Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology最新文献

{"title":"Professor Dr. med. Georg Henneberg — 80 Jahre —","authors":"G. Pulverer","doi":"10.1016/S0176-6724(88)80134-2","DOIUrl":"10.1016/S0176-6724(88)80134-2","url":null,"abstract":"","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"270 1","pages":"Pages 1-2"},"PeriodicalIF":0.0,"publicationDate":"1988-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80134-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"111006849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rarely occurring Shigella serovars","authors":"Eva Aldová ,&nbsp;Jaroslava Sobotkova ,&nbsp;Olřich Hausner ,&nbsp;Karla Lázničková ,&nbsp;Svatava Hausnerová ,&nbsp;Olřich Novák ,&nbsp;Věra Paučková ,&nbsp;Michal Tarabčák","doi":"10.1016/S0176-6724(88)80104-4","DOIUrl":"10.1016/S0176-6724(88)80104-4","url":null,"abstract":"<div><p>In addition to the predominant <em>Shigella sonnei</em>, also rarely occurring <em>Shigella</em> serovars have been found in Czechoslovakia: 4 serovars of subgroup A (<em>S. dysenteriae</em> 3, 4, 7 and 12) and 11 serovars of subgroup C (<em>S. boydii</em> 2, 3, 5, 7, 9 lactose-positive, 10, 13,14 aerogenic, mannitol-negative, 15, 16 and the provisional serovar E 16553). First isolations of these serovars were mostly connected with cases imported from abroad. Some serovars were isolated repeatedly.</p><p>Newly recognized serovars of <em>S. flexneri</em> (3b, 5a) as well as biochemically aberrant strains of subgroup B (<em>S. flexneri</em>), C (<em>S. boydii</em>) and D (<em>S. sonnei</em>) were isolated. Frequency and importance of some <em>S. flexneri</em> serovars have been changing in the course of time, e.g. <em>S. flexneri</em> 2b, that had evidently been frequent in central Europe 40 years ago, disappeared completely.</p></div><div><p>Zusätzlich zu der vorherrschenden <em>Shigella</em> sonnei wurden auch selten vorkommende Shigella-Serovare in der Tschechoslowakei gefunden: 4 Serovare der Untergruppe A (S. dysenteriae 3, 4, 7 und 12) und 11 Serovare der Untergruppe C (S. boydii 2, 3, 5, 7, 9 Laktose-positiv, 10, 13, 14 aerogen, Mannit-negativ, 15, 16 und das vorläufige Serovar E 16553). Die Erstisolierungen dieser Serovare standen meist mit aus dem Ausland eingeschleppten Fällen in Zusammenhang. Einige Serovare wurden wiederholt isoliert.</p><p>Es wurden neu anerkannte Serovare von <em>S. flexneri</em> (3b, 5a) sowie biochemisch abweichende Stämme der Untergrupppen B (<em>S. flexneri</em>), C (<em>S. boydii</em>) und D (<em>S. sonnei</em>) isoliert. Häufigkeit und Bedeutung einiger Serovare von <em>S. flexneri</em> haben sich im Laufe der Zeit verändert, z. B. bei <em>S. flexneri</em> 2b, das offenbar vor 40 Jahren häufig in Europa vorkam und völlig verschwunden ist.</p></div>","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"269 2","pages":"Pages 257-265"},"PeriodicalIF":0.0,"publicationDate":"1988-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80104-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14324622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electron microscopic localization of lipoteichoic acid on group a streptococci","authors":"Miloš Rýc ,&nbsp;Barbara Wagner ,&nbsp;Manfred Wagner ,&nbsp;Ruth Bicová","doi":"10.1016/S0176-6724(88)80093-2","DOIUrl":"10.1016/S0176-6724(88)80093-2","url":null,"abstract":"<div><p>The location of lipoteichoic acid (LTA) on the surface of group A streptococci was studied by immunoelectron microscopic and ultrastructural cytochemical methods, i. e. by means of LTA antibodies labelled with ferritin, or concanavalin A labelled with ferritin or colloidal gold. All these methods proved the LTA to be located on the outer cell surface of most group A streptococcus strains. The differences in the intensity of labelling paralelled the hydrophobicity of the strains, being substantially higher in the strains exhibiting a high degree of hydrophobicity. Treatment of streptococci with pronase or trypsin led to a complete loss of surface-located LTA. On the other hand, pepsin treatment of streptococci under mild conditions resulted in an increased amount of surface-located LTA in some strains. On the isolated cell walls, LTA could be demonstrated only on the outer surface of the walls. These findings correlated well with the presumed role of group A streptococcus LTA in the adherence of streptococci to the epithelial cells which is accomplished with the aid of surface-located LTA molecules.