New Crops最新文献

{"title":"Lighting-up Wars: Stories of Ca2+ Signaling in Plant Immunity","authors":"Zilu Zhang ,&nbsp;Qi Wang ,&nbsp;Haiqiao Yan ,&nbsp;Xiaoyan Cang ,&nbsp;Wei Li ,&nbsp;Jinyu He ,&nbsp;Meixiang Zhang ,&nbsp;Laiqing Lou ,&nbsp;Ran Wang ,&nbsp;Ming Chang","doi":"10.1016/j.ncrops.2024.100027","DOIUrl":"10.1016/j.ncrops.2024.100027","url":null,"abstract":"<div><p>Calcium ions (Ca²⁺) serve as key messengers in plant immune reactions. A typical Ca²⁺ signaling involves three steps: encoding specific Ca²⁺ signatures by Ca²⁺-permeable channels, decoding Ca²⁺ signals by Ca²⁺ sensors, and downstream responses. This review focuses on plasma membrane-localized Ca²⁺-permeable channels and cytosolic Ca²⁺ sensors, unraveling their roles in cytosolic Ca²⁺ influx and immune signaling during pattern-triggered immunity, effector-triggered immunity, and autoimmunity. Several unresolved questions were highlighted, including the regulation of Ca²⁺-permeable channel activity for immune induction and the mechanism behind Ca²⁺ influx-triggered hypersensitive response cell death. This concise overview provides insights into the complex interplay of Ca²⁺ signaling in plant immunity, paving the way for future investigations on molecular plant-microbe interactions.</p></div>","PeriodicalId":100953,"journal":{"name":"New Crops","volume":"1 ","pages":"Article 100027"},"PeriodicalIF":0.0,"publicationDate":"2024-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949952624000177/pdfft?md5=9db07903da1969d0331b5713a86b749e&pid=1-s2.0-S2949952624000177-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141139432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the frontier of plant phase separation: Current insights and future prospects","authors":"Panting Fan ,&nbsp;Jingjing Zhang ,&nbsp;Lefei Gao ,&nbsp;Mingke Wang ,&nbsp;Hui Kong ,&nbsp;Shengbo He","doi":"10.1016/j.ncrops.2024.100026","DOIUrl":"10.1016/j.ncrops.2024.100026","url":null,"abstract":"<div><p>In the rapidly evolving field of biology, phase separation has recently emerged as a revolutionary perspective, shedding new light on our comprehension of cellular processes. This review provides a comprehensive overview of current knowledge regarding phase separation in plants and charts promising avenues for future exploration. We delve into the fundamental principles of plant phase separation, highlighting the roles played by intrinsically disordered regions and prion-like domains. Summarizing significant advancements, we explore the involvement of phase separation in plant responses to environmental cues, as well as its involvement in growth and developmental processes, and plant-microbe interactions. Additionally, we present a streamlined workflow designed to guide the scientific community in conducting phase separation studies in plants. Lastly, we delineate lingering questions and propose potential applications of phase separation in agriculture.</p></div>","PeriodicalId":100953,"journal":{"name":"New Crops","volume":"1 ","pages":"Article 100026"},"PeriodicalIF":0.0,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949952624000165/pdfft?md5=450d688aecc55835440c2b0c311ad113&pid=1-s2.0-S2949952624000165-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141031369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Applications for single-cell and spatial transcriptomics in plant research","authors":"Qing Sang,&nbsp;Fanjiang Kong","doi":"10.1016/j.ncrops.2024.100025","DOIUrl":"10.1016/j.ncrops.2024.100025","url":null,"abstract":"<div><p>Cells of multicellular plants possess inherent heterogeneity. Recent progress in single-cell RNA sequencing (scRNA-seq) allows researchers to classify, characterize, and distinguish individual cells at the transcriptome level, enabling the identification of rare cell populations with functional importance. However, scRNA-seq obscures spatial information about cells. Spatial transcriptomics approaches have substantially improved our capacity to detect the spatial distribution of RNA transcripts throughout tissues, yet it remains challenging to characterize whole-transcriptome-level data for single cells spatially. In this review, we offer a concise overview of the scRNA-seq and spatial transcriptomics experimental and computational procedures and the computational strategies required to integrate scRNA-seq data with spatial transcriptomics. We demonstrate their impact on plant fundamental cell biology, discuss their advantages and current challenges, and provide an outlook on the future.