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Advances in clinical application of nanoparticle-based therapy for cancer treatment: A systematic review 基于纳米粒子的癌症治疗临床应用进展:系统综述
Nano TransMed Pub Date : 2024-04-24 DOI: 10.1016/j.ntm.2024.100036
Pingchuan Ma , Guanru Wang , Ke Men , Chunjie Li , Ning Gao , Longjiang Li
{"title":"Advances in clinical application of nanoparticle-based therapy for cancer treatment: A systematic review","authors":"Pingchuan Ma ,&nbsp;Guanru Wang ,&nbsp;Ke Men ,&nbsp;Chunjie Li ,&nbsp;Ning Gao ,&nbsp;Longjiang Li","doi":"10.1016/j.ntm.2024.100036","DOIUrl":"10.1016/j.ntm.2024.100036","url":null,"abstract":"<div><h3>Background</h3><p>Due to the rapid development of nanotechnology and nanocomplex synthetic techniques, a large number of nanoparticle-based cancer medicines have been evaluated or applied in clinical trials for utility. However, the quality, efficiency and adverse events of these trials are sometimes controversial. Our systematic review aimed to better summary the current nanoparticle-related randomized controlled trials for cancer treatment, assess their quality and analyze the outcomes reported.</p></div><div><h3>Methods</h3><p>A comprehensive search was performed in electronic database as follows: PubMed, Embase, the Cochrane Library and Web of Science, until February 2024. We then identified the randomized controlled trials (RCTs) that investigate the nanoparticle-based therapy versus placebo, ordinary chemotherapy, standard of care or different doses of nanoparticles in cancer patients. The information, primary outcomes and adverse events records of trials were extracted.</p></div><div><h3>Results</h3><p>31 RCTs were included, Inside, 22 studies used paclitaxel related nanoparticle in their RCTs, including 18 trials of nanoparticle albumin-bound (nab)-paclitaxel. A total of 10399 patients were enrolled for evaluation. Most of the included trials were ranked as excellent or good quality after assessed according to CONSORT checklist. The treatment efficiency reflected via progression-free survival (PFS), overall survival (OS), and pathological complete response (pCR) were not significantly superior to control arm. Lymphopenia, leucopenia and neutropenia were the most common complications in paclitaxel-related therapies.</p></div><div><h3>Conclusions</h3><p>According to current trials, the advantages of nanoparticles-based therapy were not significant compared to ordinary chemotherapy schedule no matter in efficiency or safety for cancer treatment. The majority of nanomedicine currently in evaluation is chemotherapy medicine related, lacking of the attempts of other treatment strategy. Thus, it is urgent to broaden the therapy strategy applied in nanoparticle utility for cancer treatment exploration.</p></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"3 ","pages":"Article 100036"},"PeriodicalIF":0.0,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2790676024000074/pdfft?md5=e5e8a78b1476c8509b52e958fe02378d&pid=1-s2.0-S2790676024000074-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140780432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound-triggerennd piezocatalytic conductive Guar gum/PEDOT: PSS/BTO composite hydrogels for bacterial-infected skin wound healing 用于细菌感染皮肤伤口愈合的超声触发压电导电瓜尔胶/PEDOT:用于细菌感染皮肤伤口愈合的 PSS/BTO 复合水凝胶
Nano TransMed Pub Date : 2024-04-14 DOI: 10.1016/j.ntm.2024.100035
Shuyan Zhang , Danna Chen , Zhipeng Gu , Hongrong Luo , Xianchun Chen , Qiang Fu
{"title":"Ultrasound-triggerennd piezocatalytic conductive Guar gum/PEDOT: PSS/BTO composite hydrogels for bacterial-infected skin wound healing","authors":"Shuyan Zhang ,&nbsp;Danna Chen ,&nbsp;Zhipeng Gu ,&nbsp;Hongrong Luo ,&nbsp;Xianchun Chen ,&nbsp;Qiang Fu","doi":"10.1016/j.ntm.2024.100035","DOIUrl":"https://doi.org/10.1016/j.ntm.2024.100035","url":null,"abstract":"<div><p>Open skin wounds are susceptible to infections by multidrug-resistant bacteria, which can lead to delayed wound healing or worsening of symptoms. Therefore, there is an urgent need to develop a comprehensive strategy that addresses bacterial infections while simultaneously promoting wound healing for optimal clinical outcomes. In this study, we aimed to combine the