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Glutamatergic metabolites and resting-state connectivity in psychosis risk: a combined multi-voxel MRS and fMRI study 精神疾病风险中的谷氨酸代谢物和静息状态连通性：一项多体素MRS和fMRI联合研究
Neuroscience Applied Pub Date : 2026-01-01 Epub Date: 2026-05-20 DOI: 10.1016/j.nsa.2026.106958
A. Gee , A. Kiemes , S.R. Knight , N.R. Livingston , P.B. Lukow , D.J. Lythgoe , B. Haege , N. Vorontsova , J. Donocik , J. Davies , E.A. Rabiner , M.B. Wall , T.J. Spencer , A. De Micheli , P. Fusar-Poli , A.A. Grace , S.C. Williams , P. McGuire , P. Dazzan , G. Modinos
{"title":"Glutamatergic metabolites and resting-state connectivity in psychosis risk: a combined multi-voxel MRS and fMRI study","authors":"A. Gee , A. Kiemes , S.R. Knight , N.R. Livingston , P.B. Lukow , D.J. Lythgoe , B. Haege , N. Vorontsova , J. Donocik , J. Davies , E.A. Rabiner , M.B. Wall , T.J. Spencer , A. De Micheli , P. Fusar-Poli , A.A. Grace , S.C. Williams , P. McGuire , P. Dazzan , G. Modinos","doi":"10.1016/j.nsa.2026.106958","DOIUrl":"10.1016/j.nsa.2026.106958","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"5 ","pages":"Article 106958"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147991128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inhibitory control event-related fields as predictive biomarkers for binge drinking in adolescents 抑制控制事件相关领域作为青少年酗酒的预测性生物标志物
Neuroscience Applied Pub Date : 2026-01-01 Epub Date: 2026-05-20 DOI: 10.1016/j.nsa.2026.106962
L. Lopez Abad , D. Shpakivska Bilan , A. Del Cerro León , M. Uceta , L. Antón Toro , R. Bruña , L.M. García Moreno , F. Maestú
{"title":"Inhibitory control event-related fields as predictive biomarkers for binge drinking in adolescents","authors":"L. Lopez Abad , D. Shpakivska Bilan , A. Del Cerro León , M. Uceta , L. Antón Toro , R. Bruña , L.M. García Moreno , F. Maestú","doi":"10.1016/j.nsa.2026.106962","DOIUrl":"10.1016/j.nsa.2026.106962","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"5 ","pages":"Article 106962"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147991131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microglial pathology in response to IL-6 is driven by cis, rather than trans, signalling 响应IL-6的小胶质细胞病理是由顺式而非反式信号驱动的
Neuroscience Applied Pub Date : 2026-01-01 Epub Date: 2026-05-20 DOI: 10.1016/j.nsa.2026.106974
A. Brown , A.I. Baloc , C. De Brito E Raimundo , K. Long , A. Vernon
{"title":"Microglial pathology in response to IL-6 is driven by cis, rather than trans, signalling","authors":"A. Brown , A.I. Baloc , C. De Brito E Raimundo , K. Long , A. Vernon","doi":"10.1016/j.nsa.2026.106974","DOIUrl":"10.1016/j.nsa.2026.106974","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"5 ","pages":"Article 106974"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147991142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Default mode network dynamics and early social dysfunction in transgenic Alzheimer’s mice 转基因阿尔茨海默氏症小鼠的默认模式网络动力学和早期社会功能障碍
Neuroscience Applied Pub Date : 2026-01-01 Epub Date: 2026-05-20 DOI: 10.1016/j.nsa.2026.106896
M. Ronde , E.A. Van der Zee , M.J.H. Kas
{"title":"Default mode network dynamics and early social dysfunction in transgenic Alzheimer’s mice","authors":"M. Ronde , E.A. Van der Zee , M.J.H. Kas","doi":"10.1016/j.nsa.2026.106896","DOIUrl":"10.1016/j.nsa.2026.106896","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"5 ","pages":"Article 106896"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147991348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Symptom-level antidepressant response to psilocybin: exploratory outcomes comparing psilocybin treatment to niacin 对裸盖菇素的症状水平抗抑郁反应：比较裸盖菇素治疗与烟酸治疗的探索性结果
Neuroscience Applied Pub Date : 2026-01-01 Epub Date: 2026-05-20 DOI: 10.1016/j.nsa.2026.106904
E. Lopez , J. Lundberg , F. Hieronymus , M. Beckman , H. Yngwe , C.J. Ekman , M. Tiger , N. Edvall
{"title":"Symptom-level antidepressant response to psilocybin: exploratory outcomes comparing psilocybin treatment to niacin","authors":"E. Lopez , J. Lundberg , F. Hieronymus , M. Beckman , H. Yngwe , C.J. Ekman , M. Tiger , N. Edvall","doi":"10.1016/j.nsa.2026.106904","DOIUrl":"10.1016/j.nsa.2026.106904","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"5 ","pages":"Article 106904"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147991495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting disease trajectories in the nesda cohort through a network-based assessment of plasticity 通过基于网络的可塑性评估来预测nesda队列中的疾病轨迹
Neuroscience Applied Pub Date : 2026-01-01 Epub Date: 2026-05-20 DOI: 10.1016/j.nsa.2026.106919
G. Petruccioli , C. Delli Colli , A. Viglione , S. Poggini , B.W. Penninx , I. Branchi
{"title":"Predicting disease trajectories in the nesda cohort through a network-based assessment of plasticity","authors":"G. Petruccioli , C. Delli Colli , A. Viglione , S. Poggini , B.W. Penninx , I. Branchi","doi":"10.1016/j.nsa.2026.106919","DOIUrl":"10.1016/j.nsa.2026.106919","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"5 ","pages":"Article 106919"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147991498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estradiol administration modulates apparent brain aging 雌二醇可以调节明显的脑老化
