MTA pulpotomy. Clinical parameters (pain, swelling, mobility, sinus tract, and tenderness on percussion) and radiographic parameters (inter-radicular radiolucency, integrity of lamina dura, and pathological root resorption) were assessed at baseline and at 3-, 6-, and 9-month follow-ups. Statistical analysis included the Shapiro-Wilk test, one-way analysis of variance (ANOVA), repeated-measures ANOVA, Kruskal-Wallis test, and Friedman test, with significance set at P < 0.05.</p><p><strong>Results: </strong>All three groups demonstrated high clinical and radiographic success throughout the 9-month follow-up period. No statistically significant intergroup differences were observed. At 9 months, clinical success was 75% for MTA, 100% for Er, Cr: YSGG laser, and 91.7% for diode laser, while radiographic success was 100%, 100%, and 91.7%, respectively. The numerical differences did not reach statistical significance.</p><p><strong>Conclusion: </strong>MTA, diode laser, and Er, Cr: YSGG laser pulpotomy produced comparable clinical and radiographic outcomes in primary molars. Laser-assisted pulpotomy represents an effective alternative to conventional medicament-based vital pulp therapy.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"44 5","pages":"570-578"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N K Suma, M N Shwetha, Rajeev J Mudakavi, B V Basavaraj, S Nikitha
{"title":"Comparative evaluation of the remineralization potential of chitosan-fluoride-doped mesoporous silica nanoparticles hydrogel and casein phosphopeptide-amorphous calcium phosphate fluoride paste on the enamel of primary teeth: An in vitro study.","authors":"N K Suma, M N Shwetha, Rajeev J Mudakavi, B V Basavaraj, S Nikitha","doi":"10.4103/jisppd.jisppd_343_26","DOIUrl":"https://doi.org/10.4103/jisppd.jisppd_343_26","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the remineralization potential of chitosan-fluoride-doped mesoporous silica nanoparticles (FMSN) hydrogel and casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) paste on artificially demineralized enamel of primary teeth.</p><p><strong>Materials and methods: </strong>Thirty extracted primary central incisors were randomly allocated into two groups ( n = 15). Group CH received Chitosan-FMSN hydrogel, and Group GC received CPP-ACPF paste. The remineralizing agents were applied twice daily for 3 months. Remineralization was assessed using DIAGNOdent ® , while elemental composition and surface morphology were evaluated using energy-dispersive X-ray spectroscopy and field emission scanning electron microscopy.</p><p><strong>Statistical analysis: </strong>Intergroup comparisons were performed using an independent Student's t -test, and intragroup comparisons were performed using a paired t -test. Statistical significance was set at P < 0.05.</p><p><strong>Results: </strong>The CPP-ACPF group showed a significant increase in calcium content from 55.47% to 67.96% ( P = 0.001), whereas the Chitosan-FMSN group showed a decrease from 53.59% to 42.37% ( P = 0.095). The Ca/P ratio increased from 1.25 to 2.62 in the CPP-ACPF group and decreased from 1.16 to 1.04 in the Chitosan-FMSN group, with a significant intergroup difference at three months ( P = 0.003). DIAGNOdent ® values decreased from 10.66 to 2.40 in the CPP-ACPF group and from 10.06 to 4.26 in the Chitosan-FMSN group. FE-SEM demonstrated greater surface mineral coverage in the CPP-ACPF group.</p><p><strong>Conclusions: </strong>Under the conditions of this in vitro study, CPP-ACPF demonstrated greater remineralization-associated changes than Chitosan-FMSN hydrogel in primary enamel.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"44 5","pages":"602-608"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative evaluation of postfabrication thickness of thermoformed 3 mm and 4 mm mouthguards on crowded and proclined malocclusion models: An in vitro study.","authors":"Ritesh Kalaskar, Nidhi Sharma, Ashita Kalaskar","doi":"10.4103/jisppd.jisppd_389_26","DOIUrl":"https://doi.org/10.4103/jisppd.jisppd_389_26","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate and compare the postfabrication thickness (PFT) of thermoformed mouthguards fabricated from 3 mm and 4 mm ethylene-vinyl acetate (EVA) sheets on crowded and proclined dental models.</p><p><strong>Materials and methods: </strong>An in-vitro study was conducted using 20 mouthguards fabricated on dental stone models with crowded and proclined maxillary anterior teeth. Pressure-molded mouthguards were made using 3 mm and 4 mm EVA sheets. PFT was measured at standardized labial, buccal, and sulcus regions using an Iwanson caliper. Statistical analysis was performed using ANOVA, Tukey's post hoc test, and unpaired t -test ( P < 0.05).</p><p><strong>Results: </strong>Significant thickness reduction was observed in both 3 mm and 4 mm mouthguards. In crowded dentition, 42%-61% thinning occurred at labial surfaces and 53%-71% at the sulcus, while proclined dentition showed 40%-60% and 51%-67% thinning, respectively. Maximum thinning occurred at canines, whereas molars showed the least reduction.</p><p><strong>Conclusion: </strong>Thermoforming causes substantial reduction in mouthguard thickness, particularly in anterior regions. Dental alignment influences final thickness, and clinicians should consider postfabrication thinning when selecting EVA sheet thickness to ensure adequate protection.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"44 5","pages":"618-625"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M K Nasreen, Paul Chalakkal, Harsh Ulhas Manerkar, Ramya Ramanathan, Mira Miranda, Saloni Prabhakar Pednekar
