RSC Applied Polymers最新文献_第3页

Scalable solution for high dispersibility and low heterogeneity of nuclear-shielding high inorganic filler/polymer composites: a vitrimer via reactive extrusion & mechanochemical intercalation† 高分散性和低非均质性核屏蔽高无机填料/聚合物复合材料的可扩展解决方案：通过反应挤出和机械化学插入的玻璃体†

RSC Applied Polymers Pub Date : 2025-06-18 DOI: 10.1039/D5LP00097A

Shuangxin Lai, Qianyue Tan, Hongli Xie, Jiliang Gong, Liang Xue, Haiping Liu, Ruiqian Zhang, Yijun Li and Shibing Bai

{"title":"Scalable solution for high dispersibility and low heterogeneity of nuclear-shielding high inorganic filler/polymer composites: a vitrimer via reactive extrusion & mechanochemical intercalation†","authors":"Shuangxin Lai, Qianyue Tan, Hongli Xie, Jiliang Gong, Liang Xue, Haiping Liu, Ruiqian Zhang, Yijun Li and Shibing Bai","doi":"10.1039/D5LP00097A","DOIUrl":"https://doi.org/10.1039/D5LP00097A","url":null,"abstract":"Many are pursuing high-performance polymer composites with ultra-high inorganic fillers, focusing on improving inorganic particle dispersion. However, few studies have explored how to address the heterogeneity introduced by inorganic particles after meeting dispersion requirements. This work proposed that resolving the heterogeneity in polymer composites with high inorganic particle content relies on utilizing the movement of polymer chains for self-adaptation. We employed ultra-high-filled tungsten powder (W)/high-density polyethylene (HDPE) composites as the basic model. A vitrimer was introduced to enhance the intensity of mutual diffusion of HDPE chains during static hot pressing. The vitrimer-modified W/HDPE composites (W/HDPE-v) not only ensured the high dispersion of W but also facilitated intense mutual diffusion of the chains through the bond exchange of the vitrimer under thermal action. This process led to the ordered stacking of the C–C main chains and increased the crystallinity of the composites. Through the chains’ mutual diffusion, fluctuations in the modulus of the HDPE matrix were reduced, and the interfacial layer between the HDPE and W underwent continuous dynamic reorganization. This dynamic reorganization achieved heterogeneity reduction. The introduction of the vitrimer also generated regions within the polymer chains that exhibited different steric hindrances, which were significantly influenced by factors such as the crosslinking agent content and external forces. This resulted in a directional bond exchange of the vitrimer and traction on the polymer chains, promoting the self-aggregation of polymer chains and the rejection of inorganic particles. The final composites exhibited good mechanical properties and gamma-ray shielding effects.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 5","pages":" 1216-1229"},"PeriodicalIF":0.0,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lp/d5lp00097a?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145073534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metal oxide cluster-integrated polymer networks for robust solid-state single-ion conduction at high temperatures† 金属氧化物簇集成聚合物网络坚固的固态单离子传导在高温†

RSC Applied Polymers Pub Date : 2025-06-17 DOI: 10.1039/D5LP00125K

Jie Deng, Litao Ma, Lu Liu, Weigang Sun, Yuan Liu and Panchao Yin

{"title":"Metal oxide cluster-integrated polymer networks for robust solid-state single-ion conduction at high temperatures†","authors":"Jie Deng, Litao Ma, Lu Liu, Weigang Sun, Yuan Liu and Panchao Yin","doi":"10.1039/D5LP00125K","DOIUrl":"https://doi.org/10.1039/D5LP00125K","url":null,"abstract":"Ion conduction at high temperatures is critical for the improvement of working efficiency and stability of energy-conversion and -storage devices. Ceramics and highly rigid polymers are generally applied for achieving this; however, their poor processability and mechanical properties hinder their extensive applications. Herein, a sub-nanometer anionic metal oxide cluster ({V6O13[(OCH2)3CR]2}2−) was covalently integrated into polymer networks for high-temperature solid-state conduction of H+ and Li+ single-ion electrolytes. The hexavanadate cluster was functionalized with acrylate groups, and it served as a nanoscale bifunctional crosslinker to copolymerize with poly(ethylene glycol) methacrylate for the fabrication of polymer networks. The associated counter-cations of the immobilized hexavanadate could be fully solvated in the melts of poly(ethylene glycol) for realizing high mobilities, contributing to promising single-ion conductivities and achieving an Li+ transference number of 0.84. According to dielectric spectroscopy studies, the transport of Li+ ions was directly mediated by side chain dynamics. The counter-cations could be feasibly switched for the conduction of various cations, such as H+ and Li+. Meanwhile, the covalent and supramolecular interactions between the polymer and inorganic hexavanadate afforded enhanced stability and robust ionic conduction at temperatures as high as 200 °C. Thus, this work provides versatile platform chemical systems for robust solid-state single-ion conduction at high temperatures.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 5","pages":" 1177-1182"},"PeriodicalIF":0.0,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lp/d5lp00125k?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145073530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Production of gelatin methacrylate by flow chemistry and investigation of its suitability as a biomaterial† 流动化学法制备甲基丙烯酸明胶及其作为生物材料的适用性研究

