World Science and Technology最新文献

{"title":"Discussion of the Clinical Research for Integrating Traditional Chinese Medicine and Western Medicine in the Treatment of HIV/AIDS Herpes Zoster","authors":"Pan Juhua,&nbsp;Huang Shijing,&nbsp;Wu Wei,&nbsp;Xue Liuhua,&nbsp;Wang Jie","doi":"10.1016/S1876-3553(12)60010-6","DOIUrl":"https://doi.org/10.1016/S1876-3553(12)60010-6","url":null,"abstract":"<div><p>Herpes zoster in HIV/AIDS patients is characterized by high incidence, wide skin damage, intractability, long course, and high recurrence rate. It is an important opportunistic infection among HIV/AIDS patients. By summarizing clinical practice and the theories in ancient books and recent manuscripts, we argue that the key to pathogenesis is the exogenous pathogenic toxin and endoretention of damp heat, resulting in herpes in the skin. HIV/AIDS herpes zoster localizes in the liver and gallbladder, in addition to being closely related to the heart and the spleen, according to traditional Chinese medicine (TCM) theories. The syndrome types of HIV/AIDS herpes zoster include heat stagnation in the liver channel, spleen deficiency with dampness, <em>qi</em>-stagnation, and blood stasis. In this article, we discussed clinical research of HIV/AIDS herpes zoster in TCM with reference to its disease characteristics, etiology, pathogenesis, diagnosis, and syndrome differentiation, in addition to the treatment of HIV/AIDS herpes zoster patients.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"13 2","pages":"Pages 244-247"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(12)60010-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91683947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment of Acupuncture Module in the Four-Diagnoses Auxiliary Apparatus","authors":"Wang Jing,&nbsp;Yang Xuezhi,&nbsp;Zhu Qingwen,&nbsp;Li Haiyan,&nbsp;Guo Zhou,&nbsp;Niu Xin","doi":"10.1016/S1876-3553(12)60006-4","DOIUrl":"https://doi.org/10.1016/S1876-3553(12)60006-4","url":null,"abstract":"<div><p>The concept of four diagnoses in traditional Chinese medicine (TCM) is considered the main diagnostic principle in TCM practice. The development of TCM should be based on inheritance and innovation. In recent years, studies on TCM diagnostic equipments have promoted the digital and objective development of TCM in both clinical practice and scientific research. BD-SZ/TCM Four-Diagnoses Auxiliary Apparatus (BD-SZ/TCM-FDAA) detects the pulse and analyzes the tongue through various devices. The health condition of a patient is evaluated by the four-diagnostic analysis system according to TCM theories. The results of TCM diagnosis and the recommended prescriptions are provided to assist in clinical treatment. Developing and integrating an acupuncture module into the BD-SZ/TCM-FDAA is important for the further promotion of TCM both at home and abroad. The prescription of the recommended acupoint also highlights the portable feature of the BD-SZ/TCM-FDAA. The development of an acupuncture module serves an active role in TCM clinical practice, teaching, and self-learning by TCM doctors. This article discusses the structure of the acupuncture module and its integration and optimization with the existing four-diagnoses syndrome-differentiation system of TCM.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"13 2","pages":"Pages 266-270"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(12)60006-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90001130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gut Microbiota-targeted, Whole-Body Systems Biology for Understanding Traditional Chinese Medicine","authors":"Zhang Xu ,&nbsp;Zhao Yufeng ,&nbsp;Hu Yiyang ,&nbsp;Liu Ping ,&nbsp;Zhao Liping","doi":"10.1016/S1876-3553(12)60007-6","DOIUrl":"10.1016/S1876-3553(12)60007-6","url":null,"abstract":"<div><p>Traditional Chinese medicine (TCM) is a medical system with its own theoretical framework focusing on functions at the whole-body level, and it has accumulated abundant clinical experience. However, TCM approaches are empirical, and the manifestations that it reads in human bodies can hardly be communicated in molecular language with modern medicine. Whole-body systems biology considers the human body as a “superorganism,” which consists of cells of both human and symbiotic microorganisms. Taking advantage of “-omic” technologies, biological information in urine, fecal, and blood samples can be profiled as emergent functions of the complex human system for understanding its dynamics in disease and health. This top-down systems biology approach emphasizes the functions of gut microbiota in human health. It is a holistic approach similar to TCM, but it assesses human health with molecular-marker-based methods; therefore, it can serve as a bridge between TCM and western medical science. This article summarizes the concepts, methodologies, clinical applications, and advantages of “functional metagenomics,” a whole-body systems-biology platform, as a new research strategy for modernization of TCM.