</p></div>","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"269 2","pages":"Pages 168-178"},"PeriodicalIF":0.0,"publicationDate":"1988-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80093-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14190648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunomodulatory effects of staphylococcal lipoteichoic acid in early Listeria monocytogenes infection in Balb/c-mice","authors":"Y. Ohshima,&nbsp;J. Beuth,&nbsp;H.L. Ko,&nbsp;K. Roszkowski,&nbsp;D. Hauck,&nbsp;G. Pulverer","doi":"10.1016/S0176-6724(88)80103-2","DOIUrl":"10.1016/S0176-6724(88)80103-2","url":null,"abstract":"<div><p>Balb/c-mice were intravenously infected with 5 × 10⁴ viable cells of <em>Listeria monocytogenes</em> SLCC 4013. Liver, lung and spleen of the animals showed heavy organ colonization 48 h after infection. Pretreatment of experimental animals with staphylococcal lipoteichoic acid (LTA; 2 mg i.p. 7 and 3 days before challenge) significantly reduced the bacterial count in these organs. In vitro, peritoneal macrophages from LTA-treated mice significantly reduced listerial viability as compared to control cells (p &lt; 0.0025). In vitro, exposure of macrophages from non-treated animals to LTA did not influence their bacterial killing ability.</p></div><div><p>Balb/c-Mäuse wurden mit 5 × 10⁴ Keimen von <em>Listeria monocytogenes</em> Stamm SLCC 4013 intravenös infiziert, wodurch nach 48 Stunden eine massive Kolonisation von Lunge, Leber und Milz bewirkt wurde. Eine Vorbehandlung der Tiere mit Staphylokokken-Lipoteichonsäure (LTA; 2 mg i.p. 7 und 3 Tage vor Listerieninokulation) reduzierte die Keimzahl in diesen Organen signifikant. Peritonealmakrophagen von LTA vorbehandelten Balb/c-Mäusen zeigten in vitro eine signifikante Steigerung des Listerien-Abtötungseffektes, verglichen mit Phagozyten unbehandelter Tiere (p &lt; 0.0025). In vitro-Präinkubation von Makrophagen unbehandelter Mäuse mit LTA hatte keinen Einfluß auf deren Listerien-Abtötungseffekt.</p></div>","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"269 2","pages":"Pages 251-256"},"PeriodicalIF":0.0,"publicationDate":"1988-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80103-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14274336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and characterization of a specific receptor for human albumin on a group L streptococcus","authors":"Christoph Lämmler","doi":"10.1016/S0176-6724(88)80101-9","DOIUrl":"10.1016/S0176-6724(88)80101-9","url":null,"abstract":"<div><p>Certain group L streptococci demonstrate surface receptors for human albumin. Binding of ¹²⁵I-albumin to group L streptococci could be inhibited by unlabelled albumin preparations from humans, dogs, mice and bovines, but not by albumin from rabbits. The albumin-binding proteins (ABP) could be solubilized from the streptococcal surface by hot acid treatment of the bacteria and isolated by affinity chromatography on human-albumin sepharose. ABP and specific antisera produced against ABP inhibited 125I-albumin binding to group L streptococci. The molecular weight of ABP determined by SDS-PAGE and Western blotting, was approximately 48000 Dalton. ABP preparations of group G streptococci isolated from bovines and humans demonstrated cross reactivity with antiserum produced against group L streptococcal ABP.