Neuroscience Applied Pub Date : 2026-01-01 Epub Date: 2026-05-20 DOI: 10.1016/j.nsa.2026.106920
A. Denninger , T. Kaufmann , B. Derntl , L. Kogler
{"title":"Estradiol administration modulates apparent brain aging","authors":"A. Denninger , T. Kaufmann , B. Derntl , L. Kogler","doi":"10.1016/j.nsa.2026.106920","DOIUrl":"10.1016/j.nsa.2026.106920","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"5 ","pages":"Article 106920"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147991499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing psychotherapy patients’ social context through personal networks and experience sampling: A mixed methods case series exploring feasibility 通过个人网络和经验抽样来评估心理治疗患者的社会环境：一个探索可行性的混合方法案例系列
IF 3
Neuroscience Applied Pub Date : 2026-01-01 Epub Date: 2026-09-09 DOI: 10.1016/j.nsa.2026.107029
Marie Stadel, Janneke van Houts, Shanice Wortel, Barbara Montagne, Laura F. Bringmann
{"title":"Assessing psychotherapy patients’ social context through personal networks and experience sampling: A mixed methods case series exploring feasibility","authors":"Marie Stadel,&nbsp;Janneke van Houts,&nbsp;Shanice Wortel,&nbsp;Barbara Montagne,&nbsp;Laura F. Bringmann","doi":"10.1016/j.nsa.2026.107029","DOIUrl":"10.1016/j.nsa.2026.107029","url":null,"abstract":"<div><div>This study explored the feasibility and perceived clinical utility of a novel psychotherapy intervention consisting of two components (1) assessment of patients' social context using the experience sampling methodology (ESM) and personal social network data collection (PSN) and (2) a feedback report summarizing the collected data. Four qualitatively driven concurrent embedded mixed-methods case studies were conducted in a large mental health care facility in the Netherlands and included nine young adults receiving either individual or group psychotherapy: six in part-time treatment and three transitioning from inpatient to outpatient care. Feasibility and utility were evaluated using codebook thematic analysis of semi-structured patient and therapist interviews, patient compliance with the intervention components and researchers' reflexive field notes. Overall, the intervention appeared most feasible in individual therapy, in which patient and therapist engaged with it collaboratively. Engagement was more difficult among avoidant patients and when the intervention was experienced as <em>too confronting</em> by patients, highlighting the importance of establishing rapport before its use. The intervention yielded varying degrees of insight for patients, depending on their ability to engage with the assessments and feedback-based therapeutic dialogue. The feedback report specifically improved therapists' understanding of patients’ social context. Future implementation will require automation, integration into digital clinical infrastructure, and therapist training to support appropriate interpretation of feedback and follow-up action.</div></div>","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"5 ","pages":"Article 107029"},"PeriodicalIF":3.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148951109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proteomic correlates of suicidality in depression 抑郁症中自杀行为的蛋白质组学相关性
Neuroscience Applied Pub Date : 2026-01-01 Epub Date: 2026-01-02 DOI: 10.1016/j.nsa.2025.105579
C. Schiweck , C. Werning , J. Steinheimer , M. Aichholzer , C. Uckermark , A. Bouzouina , S. Schillo , J. Freiling , F. Erhardt , A. Balliet , H. Reinken , A. Reif , S. Edwin Thanarajah
{"title":"Proteomic correlates of suicidality in depression","authors":"C. Schiweck ,&nbsp;C. Werning ,&nbsp;J. Steinheimer ,&nbsp;M. Aichholzer ,&nbsp;C. Uckermark ,&nbsp;A. Bouzouina ,&nbsp;S. Schillo ,&nbsp;J. Freiling ,&nbsp;F. Erhardt ,&nbsp;A. Balliet ,&nbsp;H. Reinken ,&nbsp;A. Reif ,&nbsp;S. Edwin Thanarajah","doi":"10.1016/j.nsa.2025.105579","DOIUrl":"10.1016/j.nsa.2025.105579","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"5 ","pages":"Article 105579"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145868636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the effects of deuterium depletion on the development and function of neurons 研究缺氘对神经元发育和功能的影响
Neuroscience Applied Pub Date : 2026-01-01 Epub Date: 2026-01-02 DOI: 10.1016/j.nsa.2025.105594
D. Tsounis , D. Anthony , A.M. Pineau , C. Hamann , R. Riemens , D. van den Hove , K.P. Lesch
{"title":"Investigating the effects of deuterium depletion on the development and function of neurons","authors":"D. Tsounis ,&nbsp;D. Anthony ,&nbsp;A.M. Pineau ,&nbsp;C. Hamann ,&nbsp;R. Riemens ,&nbsp;D. van den Hove ,&nbsp;K.P. Lesch","doi":"10.1016/j.nsa.2025.105594","DOIUrl":"10.1016/j.nsa.2025.105594","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"5 ","pages":"Article 105594"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145868866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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