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"13 2","pages":"Pages 202-212"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(12)60007-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74208468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishment of Acupuncture Module in the Four-Diagnoses Auxiliary Apparatus","authors":"Wang Jing, Yang Xuezhi, Zhu Qingwen, L. Haiyan, Guo Zhou, Niu Xin","doi":"10.1016/S1876-3553(12)60006-4","DOIUrl":"https://doi.org/10.1016/S1876-3553(12)60006-4","url":null,"abstract":"","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"11 1","pages":"266-270"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78805240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Cluster Analysis of Acupuncture-Manipulation Parameters","authors":"Hu Yin'e,&nbsp;Yang Huayuan,&nbsp;Liu Tangyi","doi":"10.1016/S1876-3553(12)60002-7","DOIUrl":"10.1016/S1876-3553(12)60002-7","url":null,"abstract":"<div><p>Acupuncture manipulation is one of the key factors in the determination of the clinical therapeutic effect of acupuncture and moxibustion. The acquired simulated expert's acupuncture-manipulation methods and characteristics were processed using a cluster algorithm to show the parameters and rules of acupuncture manipulation. The theoretical basis is established based on the standardization, normalization, and quantification of acupuncture-manipulation parameters.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"13 1","pages":"Pages 59-63"},"PeriodicalIF":0.0,"publicationDate":"2011-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(12)60002-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74008279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Theories Based on Bodily Experience and Perception: Analysis of Metaphorical Characteristics of Etiology in Traditional Chinese Medicine Using Wind of the Six Evils as an Example","authors":"Jia Chunhua","doi":"10.1016/S1876-3553(12)60003-9","DOIUrl":"10.1016/S1876-3553(12)60003-9","url":null,"abstract":"<div><p>Methods used in the etiology of traditional Chinese medicine (TCM) are briefly reviewed. This article discusses the metaphorical characteristics of TCM in the analysis of etiology systematically. Wind, one of the six evils, is used as an example. It concludes that ancient TCM physicians transplanted some properties of the natural wind into the explanation of TCM theories. Consequently, the concept of wind as a pathogenic factor and the disease-related characteristics of wind have been used in the medical field. This is the method of metaphorical cognition from the perspective of cognitive linguistics, which interprets unfamiliar things with the help of familiar things. The term “six evils” in TCM is a metaphorical concept used in the explanation of TCM etiology.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"13 1","pages":"Pages 47-51"},"PeriodicalIF":0.0,"publicationDate":"2011-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(12)60003-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89185142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"System Medicine and Translational Medicine","authors":"Luo Guoan,&nbsp;Wang Yiming,&nbsp;Liang Qionglin,&nbsp;Xie Yuanyuan,&nbsp;Fan Xuemei","doi":"10.1016/S1876-3553(12)60001-5","DOIUrl":"10.1016/S1876-3553(12)60001-5","url":null,"abstract":"<div><p>In this perspective study, the authors introduce the background, goals, and roadmap of Translational Medicine, address the differences between oriental and western medicines, as well as their development tendency, and then discuss the developments in and prospects for the System Medicine. The advantages of Traditional Chinese Medicine (TCM) lie in its guidelines based on the holism and systems theory; its methodology based on the theory as “the harmony between humans and nature” to regulate the body's balance; and its personalized treatment with TCM formulas. However, modernization of TCM still faces some challenges: how to translate the self-explanatory closed system into an receptively open system; how to achieve the combination, integration, and convergence of TCM with other modern sciences and technologies (such as systems biology); how to implement the modern scientific mode, methodologies, and achievements in the study of TCM, and interpret it with data instead words. Although there is a large difference between the oriental and western medicine systems, the trend of complementary development and integration of both is irresistible. We should try to push the progress in the combination, integration, and convergence of oriental and western medicines to welcome the emergence of System Medicines in the 21st century. The development of System Medicine may have following requirements and characteristics: first, the integrated research on medicine and pharmacy requires the “system–system” interaction character between the drug system and biological system; second, the clinical diagnosis system by the combination of disease and syndrome requires an integrative expression, including some quantitative indexes of syndromes in TCM, some pathological and biochemical indexes as well as imaging diagnostic markers in western medicine, and some biomarkers, such as genes, proteins, and metabolites discovered by systems biology studies; third, a clinical-treatment mode based on the correspondence of formula, disease and syndrome requires that the pattern of compound drugs be widely used for the human system by the combination of disease and syndrome, in order to achieve goals known as “correspondence of formula, disease and syndrome, comprehensive management and systematic condition” fourth, the research and development (R&amp;D) mode of new drugs require “participation of physicians and combination of medicine and pharmacy”, which is a route known as “Beside-Bench-Beside” fifth, the representation of compound drugs and human system requires the combination of macroscopic characterization and microcosmic feature, also the combination of qualitative and quantitative analyses.