{"title":"The accuracy of large language models in assessing tooth detection and identification, dental caries, periapical status, and tooth development from mixed dentition radiographs.","authors":"M K Nasreen, Paul Chalakkal, Harsh Ulhas Manerkar, Ramya Ramanathan, Mira Miranda, Saloni Prabhakar Pednekar","doi":"10.4103/jisppd.jisppd_352_26","DOIUrl":"https://doi.org/10.4103/jisppd.jisppd_352_26","url":null,"abstract":"<p><strong>Background: </strong>Various studies have evaluated the accuracy of large language models (LLMs) in the detection of periapical radiolucencies from adult radiographs and orthopantomographs. However, none have evaluated their efficacy in evaluating parameters from mixed dentition radiographs.</p><p><strong>Aim: </strong>The aim of this study was to evaluate the accuracy of GPT-5 (GT), Gemini 3 Pro (GP), and Sonar (SR) in assessing tooth detection and identification, dental caries, periapical status, and stages of tooth development.</p><p><strong>Settings and design: </strong>A total of 93 mixed dentition radiographs from children aged 6-12 years were included. Two pediatric dentists evaluated anonymized radiographs and were blinded to the outputs generated by the LLM.</p><p><strong>Methodology: </strong>A standardized prompt-engineering framework was used to instruct the LLM. The outputs generated were recorded in a Microsoft Excel spreadsheet and compared with the reference standard established by the examiners.</p><p><strong>Statistical analysis used: </strong>Stata Statistical Software (Release 19), Cohen's kappa coefficient, Cochran's Q test, and McNemar's test were used for statistical analysis. Statistical significance was established at P < 0.05.</p><p><strong>Results: </strong>GP was found to have the highest accuracy in identifying teeth. GP showed the highest observed and expected agreements in identifying caries levels. GP was better at recognizing advanced carious lesions, while GT and SR were better at identifying sound teeth. None of the LLMs could identify periodontitis. GP showed the best overall performance in identifying tooth development.</p><p><strong>Conclusions: </strong>GP was found to have the highest accuracy for all parameters among the LLMs tested. However, all the LLMs were found to be inferior to expert human judgment.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"44 5","pages":"546-552"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge and awareness of sensory processing disorder and sensory-adapted dental care among pediatric dentists: A cross-sectional survey.","authors":"Natasha Gambhir, Priyanka Sachdeva, Subhashree Sahoo, Avantika Tuli, Divya Singh, M Sarika","doi":"10.4103/jisppd.jisppd_310_26","DOIUrl":"https://doi.org/10.4103/jisppd.jisppd_310_26","url":null,"abstract":"<p><strong>Aim: </strong>The study aimed to assess the knowledge and awareness of sensory processing disorder (SPD) and sensory-adapted dental care among pediatric dentists and to identify gaps in the recognition, assessment, and management of children with SPD.</p><p><strong>Materials and methods: </strong>A cross-sectional questionnaire-based survey was conducted among 145 practicing pediatric dentists. A self-administered 14-item questionnaire was developed following a review of the literature to assess knowledge of SPD, awareness of diagnostic approaches, sensory-adapted dental environments (SADEs), and perspectives on caregiver involvement in the dental management of children with SPD. The questionnaire demonstrated acceptable internal consistency (Cronbach's α = 0.622), and principal component analysis identified four components explaining 91.95% of the total variance. Data were analyzed using descriptive statistics and Chi-square tests, with statistical significance set at P < 0.05.</p><p><strong>Results: </strong>Pediatric dentists demonstrated moderate knowledge of the clinical manifestations of SPD. However, awareness of standardized diagnostic tools and SADEs remained limited. Most participants recognized the importance of caregiver involvement and environmental modifications in improving the dental management of children with SPD, highlighting important gaps in diagnostic awareness and sensory-informed clinical care.</p><p><strong>Conclusion: </strong>Pediatric dentists demonstrated reasonable knowledge of the clinical manifestations of SPD; however, important gaps remain in awareness of diagnostic assessment methods and sensory-adapted dental care strategies. These findings highlight the need to strengthen undergraduate and postgraduate training and continuing dental education to promote evidence-based, sensory-informed pediatric dental care.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"44 5","pages":"540-545"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kavitha Swaminathan, Sunil Babu Kotha, M Sudhindra Baliga, T Subbalekshmi, Selvakumar Haridoss, Apathsakayan Renugalakshmi
