Chinese Chemical Letters最新文献

{"title":"A rechargeable and portable hydrogen storage system grounded on soda water","authors":"Lingyun Shen ,&nbsp;Shenxiang Yin ,&nbsp;Qingshu Zheng ,&nbsp;Zheming Sun ,&nbsp;Wei Wang ,&nbsp;Tao Tu","doi":"10.1016/j.cclet.2024.110580","DOIUrl":"10.1016/j.cclet.2024.110580","url":null,"abstract":"<div><div>The bicarbonate-formate (HCO₃⁻ – HCO₂⁻) interconversion provides a promising cycle for a conveniently accessible hydrogen storage system <em>via</em> reversible dehydrogenation and hydrogenation processes. Existing catalytic systems often use organic solvents, tedious optimization as well as manipulation of pH values, solvent, pressure and various additives. Herein, we present an operational, robust, safe and cost-effective catalytic system for hydrogen storage and liberation. We have established a unique catalytic system with two different solid organometallic assemblies (NHC-Ru and NHC-Ir) that facilitate the reversible transformation between sodium formate and bicarbonate in aqueous solutions collaboratively and efficiently. Notably, the NHC-Ru catalyst is privileged for the hydrogenation of sodium bicarbonate, whereas the NHC-Ir component enables the dehydrogenation of sodium formate, all in a single reaction vessel. What sets this system apart is its simplicity. The H₂ discharging and recharging is simply regulated by heating the mixture with or without H₂. Remarkably, this process requires no extra additives or supplementary treatments. Moreover, the reversible hydrogen storage system is durable and can be reused for over 30 cycles without a discernible decline in activity and selectivity. The strategic paradigm in this study shows significant practical potential in hydrogen fuel cell applications.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 3","pages":"Article 110580"},"PeriodicalIF":9.4,"publicationDate":"2024-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143318526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Triple-conducting heterostructure anodes for electrochemical ethane nonoxidative dehydrogenation by protonic ceramic electrolysis cells","authors":"Yixin Lu,&nbsp;Minghan Qin,&nbsp;Shixian Zhang,&nbsp;Zhen Liu,&nbsp;Wang Sun,&nbsp;Zhenhua Wang,&nbsp;Jinshuo Qiao,&nbsp;Kening Sun","doi":"10.1016/j.cclet.2024.110567","DOIUrl":"10.1016/j.cclet.2024.110567","url":null,"abstract":"<div><div>In response to the increasing demand of ethylene, electrochemical ethane nonoxidative dehydrogenation (EENDH) to ethylene by protonic ceramic electrolysis cells (PCECs) is developed. However, existing anode materials exhibit poor proton conductivity and limited catalytic activity. Herein, a novel Sr_1.95Fe_1.4Co_0.1Mo_0.4Zr_0.1O_6-<em>_δ</em> (SFCMZ) anode is prepared as PCECs anode for EENDH. Zr doping increases the oxygen vacancies and enhances the proton conductivity of SFCMZ. Moreover, an alloy-oxide heterostructure (CoFe@SFCMZ) is formed through <em>in-situ</em> exsolution of CoFe alloy nanoparticles under reduction conditions, generating abundant oxygen vacancies and improving its catalytic activity. CoFe@SFCMZ cell achieves an electrolysis current density of 0.87 A/cm² at 700 °C under 1.6 V, with an ethane conversion rate of 34.22% and corresponding ethylene selectivity of 93.4%. These results demonstrate that CoFe@SFCMZ anode exhibits excellent electrocatalytic activity, suggesting promising applications for EENDH.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 4","pages":"Article 110567"},"PeriodicalIF":9.4,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143098702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nd@C3N4-photoredox/chlorine dual catalyzed synthesis and evaluation of antitumor activities of 4-alkylated sulfonyl ketimines","authors":"Hong-Tao Ji ,&nbsp;Yu-Han Lu ,&nbsp;Yan-Ting Liu ,&nbsp;Yu-Lin Huang ,&nbsp;Jiang-Feng Tian ,&nbsp;Feng Liu ,&nbsp;Yan-Yan Zeng ,&nbsp;Hai-Yan Yang ,&nbsp;Yong-Hong Zhang ,&nbsp;Wei-Min He","doi":"10.1016/j.cclet.2024.110568","DOIUrl":"10.1016/j.cclet.2024.110568","url":null,"abstract":"<div><div>The first example of Nd@C₃N₄-photoredox/chlorine dual catalyzed alkylation with unactivated alkanes as the alkyl sources has been developed, which allows for the synthesis of various 4-alkylated cyclic sulfonyl ketimines. In this process, chlorine functions as both a redox and hydrogen atom transfer catalyst. The synergism of the reversible Nd²⁺/Nd³⁺ and Cl^¯/Cl˙ redox pairs significantly enhances overall photocatalytic efficiency. The <em>in vitro</em> anticancer activity of 4-alkylated products was evaluated by using the CCK8 assay against both human choroidal melanoma (MUM-2B) and lung cancer (A549) cell. Compound <strong>3da</strong> showed approximately triple the potency of 5-fluorouracil.