benefits of antibacterial piezoelectric catalysis action and controlled electrical stimulation to promote skin tissue repair. Initially, piezoelectric catalytic BaTiO<sub>3</sub>(BTO) nanoparticles were coated with polydopamine (PDA) to improve the interface compatibility between inorganic and organic phase. Subsequently, a novel conductive composite hydrogel termed PPGSCH was synthesized by doping PDA@BTO into poly (3, 4-ethylenedioxythiophene) -poly (styrene sulfonate) (PEDOT: PSS) hydrogel. Traditional dye degradation experiments and EPR tests found that PDA@BTO nanoparticles exhibited superior piezoelectric catalytic efficiency compared with the pristine BTO. Rheological tests and electrical conductivity tests demonstrated better electrical adaptability and mechanical stability of PPGSCH. Remarkably, under the synergism of piezoelectricity and electric polarization induced by ultrasound (US), the antibacterial rate of PPGSCH exceeded 90% <em>in vitro</em>. Furthermore, when subjected to 0.5 W/cm<sup>2</sup> US irradiation, it can generate moderate levels of reactive oxygen (ROS) and micro current, promoting the proliferation and migration of mouse fibroblasts. Animal experiments on infected skin wounds in mice showed that PPGSCH could reduce inflammation, accelerate angiogenesis, and ultimately expedite the infected wound healing. This work opens up new possibilities for enhancing the repair of infected skin wounds.</p></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"3 ","pages":"Article 100035"},"PeriodicalIF":0.0,"publicationDate":"2024-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2790676024000062/pdfft?md5=a8c081dc8edfd3a2752373135fd0bd26&pid=1-s2.0-S2790676024000062-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140651040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Photothermal/photodynamic antibacterial hydrogel embedded with copper carbon dots and Au nanoparticles 嵌入铜碳点和金纳米粒子的光热/光动力抗菌水凝胶
Nano TransMed Pub Date : 2024-02-23 DOI: 10.1016/j.ntm.2024.100034
Ju Lv, Yuheng Qiu, Lang Pan, Xinyue Zhang, Mengting Li, Xueqiong Yin
{"title":"Photothermal/photodynamic antibacterial hydrogel embedded with copper carbon dots and Au nanoparticles","authors":"Ju Lv,&nbsp;Yuheng Qiu,&nbsp;Lang Pan,&nbsp;Xinyue Zhang,&nbsp;Mengting Li,&nbsp;Xueqiong Yin","doi":"10.1016/j.ntm.2024.100034","DOIUrl":"https://doi.org/10.1016/j.ntm.2024.100034","url":null,"abstract":"<div><p>In this paper, we created a hydrogel (named AuNPs-CuCCDs@Gel) with photothermal and photodynamic performance through incorporating copper carbon dots (CuCCDs) and Au nanoparticles (AuNPs) into gelatin and chitosan hydrogels. The thus-obtained hydrogel exhibited a high photothermal and photodynamic antibacterial activity with a superior singlet oxygen yield (0.70), which was better than that of methylene blue (0.52). After laser irradiation at 808 nm for 6 min, the temperature of AuNPs-CuCCDs@Gel rose from room temperature to 50 °C, which manifested good effects for avoiding local heat damage and protecting normal cells. AuNPs-CuCCDs@Gel exhibited the highest antibacterial efficacy of 96.46% and 97.48% against <em>S. aureus</em> and <em>E. coli</em> respectively. The significantly improved bactericidal performance was attributed to the synergistic effects of hyperthermia and reactive oxygen species (ROS). This work suggests that photothermal/photodynamic antibacterial hydrogel is a promising agent for treating wound infection.</p></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"3 ","pages":"Article 100034"},"PeriodicalIF":0.0,"publicationDate":"2024-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2790676024000050/pdfft?md5=933d0638f51ac9ed7eaf1de040c39b9f&pid=1-s2.0-S2790676024000050-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140066914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum regarding previously published articles 关于以前发表的文章的勘误
Nano TransMed Pub Date : 2024-02-20 DOI: 10.1016/j.ntm.2024.100031