{"title":"Burnout among pediatric dentists: A systematic review and meta-analysis.","authors":"Kavitha Swaminathan, Sunil Babu Kotha, M Sudhindra Baliga, T Subbalekshmi, Selvakumar Haridoss, Apathsakayan Renugalakshmi","doi":"10.4103/jisppd.jisppd_348_26","DOIUrl":"10.4103/jisppd.jisppd_348_26","url":null,"abstract":"<p><strong>Abstract: </strong>Burnout, encompassing high emotional exhaustion (EE), high depersonalisation (DP), and low personal accomplishment (PA) as measured by the Maslach Burnout Inventory (MBI), remains poorly characterised among paediatric dentists. This systematic review and meta-analysis aimed to estimate prevalence of MBI-based burnout dimensions and associated factors, following a protocol prospectively registered with PROSPERO (CRD420251238894) and reported per PRISMA 2020 and MOOSE guidelines. Five databases (PubMed/MEDLINE, Scopus, Web of Science, EBSCOhost, and Cochrane Library) were searched from inception to November 30, 2025, supplemented by Google Scholar, institutional repositories, and author contacts, for quantitative observational surveys using the MBI in paediatric dentists, residents, or faculty. Two reviewers independently extracted study characteristics, MBI domain scores, composite burnout definitions, and associated factors, with discrepancies resolved by consensus; methodological quality was assessed using the Joanna Briggs Institute Critical Appraisal Checklist for Prevalence Studies (2020, nine items), and evidence certainty was graded using GRADE. Five cross-sectional surveys (n=915; Jordan, Egypt, Lebanon, United States, and Republic of Korea) met inclusion criteria. Random-effects meta-analysis (Freeman-Tukey transformation) showed pooled prevalence estimates of 45% for high EE (95% CI: 27%-64%), 36% for high DP (10%-67%), and 27% for low PA (10%-49%); two studies using equivalent two-domain criteria yielded a composite burnout prevalence of 16% (4%-34%). Heterogeneity was extreme (I² > 90%) across all outcomes, with very low certainty of evidence. Burnout, particularly EE, is frequently reported among paediatric dentists, though estimates are highly context-dependent, and harmonised, longitudinal, multi-country studies with concurrent mental health measures are needed.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"44 5","pages":"491-498"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oral health status and treatment needs of children and adolescents with special healthcare needs in Raipur district of Central India: A cross-sectional study.","authors":"Krupali Gadhvi, Virat Galhotra, Rhea Gandham, Abhiruchi Galhotra, Atul Jindal, Tundup Dolker, Mugilan Ravi, Joseph Lepcha, Maneesha Babu","doi":"10.4103/jisppd.jisppd_407_26","DOIUrl":"https://doi.org/10.4103/jisppd.jisppd_407_26","url":null,"abstract":"<p><strong>Background: </strong>Children with special healthcare needs (CSHCN) often face elevated risks for oral diseases and significant challenges in accessing timely dental care. This study was conducted because data on the oral health status of CSHCN in Raipur, Chhattisgarh, India, were unavailable.</p><p><strong>Aim: </strong>The aim of the study was to determine the oral health status and treatment needs of individuals with special healthcare needs aged 3-19 years attending special institutes in Raipur district, Chhattisgarh, India.</p><p><strong>Design: </strong>A descriptive, institution-based cross-sectional study was conducted encompassing 684 CSHCN. Dental caries and oral hygiene status were recorded using the decayed, missing, and filled (DMFT)/dmft and OHI-S indices as per the World Health Organization Basic Methods criteria, employing a complete enumeration sampling technique. All examinations were performed on-site at the institutions, with findings for every participant captured on a purpose-built mobile application.</p><p><strong>Results: </strong>Dental caries prevalence was 67.7%, with an overall mean DMFT/dmft of 2.55. Mean DMFT/dmft did not differ significantly with age or sex but differed significantly across disability type; it did not differ significantly across socioeconomic status (SES). Fair oral hygiene was seen in 51.5% and poor oral hygiene in 12.0%; poorer hygiene was significantly associated with older age, disability type, and lower SES. Overall, 93.4% of participants required dental treatment. Developmental enamel defects were present in 41.4%, traumatic dental injuries affected 10.2%, and 24.9% exhibited a deleterious oral habit.</p><p><strong>Conclusion: </strong>A substantial and multifactorial unmet oral health need persists among CSHCN in Raipur; the findings indicate barriers to accessing dental care and caregiver awareness in relation to unmet oral health needs. Targeted interventions and policy reforms are vital for improving their oral health status.