Journal of Veterinary Anaesthesia最新文献_第5页

Endocrine and metabolic responses to halothane and pentobarbitone anaesthesia in sheep 氟烷和戊巴比酮麻醉对绵羊内分泌和代谢的影响

Journal of Veterinary Anaesthesia Pub Date : 1998-07-01 DOI: 10.1111/J.1467-2995.1998.TB00165.X

P. Taylor

{"title":"Endocrine and metabolic responses to halothane and pentobarbitone anaesthesia in sheep","authors":"P. Taylor","doi":"10.1111/J.1467-2995.1998.TB00165.X","DOIUrl":"https://doi.org/10.1111/J.1467-2995.1998.TB00165.X","url":null,"abstract":"SUMMARY Some metabolic and endocrine responses to anaesthesia in sheep were studied. Adult sheep were anaesthetised with thiopentone and halothane (n=9), acepromazine, thiopentone and halothane (n=8) and pentobarbitone (n=10) on separate occasions. Routine cardiovascular monitoring was carried out and blood samples were taken for assay of cortisol, adrenocorticotrophic hormone (ACTH), arginine vasopressin (AVP), glucose and lactate. Halothane anaesthesia induced hypotension, hypercapnia and respiratory acidosis. Sheep anaesthetised with pentobarbitone were also hypercapnic and acidotic but did not develop hypotension. Plasma cortisol, ACTH and AVP (mean maximum values: cortisol: 83 ng/ml, ACTH 278 ng/ml, AVP 135 pg/ml), increased during halothane anaesthesia but did not change significantly from control values during pentobarbitone anaesthesia (mean maximum values: cortisol: 30 ng/ml, ACTH 71 ng/ml, AVP 7.8 pg/ml). Glucose tended to increase during both halothane and pentobarbitone anaesthesia but lactate decreased. It is not clear what facet of halothane anaesthesia evokes the stress response but it may be associated with cardiovascular depression.","PeriodicalId":100854,"journal":{"name":"Journal of Veterinary Anaesthesia","volume":"3 1","pages":"24-30"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76800917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

The effect of epidural morphine on the minimum alveolar concentration of isoflurane in cats 硬膜外吗啡对猫肺泡最低异氟醚浓度的影响

Journal of Veterinary Anaesthesia Pub Date : 1998-07-01 DOI: 10.1111/j.1467-2995.1998.tb00170.x

F.J. Golder, P.J. Pascoe, C.S. Bailey, J.E. Ilkiw, L.D. Tripp

{"title":"The effect of epidural morphine on the minimum alveolar concentration of isoflurane in cats","authors":"F.J. Golder, P.J. Pascoe, C.S. Bailey, J.E. Ilkiw, L.D. Tripp","doi":"10.1111/j.1467-2995.1998.tb00170.x","DOIUrl":"https://doi.org/10.1111/j.1467-2995.1998.tb00170.x","url":null,"abstract":"<div><p>This study was undertaken to evaluate the effect of 3 different doses of epidurally administered morphine sulphate on the minimum alveolar concentration (MAC) of isoflurane in healthy cats. Five 4-year-old, spayed female cats weighing 4.7 ± 0.8 kg were allocated randomly to receive one of 3 doses of morphine on each study day. The 3 doses of morphine were 0.05, 0.1 and 0.2 mg/kg bwt and each cat was studied 3 times so that each cat received all doses. On each study day, cats were anaesthetised with isoflurane and instrumented. The MAC of isoflurane was determined in triplicate and morphine sulphate was administered via an epidural catheter chronically implanted prior to the study. Maximum MAC reduction was determined over the following 2 h. At the end of the study cats were allowed to recover. There was a significant reduction in MAC of isoflurane, with all doses of epidural morphine (P<0.05). The maximum reduction in MAC of isoflurane after 0.05 mg/kg bwt, 0.10 mg/kg bwt and 0.20 mg/kg bwt morphine was 21.4 ± 9.796, 30.8 ± 9.696, and 30.2 ± 6.8%, respectively, with no significant difference between doses. Systolic, mean and diastolic blood pressure, heart rate, respiratory rate and arterial pH decreased significantly whereas arterial carbon dioxide tension increased significantly after morphine administration (P<0.05). The means for all variables returned to pre-morphine values when the end-tidal isoflurane concentration was reduced to the new MAC point. In conclusion, epidural morphine decreased the concentration of isoflurane required to prevent movement in response to noxious mechanical stimulation to the tail base. A similar effect may be seen clinically allowing lower doses of isoflurane to be used to provide surgical anaesthesia for procedures involving the hind limbs, pelvis and tail.</p></div>","PeriodicalId":100854,"journal":{"name":"Journal of Veterinary Anaesthesia","volume":"25 1","pages":"Pages 52-56"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1467-2995.1998.tb00170.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72283378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 32