</p></div>","PeriodicalId":100953,"journal":{"name":"New Crops","volume":"1 ","pages":"Article 100025"},"PeriodicalIF":0.0,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949952624000153/pdfft?md5=53f6d08fd117f9362e2da0bb22be2885&pid=1-s2.0-S2949952624000153-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141031444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ZmHAK17 encodes a Na+-selective transporter that promotes maize seed germination under salt conditions","authors":"Limin Wang ,&nbsp;Yanyan Wang ,&nbsp;Pan Yin ,&nbsp;Caifu Jiang ,&nbsp;Ming Zhang","doi":"10.1016/j.ncrops.2024.100024","DOIUrl":"10.1016/j.ncrops.2024.100024","url":null,"abstract":"<div><p>Elevated sodium ion (Na⁺) in saline farmlands adversely affect crops, notably by inhibiting seed germination. Given the importance of High-Affinity K⁺ Transporter (HAK) family Na⁺ transporters in plant salt tolerance and ZmHAK4 role in maize salt tolerance, our study focuses on characterizing HAK transporters related to ZmHAK4 in maize’s salt stress response. We found that ZmHAK17 is vital for promoting seed germination under saline conditions. Expressed mainly in the germinating embryo’s radicle, <em>ZmHAK17</em>, encodes a Na⁺ transporter located in the plasma membrane. Increased <em>ZmHAK17</em> transcript levels under salt stress facilitate Na⁺ efflux from the radicle, preventing Na⁺ accumulation in the embryo and reducing salt stress effects on germination. Mutants lacking <em>ZmHAK17</em> exhibit salt-sensitive germination. This study highlights ZmHAK17 as a key transporter enhancing maize germination in saline conditions, deepening our understanding of HAK family Na⁺ transporters’ role in salt tolerance and offering a new target gene for salt-tolerant maize breeding.</p></div>","PeriodicalId":100953,"journal":{"name":"New Crops","volume":"1 ","pages":"Article 100024"},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949952624000141/pdfft?md5=34fee71255f81fe88034efc34f67d73b&pid=1-s2.0-S2949952624000141-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141035299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A necessary considering factor for crop resistance: Precise regulation and effective utilization of beneficial microorganisms","authors":"Chenxi Kou ,&nbsp;Feiyang Song ,&nbsp;Dandan Li,&nbsp;Hongyang Xu,&nbsp;Shuxin Zhang,&nbsp;Wei Yang,&nbsp;Wenchong Shi,&nbsp;Zheng Gao","doi":"10.1016/j.ncrops.2024.100023","DOIUrl":"10.1016/j.ncrops.2024.100023","url":null,"abstract":"<div><p>Under global climate change circumstances, there has been growing acknowledgment of the critical need to prevent and manage both biotic and abiotic stress in crops. Plants employ a variety of signaling molecules, such as jasmonic acid (JA), abscisic acid (ABA), and Ca²⁺, to endure stress. Additionally, they utilize reactive oxygen species (ROS) and detoxifiers while also harnessing the assistance of beneficial microorganisms, including <em>Bacillus, Pseudomonas</em>, <em>Streptomyces</em>, and others. These microorganisms play a pivotal role in aiding crops in stress management, albeit with certain limitations to their efficacy. This article offers a synthesis and discourse on how crops can selectively engage with beneficial microorganisms via their root systems, elucidating the contributions of these microorganisms to stress tolerance. Drawing upon current insights, we propose refined strategies for leveraging microorganisms to bolster crop stress resilience. By advancing our grasp of plant-microorganism interactions and judiciously selecting and employing beneficial microorganisms, we aim to enhance the dependability and efficacy of microbial products in enhancing crop stress tolerance. This knowledge ultimately equips agricultural practitioners with the information needed to make informed decisions and bolster crops in adapting to rapidly changing environmental conditions.