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"44 5","pages":"506-515"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative evaluation of clinical and radiographic outcomes of three different scaffolds in regenerative endodontic treatment - A randomized clinical trial.","authors":"Mousumi Goswami, Aditya Saxena, Prachi Pathak, Aayushi Sangal","doi":"10.4103/jisppd.jisppd_345_26","DOIUrl":"10.4103/jisppd.jisppd_345_26","url":null,"abstract":"<p><strong>Background: </strong>Regenerative endodontic procedures (REPs) have emerged as a biologically based treatment modality for immature nonvital permanent teeth, promoting continued root maturation and periapical healing. Platelet-rich fibrin (PRF), concentrated growth factor (CGF), and collagen hydroxyapatite-based scaffolds such as SynOss Putty have been used as scaffolds during regenerative therapy; however, comparative evidence regarding their effectiveness remains limited.</p><p><strong>Aim: </strong>To evaluate and compare the clinical and radiographic outcomes of PRF, CGF, and SynOss Putty as scaffolds in regenerative endodontic treatment of immature nonvital permanent teeth.</p><p><strong>Materials and methods: </strong>Fifteen immature nonvital permanent teeth in children aged 7-17 years were randomly allocated into three groups ( n = 5 each): PRF, CGF, and SynOss Putty. REPs were performed according to the American Association of Endodontists guidelines. Clinical and radiographic evaluations were carried out at 1, 3, 6, and 12 months. Outcome measures included pain, swelling, tenderness to percussion, mobility, periapical healing, root elongation, dentinal wall thickening, and root apex approximation.</p><p><strong>Statistical analysis: </strong>Data were analyzed using IBM SPSS Statistics software. Descriptive statistics and Chi-square/Fisher's exact tests were applied, with P < 0.05 considered statistically significant.</p><p><strong>Results: </strong>All groups demonstrated resolution of signs and symptoms during the follow-up period. At 12 months, the PRF group showed significantly greater reduction in periapical pathology and superior root elongation compared with CGF and SynOss Putty ( P = 0.048). PRF also demonstrated greater dentinal wall thickening and root apex approximation. CGF exhibited moderate regenerative potential, whereas SynOss Putty showed comparatively variable radiographic outcomes.</p><p><strong>Conclusion: </strong>All three scaffolds were clinically successful; however, PRF demonstrated superior radiographic healing and root development.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"44 5","pages":"579-589"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of dental caries experience and salivary electrolyte parameters among children aged 6-14 years with type 1 diabetes mellitus and healthy controls: An in vivo study.","authors":"Pritesh Gawali, Rahul Hegde, Anand Shigli, Ahilya Chougule","doi":"10.4103/jisppd.jisppd_387_26","DOIUrl":"https://doi.org/10.4103/jisppd.jisppd_387_26","url":null,"abstract":"<p><strong>Background: </strong>Type 1 diabetes mellitus (T1DM) is a chronic autoimmune disorder commonly affecting children and adolescents. Alterations in salivary composition and flow associated with diabetes may influence oral health, particularly dental caries. However, the relationship between dental caries and T1DM remains controversial.</p><p><strong>Aim: </strong>The aim of the study was to assess and compare dental caries experience and salivary electrolyte levels (sodium, potassium, and chloride) among children aged 6-14 years with T1DM and healthy controls.</p><p><strong>Materials and methods: </strong>This in vivo cross-sectional comparative study included 70 children (35 with T1DM and 35 healthy controls). Dental caries was recorded using dmft/dmfs and DMFT/DMFS indices. Unstimulated whole saliva was collected and analyzed for sodium (Na + ), potassium (K + ), and chloride (Cl - ) using an electrolyte analyzer. Data were statistically analyzed using Chi-square and unpaired t -tests.</p><p><strong>Results: </strong>Children with T1DM showed a lower mean dmft score (2.83 ± 2.23) compared to healthy controls (4.27 ± 3.41), though the difference was not statistically significant ( P = 0.059). Salivary sodium and chloride levels were significantly higher in the diabetic group ( P < 0.01), while potassium levels showed no significant difference between groups.</p><p><strong>Conclusion: </strong>Children with T1DM demonstrated altered salivary electrolyte composition with no significant difference in caries experience compared to healthy children. Dietary habits and metabolic control may play a protective role against dental caries in diabetic children. Early and regular oral health assessment should be an integral component of pediatric diabetes care.</p>","PeriodicalId":101311,"journal":{"name":"Journal of the Indian Society of Pedodontics and Preventive Dentistry","volume":"44 5","pages":"499-505"},"PeriodicalIF":0.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149027361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}