Journal of Veterinary Anaesthesia最新文献

Emeritus Professor J.E. Utting 荣休教授J.E.尤廷

Journal of Veterinary Anaesthesia Pub Date : 1999-12-01 DOI: 10.1111/j.1467-2995.1999.tb00181.x

Professor Ron Jones

引用次数: 0

The effect of guaiphenesin on romifidine/ketamine anaesthesia in ponies 愈创酚素对罗米非定/氯胺酮麻醉小马的影响

Journal of Veterinary Anaesthesia Pub Date : 1999-12-01 DOI: 10.1111/J.1467-2995.1999.TB00180.X

K. Walsh, J. Brearley, K. Lakhani, A. Raisis, L. E. Young

引用次数: 1

Notes for Contributors 投稿人须知

Journal of Veterinary Anaesthesia Pub Date : 1999-12-01 DOI: 10.1111/j.1467-2995.1999.tb00187.x

引用次数: 0

Bispectral index as an indicator of anaesthetic depth during isoflurane anaesthesia in the pig 猪异氟烷麻醉过程中作为麻醉深度指标的双光谱指数

Journal of Veterinary Anaesthesia Pub Date : 1999-12-01 DOI: 10.1111/j.1467-2995.1999.tb00175.x

H.A. Haga, A. Tevik, H. Moerch

{"title":"Bispectral index as an indicator of anaesthetic depth during isoflurane anaesthesia in the pig","authors":"H.A. Haga, A. Tevik, H. Moerch","doi":"10.1111/j.1467-2995.1999.tb00175.x","DOIUrl":"https://doi.org/10.1111/j.1467-2995.1999.tb00175.x","url":null,"abstract":"<div><p>The objective of the study was to examine the relationship between the ‘depth’ of anaesthesia - as determined by clinical signs - and the bispectral index (BIS). Electroencephalograms (EEG)s were recorded in 8 female and 8 castrated male, healthy Norwegian landrace pigs undergoing isoflurane anaesthesia, from which the bispectral index (BIS) was calculated. Isoflurane was delivered in pure oxygen at end-tidal concentrations of 1.6, 1.9, 2.2 and 2.5%, in randomised order, for 30 min after which the EEG was recorded over a 5 min period. Anaesthetic depth was evaluated on a visual analogue scale (VAS) by an experienced anaesthetist. The 95% confidence interval for the mean correlation coefficient between BIS and VAS was calculated to be -0.52–0.30. Confidence intervals (95%) for the mean change in the BIS obtained during the conscious state and that obtained during anaesthesia at different isoflurane concentrations was also calculated. There was a significant decrease in the BIS recorded during consciousness and after 1.6% isoflurane anaesthesia, and between readings after inhalation of 2.2% and 2.5% isoflurane. This indicates that BIS does not accurately reflect ‘depth’ at surgical levels of isoflurane anaesthesia in the pig, and is of no use for this purpose.</p></div>","PeriodicalId":100854,"journal":{"name":"Journal of Veterinary Anaesthesia","volume":"26 1","pages":"Pages 3-7"},"PeriodicalIF":0.0,"publicationDate":"1999-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1467-2995.1999.tb00175.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72241873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 35

Actions and pharmacokinetic properties of the α2‐adrenergic agents, medetomidine and atipamezole, in rainbow trout (Oncorhynchus mykiss) α2‐肾上腺素能药物美托咪定和阿替帕唑在虹鳟鱼体内的作用及药动学性质

Journal of Veterinary Anaesthesia Pub Date : 1999-12-01 DOI: 10.1111/J.1467-2995.1999.TB00179.X