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 2","pages":"Article 110568"},"PeriodicalIF":9.4,"publicationDate":"2024-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142657002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrotunable interfacial friction: A brief review","authors":"Yu Zhang ,&nbsp;Weifeng Lin","doi":"10.1016/j.cclet.2024.110566","DOIUrl":"10.1016/j.cclet.2024.110566","url":null,"abstract":"<div><div>Using different external stimuli to control interfacial friction, rather than just pursuing low friction, is a highly attractive research regime due to its economic and scientific importance. One option to achieve such a goal is to use external stimuli that modulate the energy dissipation pathways. In particular, electric stimuli such as surface potential has gained remarkable interest for two reasons: Electrotunable friction has the potential for real-time, <em>in situ</em> manipulation of friction, and external electric stimuli is relatively easy to apply and to remove for reversible change. In this review, we explore the emerging research area of electrotunable friction mainly under the boundary lubrication situation, when the contacting surfaces are separated by a molecularly thin layer, reviewing typical achievements from experiments using electrochemical atomic force microscopy and modified surface force balances, as well as molecular dynamics simulations. Additionally, we explore the theoretical and practical challenges that may need to be tackled in the future.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 4","pages":"Article 110566"},"PeriodicalIF":9.4,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intestinal transporters and oral absorption enhancing strategies based on these transporters","authors":"Ju Wang ,&nbsp;Yongbing Sun ,&nbsp;Lingbang Meng ,&nbsp;Jianfang Feng ,&nbsp;Meng Cheng ,&nbsp;Liangxing Tu","doi":"10.1016/j.cclet.2024.110529","DOIUrl":"10.1016/j.cclet.2024.110529","url":null,"abstract":"<div><div>Utilizing transporter-mediated drug delivery to achieve effective oral absorption emerges as a promising strategy. Researchers have been concentrated on discovering solutions to the issues of low solubility and poor permeability of insoluble drugs, whereas, current reports have revealed that drug transporter proteins are abundantly expressed in the mucosa of intestinal epithelial cells, and that their mediated drug absorption effectively improved the bioavailability of orally administered drugs. There are two main categories based on the transporter mechanism, which include the family of ATP-binding cassette (ABC) transporters with efflux effects that reduce drug bioavailability and the family of solute carriers (SLC) transporters with uptake effects that promote drug absorption, respectively. Thus, we review studies of intestinal transporter-mediated delivery of drugs to enhance oral absorption, including the types of intestinal transporters, distribution characteristics, and strategies for enhancing oral absorption using transporter-mediated drug delivery systems are summarized, with the aim of providing important theoretical references for the development of intestinal-targeted delivery system.