RSC Applied Polymers Pub Date : 2025-06-12 DOI: 10.1039/D5LP00078E

Pallavi Sengupta, Emma Salisbury, Anil Kumar, Tanja Junkers and Neil R. Cameron

{"title":"Production of gelatin methacrylate by flow chemistry and investigation of its suitability as a biomaterial†","authors":"Pallavi Sengupta, Emma Salisbury, Anil Kumar, Tanja Junkers and Neil R. Cameron","doi":"10.1039/D5LP00078E","DOIUrl":"https://doi.org/10.1039/D5LP00078E","url":null,"abstract":"Biopolymers such as gelatin, hyaluronic acid, and chitin are used in the form of hydrogels as scaffolds for tissue engineering and as bioinks for bioprinting. The biopolymers themselves tend to be weak and hence are usually chemically functionalized to improve their stability and tenacity. The chemical functionalization is currently conducted using batch methods, which are time-consuming, difficult to scale up, and have batch-to-batch variation. Flow chemistry, on the other hand, is more efficient, safer, reproducible, easy to scale up, and can give much higher space–time yields compared to batch reactions. In this study, a flow chemistry protocol was developed for the synthesis of the commonly used biomaterial gelatin methacrylate (GelMA), and the resulting GelMA was used in bioprinting and as a hydrogel in cell culture studies to investigate its ability to support cell attachment and expansion. It was found that conversion of gelatin into GelMA proceeded rapidly and optimally at 60 °C, giving reproducible and high degrees of substitution (65–85%) and high yields in up to 20 minutes of reaction. Scale-up of the reaction was also demonstrated. The resulting GelMA was characterized by oscillatory shear rheometry and was found to be capable of extrusion bioprinting, yielding self-supporting and defect-free hydrogel patterns. The GelMA hydrogels were also found to be able to support the proliferation of primary endometrial cells over 6 days of culture. The GelMA produced by flow chemistry, therefore, was shown to be suitable for use as a bioink and as a hydrogel substrate for cell culture, demonstrating the potential of flow chemistry as an efficient method to produce biomaterials for bioprinting and tissue engineering applications.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 5","pages":" 1204-1215"},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lp/d5lp00078e?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145073533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cryopreservation and post-thaw differentiation of monocytes enabled by macromolecular cryoprotectants which restrict intracellular ice formation† 通过限制细胞内冰形成的大分子冷冻保护剂实现单核细胞的低温保存和解冻后分化。

RSC Applied Polymers Pub Date : 2025-06-09 DOI: 10.1039/D5LP00131E

Natalia Gonzalez-Martinez, Ruben M. F. Tomás, Akalabya Bissoyi, Agnieszka Nagorska, Alexandru Ilie and Matthew I. Gibson