</p></div>","PeriodicalId":100953,"journal":{"name":"New Crops","volume":"1 ","pages":"Article 100023"},"PeriodicalIF":0.0,"publicationDate":"2024-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S294995262400013X/pdfft?md5=95ff58f5f3db7604854c0bcc82271cde&pid=1-s2.0-S294995262400013X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140783161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Plant cell walls: Emerging targets of stomata engineering to improve photosynthesis and water use efficiency","authors":"Yueyuan Wang,&nbsp;Pan Li,&nbsp;Wan Sun,&nbsp;Tian Zhang","doi":"10.1016/j.ncrops.2024.100021","DOIUrl":"10.1016/j.ncrops.2024.100021","url":null,"abstract":"<div><p>Stomata are tiny pores on leaf surfaces essential for plant transpiration and photosynthesis. As gatekeepers that mediate gas exchange between plants and the atmosphere, stomata exert a major influence on global carbon and water cycles. The shape and function of stomata are physically constrained by stomatal walls. Compared to the extensively studied genetic mechanisms of stomatal development and guard cell signaling, recent progress is only beginning to uncover the role of plant cell walls in stomatal development and dynamics. In this review, we summarize the research on cell walls of the kidney-shaped stomata from dicots and the dumbbell-shaped stomata from grasses. As the dynamic response of grass stomata is closely linked to its anatomical features that are limited by cell walls, we discuss the potential of plant cell walls as crucial targets for crop engineering to enhance carbon assimilation and water use efficiency.</p></div>","PeriodicalId":100953,"journal":{"name":"New Crops","volume":"1 ","pages":"Article 100021"},"PeriodicalIF":0.0,"publicationDate":"2024-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949952624000116/pdfft?md5=3e214ffd4d9c15f7f0c94d71378886e7&pid=1-s2.0-S2949952624000116-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140404104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural insights into ligand recognition and receptor activation of plant leucine-rich repeat (LRR) transmembrane receptors","authors":"Xiaobin Wei,&nbsp;Xinyi Liu,&nbsp;Xin Zhang,&nbsp;Shuangyu Guo,&nbsp;Jiaqing Shi","doi":"10.1016/j.ncrops.2024.100022","DOIUrl":"10.1016/j.ncrops.2024.100022","url":null,"abstract":"<div><p>Higher plants must coordinate their own growth and development by responding to a myriad of internal signals. Simultaneously, confronted with external signals such as pathogen invasion, drought and so on, they must constantly adjust themselves to adapt. These signals can be specifically recognized by transmembrane receptors on the cytoplasmic membrane, comprising receptor kinases (RKs) and receptor-like proteins (RLPs). Among these, leucine-rich repeat receptor kinases (LRR-RKs) and leucine-rich repeat receptor-like proteins (LRR-RLPs) form the largest category. By using X-ray crystallography and cryo-electron microscopy (cryo-EM) single-particle analysis, the ligand recognition and receptor activation mechanisms of some LRR-RKs/RLPs have been elucidated at the atomic scale. This deepens our understanding of the roles played by LRR-RKs/RLPs in the plant growth, development, responses to pathogen invasion and other environmental stresses. Moreover, it provides clues for precise genetic improvement aimed at improving yield, quality and stress resistance in economic crops. This review summarizes the recent progress in structural research on LRR-RKs/RLPs concerning plant growth, development, immune responses and other environmental stress responses. Additionally, this paper discusses how these receptors recognize their respective ligands and how ligand recognition triggers receptor activation from a structural biology perspective, offering new insights for crop improvement.