Chinese Chemical Letters最新文献_第7页

Atom-swapping skeletal editing of benzo[c]oxepines for the construction of 2-benzodiazepines via a continuous manufacturing one-pot synthesis 苯并[c]氧平类药物的原子交换骨架编辑，通过连续制造一锅合成构建2-苯二氮卓类药物

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-04-01 Epub Date: 2025-04-11 DOI: 10.1016/j.cclet.2025.111200

Jun-Gang Wang , Bing-Yi Zhou , Yao-Luo Hu , Yong-Dong Du , Rong-He Wu , Chun-Yan Wu , Wen-Chao Yang , An-Xin Wu

引用次数: 0

A highly efficient approach to Z-monofluoroolefin-dehydroamino acid derivatives from gem-difluoroalkenes 从宝石-二氟烯烃制备z -单氟烯烃-脱氢氨基酸衍生物的高效方法

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-04-01 Epub Date: 2025-04-02 DOI: 10.1016/j.cclet.2025.111167

Chuangchuang Liu , Yilian Song , Wenjie Ju , Xin Liu , Min Liang , Yingsheng Zhao

引用次数: 0

Enhanced electrochemical performance of anthraquinone-based cathode for sodium ion batteries by π-conjugated structure 用π共轭结构增强蒽醌基钠离子电池阴极的电化学性能

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-04-01 Epub Date: 2025-09-24 DOI: 10.1016/j.cclet.2025.111881

Xiaotong Deng , Zetao Wu , Anna Zhou , Shuo-Hang Zheng , Ziheng Cheng , Guangming Li , Yun Zhao , Ronghua Zeng , Nguyen Duc Hoa , Xing-Long Wu

{"title":"Enhanced electrochemical performance of anthraquinone-based cathode for sodium ion batteries by π-conjugated structure","authors":"Xiaotong Deng , Zetao Wu , Anna Zhou , Shuo-Hang Zheng , Ziheng Cheng , Guangming Li , Yun Zhao , Ronghua Zeng , Nguyen Duc Hoa , Xing-Long Wu","doi":"10.1016/j.cclet.2025.111881","DOIUrl":"10.1016/j.cclet.2025.111881","url":null,"abstract":"<div><div>Quinone-based electrode materials hold significant promise for next-generation sodium-ion batteries due to their structurally tailorable frameworks, high theoretical capacities, and favorable redox potentials. However, dissolution in organic electrolytes and structural instability during cycling critically impair their capacity retention and cycling durability. Herein, we designed and synthesized two novel acylimide materials <em>N,N</em>'-bis(2,6-anthraquinone diamine)-biphenyl diimide (DQ-BDI) and <em>N,N</em>'-bis(anthraquinone-2,6-diamine)-perylenyl diimide (DQ-PDI) with the gradual enhancement of <em>π</em>-conjugation. Electrochemical characterization reveals exceptional performance in DQ-PDI. At the current density of 50 mA/g, the DQ-PDI delivered the first discharge specific capacity of 158 mAh/g, and the capacity retention of 99 % after 100 cycles, with the coulombic efficiency of nearly 100 %. At a high current density of 500 mA/g, the DQ-PDI displays a high discharge capacity of 152 mAh/g. The reduction peaks of DQ-PDI located at 2.28 V and 1.34 V are the insertion reactions of sodium ion from the carbonyl groups on PTCDA unit and on DAAQ unit at both ends, respectively, and the two oxidation peaks at 2.58 V and 1.53 V corresponds to extraction reactions. Compared with DQ-BDI, DQ-PDI exhibits a larger <em>π</em>-conjugation plane, which significantly enhances the intermolecular <em>π</em>-<em>π</em> interactions. It can well reduce the dissolution of the material in organic electrolyte, resulting in a higher discharge capacity, superior cycling stability and accelerated reaction kinetics. Our <em>π</em>-conjugation extension strategy establishes a new paradigm for designing dissolution-resistant, high-performance organic electrodes.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 4","pages":"Article 111881"},"PeriodicalIF":8.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146074254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lignin valorization towards porous carbon cathodes in zinc ion hybrid capacitors 木质素在锌离子杂化电容器多孔碳阴极上的增值