{"title":"Cryopreservation and post-thaw differentiation of monocytes enabled by macromolecular cryoprotectants which restrict intracellular ice formation†","authors":"Natalia Gonzalez-Martinez, Ruben M. F. Tomás, Akalabya Bissoyi, Agnieszka Nagorska, Alexandru Ilie and Matthew I. Gibson","doi":"10.1039/D5LP00131E","DOIUrl":"10.1039/D5LP00131E","url":null,"abstract":"THP-1 is a monocytic cell line which can differentiate into macrophage and dendritic cells, widely used in immunology. Immune cells are particularly sensitive to cryopreservation, leading to low recovery and/or reduced differentiation capacity compared to non-frozen cells. Current cryopreservation protocols are unsuitable to cryopreserve THP-1 cells in ‘assay-ready’ format, due to the time and resource intensive culturing steps required post-thaw to recover functional cells. We report the cryopreservation of THP-1 cells in vial and multi-well plate format, with significantly enhanced recovery compared to commercial cryoprotectants. This was achieved using macromolecular cryoprotectants (polyampholytes and ice nucleators) which doubled post-thaw recovery relative to DMSO-alone and improved macrophage phenotype post-differentiation comparable to non-frozen controls. Cryo-Raman microscopy demonstrated that the polyampholytes reduced intracellular ice formation compared to DMSO-alone. These results will enable routine banking and ‘assay-ready’ THP-1 cells direct from the freezer, accelerating immunological research.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 4","pages":" 990-1001"},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12147442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144277281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High barrier bio-nanocomposite films of ethyl cellulose integrated with modified nanocellulose: effect of nanocellulose's substituted side chains on film performance† 改性纳米纤维素与乙基纤维素合成的高屏障生物纳米复合膜：纳米纤维素取代侧链对膜性能的影响

RSC Applied Polymers Pub Date : 2025-06-09 DOI: 10.1039/D4LP00356J

Supattra Klayya, Patcharee Pripdeevech, Emiliano Bilotti, Han Zhang and Nattakan Soykeabkaew

{"title":"High barrier bio-nanocomposite films of ethyl cellulose integrated with modified nanocellulose: effect of nanocellulose's substituted side chains on film performance†","authors":"Supattra Klayya, Patcharee Pripdeevech, Emiliano Bilotti, Han Zhang and Nattakan Soykeabkaew","doi":"10.1039/D4LP00356J","DOIUrl":"https://doi.org/10.1039/D4LP00356J","url":null,"abstract":"Bio-based packaging films with good barrier properties to preserve quality, ensure safety, and extend the shelf-life of food products are in great demand as our society becomes more environmentally conscious. Herein, entirely bio-based nanocomposite films of the ethylcellulose (EC) matrix, reinforced with modified nanofibrillated cellulose (mNFC), have been studied. The NFC modification consisted in a microwave-assisted esterification reaction with three different acids – lactic acid (LA), lauric acid (LU), and stearic acid (SA) – of varying carbon chain lengths, in three solvents (water, ethanol, and ethyl acetate). The highest degree of substitution (DS) for mNFC-LA was achieved in ethanol, while mNFC-LU and mNFC-SA showed the maximum DS (up to 1.22) in ethyl acetate. The success of NFC surface modification was confirmed by titration, FTIR, XRD, SEM, and nanocellulose dispersion behavior. The films of EC-based nanocomposites were prepared by solvent casting and then examined for surface morphology, microstructures, mechanical properties, surface properties and barrier properties against water vapor and oxygen transmission. The findings revealed that integrating mNFC into EC can greatly improve the properties of the films due to their good compatibility, good dispersion ability, and strong interface, which is influenced by the substituted side chain on the mNFC surface. For the best side chain length (3 carbon atoms), mNFC-LA increased the tensile strength of the EC film by up to 130% while reducing the oxygen transmission rate (OTR) by 98%, making it a viable and environmentally benign alternative to PET films. This research offers insights into employing various modified nanocellulose to improve biopolymer-based films for high-barrier packaging and coating applications.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 5","pages":" 1244-1257"},"PeriodicalIF":0.0,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lp/d4lp00356j?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145073561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vinylene-bridged naphthalenediimide-based dual-acceptor copolymers for thin-film transistors and solar steam generation† 用于薄膜晶体管和太阳能蒸汽产生的乙烯桥接萘二酰亚胺基双受体共聚物

RSC Applied Polymers Pub Date : 2025-06-06 DOI: 10.1039/D5LP00136F

Chia-Yang Lin, Guan-Lin Wu, Ting-Yu Wang, Waner He, Ying-Sheng Wu, Shunsuke Imaoka, Shohei Shimizu, Wen-Chang Chen, Yoshimitsu Sagara, Chu-Chen Chueh and Tsuyoshi Michinobu