</p></div>","PeriodicalId":100953,"journal":{"name":"New Crops","volume":"1 ","pages":"Article 100022"},"PeriodicalIF":0.0,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949952624000128/pdfft?md5=f12cddb157de951e0d3412f72851ffe4&pid=1-s2.0-S2949952624000128-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140404068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of natural and artificial selection on the yield differences among progeny derived from crossing between subspecies in cultivated rice","authors":"Na Xu ,&nbsp;Zhiwen Yu ,&nbsp;Xiaoche Wang ,&nbsp;Jiahao Lu ,&nbsp;Hao Chen ,&nbsp;Qi Sun ,&nbsp;Cheng Fei ,&nbsp;Xin Cui ,&nbsp;Zhengjin Xu ,&nbsp;Quan Xu","doi":"10.1016/j.ncrops.2024.100020","DOIUrl":"10.1016/j.ncrops.2024.100020","url":null,"abstract":"<div><p>Extended natural and artificial selection have introduced pronounced differences throughout the genomes, morphological traits, and geographical distributions of the two predominant rice strains, <em>Oryza sativa Xian</em>/<em>indica</em> (XI) and <em>O. sativa Geng</em>/<em>japonica</em> (GJ). However, the unique roles of natural and artificial selection in strain differentiation remain uncharacterized. Therefore, we independently produced advanced inbreeding populations in typical GJ- and XI-cultivated areas, beginning from the F₂ generation. We utilized pedigree and bulk-selective methods to characterize artificial and natural selection, respectively. Our examination uncovered preferences between artificial and natural selection. Artificial selection was favored by individuals with increased grain count per panicle but reduced panicle number, while natural selection favored traits like greater panicle number, reduced grains per panicle, and higher thousand-grain weight, especially in the XI cultivation areas. Notably, in the XI regions, natural selection produced a preference for wider grains, indicating that the elongated grains in XI rice may be caused by artificial rather than natural selection. Using <em>de novo</em> assembly of a high-quality parental genome, we observed an increased prevalence of the GJ genotype in GJ areas compared to XI areas, segregation distortion in the advanced inbreeding population could be attributed to loci regulating hybrid sterility. Notably, the semi-dwarf allele <em>sd1-d</em>, linked to the “Green Revolution”, was not favored in either selection paradigm in northern areas, possibly due to its disadvantages on grain yield per plant and NH₄⁺ uptake rate. Our study offers novel perspectives into the contributions of natural and artificial selection to the divergence between XI and GJ subspecies.</p></div>","PeriodicalId":100953,"journal":{"name":"New Crops","volume":"1 ","pages":"Article 100020"},"PeriodicalIF":0.0,"publicationDate":"2024-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949952624000104/pdfft?md5=69ceab0b52ac646f53faffc5973f202a&pid=1-s2.0-S2949952624000104-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140282961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk assessment of RNAi-based biopesticides","authors":"Xuming Luo ,&nbsp;Satyabrata Nanda ,&nbsp;Youjun Zhang ,&nbsp;Xuguo Zhou ,&nbsp;Chunxiao Yang ,&nbsp;Huipeng Pan","doi":"10.1016/j.ncrops.2024.100019","DOIUrl":"10.1016/j.ncrops.2024.100019","url":null,"abstract":"<div><p>RNA interference (RNAi) is an efficient molecular approach in which double-stranded RNA (dsRNA) can effectively knock down the expression of certain genes, promoting mRNA degradation, and gene function loss. Based on the principle of RNAi, a novel and eco-friendly biopesticide has been characterized and used in recent years. RNAi-based biopesticides have high specificity, efficiency, and easy degradation, which have ushered in the third revolution in the history of pesticides. Additionally, these properties of RNAi-based biopesticides are of great significance in achieving sustainable agricultural development. However, before the market release of any biopesticides, it is essential to consider whether they will adversely affect human health and the environment. This paper reviews RNAi-based biopesticides' different modes of action and the diverse associated risks, such as environmental risk (environmental fate, off-target effects, exposure assessment, and resistance development), human health risk, and government policies.