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-04-01 Epub Date: 2025-09-17 DOI: 10.1016/j.cclet.2025.111850

Caiwei Wang , Cheng Zeng , Changhong Wei , Guizhen Chen , Yueling Liang , Wenli Zhang

{"title":"Lignin valorization towards porous carbon cathodes in zinc ion hybrid capacitors","authors":"Caiwei Wang , Cheng Zeng , Changhong Wei , Guizhen Chen , Yueling Liang , Wenli Zhang","doi":"10.1016/j.cclet.2025.111850","DOIUrl":"10.1016/j.cclet.2025.111850","url":null,"abstract":"<div><div>Zinc ion hybrid capacitors (ZIHCs) are emerging electrochemical energy storage devices with the dual characteristics of high energy density and high power density. However, the mismatch of capacity and electrode kinetics between porous carbon cathodes and zinc metal anodes limits the development of ZIHCs. Lignin has high carbon content, high aromaticity, and three-dimensional functional molecular structures, which is an ideal raw material for preparing high-performance porous carbon electrode materials with high carbon yield, conductive carbon network and enriched heteroatom dopants. Currently, the high-value utilization ratio of industrial lignin is lower than 10%. In this review, the typical preparation methodologies of lignin-derived porous carbons are summarized. The latest research advances for the lignin-derived porous carbon cathodes in ZIHCs are critically focused from the perspectives of pore regulation, surface modification, and morphology design. The core points and development directions that lignin-derived porous carbon cathodes are expected to achieve an original breakthrough in the future are proposed from three levels of techniques, mechanisms, and applications. This review fills the blank region in the applications of lignin-derived porous carbons for ZIHCs, aiming to provide valuable guidance for the high-value utilization process of lignin and the industrialization process of ZIHCs.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 4","pages":"Article 111850"},"PeriodicalIF":8.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A microfluidic biosensor for rapid detection of live bacteria based on immune magnetic separation and photothermal lysis of gold nanorods 一种基于免疫磁分离和光热裂解金纳米棒的活菌快速检测微流控生物传感器

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-04-01 Epub Date: 2025-08-11 DOI: 10.1016/j.cclet.2025.111704

Nan Li , Weifei Zhang , Gaowa Xing , Zengnan Wu , Xiaorui Wang , Ling Lin

{"title":"A microfluidic biosensor for rapid detection of live bacteria based on immune magnetic separation and photothermal lysis of gold nanorods","authors":"Nan Li , Weifei Zhang , Gaowa Xing , Zengnan Wu , Xiaorui Wang , Ling Lin","doi":"10.1016/j.cclet.2025.111704","DOIUrl":"10.1016/j.cclet.2025.111704","url":null,"abstract":"<div><div>Foodborne bacterial infection is a serious threat to food safety, especially live pathogens causing outbreaks of most diseases. Thus developing live bacterial detection methods is important for public health. In this study, a microfluidic biosensor was developed for rapid detection of live <em>Salmonella typhimurium</em>, in which immune magnetic particle chains in microchannels were used to separate and enrich target bacteria, antibody-conjugated gold nanorods (GNRs) were applied for photothermal lysis of target live bacteria under near-infrared (NIR) irradiation, and a photon-counting detector was used for measuring adenosine triphosphate (ATP) bioluminescence in the presence of firefly luciferin/luciferase. This biosensor was proved to be able to quantitatively detect <em>S. typhimurium</em> from 5.0 × 10<sup>2</sup> CFU/mL to 5.0 × 10<sup>6</sup> CFU/mL in 60 min (magnetic separation 20 min; GNRs combination 20 min; NIR irradiation, 8 min) with limit of detection (LOD) of 495 CFU/mL. This biosensor showed an excellent specificity in the coexistence of other foodborne bacteria, and target bacteria were successfully measured even in the matrix interference of milk sample with mean recovery of 121.17 %. This biosensor might be a promising tool for on-site assessment foodborne bacteria.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 4","pages":"Article 111704"},"PeriodicalIF":8.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146035434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breakthrough progress in the structural determination of the monkeypox virus I7L protease and the design of targeted inhibitors 猴痘病毒I7L蛋白酶结构测定及靶向抑制剂设计的突破性进展

