{"title":"Alternatives to homologous blood transfusion","authors":"Sharhabil S. Ammus MD, Bruce A. Lenes MD","doi":"10.1016/0278-6222(88)90054-X","DOIUrl":"10.1016/0278-6222(88)90054-X","url":null,"abstract":"","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 2","pages":"Pages 231-240"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90054-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73565599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of plasticizers on red blood cells and platelets during storage","authors":"Alan A. Waldman PhD","doi":"10.1016/0278-6222(88)90008-3","DOIUrl":"10.1016/0278-6222(88)90008-3","url":null,"abstract":"<div><p>The introduction of plastic bags into routine use in Blood Banks began a revolution in how human blood and blood components were prepared, stored and used.</p><p>The plastic film is not inert, however, and plasticizers added to increase flexibility of the bags can be extracted into the stored components. In this report, the characteristics of this extraction, and the effect of exposure to the extracted material on the components in storage, is reviewed and discussed.</p><p>Particular emphasis is placed on the organic compound, di(2-ethylhexyl) phthalate (DEHP), which can constitute up to 40% of the weight of classic PVC films. DEHP has been shown to interact both with erythrocytes, where the interaction aids in preservation of erythrocyte integrity, and with platelets, where the interaction has been shown to be deleterious to maintenance of platelet function.</p><p>The advantages and disadvantages of plastics formulated without DEHP are also presented and evaluated.</p></div>","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 3","pages":"Pages 317-330"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90008-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73072410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"AIDS and treatment of hemophilia patients","authors":"Margaret V. Ragni MD","doi":"10.1016/0278-6222(88)90050-2","DOIUrl":"10.1016/0278-6222(88)90050-2","url":null,"abstract":"","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 2","pages":"Pages 173-191"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90050-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87093925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G.J. Tijhuis, J.J. van Doormaal MD, L. Rijskamp, C.Th.Smit Sibinga MD, PhD, H. Doorenbos MD, PhD
{"title":"Plasma exchange and low-density lipoprotein filtration therapy in heterozygous familial hypercholesterolemia","authors":"G.J. Tijhuis, J.J. van Doormaal MD, L. Rijskamp, C.Th.Smit Sibinga MD, PhD, H. Doorenbos MD, PhD","doi":"10.1016/0278-6222(88)90029-0","DOIUrl":"10.1016/0278-6222(88)90029-0","url":null,"abstract":"<div><p>We studied serum lipids during and shortly after a single plasma exchange (PE) on seven separate occasions in four patients, and during long-term treatment by regular PE in three patients with heterozygous familial hypercholesterolemia. Also, a comparison was made for efficacy in lipid and apolipoprotein removal between long-term weekly PE therapy and three consecutive weekly low-density lipoprotein (LDL) filtration procedures in one patient. PE was done by intermittentflow centrifugation (IFC) with Haemonetics V50 apparatus, exchanging one plasma volume. LDL filtration consisted of a cascade PE, in which the plasma was separated by IFC and the LDL fraction was subsequently removed by membrane filtration over a polyalcohol filter (Evaflux<sup>®</sup>). From the results, we concluded that (1) LDL cholesterol is reduced about 50% by both methods; (2) after PE, high-density lipoprotein (HDL) cholesterol does not increase during the first two hours, but rises thereafter faster than LDL cholesterol and can reach baseline within three days; (3) by LDL filtration, HDL cholesterol decreases about 30% less than LDL cholesterol and tends to increase above the starting levels found during weekly PE treatment; (4) the reductions in LDL and HDL cholesterol are larger than those in apolipoprotein B and A-I, respectively, in both methods; and (5) connection of the LDL filter device to the Haemonetics V50 system simplifies the cascade procedure, resulting in a single needle approach and avoidance of hemolysis in the primary plasma separation.</p></div>","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 1","pages":"Pages 29-34"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90029-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90871935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Invitation to the 3rd International Congress of the World Association of Apheresis","authors":"","doi":"10.1016/0278-6222(88)90009-5","DOIUrl":"https://doi.org/10.1016/0278-6222(88)90009-5","url":null,"abstract":"","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 3","pages":"Page 331"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90009-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136556063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Molecular mechanisms of the red cell storage lesion","authors":"William C. Horne PhD","doi":"10.1016/0278-6222(88)90002-2","DOIUrl":"10.1016/0278-6222(88)90002-2","url":null,"abstract":"<div><p>Preserved erythrocytes undergo several changes during storage, collectively referred to as the storage lesion, which reduce the effectiveness of stored erythrocytes following transfusion. This review describes the mechanisms leading to these changes, so far as they are known, and discusses the relationship of the changes to one another and how they contribute to the diminished function of stored erythrocytes.</p></div>","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 3","pages":"Pages 259-273"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90002-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84439231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Automated plasmapheresis with a nylon membrane","authors":"J.C. Faber MD , A.J. Reppucci BA, SBB(ASCP) , J.M. Mathias MS , J.P. Hoffmann ChemEng","doi":"10.1016/0278-6222(88)90013-7","DOIUrl":"10.1016/0278-6222(88)90013-7","url":null,"abstract":"<div><p>A new nylon membrane is an effective alternate to the original polycarbonate membrane in the Autopheresis-C<sup>®</sup> plasmapheresis system. With the original membrane some donors were noted to have reduced plasma flow rates (less than 15 mL/min) and therefore increased plasmapheresis times. In the study reported here, 30 of these low-flow donors were matched for age, sex, and blood group with 32 normal-flow donors, and all underwent plasmapheresis using the new nylon membrane. No significant differences could be found between the groups in apheresis time, plasma flow rate, amount of plasma donated or amount of Factor VIII:C or other biological parameters measured in the plasma.</p></div>","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 4","pages":"Pages 347-350"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90013-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89914501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of AIDS on blood donors","authors":"Peter L. Page MD","doi":"10.1016/0278-6222(88)90055-1","DOIUrl":"10.1016/0278-6222(88)90055-1","url":null,"abstract":"","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 2","pages":"Pages 241-256"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90055-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79607361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Björeman , E. Björsell-Östling , J. Schollin , B. Sandström , T. Ström
{"title":"Case report: Thrombotic thrombocytopenic purpura during pregnancy: Treatment with plasma substitution","authors":"M. Björeman , E. Björsell-Östling , J. Schollin , B. Sandström , T. Ström","doi":"10.1016/0278-6222(88)90039-3","DOIUrl":"10.1016/0278-6222(88)90039-3","url":null,"abstract":"<div><p>Thrombotic thrombocytopenic purpura (TTP) is presently regarded as one of the most clearcut indications for plasma exchange (PE). We describe a young woman with TTP during pregnancy who initially received PE but during the last months of her pregnancy needed only infusions of plasma to control her TTP. Furthermore, during his first days of life, her newborn son showed signs of microangiopathic hemolytic anemia (MAH). These signs rapidly vanished after an exchange transfusion.</p></div>","PeriodicalId":101030,"journal":{"name":"Plasma Therapy and Transfusion Technology","volume":"9 1","pages":"Pages 89-94"},"PeriodicalIF":0.0,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0278-6222(88)90039-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74969409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}