</p></div><div><p>Bestimmte Streptokokken der Gruppe L weisen Oberflächen-Rezeptoren für menschliches Albumin auf. Die Bindung von ¹²⁵I-Albumin an Streptokokken der Gruppe L konnte durch nicht markierte Albuminpräparate vom Menschen, Hund, Maus und Rind, aber nicht durch Kaninchen-Albumin gehemmt werden. Die Albumin-bindenden Proteine (ABP) konnten durch Hitze- und Säurebehandlung der Bakterien von der Streptokokkenoberfläche in Lösung gebracht und mittels Affinitäts-Chromatographie an Humanalbumin-Sepharose isoliert werden. ABP und spezifisches Antiserum gegen ABP hemmten die Bindung von ¹²⁵I-Albumin an Streptokokken der Gruppe L. Das mittels SDS-PAGE und Western blotting bestimmte Molekulargewicht von ABP betrug ca. 48000 Dalton. ABP-Zubereitungen aus vom Rind und vom Menschen isolierten Streptokokken der Gruppe G zeigten Kreuzreagibilität mit Antiserum gegen Streptokokken-ABP der Gruppe L.</p></div>","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"269 2","pages":"Pages 237-244"},"PeriodicalIF":0.0,"publicationDate":"1988-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80101-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13985739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occurrence and clinical importance of the pathogenic serogroup O:5, 27 of yersinia enterocolitica in the Federal Republic of Germany and methods for its serological and bacteriological identification","authors":"S. Aleksić ,&nbsp;J. Bockemühl ,&nbsp;H.H. Wuthe ,&nbsp;V. Aleksić","doi":"10.1016/S0176-6724(88)80096-8","DOIUrl":"10.1016/S0176-6724(88)80096-8","url":null,"abstract":"<div><p>Despite its world-wide distribution, the pathogenic serogroup O:5, 27 of <em>Yersinia enterocolitica (Y. e.)</em> has scarcely been considered in the Federal Republic of Germany. In the 1980 to 1986 period, a total of 74 strains from patients was identified at the National Reference Centre for Salmonella, Hamburg. The clinical manifestations of the cases was not different from those associated with <em>Y. e.</em> O:3 and O:9 infections. Six out of 8 patients from whom serum samples were available, developed moderate agglutination titres (1:80-1:1280). Only 8 of the 74 strains were negative in <em>in vitro</em> virulence tests.</p><p>A list of biochemical tests is given which permit a differentiation of the pathogenic serogroup O:5, 27 from the apathogenic <em>Y. e.</em> O:5 which is widely distributed in the environment. Serological studies revealed different H antigens in both serogroups. The O antigen factor 27, and a subfactor O:5₂ which is typical of <em>Y. e.</em> serogroup O:5, are further differential markers; the production of both factor sera is described.</p><p>Besides serogroups O:3 and O:9, <em>Y. e.</em> O:5, 27 must be considered as an aetiological agent of human yersiniosis in the Federal Republic of Germany.</p></div>","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"269 2","pages":"Pages 197-204"},"PeriodicalIF":0.0,"publicationDate":"1988-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80096-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14322969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Susceptibility of ureaplasma urealyticum to ten chemotherapeutic agents","authors":"Raimund Sobetzko ,&nbsp;Albert A. Hartmann,&nbsp;Peter Elsner","doi":"10.1016/S0176-6724(88)80102-0","DOIUrl":"10.1016/S0176-6724(88)80102-0","url":null,"abstract":"<div><p>Tetracyclines and erythromycin are the chemotherapeutic agents most often used in the Federal Republic of Germany for eradication of <em>U. urealyticum</em> from the male urogenital tract. Few data on current susceptibility in the FRG are available. Therefore, we investigated the minimal inhibitory concentration (MIC) values of 10 chemotherapeutic agents against 27 isolates from the male urethra and 4 ATCC strains of <em>U. urealyticum</em> by a micro broth dilution method using a modified U-9 medium. The MIC₉₀ values (μg/ml) of the chemotherapeutic agents tested were as follows: minocycline-0.25, doxycycline-1.0, tetracycline and chlortetracycline-2.0, erythromycin and streptomycin-4.0, chloramphenicol, gentamicin, rosoxacin-8.0, spectinomycin-32.0. According to the blood levels attained in treatment, the chemotherapeutic agents can be divided into three groups based on the MIC₉₀-values, i.e. sensitive: chloramphenicol, doxycycline, minocycline and streptomycin; weakly effective: Chlortetracycline, tetracycline, spectinomycin and erythromycin; and resistant: gentamicin and rosoxacin.