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Capturing the continuum in biopsychosocial research: Measurement challenges within transdiagnostic and dimensional approaches to mental disorders
Neuroscience Applied Pub Date : 2025-01-01 DOI: 10.1016/j.nsa.2025.105508
Anna Schulze , Stefanie Lis
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引用次数: 0
Tryptophan-metabolizing gut microbes are associated with anxiolytic and neurogenic effects of voluntary exercise in rats
Neuroscience Applied Pub Date : 2025-01-01 DOI: 10.1016/j.nsa.2025.105462
M.G. Caruso , S. Nicolas , F. Donoso , E. Gunnigle , J.F. Cryan , O.F. O'Leary , Y.M. Nolan
{"title":"Tryptophan-metabolizing gut microbes are associated with anxiolytic and neurogenic effects of voluntary exercise in rats","authors":"M.G. Caruso , S. Nicolas , F. Donoso , E. Gunnigle , J.F. Cryan , O.F. O'Leary , Y.M. Nolan","doi":"10.1016/j.nsa.2025.105462","DOIUrl":"10.1016/j.nsa.2025.105462","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"4 ","pages":"Article 105462"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143637102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuromodulation in Epilepsy through Temporal Interference Stimulation in Human whole-brain models
Neuroscience Applied Pub Date : 2025-01-01 DOI: 10.1016/j.nsa.2025.105505
C. Duprat , J.P. Triebkorn , B. Dollomaja , D. Depannemaecker , H. Wang , V. Jirsa
{"title":"Neuromodulation in Epilepsy through Temporal Interference Stimulation in Human whole-brain models","authors":"C. Duprat , J.P. Triebkorn , B. Dollomaja , D. Depannemaecker , H. Wang , V. Jirsa","doi":"10.1016/j.nsa.2025.105505","DOIUrl":"10.1016/j.nsa.2025.105505","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"4 ","pages":"Article 105505"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143637109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Striatal overexpression of glial cell line-derived neurotrophic factor elicits changes in cerebral energy metabolism
Neuroscience Applied Pub Date : 2025-01-01 DOI: 10.1016/j.nsa.2025.105439
P. Kupper , M. Kanarik , K. Liiver , M. Airavaara , R. Shimmo , M. Saarma , J. Harro
{"title":"Striatal overexpression of glial cell line-derived neurotrophic factor elicits changes in cerebral energy metabolism","authors":"P. Kupper , M. Kanarik , K. Liiver , M. Airavaara , R. Shimmo , M. Saarma , J. Harro","doi":"10.1016/j.nsa.2025.105439","DOIUrl":"10.1016/j.nsa.2025.105439","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"4 ","pages":"Article 105439"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143637210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Agmatine stimulates serotonergic neurons of the dorsal raphe nucleus via a mechanism involving serotonin-1A/2A receptors
Neuroscience Applied Pub Date : 2025-01-01 DOI: 10.1016/j.nsa.2025.105493
H. Özbaşak , R. Paliokha , R. Dekhtiarenko , D. Grinchii , E. Dremencov
{"title":"Agmatine stimulates serotonergic neurons of the dorsal raphe nucleus via a mechanism involving serotonin-1A/2A receptors","authors":"H. Özbaşak , R. Paliokha , R. Dekhtiarenko , D. Grinchii , E. Dremencov","doi":"10.1016/j.nsa.2025.105493","DOIUrl":"10.1016/j.nsa.2025.105493","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"4 ","pages":"Article 105493"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143636480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repurposing of SYK inhibitor fostamatinib in a diet-induced in vivo model of insulin resistance and neuroinflammation
Neuroscience Applied Pub Date : 2025-01-01 DOI: 10.1016/j.nsa.2025.105490
E. Aimaretti , E. Porchietto , G. Ferreira Alves , G. Einaudi , C. Rubeo , E. Marzani , R. Mastrocola , C. Cifani , M. Aragno , M. Collino
{"title":"Repurposing of SYK inhibitor fostamatinib in a diet-induced in vivo model of insulin resistance and neuroinflammation","authors":"E. Aimaretti , E. Porchietto , G. Ferreira Alves , G. Einaudi , C. Rubeo , E. Marzani , R. Mastrocola , C. Cifani , M. Aragno , M. Collino","doi":"10.1016/j.nsa.2025.105490","DOIUrl":"10.1016/j.nsa.2025.105490","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"4 ","pages":"Article 105490"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143636665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Mknk-Syngap1 Axis in Specific Learning Disorder: Epigenetic Regulations and New Perspectives
Neuroscience Applied Pub Date : 2025-01-01 DOI: 10.1016/j.nsa.2025.105485
C. Mercan Işık , E.B. Tüzemen Bayyurt , N. Özbilum Şahin
