{"title":"From lab to field: Nano-biosensors for real-time plant nutrient tracking","authors":"Anjali Bharti, Utkarsh Jain, Nidhi Chauhan","doi":"10.1016/j.plana.2024.100079","DOIUrl":"10.1016/j.plana.2024.100079","url":null,"abstract":"<div><p>The growing world’s population and increasing demand for food production can lead to major food security and safety challenges. The different varieties of pathogens such as bacteria, fungi, viruses, pests, insects, etc. are the major causes of crop loss. So, the implementation of biosensors in the field of agriculture can be a beneficial tool to solve this problem. Biosensors can help to promote sustainable food production by the early detection of pathogens, fertilizers, herbicides, pesticides, moisture, and diseases in crops and animals, as well as the presence of heavy metal ions, and toxins. Additionally, it can also help to measure the different parameters including soil pH, chlorophyll content, photosynthetic content, protein content, and total nutrient uptake (macronutrients and micronutrients) by the plants, etc. With the implementation of these biosensors, farmers can increase crop yields, optimize fertilization techniques, and preserve resources by detecting and measuring particular nutrients. The implementation of Artificial Intelligence (AI) and Internet of Things (IoT) technology greatly transforms the state of traditional agriculture by addressing various challenges, such as pest management and post-harvest management issues. In this review, different types of biosensors are utilized in the agricultural field for monitoring various parameters related to plants but some obstacles need to be addressed. This article mainly focuses on the various types of biosensors including electrochemical biosensors, optical biosensors, plant wearable biosensors, etc., and their applications and advantages along with the adoption of AI and IoT technology in smart- farming are also discussed.</p></div>","PeriodicalId":101029,"journal":{"name":"Plant Nano Biology","volume":"9 ","pages":"Article 100079"},"PeriodicalIF":0.0,"publicationDate":"2024-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773111124000226/pdfft?md5=c21f0da14ecab544a5ee6e154ac05476&pid=1-s2.0-S2773111124000226-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141277859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Otávio Augusto L. dos Santos , Mayara Santana dos Santos , Sérgio Antunes Filho , Bianca Pizzorno Backx
{"title":"Nanotechnology for the control of plant pathogens and pests","authors":"Otávio Augusto L. dos Santos , Mayara Santana dos Santos , Sérgio Antunes Filho , Bianca Pizzorno Backx","doi":"10.1016/j.plana.2024.100080","DOIUrl":"https://doi.org/10.1016/j.plana.2024.100080","url":null,"abstract":"<div><p>Agriculture is the primary food source and fundamental for human survival. However, managing pests and diseases of crops remains a challenge. Moreover, climate change events such as drought, soil depletion, and low nutrient use efficiency are significant barriers to global food security. Nanotechnology has emerged as a possibility for resolving these issues. Nanomaterials have different properties compared to their bulk forms, which allows for a wide range of new applications. An urgent demand is for the combat against pests and pathogens that cause significant losses to different cultivars, and many are still acquiring resistance, which makes this fight a challenge. Many nanomaterials have demonstrated the ability to combat such pathogens, raising their potential application. In this review, we will discuss the use of nanomaterials in combating a wide variety of pathogens and pests that constantly affect different cultivars around the world. The efficiency of the treatments varied depending on the type of nanomaterial as well as characteristics such as size and morphology. Furthermore, the dosage was another determining factor in the outcome, so that there were relevant results with improved plant development and performance. Also, we demonstrated recent advances in controlling virus infections that affect a wide variety of cultivars. We also discuss the potential to combat the most common pests and the possible mechanisms of action of these nanomaterials, which make them capable of affecting a broad spectrum of organisms. Nanomaterials probably act through different pathways, and the resulting pathways would allow the control of these pests and diseases. However, the threshold between toxicity and beneficial effects is still difficult to determine, and the resulting toxicity varied among the different cultivars reviewed. We present the challenges that still exist and perspectives for the use and commercialization of nanoproducts.