</p></div><div><p>Tetrazykline und Erythromycin sind die in der Bundesrepublik Deutschland am häufigsten eingesetzten Chemotherapeutika gegen <em>U. urealyticum</em> im männlichen Urogenitaltrakt. Daten zur aktuellen Resistenz-Situation von <em>U. urealyticum</em> gegen Chemotherapeutika stehen kaum zur Verfügung. Deshalb untersuchten wir 27 klinische Isolate und 4 Stämme (ATCC) mittels Mikro-Reihenverdünnungstest gegen 10 Chemotherapeutika, die auch bei sexuell übertragbaren Krankheiten (STD) eingesetzt werden. Die minimale Hemmkonzentration 90 (MHK90) (μg/ml) betrug für: Minocyclin 0,25; Doxycyclin 1,0; Tetracyclin und Chlortetracyclin 2,0; Erythromycin und Streptomycin 4,0; Chloramphenicol, Gentamicin, Rosoxazin 8,0; Spectinomycin 32,0. Aufgrund der therapeutisch erreichbaren Serumspiegel und der ermittelten MHK₉₀-Werte können die getesteten Chemotherapeutica in die Gruppen: sensibel: Chloramphenicol, Doxycyclin, Minocyclin und Streptomycin, schwach empfindlich: Chlortetrazyklin, Tetrazyklin, Spectinomycin und Erythromycin und resistent: Gentamicin und Rosoxazin eingeteilt werden.</p></div>","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"269 2","pages":"Pages 245-250"},"PeriodicalIF":0.0,"publicationDate":"1988-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80102-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14109602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitivity to colicin Js, one of important characteristics of Escherichia coli strains belonging to enteroinvasive serovars","authors":"V. Horák ,&nbsp;J. Sobotková","doi":"10.1016/S0176-6724(88)80091-9","DOIUrl":"10.1016/S0176-6724(88)80091-9","url":null,"abstract":"<div><p>Of the 96 <em>E. coli</em> strains belonging to 9 enteroinvasive serovars 79 (82.3%) turned out to be sensitive to colicin J_s but none of the 115 strains of <em>E. coli</em> isolates from the feces of healthy persons without diarrhoea exhibited this type of sensitivity reaction. Of the colicin J_s-sensitive strains, 89.9% (71 out of 79) gave also positive reactions in the Serény test for enteroinvasiveness. The remaining strains belonging to enterointervasive <em>E. coli</em> serovars but showing no sensitivity to colicin J_s were as a rule negative in the Serény test.</p></div>","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"269 2","pages":"Pages 156-159"},"PeriodicalIF":0.0,"publicationDate":"1988-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80091-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14190647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deoxyribonucleic acid relatedness amongst staphylococcus epidermidis and staphylococcus saprophyticus strains","authors":"J. Zakrzewska-Czerwinska ,&nbsp;M. Mordarski ,&nbsp;M. Goodfellow ,&nbsp;G. Pulverer","doi":"10.1016/S0176-6724(88)80094-4","DOIUrl":"10.1016/S0176-6724(88)80094-4","url":null,"abstract":"<div><p>The degree of binding was determined between DNA preparations from 65 staphylococci representing clusters defined in a numerical phenetic survey and ³H-labelled DNA from reference strains of <em>S. epidermidis, S. haemolyticus, S. hominis, S. saprophyticus</em> and <em>S. warneri</em>. The congruence between the DNA pairing and numerical phenetic data was good with <em>S. epidermidis</em> and <em>S. saprophyticus</em> being shown to be genomic species. However, some strains identified as <em>S. epidermidis</em> using recommended diagnostic procedures were found to belong to other taxa, notably <em>S. simulans</em> and <em>S. warneri</em>. The moles percent guanine plus cytosine content of the DNA of the test strains was within the range 27 to 34.