</p></div>","PeriodicalId":100953,"journal":{"name":"New Crops","volume":"1 ","pages":"Article 100019"},"PeriodicalIF":0.0,"publicationDate":"2024-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949952624000098/pdfft?md5=f162b96dc728171b2710fdacfc16ead9&pid=1-s2.0-S2949952624000098-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140282351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation and genetic dissection of the powdery mildew resistance in 558 wheat accessions","authors":"Yuli Jin ,&nbsp;Guohao Han ,&nbsp;Wenjing Zhang ,&nbsp;Bin Bu ,&nbsp;Ya Zhao ,&nbsp;Jiaojiao Wang ,&nbsp;Ruishan Liu ,&nbsp;Hong Yang ,&nbsp;Hongxing Xu ,&nbsp;Pengtao Ma","doi":"10.1016/j.ncrops.2024.100018","DOIUrl":"10.1016/j.ncrops.2024.100018","url":null,"abstract":"<div><p>Powdery mildew, a widespread and destructive wheat disease caused by the fungal pathogen <em>Blumeria graminis</em> f. sp. <em>tritici</em> (<em>Bgt</em>), results in significant yield losses globally. Employing host resistance is the most cost-effective and environmentally sustainable approach to managing this disease. Assessing the resistance levels of wheat germplasms and understanding the genetic underpinnings of this resistance is crucial. In this study, we evaluated the seedling resistance to powdery mildew in 558 wheat accessions, along with the presence of resistance genes <em>Pm1</em>, <em>Pm2</em>, <em>Pm4</em>, <em>Pm5</em>, <em>Pm6</em>, <em>Pm8</em>, <em>Pm12</em>, <em>Pm21</em>, <em>Pm24</em>, <em>Pm41</em>, <em>Pm42</em>, <em>Pm45</em>, <em>Pm47</em>, <em>Pm60</em>, and <em>Pm69</em> using various <em>Bgt</em> isolates and associated diagnostic markers. The study revealed that out of 558 wheat accessions tested, only 25 showed resistance to the <em>Bgt</em> isolate E09, highlighting a general lack of powdery mildew resistance among the evaluated accessions. Furthermore, these 25 accessions exhibited a significantly different resistance spectrum to 25 additional <em>Bgt</em> isolates. Notably, seven of these accessions were resistant to all the tested isolates, indicating they possess <em>Pm</em> genes with broad-spectrum resistance. Molecular analysis using closely linked or diagnostic markers revealed diverse resistance gene profiles: 249 accessions harbored a single tested <em>Pm</em> gene, 75 accessions possessed combinations of <em>Pm</em> genes, and 234 accessions lacked any of the tested genes. <em>Pm8</em> was the most frequently detected gene, present in 27.42% of accessions, whereas <em>Pm5</em>, <em>Pm12</em>, <em>Pm24</em>, <em>Pm41</em>, <em>Pm42</em>, <em>Pm45</em>, <em>Pm47</em> and <em>Pm69</em> were not detected. Among the seven accessions resistant to all 26 tested isolates, <em>Pm21</em> was detected in four accessions (HengS29, Chang 4640, Xinong 556, and ML728). <em>Pm2</em> and <em>Pm60</em> were identified in Emai 18 and Xinmai 296, respectively. Interestingly, none of the tested genes were detected in Emai 16, suggesting the presence of potentially novel <em>Pm</em> gene(s) conferring broad-spectrum resistance. These findings offer valuable insights for the strategic dissemination of these resistant accessions and for targeted breeding programs aimed at combating powdery mildew.</p></div>","PeriodicalId":100953,"journal":{"name":"New Crops","volume":"1 ","pages":"Article 100018"},"PeriodicalIF":0.0,"publicationDate":"2024-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2949952624000086/pdfft?md5=1fd2e9deb53ea4e9eb70887448631030&pid=1-s2.0-S2949952624000086-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140083030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}