</p></div>","PeriodicalId":101029,"journal":{"name":"Plant Nano Biology","volume":"8 ","pages":"Article 100080"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773111124000238/pdfft?md5=b9155bd0b9e85a6421f6d6f30ad11e36&pid=1-s2.0-S2773111124000238-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141313791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Murraya koenigii plant extract mediated green synthesis of metallic nanoparticles and their applications: A review","authors":"Amit Bhardwaj, Ritika, Arun K. Singh","doi":"10.1016/j.plana.2024.100076","DOIUrl":"10.1016/j.plana.2024.100076","url":null,"abstract":"<div><p>The utilization of natural biomolecules in <em>Murraya koenigii</em> (MK) plant extracts attracted significant attention of the scientific community for the synthesis of single and bi-metallic nanoparticles (NPs) in recent years. The specific biomolecules and natural phenolic acids (apigenin, quercetin, eugenol, naringnin, etc.) in this plant extract act as reducing/capping and stabilizing agents during the green synthesis of stabilized metallic NPs (Ag, Cu, Zn, Se, Fe etc.) with the use of their respective metal ion precursor solution. In this review study, the information about phytochemical constituents in the extracts of MK plant and their utility in synthesis of various single and bi-metallic NPs are discussed. The physico-chemical characterization of the synthesized various single and bi-metallic NPs are also discussed along with their anti-cancer and anti-bacterial ability. In addition, unresolved issues related to nanoparticle synthesis at large scale and expected improvement for future studies are also highlighted which are highly needful for application in the real environment.</p></div>","PeriodicalId":101029,"journal":{"name":"Plant Nano Biology","volume":"8 ","pages":"Article 100076"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773111124000196/pdfft?md5=6f6876c903013865f9dab406c8560e5b&pid=1-s2.0-S2773111124000196-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141026462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fascinating aspects of nanosilicon enabled plant stress tolerance – A comprehensive review","authors":"Sapna Grewal , Rekha Boora , Santosh Kumari , Rajesh Thakur , Sonia Goel","doi":"10.1016/j.plana.2024.100077","DOIUrl":"10.1016/j.plana.2024.100077","url":null,"abstract":"<div><p>The establishment of a resilient and enduring agricultural production system is important in order to meet the global need for food. Due to dramatic climatic changes and growing population pressure, traditional chemical-based farming approaches have proven inefficient. Globally, abiotic stresses have a substantial impact on crop yields across many crops. The use of silicon nanoparticles (nSi) has gained popularity in the last few years as a means to alleviate abiotic stress. The addition of nano Si as a supplement has been found to mitigate stress under adverse environmental conditions and promote the growth as well as overall development of plants. Its rehabilitative properties are associated with increased activities of antioxidant enzymes, preserving the balance between the production and elimination of reactive oxygen species. The accumulation and/or absorption of nSi in a variety of crops, along with its mechanism of action, are discussed in this study. These factors are associated with enhanced plant growth and tolerance capacities, which support sustainable agriculture. In summary, this review highlights the significance of nano-enabled methods using nSi for enhancing crop tolerance against abiotic stresses and the potential to address worldwide food security concerns.</p></div>","PeriodicalId":101029,"journal":{"name":"Plant Nano Biology","volume":"8 ","pages":"Article 100077"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773111124000202/pdfft?md5=528d15442398b37275b3ccc3a2cf89f5&pid=1-s2.0-S2773111124000202-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141139873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rachna Gupta , Parth Malik , Ruma Rani , Raghu Solanki , Rakesh Kumar Ameta , Vibhuti Malik , Tapan Kumar Mukherjee
