World Science and Technology最新文献

{"title":"Study on Application of Medical Diagnosis by Electronic Nose","authors":"Zhezhou Zheng,&nbsp;Xuejuan Lin","doi":"10.1016/S1876-3553(13)60016-2","DOIUrl":"10.1016/S1876-3553(13)60016-2","url":null,"abstract":"<div><p>In recent years, with the in-depth research of electronic nose technology, the bionic olfactory system has been widely applied in the medical field. This article elaborated basic components, working principle, recent achievements of electronic nose in the modern medical application. And it proposed a new mode about combination of the electronic nose technology with the dialectical thinking of traditional Chinese medicine (TCM).</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"14 6","pages":"Pages 2115-2119"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(13)60016-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75953801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in Ginsenoside Rh2 and Its Derivatives","authors":"Man Cao ,&nbsp;Jie Zhang ,&nbsp;Yang Zhao ,&nbsp;Xinbo Song ,&nbsp;Baiping Ma","doi":"10.1016/S1876-3553(13)60018-6","DOIUrl":"10.1016/S1876-3553(13)60018-6","url":null,"abstract":"<div><p>Ginsenoside Rh₂, one of the characteristic components in red ginseng (roots steamed at 98-100 °C without peeling), is a rare ginsenoside with potential bioactivity. The preparation of ginsenoside Rh₂ was studied by using acid hydrolysis, alkaline hydrolysis, synthesis and biotransformation techniques. Microbial and enzymatic transformations were regarded as the optimization methods of all these techniques, owing to their high specificity, yield and productivity. The pharmacological activities and pharmacokinetics of ginsenoside Rh₂ and its derivatives were extensively researched. In this paper, their preparation and activities have been reviewed, which can provide information for the research and development of ginsenoside Rh₂.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"14 6","pages":"Pages 2205-2211"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(13)60018-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90095016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electronic Nose and Its Application in Chinese Materia Medica","authors":"Huiqin Zou,&nbsp;Yu Han,&nbsp;Shu Xing,&nbsp;Queyue Lin,&nbsp;Zedong Wei,&nbsp;Yin Xiong,&nbsp;Yonghong Yan","doi":"10.1016/S1876-3553(13)60017-4","DOIUrl":"10.1016/S1876-3553(13)60017-4","url":null,"abstract":"<div><p>Electronic nose (E-nose) is a rapid, simple, sensitive and accurate technology for the quality evaluation of Chinese materia medica (CMM). In this paper, several CMM samples of different species, habitats, storage time, and so on were analyzed by E-nose. Based on experimental data, specific discrimination model was established according to specific research target using different pattern recognition algorithms including PCA, DFA, PLS, BP-ANN and so on. It showed that the models were reliable and stable. It was concluded that E-nose can be applied to effectively extract and analyze the odor traits of CMM. It is a unique and useful tool for research on the identification, quality control and validity evaluation of CMM.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"14 6","pages":"Pages 2120-2125"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(13)60017-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78561704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CDISC Standards and Clinical Research Data Standardization of Traditional Chinese Medicine","authors":"Yanlan Li ,&nbsp;Jingqing Hu ,&nbsp;Baoyan Liu","doi":"10.1016/S1876-3553(13)60015-0","DOIUrl":"10.1016/S1876-3553(13)60015-0","url":null,"abstract":"<div><p>More and more attention has been paid to the standardization of clinical research data. International clinical data standards mainly include four categories, which are the File Format, Exchange Standard, Analysis Standard and Terminology Standard. Clinical Data Interchange Standards Consortium (CDISC) is the main criteria of exchanging standard and analyzing standard currently. Backwardness of quality and level of the data management have become one of the most important factors that affect the sustained, rapid and healthy development of domestic clinical trials. How to apply international standards of clinical data to narrow the gap of clinical research of Chinese medicine with the international advanced level is a topic which needs to be continuously explored. This paper firstly introduced the CDISC and its two standards, then analyzed the significance of data standardization in clinical research of traditional Chinese medicine (TCM), and finally discussed problems existed in the process of TCM clinical research using CDISC standards. It was suggested that the strengthening on research of relevant TCM semantic structure and its terminology standard is the key problem. The only way to solve this problem is to use the CDISC standards.