{"title":"The Mknk-Syngap1 Axis in Specific Learning Disorder: Epigenetic Regulations and New Perspectives","authors":"C. Mercan Işık , E.B. Tüzemen Bayyurt , N. Özbilum Şahin","doi":"10.1016/j.nsa.2025.105485","DOIUrl":"10.1016/j.nsa.2025.105485","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"4 ","pages":"Article 105485"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143636796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential of physical activity on youth's mental health: a review of umbrella reviews 体育活动对青少年心理健康的潜在影响：伞状评论综述
Neuroscience Applied Pub Date : 2025-01-01 DOI: 10.1016/j.nsa.2025.105459
C. Ciacchella , B. Collacchi , I. Branchi , F. Cirulli
{"title":"Potential of physical activity on youth's mental health: a review of umbrella reviews","authors":"C. Ciacchella , B. Collacchi , I. Branchi , F. Cirulli","doi":"10.1016/j.nsa.2025.105459","DOIUrl":"10.1016/j.nsa.2025.105459","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"4 ","pages":"Article 105459"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143637099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual ligands modeled from oleoylethanolamide: a novel approach for the treatment of binge eating behavior 油酰乙醇酰胺双配体模型：治疗暴食行为的新方法
Neuroscience Applied Pub Date : 2025-01-01 DOI: 10.1016/j.nsa.2025.105445
M.F. De Ceglia , L. Botticelli , E. Micioni Di Bonaventura , A. Vargas Fuentes , M.V. Micioni Di Bonaventura , C. Cifani , F. Rodriguez de Fonseca
{"title":"Dual ligands modeled from oleoylethanolamide: a novel approach for the treatment of binge eating behavior","authors":"M.F. De Ceglia , L. Botticelli , E. Micioni Di Bonaventura , A. Vargas Fuentes , M.V. Micioni Di Bonaventura , C. Cifani , F. Rodriguez de Fonseca","doi":"10.1016/j.nsa.2025.105445","DOIUrl":"10.1016/j.nsa.2025.105445","url":null,"abstract":"","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"4 ","pages":"Article 105445"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143636233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An investigation of acute physiological and psychological moderators of psychedelic-induced personality change among healthy volunteers
Neuroscience Applied Pub Date : 2025-01-01 DOI: 10.1016/j.nsa.2024.104092
Kate Godfrey , Brandon Weiss , Xinhu Zhang , Meg Spriggs , Joseph Peill , Taylor Lyons , Robin Carhart-Harris , David Erritzoe
{"title":"An investigation of acute physiological and psychological moderators of psychedelic-induced personality change among healthy volunteers","authors":"Kate Godfrey ,&nbsp;Brandon Weiss ,&nbsp;Xinhu Zhang ,&nbsp;Meg Spriggs ,&nbsp;Joseph Peill ,&nbsp;Taylor Lyons ,&nbsp;Robin Carhart-Harris ,&nbsp;David Erritzoe","doi":"10.1016/j.nsa.2024.104092","DOIUrl":"10.1016/j.nsa.2024.104092","url":null,"abstract":"<div><div>This study investigated the effects of a single high-dose of psilocybin on personality traits in psychedelic-naïve healthy volunteers. These data originate from a larger within-subjects fixed-order design trial, where a single high dose of psilocybin (25 mg) was administered in a psychologically supportive setting and was compared against a (one-month) prior, 1 mg ‘placebo’ dose. Personality shifts were assessed by the Big Five Inventory and the Big Five Aspect Scale, while the Altered States of Consciousness questionnaire (5D-ASC) and the Psychological Insight Scale gauged the acute psychological effects of the substance. Electroencephalography provided neurophysiological insights, specifically examining alpha power and Lempel-Ziv complexity (LZc). Results indicated significant reductions in neuroticism one month after 25 mg psilocybin administration, a finding consistent with prior studies. Reductions in neuroticism were moderated by the subjective meaningfulness of the psychedelic experience, as well as by the dread of ego dissolution subscale of the 5D-ASC, suggesting a relationship between acute drug effects and enduring personality alterations. Thus, this study substantiates the role of acute psychedelic states in catalysing lasting personality transformations in a generally beneficial direction, with broader implications for therapeutic applications and understanding of personality dynamics.</div></div>","PeriodicalId":100952,"journal":{"name":"Neuroscience Applied","volume":"4 ","pages":"Article 104092"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143162433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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