{"title":"Recent progress on nanoemulsions mediated pesticides delivery: Insights for agricultural sustainability","authors":"Rachna Gupta , Parth Malik , Ruma Rani , Raghu Solanki , Rakesh Kumar Ameta , Vibhuti Malik , Tapan Kumar Mukherjee","doi":"10.1016/j.plana.2024.100073","DOIUrl":"10.1016/j.plana.2024.100073","url":null,"abstract":"<div><p>Nature friendly and sustainable practices have been the prominent aspects reviving the modern agricultural practices. Development of broad spectrum insecticides with the minimal use, maximum efficacy and least environmental deterioration are swiftly emerging as reliable measures. Analogous to drug delivery in animal and human cells, nanocarriers are swiftly emerging as biocompatible and nature friendly aids for pesticide delivery to the agricultural crops. These practices manifest a higher importance for the agriculturally intensive global economies, wherein substantial livelihood means are eventually dependent on agriculture. Amicably transcended from the extraordinary investigational success for drug delivery, trafficking of pesticides through nanoemulsions has emerged as a boost to safeguard the environment and aquatic habitats in particular. The nanoemulsions, with the option of varying surfactant and co-surfactants, engineer the slow release of pesticides which could be targeted for the pest specific elimination. The outcomes have already eased the farmer’s economy besides significantly moderating the toxicity. The threat to soil and surrounding water bodies has been the most significant, wherein almost 90% of the unaided pesticide used to run off as excessive chemical load in the soils or water bodies. The constitutional robustness of emulsions with varied hydrophilic-lipophilic balances and surfactant-co-surfactant stoichiometries have been the distinguishing aspect for the pesticide delivery to the crops. With such insights, this review article focuses on emulsification, the distinguishing working principles, physicochemical characterization driven performance control parameters and finally a discussion of past five year attempts encompassing nanocarrier mediated pesticide delivery for sustainable agriculture and reduced environmental stress.</p></div>","PeriodicalId":101029,"journal":{"name":"Plant Nano Biology","volume":"8 ","pages":"Article 100073"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773111124000160/pdfft?md5=530adc79815178f7294214c85067264d&pid=1-s2.0-S2773111124000160-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140771989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of sonication time in nanoparticle synthesis on the nutrition and growth of wheat (Triticum aestivum L.) plant","authors":"Guzin Tombuloglu , Yassine Slimani , Huseyin Tombuloglu , Moneerah Alsaeed , Emine Akyuz Turumtay , Huseyin Sozeri , Sultan Akhtar , Munirah A. Almessiere , Halbay Turumtay , Abdulhadi Baykal","doi":"10.1016/j.plana.2024.100075","DOIUrl":"https://doi.org/10.1016/j.plana.2024.100075","url":null,"abstract":"<div><p>Nanotechnology in agricultural applications is promising in improving plant nutrition and yield, pest control, and gene delivery. However, the method to synthesize nanoparticles or nanocomposites (NCs) can play a crucial role in determining the characteristics of NCs, such as size and morphology, which may be critical factors affecting plant nutrition and NCs` potential toxicity. This study elucidates the effect of sonication time in synthesizing NCs on its characteristics and plant use efficiency. For this purpose, a hard/soft nanocomposite (NC) (CoFe<sub>2</sub>O<sub>4</sub>/Ni<sub>0.8</sub>Cu<sub>0.1</sub>Zn<sub>0.1</sub>Fe<sub>2</sub>O<sub>4</sub>) was sonochemically synthesized at different sonication times (20 and 60 minutes) and comprehensively characterized. They were hydroponically applied to wheat seedlings (50, 100, 200, 400, and 800 mg/L). The physiological, morphological, and nutritional status of the seedlings were determined. The results showed that an increase in sonication time decreased the mean NC size: 26.7 nm (20 minutes) and 17.4 nm (60 minutes). Photosynthetic parameters, growth, and biomass were gradually reduced with the increasing NC concentrations, revealing their toxic effect. However, treating NCs at 60 min significantly improved the average root length, suggesting its beneficial role for plant growth at the germination stage. The content of elements in the composition of the NCs (Fe, Zn, Co, Ni, and Cu) was remarkably higher in the NC-treated roots compared to the untreated controls. In addition, 60 minutes of preparation showed better plant uptake than 20 minutes. This is the first study to evaluate the effect of sonication time in the preparation of NC on plant nutrition and their fate in plants.