{"title":"Vinylene-bridged naphthalenediimide-based dual-acceptor copolymers for thin-film transistors and solar steam generation†","authors":"Chia-Yang Lin, Guan-Lin Wu, Ting-Yu Wang, Waner He, Ying-Sheng Wu, Shunsuke Imaoka, Shohei Shimizu, Wen-Chang Chen, Yoshimitsu Sagara, Chu-Chen Chueh and Tsuyoshi Michinobu","doi":"10.1039/D5LP00136F","DOIUrl":"https://doi.org/10.1039/D5LP00136F","url":null,"abstract":"Recent studies have shown that introducing vinylene bridges into naphthalenediimide (NDI)-based dual-acceptor copolymers is an effective strategy to improve backbone coplanarity and charge transport properties in organic field-effect transistors (OFETs). However, their potential as multifunctional materials for broader optoelectronic applications remains unexplored. In this study, we designed and synthesized four vinylene-bridged NDI (vNDI)-based conjugated polymers containing benzothiadiazole (S), benzotriazole (N), triazolobenzothiadiazole (NS), and benzobistriazole (NN) as second acceptors. Structural analysis revealed that the backbone conformation and electron-withdrawing ability of the acceptors significantly influence optical and electronic properties. Among them, vNDI-NS exhibited the narrowest optical bandgap (1.05 eV), while vNDI-N displayed the highest ambipolar mobility in OFETs, attributed to enhanced crystallinity and improved π–π stacking. Furthermore, these polymers were applied as photothermal membranes in solar steam generation (SSG) devices. Films based on vNDI-NS and vNDI-NN achieved solar-to-vapor conversion efficiencies of 58.3% and 56.4%, respectively, under 1 sun illumination. This study expands the applications of vNDI-based polymers beyond OFETs, providing a dual-functional platform combining electrical and photothermal performance.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 4","pages":" 1011-1018"},"PeriodicalIF":0.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lp/d5lp00136f?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of all-organic nanodielectrics reinforced with electrospun polymer fibres for capacitive energy storage 电纺丝聚合物纤维增强全有机纳米电介质的制备及其电容储能性能

RSC Applied Polymers Pub Date : 2025-06-04 DOI: 10.1039/D5LP00029G

Stavros X. Drakopoulos, Konstantinos Loukelis, Marios Triantafyllou-Rundell, Constantinos C. Stoumpos, Maria Chatzinikolaidou and Georgios C. Psarras

{"title":"Fabrication of all-organic nanodielectrics reinforced with electrospun polymer fibres for capacitive energy storage","authors":"Stavros X. Drakopoulos, Konstantinos Loukelis, Marios Triantafyllou-Rundell, Constantinos C. Stoumpos, Maria Chatzinikolaidou and Georgios C. Psarras","doi":"10.1039/D5LP00029G","DOIUrl":"https://doi.org/10.1039/D5LP00029G","url":null,"abstract":"Advancements in all-organic dielectrics are crucial for electrical energy storage devices and flexible electronics due to their low cost and easier processability compared to inorganic materials for similar applications. In the present work, epoxy-based all-organic nanodielectric materials were developed for capacitive energy storage applications. To be employed as fillers, nanofibres were developed by means of electrospinning, utilizing two polymers, polyvinyl alcohol (PVA) and chitosan (CS). Three cases were examined with nanofibers consisting of pure PVA (5% w/w in epoxy) and PVA : CS in weight ratios of 5 : 1 and 5 : 2 (both 4% w/w in epoxy). The morphological, structural, thermal and dielectric properties of the developed polymer nanodielectric materials were extensively investigated, with a clear focus on their ability to store and recover energy in a capacitor configuration. The presence of CS appeared to significantly increase the dielectric permittivity and restrict charge transport, which is beneficial for energy recovery efficiency, attributed to its strongly insulating nature.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 4","pages":" 960-972"},"PeriodicalIF":0.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lp/d5lp00029g?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Touch transfer of microorganisms on polymer surfaces† 触摸转移的微生物在聚合物表面†

RSC Applied Polymers Pub Date : 2025-06-03 DOI: 10.1039/D5LP00110B

Meng-Chen Chiang, Carla Steppan, Ted W. Deisenroth, Rupert Konradi, Todd Emrick and Jessica D. Schiffman