{"title":"Erratum regarding previously published articles","authors":"","doi":"10.1016/j.ntm.2024.100031","DOIUrl":"https://doi.org/10.1016/j.ntm.2024.100031","url":null,"abstract":"","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"3 ","pages":"Article 100031"},"PeriodicalIF":0.0,"publicationDate":"2024-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2790676024000025/pdfft?md5=4d11dd3b39030a65f878107ccb938dd7&pid=1-s2.0-S2790676024000025-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139907351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advances of calcium phosphate nanoceramics for the osteoinductive potential and mechanistic pathways in maxillofacial bone defect repair 磷酸钙纳米陶瓷在颌面骨缺损修复中的骨诱导潜力和机制途径研究进展
Nano TransMed Pub Date : 2024-02-04 DOI: 10.1016/j.ntm.2024.100033
Yifan Gou , Kailong Qi , Yige Wei , Zhipeng Gu , Huixu Xie
{"title":"Advances of calcium phosphate nanoceramics for the osteoinductive potential and mechanistic pathways in maxillofacial bone defect repair","authors":"Yifan Gou ,&nbsp;Kailong Qi ,&nbsp;Yige Wei ,&nbsp;Zhipeng Gu ,&nbsp;Huixu Xie","doi":"10.1016/j.ntm.2024.100033","DOIUrl":"https://doi.org/10.1016/j.ntm.2024.100033","url":null,"abstract":"<div><p>Maxillofacial bone defects, arising from congenital malformations, tumors, infections, and traumas, represent a common clinical condition that impairs patients' appearance, speech, and motor functions. Calcium phosphate nanoceramics, which bear a chemical composition similar to autologous bone, demonstrate strong biocompatibility and osteoconductivity, making them an extensively applied material in bone defect repairing. Notably, these nanoceramics exhibit inherent osteoinductive properties ,which can stimulate osteogenesis at non-osseous sites ,without the need for additional cells or growth factors, these aspects further expand their application in bone repair. Nevertheless, the precise osteoinductive mechanism of calcium phosphate nanoceramics remains elusive, and differences in vivo individual persist, thereby academic communities need to resolve the pressing issues that restrict their use. This paper reviews the advancements in research on the properties of calcium phosphate nanoceramics and the factors affecting the biological process of bone formation, aiming to provide new insights for the treatment of maxillofacial bone defects.</p></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"3 ","pages":"Article 100033"},"PeriodicalIF":0.0,"publicationDate":"2024-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2790676024000049/pdfft?md5=cce421841e6722b30556c7033a866b71&pid=1-s2.0-S2790676024000049-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139727006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor microenvironment responsive nanozymes for multimodal imaging of tumors 用于肿瘤多模式成像的肿瘤微环境响应纳米酶
Nano TransMed Pub Date : 2024-01-29 DOI: 10.1016/j.ntm.2024.100032
Heng Wang , Wenrui Ouyang , Hongxing Liu
{"title":"Tumor microenvironment responsive nanozymes for multimodal imaging of tumors","authors":"Heng Wang ,&nbsp;Wenrui Ouyang ,&nbsp;Hongxing Liu","doi":"10.1016/j.ntm.2024.100032","DOIUrl":"https://doi.org/10.1016/j.ntm.2024.100032","url":null,"abstract":"<div><p>Nanozymes exhibit immense potential and promising prospects in the realm of diagnostic imaging and tumor therapy, owing to their inherent physicochemical properties and enzymatic activities. With the further development and application of nanotechnology, nanozymes are expected to become an important tool in the field of medicine, providing new solutions for disease diagnosis and treatment. This review provides an overview of recent studies over the past five years on the application of nanozymes capable of responding to the tumor microenvironment (TME) in multimodal imaging, with a focus on hypoxia, acid pH, excess GSH and ROS. In addition, we present the current status of the development of several common multimodal imaging and related contrast agents, such as MRI/CT, MRI/PET, MRI/SPECT, PET/CT. Moreover, some thoughts on the challenges, future development, and clinical translation of tumor microenvironment-responsive nanozymes in the field of multimodal imaging are shared. This review aims to provide an up-to-date theranostic nanomedicine reference for those who focus on related fields, promote the progress of this interdisciplinary subject, and accelerate clinical translation.</p></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"3 ","pages":"Article 100032"},"PeriodicalIF":0.0,"publicationDate":"2024-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2790676024000037/pdfft?md5=3d842eca16e677c7e3a844d36a3070b5&pid=1-s2.0-S2790676024000037-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139719744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quercetin-encapsulated GelMa hydrogel microneedle reduces oxidative stress and facilitates wound healing 包裹槲皮素的 GelMa 水凝胶微针可降低氧化应激并促进伤口愈合