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-04-01 Epub Date: 2025-09-16 DOI: 10.1016/j.cclet.2025.111845

Linan Wu, Shenghua Gao, Peng Zhan

引用次数: 0

Self-assembled cyclodextrin-porphyrin nanoplatform for synergistic chemo-phototherapy and targeted delivery of camptothecin against breast cancer 自组装环糊精-卟啉纳米平台协同化疗-光疗和靶向递送喜树碱对抗乳腺癌

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-04-01 Epub Date: 2025-09-25 DOI: 10.1016/j.cclet.2025.111901

Jiaojiao Yang , Shaokun Yang , Wei Cheng , Jie Wu , Haijing Qu , Han Chen , Zhiran Duan , Yuqing Pan , Ning Wang , Chao Wang , Jian Gao , Bai Xiang , Xiangdong Xue

{"title":"Self-assembled cyclodextrin-porphyrin nanoplatform for synergistic chemo-phototherapy and targeted delivery of camptothecin against breast cancer","authors":"Jiaojiao Yang , Shaokun Yang , Wei Cheng , Jie Wu , Haijing Qu , Han Chen , Zhiran Duan , Yuqing Pan , Ning Wang , Chao Wang , Jian Gao , Bai Xiang , Xiangdong Xue","doi":"10.1016/j.cclet.2025.111901","DOIUrl":"10.1016/j.cclet.2025.111901","url":null,"abstract":"<div><div>The management of breast cancer remains clinically intractable, driven by its highly invasive behavior and limited susceptibility to conventional treatments. In this study, we engineered an innovative cyclodextrin-porphyrin co-assembled nanoplatform (CT NPs) to enable multimodal breast cancer therapy. By successfully encapsulating camptothecin (CPT) within this nanocarrier, the system (CTC NPs) achieved synergistic chemo-phototherapeutic efficacy through dual-modality action. The highly biocompatible cyclodextrin carrier significantly improved the physicochemical characteristics of CPT. <em>In vivo</em> studies revealed that CTC NPs effectively evaded clearance by the reticuloendothelial system, overcame the defect of premature drug leakage, and exhibited superior tumor targeting and infiltration capabilities. Under near-infrared (NIR) laser irradiation, CTC NPs can simultaneously induce localized hyperthermia and produce reactive oxygen species (ROS), thereby achieving efficient tumor ablation. In 4T1 tumor-bearing mice, CTC NPs exhibited targeted, safe, and highly potent anti-tumor efficacy, significantly suppressing both primary tumor progression (tumor suppression rate > 95 %) and metastatic dissemination. In summary, this integrated nanoplatform establishes a novel theranostic paradigm for synergistic chemo-phototherapy against triple-negative breast cancer (TNBC), achieving precise tumor ablation through NIR-triggered drug release and real-time imaging guidance.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 4","pages":"Article 111901"},"PeriodicalIF":8.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Silver coordination-directed double-stranded polyrotaxanes with supramolecular isomerism and dual stimuli-responsiveness 具有超分子异构体和双重刺激反应的银配位定向双链聚轮烷

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-04-01 Epub Date: 2025-04-30 DOI: 10.1016/j.cclet.2025.111279

Yan Lou , Wei Jin , Zhiwei Huang , Yuanyuan Liang , Kongqiu Hu , Liyong Yuan , Lingling Su , Changchun Zhao , Weiqun Shi , Lei Mei