T. E. Horsberg, J. Burka, R. Tasker

{"title":"Actions and pharmacokinetic properties of the α2‐adrenergic agents, medetomidine and atipamezole, in rainbow trout (Oncorhynchus mykiss)","authors":"T. E. Horsberg, J. Burka, R. Tasker","doi":"10.1111/J.1467-2995.1999.TB00179.X","DOIUrl":"https://doi.org/10.1111/J.1467-2995.1999.TB00179.X","url":null,"abstract":"SUMMARY The effects of medetomidine and atipamezole were examined in rainbow trout. Medetomidine proved to be an effective sedative but not an anaesthetic; its effects were antagonised by atipamezole. The clinical signs of medetomidine sedation were rapid settling to the bottom of the tank followed by progressive ataxia. The sedative effect was dose-dependent: at 1 mg/l, one of 6 fish rested on its side after 10 min, whereas at 20 mg/l all 6 rested on their sides. No loss of consciousness occurred. Atipamezole at 6 times the medetomidine concentration antagonised sedation. The average time before fish exposed to medetomidine alone showed avoidance reactions was 10 h, more than 5 times longer than the mean time in fish exposed to medetomidine and then atipamezole. During exposure to medetomidine (5 mg/l) opercular movement rate decreased from 80/min to 20/min. The nature of opercular excursions also changed from being rapid and shallow to slow and deep. Respiratory movements increased after transfer to the bath containing atipamezole. Medetomidine had a marked effect upon skin colour, with fish becoming very pale a few min after exposure. Normal pigmentation was not restored until 4.5 days after exposure to medetomidine alone, but returned to normal after 10 min exposure to atipamezole solution. The half-life ( t 1 / 2 lambda z ) for medetomidine was 5.5 h. For atipamezole, it was 8.6 h.","PeriodicalId":100854,"journal":{"name":"Journal of Veterinary Anaesthesia","volume":"95 1","pages":"18-22"},"PeriodicalIF":0.0,"publicationDate":"1999-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85769572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

ABSTRACTS OF SCIENTIFIC PAPERS PRESENTED AT THE AUTUMN MEETING OF THE ASSOCIATION OF VETERINARY ANAESTHETISTS, GHENT, 1ST AND 2ND OCTOBER 1998 1998年10月1日和2日在根特举行的兽医麻醉师协会秋季会议上发表的科学论文摘要

Journal of Veterinary Anaesthesia Pub Date : 1999-12-01 DOI: 10.1111/j.1467-2995.1999.tb00184.x

引用次数: 0

Cardiopulmonary effects of a two hour medetomidine infusion and its antagonism by atipamezole in horses and ponies 两小时输注美托咪定对马和小马的心肺作用及其阿替帕美唑的拮抗作用

Journal of Veterinary Anaesthesia Pub Date : 1999-12-01 DOI: 10.1111/j.1467-2995.1999.tb00176.x

R. Bettschart-Wolfensberger, R.W. Bettschart, O. Vainio, D. Marlin, K.W. Clarke

{"title":"Cardiopulmonary effects of a two hour medetomidine infusion and its antagonism by atipamezole in horses and ponies","authors":"R. Bettschart-Wolfensberger, R.W. Bettschart, O. Vainio, D. Marlin, K.W. Clarke","doi":"10.1111/j.1467-2995.1999.tb00176.x","DOIUrl":"https://doi.org/10.1111/j.1467-2995.1999.tb00176.x","url":null,"abstract":"<div><p>The cardiopulmonary effects of an intravenous (iv) medetomidine injection (5 μg/kg) followed 5 min later by its infusion at 3.5 μg/kg/h for 115 rnin were studied in 9 horses and ponies. Five minutes after the end of infusion 60 μg/kg atipamezole were given. Physiological data during infusion were compared with pre-sedation values. Stroke volume was reduced significantly 5 min after initial medetomidine injection. Cardiac index was reduced significantly and systemic vascular resistance increased significantly for the first 20 min, but returned towards pre-sedation values after this time. Arterial blood pressures were reduced significantly from 30 min until the end of the procedure (minimum MAP was 102.4 ± 9.61 mmHg). Mixed venous oxygen tension was reduced significantly during the infusion. Respiratory rate fell and PaCO<sub>2</sub>- rose significantly from 40 min onward. Other variables showed no significant changes. The horses recovered rapidly after atipamezole was injected. Arterial blood pressures remained significantly lowered, but other cardiovascular variables returned towards pre-sedation values. It is concluded that the infusion of medetomidine at 3.5 μg/kg/h causes minimum cardiopulmonary depression once the effects of an initial 5 μg/kg injection have waned, and so could prove suitable as part of an anaesthetic technique in equidae.</p></div>","PeriodicalId":100854,"journal":{"name":"Journal of Veterinary Anaesthesia","volume":"26 1","pages":"Pages 8-12"},"PeriodicalIF":0.0,"publicationDate":"1999-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1467-2995.1999.tb00176.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72241861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 49

Actions and pharmacokinetic properties of the α2-adrenergic agents, medetomidine and atipamezole, in rainbow trout (Oncorhynchus mykiss) α2-肾上腺素能药物美托咪定和阿替帕美唑在虹鳟中的作用和药代动力学特性

Journal of Veterinary Anaesthesia Pub Date : 1999-12-01 DOI: 10.1111/j.1467-2995.1999.tb00179.x