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"13 1","pages":"Pages 1-8"},"PeriodicalIF":0.0,"publicationDate":"2011-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(12)60001-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89749959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodological Framework of Relativity Research on Efficacy and Drug Nature of Cold and Hot of Traditional Chinese Drugs","authors":"Wang Peng,&nbsp;Wang Zhenguo,&nbsp;Ouyang Bing","doi":"10.1016/S1876-3553(12)60005-2","DOIUrl":"10.1016/S1876-3553(12)60005-2","url":null,"abstract":"<div><p>This study aimed to analyze and study the efficacy and nature of cold and hot traditional Chinese drugs (TCDs). TCDs of both cold and hot natures have different interventional effects on the constitution and syndromes of cold and hot physical natures of the body. A syndrome-based method for relative research has been conducted on the efficacy of TCDs of both cold and hot natures. The key research conducted on syndrome models includes the study of the relationship between the efficacy and cold and hot nature of the TCDs, in addition to a relative research between the material components and efficacy of TCDs of cold and hot natures. Research was also conducted to determine the characteristic effects of cold and hot TCDs on normal models and on cold- and hot-constitution models. A comparative research of the mechanism of action of cold and hot TCDs was conducted based on the different models. The relative research on the efficacy of cold and hot TCDs also analyzed and summarized the model preparation, indicator observation, and control design.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"13 1","pages":"Pages 129-132"},"PeriodicalIF":0.0,"publicationDate":"2011-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(12)60005-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75014672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Four-Diagnoses Auxiliary Apparatus based on Chinese Medicine in Health Evaluation and Constitution Identification","authors":"Wang Jing,&nbsp;Yang Xuezhi,&nbsp;Zhu Qingwen,&nbsp;Dong Xiaoying,&nbsp;Li Haiyan,&nbsp;Guo Zhou,&nbsp;Niu Xin","doi":"10.1016/S1876-3553(12)60004-0","DOIUrl":"10.1016/S1876-3553(12)60004-0","url":null,"abstract":"<div><p>The understanding of health has deepened with social development, scientific improvement, and environmental changes. The focus has changed from disease-oriented to health-oriented viewpoint. Hence, it is important to evaluate health using objective and accurate criteria. The four-diagnosis methods and syndrome differentiation are focused on differences among individuals according to the <em>yin, yang, qi,</em> and blood conditions. These differences are closely related to the constitution of a subject. The promotion of constitution identification among healthy and subhealthy groups and patients is beneficial for subjects to understand their body characteristics. It is important in daily health cultivation and disease prevention. Digital and objective information of a subject is acquired by the traditional Chinese medicine (TCM) Four-Diagnosis Auxiliary Apparatus efficiently and accurately. The automatic extraction and recognition of all the information is an important step in the diagnosis and constitution identification process by TCM.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"13 1","pages":"Pages 70-73"},"PeriodicalIF":0.0,"publicationDate":"2011-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(12)60004-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90974573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discussion on the Investigation Idea of Quality Control of Chinese Materia Medica Based on Metabolomics Technology","authors":"Fan Gang,&nbsp;Zhou Lin,&nbsp;Lai Xianrong,&nbsp;Wang Zhang,&nbsp;Zhang Yi","doi":"10.1016/S1876-3553(11)60033-1","DOIUrl":"10.1016/S1876-3553(11)60033-1","url":null,"abstract":"<div><p>Metabolomics is a new omics technology which is developed after the genomics, transcriptomics, and proteomics. Metabolomics has characteristics of integrity, systematization, and comprehensiveness which just coincide with the whole view, dynamic concept, and dialectic approach of the traditional Chinese medicine theories. This study reviews the application of metabolomics in effective material bases and quality evaluation of Chinese Materia Medica (CMM). An integral research idea of quality control has also been put forward on the basis of metabolomics technology because of the deficiency of current quality control methods in CMM. That is, the technology and methods of metabolomics are used to ascertain the effective material bases of CMM and factors affecting the metabolic change of chemical constituents in medicinal plant. Then, a quality control method can be established to ensure the safety and effectiveness of CMM in clinical practice.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"12 6","pages":"Pages 870-875"},"PeriodicalIF":0.0,"publicationDate":"2010-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(11)60033-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89135336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}