Comparing oral and intramuscular administration of medetomidine in cats 猫口服和肌肉注射美托咪定的比较

Journal of Veterinary Anaesthesia Pub Date : 1998-07-01 DOI: 10.1111/J.1467-2995.1998.TB00168.X

O. B. Ansah, M. Raekallio, O. Vainio

引用次数: 20

The pharmacokinetics of ketamine after a continuous infusion under halothane anaesthesia in horses 氟烷麻醉下持续输注氯胺酮在马体内的药代动力学

Journal of Veterinary Anaesthesia Pub Date : 1998-07-01 DOI: 10.1111/J.1467-2995.1998.TB00166.X

D. Flaherty, J. Reid, A. Nolan, A. Monteiro

{"title":"The pharmacokinetics of ketamine after a continuous infusion under halothane anaesthesia in horses","authors":"D. Flaherty, J. Reid, A. Nolan, A. Monteiro","doi":"10.1111/J.1467-2995.1998.TB00166.X","DOIUrl":"https://doi.org/10.1111/J.1467-2995.1998.TB00166.X","url":null,"abstract":"SUMMARY The pharmacodynamics and pharmacokinetics of ketamine, when administered by infusion as an adjunct to halothane anaesthesia in horses, were investigated in 5 equine patients presented for routine castration. Anaesthesia was induced with detomidine, 20 μg/kg, followed by ketamine, 2.2 mg/kg bwt, the trachea intubated and the horses allowed to breathe halothane in oxygen. Five minutes later, a constant rate infusion of ketamine, 40 μg/kg min, was commenced and the halothane vaporiser concentration adjusted to maintain a light plane of anaesthesia. The mean infusion duration was 62 min (range 40–103). The ketamine was switched off approximately 15 min before the halothane. Plasma ketamine and norketamine levels, determined by high performance liquid chromatography, ranged from 0.74–2.04 μg/ml and 0.15–0.75 μg/ml, respectively, during the infusion period. The harmonic mean elimination half-life of ketamine was 46.1 min, mean volume of distribution at steady state (Vdss) was 1365 (271) ml/kg, mean body clearance (Cl) was 32.3 (9.1) ml/min.kg, and average mean residence time for the infusion (MRTinf) was 105.9 (20.4) min, respectively. Following termination of halothane, mean times to sternal recumbency and standing were 21.1 (6.9) and 41.6 (17.0) min, respectively. Surgical conditions were considered highly satisfactory, and physiological parameters were well preserved in most animals.","PeriodicalId":100854,"journal":{"name":"Journal of Veterinary Anaesthesia","volume":"6 1","pages":"31-36"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84739690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

Changes in heart rate, mean arterial pressure, blood biochemistry, plasma glucose, plasma lactate and some plasma enzymes during sufentanil/halothane anaesthesia in horses 舒芬太尼/氟烷麻醉期间马心率、平均动脉压、血液生化、血浆葡萄糖、血浆乳酸和一些血浆酶的变化

Journal of Veterinary Anaesthesia Pub Date : 1998-07-01 DOI: 10.1111/J.1467-2995.1998.TB00163.X