{"title":"Silver coordination-directed double-stranded polyrotaxanes with supramolecular isomerism and dual stimuli-responsiveness","authors":"Yan Lou , Wei Jin , Zhiwei Huang , Yuanyuan Liang , Kongqiu Hu , Liyong Yuan , Lingling Su , Changchun Zhao , Weiqun Shi , Lei Mei","doi":"10.1016/j.cclet.2025.111279","DOIUrl":"10.1016/j.cclet.2025.111279","url":null,"abstract":"<div><div>Hierarchical assembly provides a rational procedure to acquire complex supramolecular architectures from basic building blocks. In this work, a novel kind of double-stranded polyrotaxane motif was reported by Ag<sup>+</sup>-directed coordination-driven assembly following the preassembly of a four-connected pseudorotaxane (cpb)<sub>2</sub><sub><img></sub>CB8 linker. Moreover, supramolecular isomerism is observed in crystalline compounds based on double-stranded polyrotaxane motifs due to differences in lattice stacking mode. Interestingly, the resultant supramolecular isomers, cross-Ag-DSP-1 and para-Ag-DSP-1, show dual thermo- and anion-responsiveness. Benefiting from high crystallinity of these coordination assemblies, a combination of characterization techniques, especially X-ray diffraction, was used to unveil precise molecular mechanisms related to the inherent dynamic behavior of these assemblies, which can be attributed to remarkable lattice rearrangement and crystal transformations as temperature increases or after anion exchange, reflecting the adaptive adjustment ability of these supramolecular architectures in response to external stimuli. Based on the anion exchange capability, these two supramolecular materials show fast removal kinetics and high sorption capacity for perrhenate (ReO<sub>4</sub><sup>-</sup>) anion, a surrogate of radioactive pertechnetate (TcO<sub>4</sub><sup>-</sup>) in nuclear waste eluents. This work provides a feasible way to supramolecular assemblies with customized structures and stimuli-responsiveness, and is helpful to design and synthesize more functional supramolecular systems with complex structures and tailored functions.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 4","pages":"Article 111279"},"PeriodicalIF":8.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biomimetic NIR-II fluorescent probe from covalent encapsulation enables high-performance NIR-II bioimaging 共价封装的仿生NIR-II荧光探针可实现高性能的NIR-II生物成像

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-04-01 Epub Date: 2025-05-20 DOI: 10.1016/j.cclet.2025.111351

Zijian Jiang , Yijing Du , Zetao Dang , Tongze Liu , Mengyuan Liu , Bin Sun , Feiran Zhang , Jiajun Xu , Shoujun Zhu

{"title":"Biomimetic NIR-II fluorescent probe from covalent encapsulation enables high-performance NIR-II bioimaging","authors":"Zijian Jiang , Yijing Du , Zetao Dang , Tongze Liu , Mengyuan Liu , Bin Sun , Feiran Zhang , Jiajun Xu , Shoujun Zhu","doi":"10.1016/j.cclet.2025.111351","DOIUrl":"10.1016/j.cclet.2025.111351","url":null,"abstract":"<div><div>To promote the advantages of near-infrared-II (NIR-II) imaging, researchers have developed various types of NIR-II imaging contrast agents, with conjugated dyes being one of the most important categories. However, hydrophobic dyes often rely on encapsulation with amphiphilic polymers for biological applications, which lead to brightness quenching and instability <em>in vivo</em>. To address this, we proposed a covalent encapsulation strategy to transform the hydrophobic dye from organic solvent to aqueous solution. To achieve this, we designed a chlorine-containing NIR-II cyanine dye (C7–1080), which covalently binds to human serum albumin (HSA), forming a stable NIR-II fluorescent probe, HSA@C7–1080. The HSA@C7–1080 has precise molecular weight and spatial structure, making dye monodispersing in the albumin pocket with improved fluorescence and stability. This NIR-II fluorescent probe provides high-resolution NIR-II imaging in various biological systems. Our strategy offers a promising alternative for the clinical translation of hydrophobic NIR-II dyes, improving their biocompatibility and imaging performance in fluorescence-guided surgery.</div></div>","PeriodicalId":10088,"journal":{"name":"Chinese Chemical Letters","volume":"37 4","pages":"Article 111351"},"PeriodicalIF":8.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145974783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A conformationally adaptive cage with multiple guest recognition modes 具有多种客人识别模式的构象自适应笼

IF 8.9 1区化学

Chinese Chemical Letters Pub Date : 2026-04-01 Epub Date: 2025-05-20 DOI: 10.1016/j.cclet.2025.111354

Yongwei Qian , Shengyang Huang , Yaoyi Su , Songna Zhang , Yang Liu , Ming Liu , Bin Sun , Hao Li

引用次数: 0