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"14 6","pages":"Pages 2109-2114"},"PeriodicalIF":0.0,"publicationDate":"2012-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(13)60015-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90503384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experience of Professor Shen Shu-wen in the Treatment of Migraine","authors":"Zhihong Yang ,&nbsp;Shuwen Shen ,&nbsp;Yahuan Yuwen","doi":"10.1016/S1876-3553(13)60014-9","DOIUrl":"10.1016/S1876-3553(13)60014-9","url":null,"abstract":"<div><p>Professor <em>Shen Shu-wen</em> is the national traditional Chinese medicine (TCM) academic expert of the fourth and the fifth batch of the experience inheritance of famous and veteran doctors of TCM in China. He is specialized in the treatment of rare illness of internal medicine. He emphasizes on the clinical efficacy in the process of innovation. This paper introduced his clinical experiences on the treatment of migraine briefly.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"14 5","pages":"Pages 1985-1987"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(13)60014-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76642306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Latest Advancement for Detection Methods of Mycotoxins in Traditional Chinese Medicine","authors":"Feng Xu ,&nbsp;Kong Weijun ,&nbsp;Yang Meihua ,&nbsp;Ouyang Zhen","doi":"10.1016/S1876-3553(13)60011-3","DOIUrl":"10.1016/S1876-3553(13)60011-3","url":null,"abstract":"<div><p>Mycotoxins are secondary metabolites produced by certain fungi, which can trigger cancers, deformity and mutation, and are greatly harmful to cells, kidney, reproductive system and immune system. During harvesting, processing, transportation and storage of the plants, Chinese materia medica (CMM) can be easily contaminated by mycotoxins. Not only can it influence the quality and efficacy of CMM, but also do great harm to human body. Therefore, it seems important and necessary to establish sensitive and accurate methods to detect the mycotoxins in CMM. This paper reviewed the advancement of detection methods for mycotoxins in CMM to provide some references for related studies.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"14 5","pages":"Pages 1944-1952"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(13)60011-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86491447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research on No-Reflow Phenomenon after PCI and the Open and Close of Xuanfu","authors":"Shichao Lv ,&nbsp;Junping Zhang","doi":"10.1016/S1876-3553(13)60013-7","DOIUrl":"10.1016/S1876-3553(13)60013-7","url":null,"abstract":"<div><p>No-Reflow (NR) is the common complication after percutaneous coronary intervention (PCI). It has a complex pathogenesis. Modern medicine has no ideal prevention and treatment method. Through systematic literature review, in the <em>Xuanfu</em> (mysterious mansion) theory, NR is due to the reason that <em>Qi</em> and blood cannot moisten and nourish myocardium. The key is dysfunction of <em>Xuanfu</em>. <em>Xuanfu</em> is both the gate of <em>Qi</em> ascending, descending, exiting and entering movement and the channel of body fluid circulation. The basic pathogenesis of NR is the blockage of <em>Xuanfu</em>. We propose that the method of dredging <em>Xuanfu</em> can be used in the treatment of NR. It is a new thought for the prevention and treatment of NR. It has a significant meaning for increasing the treatment effect of PCI.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"14 5","pages":"Pages 1981-1984"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(13)60013-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89525550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Anti-cancer Traditional Chinese Medicine Injections based on Market Performance","authors":"Yunfeng Lai,&nbsp;Jinjian Lu,&nbsp;Xiuping Chen,&nbsp;Hao Hu,&nbsp;Yitao Wang","doi":"10.1016/S1876-3553(13)60012-5","DOIUrl":"10.1016/S1876-3553(13)60012-5","url":null,"abstract":"<div><p>Traditional Chinese medicine injections (TCMIs) have played vital roles in the treatment of cancer, cardiovascular diseases, virus and so on. This article analyzed the market of anti-cancer TCMIs in China, with special emphasis on <em>Kang'ai</em> Injection, <em>Shenqi Fuzheng</em> Injection, <em>Aidi</em> Injection, <em>Lentinan</em> Injection and Compound <em>Kushen</em> Injection, which presented excellent market performances. An analysis on the technical features and clinical applications of these five anti-cancer TCMIs was also conducted. Finally, we pointed out constraints and possible solutions to the development of anti-cancer TCMIs.