</p></div>","PeriodicalId":101029,"journal":{"name":"Plant Nano Biology","volume":"8 ","pages":"Article 100075"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773111124000184/pdfft?md5=db582601c6ede1a6f7cd44e9533aa3ef&pid=1-s2.0-S2773111124000184-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140905278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vermiculture-based molybdenum oxide nanoparticles synthesis, optimization, characterization and its impact on seed germination and seedling characteristics in green gram (Vigna radiata)","authors":"Suganya Paulraj , Krishnamoorthi Raman , Kwang-sun Kim , Mahalingam Pambayan Ulagan","doi":"10.1016/j.plana.2024.100074","DOIUrl":"https://doi.org/10.1016/j.plana.2024.100074","url":null,"abstract":"<div><p>Here, we report the biosynthesis of molybdenum oxide (Mo<sub>5</sub>O<sub>14</sub>) nanoparticles (NPs) by co-precipitation methods using various vermiculture-based extracts and their impact on seed germination in <em>Vigna radiata</em>. The synthesis of Mo<sub>5</sub>O<sub>14</sub> NPs was initially characterized by a color change from yellow to white and a surface plasmon resonance (SPR) peak at 360 nm in UV–visible spectroscopic analysis. In addition, X-ray diffraction (XRD) data revealed that the Mo<sub>5</sub>O<sub>14</sub> NPs were crystalline with a tetragonal structure and a size of 35.32–41.86 nm. Furthermore, fourier transform infrared (FTIR) analysis of NPs absorption bands revealed the presence of unique functional groups, such as -OH stretching, CH<sub>2</sub> stretching, and primary amide groups, providing strong evidence that the native protein served to a reduce, cap, and stabilize Mo<sub>5</sub>O<sub>14</sub> NPs. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images revealed that the ultrastructural profile of Mo<sub>5</sub>O<sub>14</sub> NPs formed rod particles with an average particle length of 102 nm and width of 33 nm. The energy dispersive X-ray (EDX) pattern analysis confirmed the presence of Mo and O ions. Finally, the effects of Mo<sub>5</sub>O<sub>14</sub> NPs on <em>Vigna radiata</em> seed fresh and dry biomass characteristics, root and shoot length, and seed germination were investigated, and it was found that a significant increase in the seed germination rate of all seven vermiculture-based Mo<sub>5</sub>O<sub>14</sub> NPs was observed at 200 ppm. Consequently, our work provides a step forward in the development of vermiculture-based Mo<sub>5</sub>O<sub>14</sub> NPs as a promising green agrochemical nano-fertilizer.</p></div>","PeriodicalId":101029,"journal":{"name":"Plant Nano Biology","volume":"8 ","pages":"Article 100074"},"PeriodicalIF":0.0,"publicationDate":"2024-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773111124000172/pdfft?md5=b3c4657370d62de54068b6fdc0b1cf34&pid=1-s2.0-S2773111124000172-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140638727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pradnya V. Patil , Nisha A. Nerlekar , Aviraj R. Kuldeep , Pradnya P. Patil , Prafull B. Dandge , Tukaram D. Dongale , Padma B. Dandge , Gajanan S. Rashinkar
{"title":"Terminalia bellirica (Gaertn.) Roxb. extract-mediated green synthesis of magnesium oxide nanoparticles for multifunctional applications","authors":"Pradnya V. Patil , Nisha A. Nerlekar , Aviraj R. Kuldeep , Pradnya P. Patil , Prafull B. Dandge , Tukaram D. Dongale , Padma B. Dandge , Gajanan S. Rashinkar","doi":"10.1016/j.plana.2024.100069","DOIUrl":"https://doi.org/10.1016/j.plana.2024.100069","url":null,"abstract":"<div><p>Green synthesis has emerged as a pivotal facet of nanotechnology, garnering significant attention for its inherent safety and eco-friendly attributes. This study presents a novel approach utilizing phytochemicals derived from <em>Terminalia bellirica</em> (Gaertn.) Roxb. fruit extract for the environmentally benign synthesis of magnesium oxide (MgO) nanoparticles. The resultant MgO nanoparticles