{"title":"Touch transfer of microorganisms on polymer surfaces†","authors":"Meng-Chen Chiang, Carla Steppan, Ted W. Deisenroth, Rupert Konradi, Todd Emrick and Jessica D. Schiffman","doi":"10.1039/D5LP00110B","DOIUrl":"https://doi.org/10.1039/D5LP00110B","url":null,"abstract":"The transfer of bacteria between dry, high-touch surfaces in healthcare settings is a key contributor to hospital-acquired infections (HAIs). In this study, we systematically investigated the relationship between the chemistry of polymer surfaces and the corresponding touch-transfer of microorganisms. The polymers investigated included polymer zwitterions, PEGylated polymers, poly(tetrafluoroethylene) (PTFE), and polystyrene (PS). Water contact angle measurements confirmed the breadth of surface energies of these polymers, ranging from <25° (polymer zwitterion) to >100° (PTFE). A touch transfer model was developed to study bacteria transfer by “finger touches” on an agar plate. The amount of Escherichia coli (E. coli) or Staphylococcus aureus (S. aureus) transferred after each touch was quantified via plate counting. For E. coli, the transfer rate was ∼29% on zwitterionic copolymer surfaces, whereas PS exhibited a much higher rate of ∼67%. For S. aureus, the transfer rate was ∼17% for the polymer zwitterion and ∼100% for PS. The low transfer rates from the polymer zwitterion were comparable to those of PTFE (∼19% for E. coli and ∼17% for S. aureus). These findings demonstrate the role of polymer composition and surface chemistry in bacterial transfer and provide insights for designing materials that effectively minimize microbial transmission in healthcare environments.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 4","pages":" 1002-1010"},"PeriodicalIF":0.0,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lp/d5lp00110b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144641108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Graphene inks for printing based on thermoresponsive ABC triblock terpolymer gels† 基于热敏ABC三嵌段三元共聚物凝胶的印刷用石墨烯油墨。

RSC Applied Polymers Pub Date : 2025-06-02 DOI: 10.1039/D5LP00071H

Xu Liu, Bailin Feng, Stefano Tagliaferri, Anna P. Constantinou, Alexandra E. Porter, Cecilia Mattevi and Theoni K. Georgiou

引用次数: 0

Biomolecule-modified synthetic polymers for wound healing and orthopaedic applications 用于伤口愈合和矫形外科的生物分子修饰合成聚合物

RSC Applied Polymers Pub Date : 2025-05-30 DOI: 10.1039/D5LP00074B

Eun Ju Park, Jiayi Guo, Yew Chin Teo and Peili Teo

{"title":"Biomolecule-modified synthetic polymers for wound healing and orthopaedic applications","authors":"Eun Ju Park, Jiayi Guo, Yew Chin Teo and Peili Teo","doi":"10.1039/D5LP00074B","DOIUrl":"https://doi.org/10.1039/D5LP00074B","url":null,"abstract":"Synthetic polymers play an important role in medical devices such as implants, wound dressings and catheters since the first use of polyethylene in bone and cartilage implants in the 1940s. Since then, many more synthetic polymers have been used in medical devices for applications ranging from orthopaedic implants, wound care products, heart valves, and stents to tissue grafts. However, nearly all the polymers used in these devices are bioinert, except for some that are biodegradable such as polyesters. These polymers generally do not confer bioactivity on their own and need additional stimuli such as through modification with biomolecules or blending with bioadditives. We term polymers chemically modified with biomolecules “Biohybrid Polymers” and they represent a new class of biomaterials that are purely synthetic. These biomaterials possess properties required for use in applications such as tissue engineering and medical device fabrication. In this review, we explore the different types of biohybrid polymers that have been reported for use in skin, bone and cartilage tissue engineering with brief descriptions of their chemical synthesis methods. The materials are categorised based on their targeted applications in wound care or orthopaedics to help readers understand what are the potential materials that may be used for each type of tissue being regenerated.","PeriodicalId":101139,"journal":{"name":"RSC Applied Polymers","volume":" 5","pages":" 1124-1144"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/lp/d5lp00074b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145073519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0