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"14 5","pages":"Pages 1958-1962"},"PeriodicalIF":0.0,"publicationDate":"2012-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(13)60012-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90452198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimization Mode of Innovative Chinese Medicine Formulations Based on Traditional Chinese Medicine Hospital Preparations","authors":"Tian Yuanxiang ,&nbsp;Lei Yan ,&nbsp;Cao Hongxin ,&nbsp;Weng Weiliang","doi":"10.1016/S1876-3553(13)60008-3","DOIUrl":"10.1016/S1876-3553(13)60008-3","url":null,"abstract":"<div><p>This study was aimed at investigating the optimization model of innovative Chinese medicine formulations based on traditional Chinese medicine (TCM) hospital preparations. A literature review was conducted to analyze the importance and characteristics of TCM hospital preparations. Then, the optimization process and methods of hospital preparations were summarized and explored. The results showed that hospital preparation is an important and fundamental resource of new drug development, with characteristics of abundant clinical experience, multiple formulations, multiple dosage forms, well-established efficacy and reliable safety. Hospital preparations may provide a rich material foundation for the screening of new drug development, which can shorten the development cycle and reduce research cost. However, there is still a gap between hospital preparations and innovative drugs. Based on our optimization work experiences, the optimization of hospital preparations should comply with the general principles and process of optimizing innovative Chinese medicine formulations, which can be divided into three parts, i.e., optimization of component formulation, optimization of clinical trial protocols and assessment before and after clinical trials. The optimization process should be well focused, so as to facilitate comprehensive optimization. Before optimization, the investigational prescription should undergo qualitative and quantitative evaluation for the first time. Based on the sponsor's final revision, the second qualitative and quantitative evaluation should be performed before the initiation of clinical trials. After clinical trials, the prescription should undergo qualitative and quantitative evaluation for the third time according to the findings of clinical trials. It was concluded that it is possible to provide an optimization model of innovative Chinese medicine formulations based on TCM hospital preparations.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"14 4","pages":"Pages 1831-1834"},"PeriodicalIF":0.0,"publicationDate":"2012-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(13)60008-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89025340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of Three Kinds of Traditional Chinese Therapies on Airway Remodeling in Asthmatic Rats","authors":"Xu Zhaoxia,&nbsp;Li Xueliang,&nbsp;Qian Peng,&nbsp;Li Na,&nbsp;Wang Yiqin,&nbsp;Yan Haixia,&nbsp;Guo Rui,&nbsp;Hao Yiming","doi":"10.1016/S1876-3553(13)60010-1","DOIUrl":"10.1016/S1876-3553(13)60010-1","url":null,"abstract":"<div><p>This paper was aimed at observing the protective effects of traditional Chinese medicine (TCM) varying in therapeutic methods on airway remodeling in bronchial asthma. Three TCM decoctions, representing body resistance-strengthening therapy, lung-diffusing therapy, and combination therapy, were prepared and administrated peroral to asthmatic rats induced by ovalbumin. Eosinophils (EOS) were counted in bronchoalveolar lavage fluid (BALF), and levels of matrix metalloproteinase (MMP-9) and tissue inhibitors of metalloproteinase (TIMP)-1 were detected in serum by ELISA. The results showed that compared with the control group administration of TCM recipes is significantly effective in reducing EOS infiltration into BALF; there was a drop in MMP-1 level and a rise in TIMP-1 level. It was concluded that the three TCM therapies exerted similar protective effects against bronchial asthma. The improvement in airway remodeling can be attributed in part to the inhibiting infiltration of EOS, down-regulating MMP-9 expression and up-regulating TIMP-1 expression.</p></div>","PeriodicalId":101287,"journal":{"name":"World Science and Technology","volume":"14 4","pages":"Pages 1853-1857"},"PeriodicalIF":0.0,"publicationDate":"2012-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1876-3553(13)60010-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88324389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}