T.E. Horsberg, J.F. Burka , R.A.R. Tasker

{"title":"Actions and pharmacokinetic properties of the α2-adrenergic agents, medetomidine and atipamezole, in rainbow trout (Oncorhynchus mykiss)","authors":"T.E. Horsberg, J.F. Burka , R.A.R. Tasker","doi":"10.1111/j.1467-2995.1999.tb00179.x","DOIUrl":"https://doi.org/10.1111/j.1467-2995.1999.tb00179.x","url":null,"abstract":"<div><p>The effects of medetomidine and atipamezole were examined in rainbow trout. Medetomidine proved to be an effective sedative but not an anaesthetic; its effects were antagonised by atipamezole. The clinical signs of medetomidine sedation were rapid settling to the bottom of the tank followed by progressive ataxia. The sedative effect was dose-dependent: at 1 mg/l, one of 6 fish rested on its side after 10 min, whereas at 20 mg/l all 6 rested on their sides. No loss of consciousness occurred.</p><p>Atipamezole at 6 times the medetomidine concentration antagonised sedation. The average time before fish exposed to medetomidine alone showed avoidance reactions was 10 h, more than 5 times longer than the mean time in fish exposed to medetomidine and then atipamezole.</p><p>During exposure to medetomidine (5 mg/l) opercular movement rate decreased from 80/min to 20/min. The nature of opercular excursions also changed from being rapid and shallow to slow and deep. Respiratory movements increased after transfer to the bath containing atipamezole.</p><p>Medetomidine had a marked effect upon skin colour, with fish becoming very pale a few min after exposure. Normal pigmentation was not restored until 4.5 days after exposure to medetomidine alone, but returned to normal after 10 min exposure to atipamezole solution.</p><p>The half-life (<em>t</em><sup>1</sup>/<sub>2</sub> lambda<sub>z</sub>) for medetomidine was 5.5 h. For atipamezole, it was 8.6 h.</p></div>","PeriodicalId":100854,"journal":{"name":"Journal of Veterinary Anaesthesia","volume":"26 1","pages":"Pages 18-22"},"PeriodicalIF":0.0,"publicationDate":"1999-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1467-2995.1999.tb00179.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72241862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Epidural injection of ketamine for caudal analgesia in the cow 牛硬膜外注射氯胺酮用于尾侧镇痛

Journal of Veterinary Anaesthesia Pub Date : 1999-12-01 DOI: 10.1111/j.1467-2995.1999.tb00182.x

F. Marsico, P.R.L. Nascimento, A.C. de Paula, A. Nascimento Jnr, F.J. Tendillo , A. Criado , I.A. Gómez de Segura

{"title":"Epidural injection of ketamine for caudal analgesia in the cow","authors":"F. Marsico, P.R.L. Nascimento, A.C. de Paula, A. Nascimento Jnr, F.J. Tendillo , A. Criado , I.A. Gómez de Segura","doi":"10.1111/j.1467-2995.1999.tb00182.x","DOIUrl":"https://doi.org/10.1111/j.1467-2995.1999.tb00182.x","url":null,"abstract":"<div><p>The objective of the study was to determine the analgesic and sedative effects of epidural ketamine in the cow. Eight healthy cows weighing 350–450 kg were used. One of 3 doses of ketamine (0.5, 1 and 2.0 mg/kg) or a saline control were injected into the epidural space at the first intercoccygeal interspace in random sequence at one-week intervals. Ketamine was diluted in saline (0.9%) before the experiment, and the volume adjusted according to animal size. Analgesia was tested by applying a standard stimulus (needle insertion into the skin and deep muscle) and scored using a 3-point scale. A second voltage-based stimulus was also applied and the responses scored. Another scale was used for scoring the degree of sedation. The response and the degree of sedation were assessed before drug administration and at 2, 5, 10, 15 min, and every 15 min until 120 min after ketamine or saline administration. Ketamine produced dose-related analgesia of the tail, anus, perineum and vulva but not of the hindlimb area. The effect was dose-dependent in terms of intensity and duration. None of the doses produced analgesia when 70 or 80 volts were applied. Minimal side effects were observed. Epidural ketamine produces caudal analgesia in the cow. Further studies are required to determine whether this is sufficient for surgery.</p></div>","PeriodicalId":100854,"journal":{"name":"Journal of Veterinary Anaesthesia","volume":"26 1","pages":"Pages 27-31"},"PeriodicalIF":0.0,"publicationDate":"1999-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1467-2995.1999.tb00182.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72241865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Association of Veterinary Anaesthetists: Educational Trust 兽医麻醉师协会:教育信托

Journal of Veterinary Anaesthesia Pub Date : 1999-12-01 DOI: 10.1111/J.1467-2995.1999.TB00186.X

J. Stonebridge

引用次数: 0