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 5","pages":"Article 110529"},"PeriodicalIF":9.4,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143511715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unveiling and swift diagnosing chronic wound healing with artificial intelligence assistance","authors":"Jiliang Deng ,&nbsp;Guoliang Shi ,&nbsp;Zhihang Ye ,&nbsp;Quan Xiao ,&nbsp;Xiaoting Zhang ,&nbsp;Lei Ren ,&nbsp;Fangyu Yang ,&nbsp;Miao Wang","doi":"10.1016/j.cclet.2024.110496","DOIUrl":"10.1016/j.cclet.2024.110496","url":null,"abstract":"<div><div>Histopathological analysis of chronic wounds is crucial for clinicians to accurately assess wound healing progress and detect potential malignancy. However, traditional pathological tissue sections require specific staining procedures involving carcinogenic chemicals. This study proposes an interdisciplinary approach merging materials science, medicine, and artificial intelligence (AI) to develop a virtual staining technique and intelligent evaluation model based on deep learning for chronic wound tissue pathology. This innovation aims to enhance clinical diagnosis and treatment by offering personalized AI-driven therapeutic strategies. By establishing a mouse model of chronic wounds and using a series of hydrogel wound dressings, tissue pathology sections were periodically collected for manual staining and healing assessment. We focused on leveraging the pix2pix image translation framework within deep learning networks. Through CNN models implemented in Python using PyTorch, our study involves learning and feature extraction for region segmentation of pathological slides. Comparative analysis between virtual staining and manual staining results, along with healing diagnosis conclusions, aims to optimize AI models. Ultimately, this approach integrates new metrics such as image recognition, quantitative analysis, and digital diagnostics to formulate an intelligent wound assessment model, facilitating smart monitoring and personalized treatment of wounds. In blind evaluation by pathologists, minimal disparities were found between virtual and conventional histologically stained images of murine wound tissue. The evaluation used pathologists' average scores on real stained images as a benchmark. The scores for virtual stained images were 71.1 % for cellular features, 75.4 % for tissue structures, and 77.8 % for overall assessment. Metrics such as PSNR (20.265) and SSIM (0.634) demonstrated our algorithms' superior performance over existing networks. Eight pathological features such as epidermis, hair follicles, and granulation tissue can be accurately identified, and the images were found to be more faithful to the actual tissue feature distribution when compared to manually annotated data.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 3","pages":"Article 110496"},"PeriodicalIF":9.4,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143318382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amphibian-inspired conductive ionogel stabilizing in air/water as a wearable amphibious flexible sensor for drowning alarms","authors":"Yubin Feng ,&nbsp;Weihang Zhu ,&nbsp;Xinting Yang ,&nbsp;Zhe Yang ,&nbsp;Chenke Wei ,&nbsp;Yukai Guo ,&nbsp;Andrew K. Whittaker ,&nbsp;Chun Shen ,&nbsp;Yue Zhao ,&nbsp;Wenrui Qu ,&nbsp;Bai Yang ,&nbsp;Quan Lin","doi":"10.1016/j.cclet.2024.110554","DOIUrl":"10.1016/j.cclet.2024.110554","url":null,"abstract":"<div><div>Gel-based sensors have provided unprecedented opportunities for bioelectric monitoring. Until now, sensors for underwater applicants have remained a notable challenge, as most sensors work effectively in air but swell underwater leading to functional failure. Herein, we introduce an innovative amphibian-inspired high-performance ionogel, where multiple supramolecular interactions in the ionogel's network confer good stretchability, elasticity, conductivity, and the hydrophobic C-F bonds play a key role in diminishing water molecule hydration and provide outstanding environmental stability. These unique properties of ionogels make them suitable as wearable amphibious flexible sensors, and the sensors are capable of highly sensitive and stable human motion monitoring in air and underwater. Integration of the designed sensor into an artificial intelligence drowning alarm system, which recognizes the swimmer's movement status by monitoring the amplitude and frequency, especially in the drowning status for real-time alarms. This work provides novel strategies for motion recognition and hazard monitoring in amphibious environments, meeting the new generation of wearable sensors.