Nano TransMed Pub Date : 2024-01-06 DOI: 10.1016/j.ntm.2024.100030
Yi Yi , Zihui Yang , Chuchao Zhou , Yanqing Yang , Yiping Wu , Qi Zhang
{"title":"Quercetin-encapsulated GelMa hydrogel microneedle reduces oxidative stress and facilitates wound healing","authors":"Yi Yi ,&nbsp;Zihui Yang ,&nbsp;Chuchao Zhou ,&nbsp;Yanqing Yang ,&nbsp;Yiping Wu ,&nbsp;Qi Zhang","doi":"10.1016/j.ntm.2024.100030","DOIUrl":"10.1016/j.ntm.2024.100030","url":null,"abstract":"<div><h3>Background</h3><p>Delayed wound healing brings additional physical, mental, and financial burdens. Microneedles (MNs) are a novel dressing form and can incorporate drug delivery systems. Quercetin is known for its remarkable antioxidant capacity and may have a distinctive effect on wound healing.</p></div><div><h3>Methods</h3><p>We designed and constructed gelatin methacryloyl (GelMa) MNs carrying Quercetin (Q-MNs). In vitro, the physical properties, cell safety, cell migration, angiogenesis, collagen formation, and oxidative stress levels, were performed to characterize Q-MNs. In vivo, the full-thickness skin wound models were established to evaluate the re-epithelialization and oxidative stress impact of the control, MN, and Q-MN groups.</p></div><div><h3>Results</h3><p>The Q-MNs were mechanically strong enough to penetrate the skin for sustained drug delivery and possessed good biocompatibility. Moreover, the Q-MNs evidently facilitated wound healing both in vitro and in vivo, and promoted collagen formation and neo-angiogenesis, and the reduction of oxidative stress levels.</p></div><div><h3>Conclusions</h3><p>The Q-MNs could motivate wound healing with enhanced collagen formation and vascularization and decreased oxidative stress levels, thus providing a feasible strategy for wound healing.</p></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"3 ","pages":"Article 100030"},"PeriodicalIF":0.0,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2790676024000013/pdfft?md5=c89128155b14ae18cb6e30a1c9431341&pid=1-s2.0-S2790676024000013-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139392454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomimetic nanocarriers harnessing microbial metabolites usher the path for brain disease therapy 利用微生物代谢物的仿生纳米载体为脑病治疗开辟了道路
Nano TransMed Pub Date : 2023-12-01 DOI: 10.1016/j.ntm.2023.100020
Ying Gong , Zhijun Liu , Piaopiao Zhou , Jiahong Li , Yang-Bao Miao
{"title":"Biomimetic nanocarriers harnessing microbial metabolites usher the path for brain disease therapy","authors":"Ying Gong ,&nbsp;Zhijun Liu ,&nbsp;Piaopiao Zhou ,&nbsp;Jiahong Li ,&nbsp;Yang-Bao Miao","doi":"10.1016/j.ntm.2023.100020","DOIUrl":"10.1016/j.ntm.2023.100020","url":null,"abstract":"<div><p>The gastrointestinal system, often regarded as the 'second brain of humanity,' maintains a profound connection with the cerebral realm. Unlocking the intricate metabolic pathways of gut microorganisms is paramount in the treatment of cerebral ailments. This review primarily focuses on biomimetic precision nanocarriers, harnessing metabolites derived from the gut microbiota, to target brain disorders. Elaborating on the constituents, it illuminates the unique interplay between metabolites originating from the gut microbiota and the cerebral domain. Moreover, the review underscores the symbiotic relationship between nanocarriers fashioned from gut microbiota-derived metabolites and the augmentation of cerebral well-being. Offering a comprehensive outlook, this review sheds light on recent applications, challenges, and future prospects of nanocarriers rooted in metabolites derived from the gut microbiota across a spectrum of disease treatments. It presents an expansive perspective on the attributes of nanocarriers engineered from gut microbiota-derived metabolites, facilitating a deeper understanding of the intricate nexus between these metabolites and cerebral disorders.</p></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"2 4","pages":"Article 100020"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2790676023000547/pdfft?md5=bb9b971517a72b43286dc639cd67e272&pid=1-s2.0-S2790676023000547-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138609031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements in modifying the efficacy of immunotherapies through the thermal effects of nanomaterials 通过纳米材料的热效应改变免疫疗法疗效的研究进展