were comprehensively characterized using UV–visible spectroscopy, X-ray Diffractometer (XRD), Fourier Transform Infrared Spectroscopy (FTIR), Energy dispersive X-ray (EDX), and High-Resolution-Transmission Electron Microscope (HR-TEM). The synthesized MgO nanoparticles exhibited remarkable stability, evidenced by zeta potential of −8.84 mV and an average size of 73.41 nm. In an eco-physiological context, the application of MgO nanoparticles at a concentration of 5 mg/100 ml significantly enhanced shoot length (7.94±0.70 cm), root length (8.44±0.53 cm), moisture content (97.16±0.83%), and chlorophyll expression (18.34±0.99 mg/g fresh weight (FW)) in <em>Trigonella foenum-graecum</em> seedlings. Furthermore, the MgO nanoparticles demonstrated biocompatibility with soil bacteria and exhibited potent photocatalytic activity, achieving a 42% degradation efficiency of the organic dye methyl orange under UV irradiation for 60 minutes. In the realm of biomedical applications, MgO nanoparticles displayed dose-dependent cytotoxicity against human breast cancer cells (MCF-7), with an IC<sub>50</sub> value of 37.39±0.05 µg/ml. Remarkably, MgO nanoparticles were also harnessed for their memcapacitive properties, showcasing excellent non-volatile memory characteristics, including endurance for 15,000 cycles and retention for 4000 seconds. In summary, this study underscores the multifunctional prowess of MgO nanoparticles synthesized through <em>Terminalia bellirica</em> fruit extract, spanning applications in plant physiology, environmental remediation, cancer therapeutics, and nanoelectronics. The environmentally conscious synthesis approach and diverse functionalities presented herein position these nanoparticles as future promising candidates for sustainable and versatile technological advancements.</p></div>","PeriodicalId":101029,"journal":{"name":"Plant Nano Biology","volume":"8 ","pages":"Article 100069"},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773111124000123/pdfft?md5=3182e95c34352e02bfc5509f519f0127&pid=1-s2.0-S2773111124000123-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140638728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Copper nanoparticles from chemical, physical, and green synthesis to medicinal application: A review","authors":"Mehrab Pourmadadi , Roghaieh Holghoomi , Amin shamsabadipour , Reza Maleki-baladi , Abbas Rahdar , Sadanand Pandey","doi":"10.1016/j.plana.2024.100070","DOIUrl":"https://doi.org/10.1016/j.plana.2024.100070","url":null,"abstract":"<div><p>This article examines the viability of utilizing plant biomolecules in the environmentally sustainable synthesis of copper nanoparticles (Cu NPs). By harnessing their intrinsic capabilities of reduction and capping, plants present an environmentally friendly and economically viable substitute for conventional synthesis techniques. Through the manipulation of diverse parameters throughout the synthesis procedure, scientists are capable of attaining Cu NPs in the desired shapes and sizes, thereby customizing them to suit particular applications. This review centers on copper owing to its cost-effectiveness in comparison to other frequently utilized metals such as gold and silver. It explores the mechanisms that govern the environmentally friendly synthesis of Cu NPs. We conduct an exhaustive analysis of their wide-ranging medical and healthcare applications, emphasizing their capacity to fundamentally transform numerous treatment approaches. Furthermore, the review offers valuable perspectives on alternative synthesis techniques, facilitating a comparative evaluation and enabling well-informed choices to be made regarding particular applications. Through the integration of knowledge regarding environmentally friendly synthesis methods, a wide range of practical implementations, and economic factors, the objective of this review is to furnish a valuable asset to scientists, researchers, and healthcare practitioners who are investigating the capacity of Cu NPs to propel medical progress.</p></div>","PeriodicalId":101029,"journal":{"name":"Plant Nano Biology","volume":"8 ","pages":"Article 100070"},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2773111124000135/pdfft?md5=e7d872b6b70e02e26144d67586f37171&pid=1-s2.0-S2773111124000135-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140638725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}