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 4","pages":"Article 110554"},"PeriodicalIF":9.4,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143099323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Steric effects and electronic manipulation of multiple donors on S0/S1 transition of Dn-A emitters","authors":"Shunyu Wang ,&nbsp;Yanan Zhu ,&nbsp;Yang Zhao ,&nbsp;Wanli Nie ,&nbsp;Hong Meng","doi":"10.1016/j.cclet.2024.110555","DOIUrl":"10.1016/j.cclet.2024.110555","url":null,"abstract":"<div><div>Multiple donor-acceptor (D-A) combinations represent a promising category of thermally activated delayed fluorescence (TADF) materials, offering potential for superior efficiency and stability. However, current systems are predominantly composed of limited donor groups, primarily carbazole-based derivatives. In this work, we developed a series of D-A type materials incorporating helical <em>π</em>-expanded carbazole (CzNaph) and 7<em>H</em>-dinaphtho[1,8-<em>bc</em>:1′,8′-<em>ef</em>]azepine (AzNaph), alongside traditional carbazole, ranging from mono- to tetra-substituted configurations (D_n-A). Through systematic investigation of geometric and electronic structures, the number and positioning of multiple donors are confirmed with significant manipulations on charge transfer characteristics and the S₁ state <em>via</em> steric effects. Density functional theory (DFT) calculations reveal that varying the number of <em>π</em>-extended donors within the acceptor framework produces emission colors from ultraviolet to red, providing a diverse range of emitters. Furthermore, the reduced reorganization energy of S₁ observed in tetra-substituted Cz and CzNaph, as well as MonoAzN, indicates lower structural relaxation, highlighting these materials' potential as stable luminescent candidates. This study underscores the importance of diverse composing units in achieving efficient and stable TADF emitters with multiple and hetero-donor configurations.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 4","pages":"Article 110555"},"PeriodicalIF":9.4,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143149444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visible-light-induced photocatalyst- and metal-free radical phosphinoyloximation of alkenes with tert-butyl nitrite as bifunctional reagent","authors":"Huaixiang Yang ,&nbsp;Miao-Miao Li ,&nbsp;Aijun Zhang ,&nbsp;Jiefei Guo ,&nbsp;Yongqi Yu ,&nbsp;Wei Ding","doi":"10.1016/j.cclet.2024.110425","DOIUrl":"10.1016/j.cclet.2024.110425","url":null,"abstract":"<div><div>The <em>tert</em>-butyl nitrite as a bifunctional reagent mediated radical alkene difunctionalization has emerged as a powerful strategy for synthesis of structurally diverse oxime-containing compounds. However, the phosphorus-centered radical initiated transformations remain largely elusive. Herein, a visible-light-induced radical phosphinoyloximation of alkenes with secondary phosphine oxides and <em>tert</em>-butyl nitrite has been developed under photocatalyst- and metal-free conditions. This protocol features mild conditions, broad substrate scope, good functional tolerance, and operational simplicity, yielding a diverse array of α-phosphinoyl oximes in moderate to good yields with high stereoselectivities. The photomediated homolytic cleavage of O<img>NO bond of <em>tert</em>-butyl nitrite generates the reactive <em>tert</em>-butoxyl radical and persistent NO radical to act as both HAT reagent and the source of oximes.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 3","pages":"Article 110425"},"PeriodicalIF":9.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143318525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Innovative self-healing conductive organogel: Pioneering the future of electronics","authors":"Salim Ullah ,&nbsp;Jianliang Shen ,&nbsp;Hong-Tao Xu","doi":"10.1016/j.cclet.2024.110553","DOIUrl":"10.1016/j.cclet.2024.110553","url":null,"abstract":"","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"36 3","pages":"Article 110553"},"PeriodicalIF":9.4,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143356468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}