</p></div><div><p>DNA-Hybridisierungstests an insgesamt 65 Stämmen von koagulasenegativen Staphylokokken wurden mit ³H-markierter Referenz-DNA von Typstämmen der Spezies <em>Staphylococcus epidermidis, S. haemolyticus, S. hominis, S. saprophyticus</em> und <em>S. warneri</em> durchgeführt. Zwischen den Daten der numerischen Taxonomie und den jetzigen DNA-Hybridisierungstests konnte bei den Stämmen der Spezies <em>S. epidermidis</em> und <em>S. saprophyticus</em> eine gute Übereinstimmung konstatiert werden. Einige Stämme waren allerdings falsch klassifiziert worden, sie gehören zu anderen Spezies wie <em>S. simulans</em> und <em>S. warneri</em>. Die Guanin-und Cytosin-Werte der überprüften Staphylokokken lagen zwischen 27 und 34 mol%.</p></div>","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"269 2","pages":"Pages 179-187"},"PeriodicalIF":0.0,"publicationDate":"1988-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80094-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14322968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rickettsiae of the spotted fever group associated with the host-parasite system Oryctolagus cuniculi/Rhipicephalus pusillus","authors":"L. Ciceroni ,&nbsp;A. Pinto ,&nbsp;C. Rossi ,&nbsp;C. Khoury ,&nbsp;L. Rivosecchi ,&nbsp;E. Stella ,&nbsp;B. Cacciapuoti","doi":"10.1016/S0176-6724(88)80099-3","DOIUrl":"10.1016/S0176-6724(88)80099-3","url":null,"abstract":"<div><p>Wild rabbits — <em>Oryctolagus cuniculi</em> — living in large numbers in a protected zone of Tuscany, the park of Migliarino — San Rossore — Massaciuccoli, showed to be carriers of the hard tick <em>Rhipicephalus pusillus</em>, previously observed in North Africa and Sicily.</p><p>Antibodies to <em>Rickettsia conorii</em> and <em>R. slovaca</em> were detected in 78.9 per cent of the wild rabbits captured in that area. Seroconversion towards <em>R. conorii</em> was also observed in guinea pigs inoculated with homogenates of <em>R. pusillus</em> parasitizing the wild rabbits. These results identify an ecological niche of rickettsiae of the Spotted fever group in the host-parasite system <em>O. cuniculi/R. pusillus</em>.</p><p>Attempts to isolate rickettsiae from the ticks and the wild rabbits were unsuccessful both in the egg yolk sac and in the guinea pig. This failure probably shows the low pathogenicity of the ricketsiae parasitizing the biosystem <em>O. cuniculi/R. pusillus</em>.</p></div><div><p>Wildkaninchen (<em>Oryctolagus cuniculi</em>), die in großer Zahl in einem Schutzgebiet in der Toscana, dem Park von Migliarino — San Rossore — Massaciuccoli, leben, erwiesen sich als Träger der Lederzecke <em>Rhipicephalus pusillus</em>, die früher in Nordafrika und Sizilien beobachtet wurde. Bei 78,9% der in diesem Gebiet gefangenen Wildkaninchen wurden Antikörper gegen <em>Rickettsia conorii</em> und <em>R. slovaca</em> festgestellt. Eine <em>R. coworii</em>-Serokonversion wurde auch bei Meerschweinchen beobachtet, die mit Homogenaten des Wildkaninchen-Parasiten <em>R. pusillus</em> beimpft worden waren. Diese Ergebnisse lassen eine ökologische Nische für die Rickettsien der Spotted-Fever-Gruppe in dem Wirt-Parasiten-System <em>O. cuniculo — R. pusillus</em> erkennen. Bemühungen um eine Isolierung der Rickettsien aus den Zecken und den Wildkaninchen im Eidottersack und die Meerschweinchen blieben erfolglos. Dieser Mißerfolg zeigt vermytlich die niedrige Pathogenität der im Biosystem <em>O. cuniculi — R. pusillus</em> parasitierenden Rickettsien.</p></div>","PeriodicalId":101291,"journal":{"name":"Zentralblatt für Bakteriologie, Mikrobiologie und Hygiene. Series A: Medical Microbiology, Infectious Diseases, Virology, Parasitology","volume":"269 2","pages":"Pages 211-217"},"PeriodicalIF":0.0,"publicationDate":"1988-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0176-6724(88)80099-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14322970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}