Nano TransMed Pub Date : 2023-12-01 DOI: 10.1016/j.ntm.2023.100022
Lan Lei , Pengyuan Liu , Wu Jing , Zhibing Wu
{"title":"Advancements in modifying the efficacy of immunotherapies through the thermal effects of nanomaterials","authors":"Lan Lei ,&nbsp;Pengyuan Liu ,&nbsp;Wu Jing ,&nbsp;Zhibing Wu","doi":"10.1016/j.ntm.2023.100022","DOIUrl":"10.1016/j.ntm.2023.100022","url":null,"abstract":"<div><p>Tumor immunotherapy represents an intricate approach to combat tumors by modifying the immune microenvironment within the body. Nevertheless, the limited success rate and potential induction of systemic toxic reactions associated with immunotherapy introduce uncertainty regarding its therapeutic effectiveness. Nanoparticles (NPs) exhibit multifaceted applications as therapeutic and diagnostic tools, enabling precise delivery of various immunotherapeutic agents and monitoring of tissue cellular responses. These capabilities facilitate the dynamic assessment of factors influencing immune activity, thereby optimizing future treatment strategies. The utilization of multimodal anti-tumor therapies has paved the way for the induction of potent immune responses, while simultaneously minimizing adverse effects and facilitating the monitoring of immune activities.This review aims to provide an overview of this emerging field and highlight new technologies for next-generation immunotherapy. The current therapeutic approaches are introduced, and the mechanism of action of nanomaterials in combination with thermotherapy to stimulate systemic immune responses is explored. Furthermore, recent advancements in synergistic immunotherapy involving photothermal therapy (PPT) and magnetic hyperthermia therapy (MHT) for tumor treatment are highlighted, summarized, and extensively discussed.</p></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"2 4","pages":"Article 100022"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2790676023000560/pdfft?md5=6f62f481cf06abdac273cd756f7bc6ed&pid=1-s2.0-S2790676023000560-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138613992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hyperbolic shear polaritons and their potential applications 双曲剪切极化子及其潜在应用
Nano TransMed Pub Date : 2023-12-01 DOI: 10.1016/j.ntm.2023.100019
Guangyi Jia
{"title":"Hyperbolic shear polaritons and their potential applications","authors":"Guangyi Jia","doi":"10.1016/j.ntm.2023.100019","DOIUrl":"https://doi.org/10.1016/j.ntm.2023.100019","url":null,"abstract":"<div><p>Hyperbolic shear polaritons recently emerge with widespread attention as a new form of polariton modes with broken symmetry due to shear lattices. Herein, the generation mechanism of hyperbolic shear polaritons is discussed in detail. The exotic anisotropic nanophotonic properties of hyperbolic shear polaritons as well as their potential applications (e.g., ultra-sensitive biomedical sensor, enhancing the near-field thermal radiation and the photonic spin Hall effect) are reviewed. Some existing issues and potential interesting directions for hyperbolic shear polaritons are outlined. This work could inspire more interest in anisotropic two-dimensional crystals and spur the quick generation of new photonic devices based on hyperbolic polaritons.</p></div>","PeriodicalId":100941,"journal":{"name":"Nano TransMed","volume":"2 4","pages":"Article 100019"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2790676023000535/pdfft?md5=72b0c004cc646417d0a05941edd5a40c&pid=1-s2.0-S2790676023000535-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138739337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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