P. Dijk, S. K. Nyks

{"title":"Changes in heart rate, mean arterial pressure, blood biochemistry, plasma glucose, plasma lactate and some plasma enzymes during sufentanil/halothane anaesthesia in horses","authors":"P. Dijk, S. K. Nyks","doi":"10.1111/J.1467-2995.1998.TB00163.X","DOIUrl":"https://doi.org/10.1111/J.1467-2995.1998.TB00163.X","url":null,"abstract":"SUMMARY Nine horses were each anaesthetised for 40 min using SufentaniVhalothane. No surgery was performed. After premedication (detomidine 5 pgkg bwt iv) induction of anaesthesia was achieved by a combination of guaiphenesinlthiopentone. Anaesthesia was maintained by inhalation of halothane (0.8%) in oxygen. Six horses (Group 1) received 1 pgkg bwt sufentanil followed by a second injection (1 pg/kg bwt) after 20 min. Three horses (Group 2) received 2 pg/kg bwt sufentanil also followed by a second injection (2 pg/kg bwt) after 20 min. Each sufentanil injection produced a slight decrease in mean arterial blood pressure with a gradual return to the initial pressure. Bradycardia was also observed. Sufentanil injection induced apnoea needing artificial ventilation. Arterial blood was sampled for analysis during the anaesthetic procedure. At the end of anaesthesia, 1 h and 24 h after rising, venous blood was sampled to determine concentrations of lactate dehydrogenase (LDH), aspartate aminotransferase (AST) and creatine phosphokinase (CPK). Values obtained were compared with values in blood taken before premedication. Plasma glucose and lactate concentrations just before sufentanil administration, at the end of anaesthesia and 1 h after rising were compared to control values. Plasma glucose concentration increased significantly during anaesthesia but returned to normal values 1 h after rising. All other parameters stayed within physiological ranges. In both groups spontaneous respiration returned 20–25 min after the second sufentanil injection. Recovery was uneventful.","PeriodicalId":100854,"journal":{"name":"Journal of Veterinary Anaesthesia","volume":"85 1","pages":"13-18"},"PeriodicalIF":0.0,"publicationDate":"1998-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83880154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

ABSTRACTS OF SCIENTIFIC PAPERS PRESENTED AT THE SPRING MEETING OF THE ASSOCIATION OF VETERINARY ANAESTHETISTS, LONDON, 7TH-8TH APRIL 1997 1997年4月7日至8日在伦敦举行的兽医麻醉师协会春季会议上发表的科学论文摘要

Journal of Veterinary Anaesthesia Pub Date : 1997-12-01 DOI: 10.1111/j.1467-2995.1997.tb00154.x

引用次数: 0

ECVA - Past, present and future ECVA -过去，现在和未来

Journal of Veterinary Anaesthesia Pub Date : 1997-12-01 DOI: 10.1111/J.1467-2995.1997.TB00147.X

U. Schatzmann

引用次数: 1

Association of Veterinary Anaesthetists: An Introduction to the Association 兽医麻醉师协会简介

Journal of Veterinary Anaesthesia Pub Date : 1997-12-01 DOI: 10.1111/j.1467-2995.1997.tb00156.x

引用次数: 0

Armoured endotracheal tube—complications with use in pigs 铠装气管插管——在猪身上使用的并发症

Journal of Veterinary Anaesthesia Pub Date : 1997-12-01 DOI: 10.1111/j.1467-2995.1997.tb00153.x

R.E. Clutton , A. Lawrence

引用次数: 3

A simple method to correct infrared measurement of anaesthetic vapour concentration in the presence of methane 一种在甲烷存在下校正麻醉蒸气浓度红外测量的简单方法

Journal of Veterinary Anaesthesia Pub Date : 1997-12-01 DOI: 10.1111/J.1467-2995.1997.TB00152.X

P. Gootjes, Y. Moens

引用次数: 2